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Controls vesicular trafficking from endosomes to the trans-Golgi network (TGN). De plus, nous expédions RAB7B Protéines (9) et beaucoup plus de produits pour cette protéine.
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Human Monoclonal RAB7B Primary Antibody pour IP, ELISA - ABIN567027
Zhu, Salazar, Zlatic, Fiza, Doucette, Heilman, Levey, Faundez, Lhernault: SPE-39 family proteins interact with the HOPS complex and function in lysosomal delivery. dans Molecular biology of the cell 2009
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Human Polyclonal RAB7B Primary Antibody pour WB - ABIN1881722
Progida, Cogli, Piro, De Luca, Bakke, Bucci: Rab7b controls trafficking from endosomes to the TGN. dans Journal of cell science 2010
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study demonstrates that Rab7b regulates LC3 (Montrer MAP1LC3A Anticorps) processing by modulating Atg4B (Montrer ATG4B Anticorps) activity; taken together, findings reveal Rab7b as a novel negative regulator of autophagy through its interaction with Atg4B (Montrer ATG4B Anticorps)
Authors determined the effects of T. suis soluble products (SPs (Montrer SMS Anticorps)) on Toll-like receptor-4 (TLR4 (Montrer TLR4 Anticorps))- In addition, T. suis SPs (Montrer SMS Anticorps) induce Rab7b, a negative regulator of TLR4 (Montrer TLR4 Anticorps) signalling
Rab9a (Montrer RAB9A Anticorps) and Rab7b are mediators of the transit of the L2 capsid protien and the pseudogenome of human papillomavirus 16 from the late endosome to the golgi complex.
Rab7b is required for sortilin (Montrer SORT1 Anticorps) transport from endosomes to the TGN (Montrer TG Anticorps).
Rab7b may play important roles in megakaryopoiesis by activating NF-kappaB (Montrer NFKB1 Anticorps) and promoting IL-6 (Montrer IL6 Anticorps) production.
Rab7b is required for normal lysosome function, and, in particular, it is an essential factor for retrograde transport from endosomes to the trans-Golgi network.
Controls vesicular trafficking from endosomes to the trans-Golgi network (TGN). Acts as a negative regulator of TLR9 signaling and can suppress TLR9-triggered TNFA, IL6, and IFNB production in macrophages by promoting TLR9 lysosomal degradation. Also negatively regulates TLR4 signaling in macrophages by promoting lysosomal degradation of TLR4. Promotes megakaryocytic differentiation by increasing NF-kappa-B-dependent IL6 production and subsequently enhancing the association of STAT3 with GATA1. Not involved in the regulation of the EGF- and EGFR degradation pathway (By similarity).
ras-related protein Rab-7b
, rab7B protein
, RAB7B, member RAS oncogene family
, Ras-related protein Rab-7