Pyrimidinergic Receptor P2Y, G-Protein Coupled, 4 Protéines (P2RY4)

The product of P2RY4 belongs to the family of G-protein coupled receptors. De plus, nous expédions P2RY4 Anticorps (73) et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
P2RY4 5030 P51582
P2RY4 57385 Q9JJS7
Rat P2RY4 P2RY4 63843 O35811
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Showing 3 out of 3 products:

Catalogue No. Origin Source Conjugué Images Quantité Fournisseur Livraison Prix Détails
Cellules d'insectes Souris rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Connectez-vous pour afficher 50 to 55 Days
$5,262.31
Détails
Cellules d'insectes Humain rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Connectez-vous pour afficher 50 to 55 Days
$7,493.38
Détails
Wheat germ Humain Inconjugué   2 μg Connectez-vous pour afficher 11 to 12 Days
$491.43
Détails

P2RY4 Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Human ,

Mouse (Murine)

Plus protéines pour Pyrimidinergic Receptor P2Y, G-Protein Coupled, 4 (P2RY4) partenaires d'interaction

Pig (Porcine) Pyrimidinergic Receptor P2Y, G-Protein Coupled, 4 (P2RY4) interaction partners

  1. the effect of ATP on Na+-ATPase activity could be involved in antinatriuresis induced by P2Y4 receptor or a mechanism to counterbalance the natriuretic effect of P2Y2 receptor, promoting fine control of sodium reabsorption in proximal tubule cells.

Human Pyrimidinergic Receptor P2Y, G-Protein Coupled, 4 (P2RY4) interaction partners

  1. reflected in the immunoblotting data P2RY4 receptors were detected at higher levels of expression in patient with cortical dysplasia with intractable epilepsy.

  2. P2Y4 receptors are expressed in intracellular vesicles and sarcolemma of skeletal muscle fibers.

  3. show that P2 receptors and protein kinases are also involved in regulating injury-induced expression and the release of TSP-1 in injured astrocytes

  4. Nucleotide P2Y4 receptor binding is arrested in post-Golgi trafficking by type I transmembrane proteins p23 and p24A.

  5. expression profile in human peripheral tissues and brain regions using PCR

  6. Human keratinocytes express multiple P2Y-receptors: evidence for functional P2Y1, P2Y2, and P2Y4 receptors.

  7. Activation of the human P2Y(4) receptor expressed in 1321N1 cells by UTP did not elicit this protective effect, although both receptors were coupled to phospholipase C.

  8. second extracellular loop and the NH(2) terminus form a functional motif that plays a key role in determining whether ATP functions as an agonist or antagonist at mammalian P2Y(4) receptors

  9. Taken together, our data indicate that the high expression and activation of the P2Y4 receptor participates in the neuronal differentiation and commitment to death of SH-SY5Y cells.

Mouse (Murine) Pyrimidinergic Receptor P2Y, G-Protein Coupled, 4 (P2RY4) interaction partners

  1. These data highlight the P2Y4 receptor as an inhibitor of cardiac fat formation

  2. In the brain samples, expressions of P2Y4 and P2X7 were significantly reduced, whereas that of P2Y1 was significantly elevated in an age-dependent manner.

  3. Data show that activation of nucleotide receptor P2Y4 (P2Y4) in the differentiating embryonic stem cells (ESCs) resulted in an increased proportion of neurons expressing vesicular glutamate transporter (vGluT).

  4. present study defines the P2Y4 nucleotide receptor, expressed on cardiac microvascular endothelial cells and involved in postnatal heart development, as an important regulator of the inflammatory response to cardiac ischemia

  5. Amyloid beta peptide 1-42 induced self-uptake in microglia through pinocytosis, a process involving activation of P2Y4 receptors by autocrine ATP signaling.

  6. P2Y(4) receptor could constitute an important regulator of acute and chronic response to exercise.

  7. study uncovers mouse P2Y(4) receptor as an essential regulator of cardiac endothelial cell function, and illustrates the involvement of endothelial-cardiomyocyte interactions in post-natal heart development

  8. Purinergic receptors might represent important new set of molecular targets for theca hyperplasia and polycystic ovarian syndrome.

  9. Knock-out mice reveal tissue-specific roles of P2Y receptor subtypes in different epithelia.

  10. Purinergic receptors on microglial cells: functional expression in acute brain slices and modulation of microglial activation in vitro.

  11. Both the P2Y2 and P2Y4 receptors are present in the luminal membrane of mouse distal colonic mucosa, and stimulation of these receptors leads to potassium ion secretion.

  12. The role of P2Y2 and P2Y4 receptors in peritoneal macrophage calcium signaling is reported.

  13. Functional purinergic (P2Y4) neuron-glia communication in the enteric nervous system is shown, raising the possibility that ATP released with neurotransmitters during enteric synaptic transmission functions to signal to enteric glia.

  14. AQP2-mediated water transport is downregulated not only by basolateral nucleotides, mediated by P2Y(2) receptors, but also by luminal nucleotides, mediated by P2X(2) and/or P2Y(4) receptors.

Profil protéine P2RY4

Profil protéine

The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is responsive to uridine nucleotides, partially responsive to ATP, and not responsive to ADP.

Gene names and symbols associated with P2RY4

  • pyrimidinergic receptor P2Y4 (P2RY4)
  • pyrimidinergic receptor P2Y, G-protein coupled, 4 (P2ry4)
  • pyrimidinergic receptor P2Y4 (P2ry4)
  • pyrimidinergic receptor P2Y, G-protein coupled, 4 L homeolog (p2ry4.L)
  • NRU Protéine
  • P2P Protéine
  • p2ry8 Protéine
  • P2Y4 Protéine
  • P2Y4R Protéine
  • UNR Protéine

Protein level used designations for P2RY4

P2Y purinoceptor 4 , P2Y4 nucleotide receptor , pyrimidinergic receptor P2Y4 , uridine nucleotide receptor , P2Y4 receptor , purinergic receptor P2Y, G-protein coupled, 4 , P2Y ATP receptor 4 , purinergic receptor P2Y G-protein coupled 4 , purinergic receptor P2Y, G-protein coupled 4 , P2Y purinoceptor 8 , P2Y4 , P2Y8

GENE ID SPECIES
450244 Sus scrofa
695127 Macaca mulatta
5030 Homo sapiens
57385 Mus musculus
63843 Rattus norvegicus
380035 Xenopus laevis
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