Quinolinate Phosphoribosyltransferase Protéines (QPRT)

QPRT encodes a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide pathway. De plus, nous expédions QPRT Anticorps (73) et QPRT Kits (12) et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
QPRT 23475 Q15274
QPRT 67375 Q91X91
QPRT 293504 Q5I0M2
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Top QPRT Protéines sur anticorps-enligne.fr

Showing 10 out of 15 products:

Catalogue No. Origin Source Conjugué Images Quantité Fournisseur Livraison Prix Détails
Cellules d'insectes Humain His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 50 Days
$6,869.04
Détails
Cellules d'insectes Souris His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 50 Days
$6,869.04
Détails
Escherichia coli (E. coli) Humain His tag   50 μg Connectez-vous pour afficher 4 Days
$522.50
Détails
Escherichia coli (E. coli) Humain His tag Validation with Western Blot 10 μg Connectez-vous pour afficher 8 to 11 Days
$504.90
Détails
Wheat germ Humain GST tag 10 μg Connectez-vous pour afficher 11 to 12 Days
$414.29
Détails
HEK-293 Cells Humain Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Connectez-vous pour afficher Disponible
$547.80
Détails
Escherichia coli (E. coli) Humain His tag 100 μg Connectez-vous pour afficher 15 to 19 Days
$400.00
Détails
Levure Nematostella vectensis His tag   1 mg Connectez-vous pour afficher 60 to 71 Days
$2,762.83
Détails
Levure Rat His tag   1 mg Connectez-vous pour afficher 60 to 71 Days
$2,794.00
Détails
Levure Boeuf (Vache) His tag   1 mg Connectez-vous pour afficher 60 to 71 Days
$2,794.00
Détails

QPRT Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Human , , ,
, ,
Mouse (Murine)

Rat (Rattus)

Plus protéines pour Quinolinate Phosphoribosyltransferase (QPRT) partenaires d'interaction

Human Quinolinate Phosphoribosyltransferase (QPRT) interaction partners

  1. WT1 (Montrer WT1 Protéines) knock-down gave a corresponding decrease in QPRT gene and protein expression. Chromatin-immunoprecipitation revealed WT1 (Montrer WT1 Protéines) binding to a conserved site in the first intron of the QPRT gene.

  2. The structural features, size distribution, heat aggregation and ITC studies of the full-length enzyme and the enzyme lacking helix alpha1 strongly suggest that human QPRT acts as a hexamer for cooperative reactant binding via three dimeric subunits and maintaining stability.

  3. Report of the crystal structure of human QPRT bound to its inhibitor phthalic acid (PHT) and kinetic analysis of PHT inhibition of human QPRT.

  4. QPRT is a potential new marker for the immunohistochemical screening of follicular thyroid nodules.

Profil protéine QPRT

Profil protéine

This gene encodes a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide pathway. Quinolinate acts as a most potent endogenous exitotoxin to neurons. Elevation of quinolinate levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimer's disease, and Huntington's disease.

Gene names and symbols associated with QPRT

  • quinolinate phosphoribosyltransferase (ECs0113)
  • quinolinate phosphoribosyltransferase (nadC)
  • quinolinate phosphoribosyltransferase (VP2522)
  • nicotinate-nucleotide pyrophosphorylase (STY0167)
  • nicotinate-nucleotide diphosphorylase (nadC)
  • nicotinate-nucleotide diphosphorylase (BJE04_RS13210)
  • carboxylating (nadC)
  • quinolinate phosphoribosyltransferase (QPRT)
  • quinolinate phosphoribosyltransferase (Qprt)
  • 2410027J01Rik Protéine
  • AI647766 Protéine
  • ECK0108 Protéine
  • JW0105 Protéine
  • QPRTase Protéine
  • VF2184 Protéine

Protein level used designations for QPRT

quinolinate phosphoribosyltransferase , QAPRTase , nicotinate-nucleotide pyrophosphorylase (carboxylating) , nicotinate-nucleotide pyrophosphorylase [carboxylating] , nicotinate-nucleotide pyrophosphorylase , QPRTase , quinolinate phosphoribosyltransferase (nicotinate-nucleotide pyrophosphorylase (carboxylating))

GENE ID SPECIES
913630 Escherichia coli O157:H7 str. Sakai
948869 Escherichia coli str. K-12 substr. MG1655
1176241 Yersinia pestis CO92
1178543 Vibrio vulnificus CMCP6
1190037 Vibrio parahaemolyticus RIMD 2210633
1246662 Salmonella enterica subsp. enterica serovar Typhi str. CT18
1251663 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
2625587 Vibrio vulnificus YJ016
2767301 Yersinia pestis biovar Microtus str. 91001
2885134 Pectobacterium atrosepticum SCRI1043
2956115 Yersinia pseudotuberculosis IP 32953
3277733 Vibrio fischeri ES114
3332556 Salmonella enterica subsp. enterica serovar Choleraesuis str. SC-B67
4715853 Yersinia enterocolitica subsp. enterocolitica 8081
6988234 Aliivibrio salmonicida LFI1238
8168296 Photorhabdus asymbiotica subsp. asymbiotica ATCC 43949
23475 Homo sapiens
67375 Mus musculus
293504 Rattus norvegicus
614254 Bos taurus
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