anti-RASD Family, Member 2 (RASD2) Anticorps

RASD2 encodes a Ras-related protein that enriched in striatum. De plus, nous expédions RASD Family, Member 2 Protéines (8) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
RASD2 23551 Q96D21
RASD2 171099 P63033
RASD2 75141 P63032
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Top anti-RASD Family, Member 2 Anticorps sur anticorps-enligne.fr

Showing 10 out of 98 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Livraison Prix Détails
Humain Lapin Inconjugué WB Western blot analysis of RASD2 expression in HEK293T (A), A549 (B), Hela (C) whole cell lysates. 200 μL 13 to 14 Days
$487.50
Détails
Humain Lapin Inconjugué ELISA, IHC, IHC (p), WB Human Kidney (formalin-fixed, paraffin-embedded) stained with RASD2 antibody ABIN461905 at 2.5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Human Pancreas (formalin-fixed, paraffin-embedded) stained with RASD2 antibody ABIN461905 at 2.5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg 11 to 14 Days
$616.00
Détails
Humain Lapin Inconjugué EIA, WB RASD2 Antibody (Center) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the RASD2 antibody detected the RASD2 protein (arrow). 0.4 mL 6 to 8 Days
$484.00
Détails
Humain Souris Inconjugué FACS, IF, WB 100 μL 11 to 14 Days
$522.50
Détails
Humain Souris Inconjugué FACS, WB 100 μL 11 to 14 Days
$522.50
Détails
Humain Lapin Inconjugué ELISA, WB   100 μg 2 to 3 Days
$302.50
Détails
Humain Lapin Inconjugué ELISA, ICC, IF, WB ABIN6274472 staining Hela by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25°C. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody. Western blot analysis of extracts from Jurkat cells, using RASD2 antibody. 100 μL 11 to 12 Days
$390.77
Détails
Humain Souris Inconjugué FACS, IF, IHC, WB Anti-RASD2 mouse monoclonal antibody (ABIN2453961) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY RASD2 (RC201454). HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY RASD2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-RASD2. 0.1 mL 2 to 3 Days
$462.00
Détails
Humain Lapin Inconjugué EIA, IHC (p), WB   0.1 mg 4 to 8 Days
$522.50
Détails
Humain Lapin Inconjugué EIA, IHC (p), WB   0.1 mg 4 to 8 Days
$522.50
Détails

anti-RASD Family, Member 2 Anticorps mieux référencés

  1. Human Polyclonal RASD2 Primary Antibody pour IHC (p), WB - ABIN541648 : Carson-Walter, Watkins, Nanda, Vogelstein, Kinzler, St Croix: Cell surface tumor endothelial markers are conserved in mice and humans. dans Cancer research 2001 (PubMed)
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  2. Human Polyclonal RASD2 Primary Antibody pour IHC (p), WB - ABIN541647 : Vargiu, Morte, Manzano, Perez, de Abajo, Gregor Sutcliffe, Bernal: Thyroid hormone regulation of rhes, a novel Ras homolog gene expressed in the striatum. dans Brain research. Molecular brain research 2001 (PubMed)
    Show all 3 Pubmed References

  3. Human Polyclonal RASD2 Primary Antibody pour IHC, ELISA - ABIN1003257 : Spano, Branchi, Rosica, Pirro, Riccio, Mithbaokar, Affuso, Arra, Campolongo, Terracciano, Macchia, Bernal, Alleva, Di Lauro: Rhes is involved in striatal function. dans Molecular and cellular biology 2004 (PubMed)
    Show all 4 Pubmed References

  4. Human Polyclonal RASD2 Primary Antibody pour IHC, ELISA - ABIN1003258 : Yamamoto, Irie, Asada, Mino, Mandai, Takai: Direct binding of the human homologue of the Drosophila disc large tumor suppressor gene to seven-pass transmembrane proteins, tumor endothelial marker 5 (TEM5), and a novel TEM5-like protein. dans Oncogene 2004 (PubMed)
    Show all 4 Pubmed References

  5. Human Monoclonal RASD2 Primary Antibody pour FACS, ICC - ABIN4349408 : Lu, Palacino: A novel human embryonic stem cell-derived Huntington's disease neuronal model exhibits mutant huntingtin (mHTT) aggregates and soluble mHTT-dependent neurodegeneration. dans FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2013 (PubMed)

Plus d’anticorps contre RASD Family, Member 2 partenaires d’interaction

Human RASD Family, Member 2 (RASD2) interaction partners

  1. results support the hypothesis that Rhes expression is regulated by miRNA and indicate that miR-101 may be a potent modulator of Rhes expression in striatal neurons.

