RAS, Dexamethasone-Induced 1 Protéines (RASD1)

RASD1 encodes a member of the Ras superfamily of small GTPases and is induced by dexamethasone. De plus, nous expédions RASD1 Anticorps (31) et RASD1 Kits (8) et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
RASD1 51655 Q9Y272
RASD1 19416 O35626
RASD1 64455 Q9JKF8
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Showing 5 out of 7 products:

Catalogue No. Origin Source Conjugué Images Quantité Fournisseur Livraison Prix Détails
Cellules d'insectes Humain His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 50 Days
$6,869.04
Détails
Cellules d'insectes Souris His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 50 Days
$6,869.04
Détails
Wheat germ Humain GST tag 2 μg Connectez-vous pour afficher 11 to 12 Days
$225.40
Détails
Levure Rat His tag   1 mg Connectez-vous pour afficher 60 to 71 Days
$2,724.33
Détails
Escherichia coli (E. coli) Boeuf (Vache) Inconjugué   5 applications Connectez-vous pour afficher 1 to 2 Days
$318.85
Détails

RASD1 Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Human , ,
,
Mouse (Murine)

Rat (Rattus)

Plus protéines pour RAS, Dexamethasone-Induced 1 (RASD1) partenaires d'interaction

Human RAS, Dexamethasone-Induced 1 (RASD1) interaction partners

  1. Studies indicate potential roles for Rasd1 small G protein (Montrer RAC2 Protéines) and leptin (Montrer LEP Protéines) in TRPC4 (Montrer TRPC4 Protéines) cation channel (Montrer TRPV1 Protéines) activation.

  2. Data indicate that protein kinase A (PKA) phosphorylates only serine-253 amino acid on activator of G-protein signaling 1 protein Dexras1 (RASD1).

  3. Loss of RASD1 is associated with prostate cancer.

  4. Study showed that Rasd1 and NonO (Montrer NONO Protéines) interact at the CRE-site of specific target genes.

  5. Rasd1 modulates endogenous renin (Montrer REN Protéines) gene expression by interacting with Ear2 (Montrer NR2F6 Protéines).

  6. A glucocorticoid response element (GRE) was identified in the 3'-flanking region (2.3 kb downstream of poly(A) signal) of the human Dexras1 gene. A point mutation within the 15-bp GRE abolished this glucocorticoid responsiveness

  7. yeast two hybrid analysis and co-immunoprecipitation studies in mammalian cells demonstrate a direct interaction between AGS1 (Montrer TREX1 Protéines) and the G(beta1) subunit of heterotrimeric G proteins

  8. does not alter the membrane translocation of protein kinase C delta (Montrer PKCd Protéines).

  9. Dexras1 plays a critical role in shaping the photic phase response curve (PRC) and the signaling events through which it regulates clock entrainment in transgenic mice.

  10. dex-ras1 mRNA is not induced by glucocorticoid stimulation in HEK293 cells

Mouse (Murine) RAS, Dexamethasone-Induced 1 (RASD1) interaction partners

  1. These results suggest that Dexras1 is a critical mediator of the IGF-1 (Montrer IGF1 Protéines) signal to activate MAPK (Montrer MAPK1 Protéines), linking glucocorticoid signaling to IGF-1 (Montrer IGF1 Protéines) signaling in adipogenesis.

  2. These findings suggest that RASD1 acts as a novel signaling molecule and plays an important role in regulating dynamic uterine remodeling during the estrous cycle in the uterus.

  3. This study demonstrated that provide unprecedented evidence for a selective epigenetic up-regulation of Dexras 1 gene expression in the striatum of EAE mice.

  4. RASD1 is a novel factor in Metaphase I-Metaphase II oocyte transition and may be involved in regulating the progression of cytokinesis and spindle formation

  5. Results suggest a potential role for Dexras1 in modulating a selective subset of psychiatric symptoms, possibly via its interaction with NMDARs and/or other disease-related binding-partners

  6. two mechanisms of Rasd1 induction in the hypothalamus, were identified.

  7. Lysosomal iron modulates NMDA receptor-mediated excitation via small GTPase (Montrer RACGAP1 Protéines), Dexras1

  8. Dexras1 mediates adipogenesis and diet-induced obesity.

  9. Dexras1 is involved in the circadian clock regulation

  10. Dexras1 appears to mediate N-methylaspartate (NMDA)-elicited neurotoxicity via nitric oxide and iron influx.

Profil protéine RASD1

Profil protéine

This gene encodes a member of the Ras superfamily of small GTPases and is induced by dexamethasone. The encoded protein is an activator of G-protein signaling and acts as a direct nucleotide exchange factor for Gi-Go proteins. This protein interacts with the neuronal nitric oxide adaptor protein CAPON, and a nuclear adaptor protein FE65, which interacts with the Alzheimer's disease amyloid precursor protein. This gene may play a role in dexamethasone-induced alterations in cell morphology, growth and cell-extracellular matrix interactions. Epigenetic inactivation of this gene is closely correlated with resistance to dexamethasone in multiple myeloma cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with RASD1

  • ras related dexamethasone induced 1 (RASD1)
  • RAS, dexamethasone-induced 1 (Rasd1)
  • ras related dexamethasone induced 1 (Rasd1)
  • AGS1 Protéine
  • Dexras1 Protéine
  • MGC:26290 Protéine

Protein level used designations for RASD1

activator of G-protein signaling 1 , dexamethasone-induced Ras-related protein 1 , ras-related protein , DEXRAS1 (Dexras1)

GENE ID SPECIES
51655 Homo sapiens
19416 Mus musculus
64455 Rattus norvegicus
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