  2. Study demonstrated that variation in the gene coding for RASD2 (rs6518956) affects in vivo prefrontal and striatal phenotypes in healthy human subjects that are relevant to schizophrenia

  3. Rhes influences striatal cAMP/PKA-dependent signaling and synaptic plasticity in a gender-sensitive fashion

  4. Findings reveal that ras homolog enriched in striatum is localized also in striatal cholinergic interneurons and, most importantly, lack of this G-protein, significantly alters dopamine D2 receptor modulation of striatal cholinergic excitability.

  5. Rhes is reduced in the brains of Huntington's disease patients.

  6. The findings of this study suggested that Rhes may play a crucial role in striatal iron homeostasis.

  7. Rhes robustly binds the autophagy regulator Beclin-1, decreasing its inhibitory interaction with Bcl-2 independent of JNK-1 signaling.

  8. The sequestering of Rhes through its binding to mutant huntingtin may decrease the ability of Rhes to perform vital physiological functions in the striatum neurons of Huntington disease patients. (Review)

  9. Rhes is an imidazoline-regulated transcript in pancreatic beta-cells

  10. Rhes can interfere with the functional activity of wt and mutated TSHr and with the respective hormone-stimulated cAMP production of FSHr and LHr.

  11. The genes RASD2 might be vulnerability genes for neuropsychologically defined subgroups of schizophrenic patients.

  12. The monomeric G proteins AGS1 and Rhes selectively influence Galphai-dependent signaling to modulate N-type (CaV2.2) calcium channels.

  13. Binding to the Gbeta subunits involves the cationic regions of AGS1 and Rhes, and Data used Rhes-AGS1 chimeras to show that their different cationic regions determine the Gbeta-specificity of the interactions.

Mouse (Murine) RASD Family, Member 2 (RASD2) interaction partners

  1. guanine nucleotide exchange factor RasGRP1 inhibited Rhes-mediated control of striatal motor activity in mice. RasGRP1 stabilized Rhes, increasing its synaptic accumulation in the striatum.

  2. that Rasd2 mutants display deficits in basal prepulse inhibition that, in turn, exacerbate gating disruption under psychotomimetic drug challenge

  3. Study showed that both genetic deletion of Rhes and pharmacological blockade of mTORC1 significantly attenuate dyskinesia development by reducing the sensitization of striato-nigral medium-sized spiny neurons to levodopa

  4. ectopic expression of Rhes in the cerebellum of N171-82Q mice, during the asymptomatic period led to an exacerbation of motor deficits, including loss of balance and motor incoordination with ataxia-like features

  5. Rhes influences striatal cAMP/PKA-dependent signaling and synaptic plasticity in a gender-sensitive fashion

  6. Brain Rhes expression is decreased in a mouse model of Huntington's disease.

  7. Rhes robustly binds the autophagy regulator Beclin-1, decreasing its inhibitory interaction with Bcl-2 independent of JNK-1 signaling.

  8. Rhes is necessary for Akt dephosphorylation by the striatal multi-protein complex

  9. behavioral symptoms of HD are regulated by Rhes

  10. This study demonstrated that Rhes-deleted mice are dramatically protected from neurotoxicity and motor dysfunction in a striatal-specific model of Huntington's disease elicited by 3-nitropropionic acid.

  11. Ths results of this study indicted that Rhes physiologically binds to and activates mTOR in the striatum and L-DOPA-induced dyskinesia.

  12. Rhes disruption affects selected behavioral competencies, including a gender-dependent increase in anxiety levels and a clear motor coordination deficit but no learning or memory impairment.

  13. The absence of Rhes modulates cAMP/PKA signalling in both striatopallidal and striatonigral projection neurons by increasing Golf protein levels and, in turn, influencing motor responses challenged by dopaminergic agonist/antagonist.

RASD Family, Member 2 (RASD2) profil antigène

Profil protéine

This gene encodes a Ras-related protein that enriched in striatum. The product of this gene binds to GTP and possesses intrinsic GTPase activity. The gene belongs to the Ras superfamily of small GTPases. The exact function of this gene is unknown, but most striatum-specific mRNAs characterized to date encode components of signal transduction cascades.

Gene names and symbols associated with RASD2

  • RASD family member 2 (RASD2) anticorps
  • RASD family, member 2 (Rasd2) anticorps
  • 4930526B11Rik anticorps
  • AU045414 anticorps
  • MGC:4834 anticorps
  • RASD2 anticorps
  • Rhes anticorps
  • TEM-2 anticorps
  • TEM2 anticorps

Protein level used designations for RASD2

RASD family, member 2 , GTP-binding protein Rhes , Ras homolog enriched in striatum , tumor endothelial marker 2 , SE6C , ras homolog enriched in striatum

GENE ID SPECIES
418057 Gallus gallus
470196 Pan troglodytes
527921 Bos taurus
23551 Homo sapiens
171099 Rattus norvegicus
481284 Canis lupus familiaris
75141 Mus musculus
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