RalA Binding Protein 1 Protéines (RALBP1)

Can activate specifically hydrolysis of GTP bound to RAC1 and CDC42, but not RALA. De plus, nous expédions RALBP1 Anticorps (140) et RALBP1 Kits (10) et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
RALBP1 19765 Q62172
RALBP1 84014 Q62796
RALBP1 10928 Q15311
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Top RALBP1 Protéines sur anticorps-enligne.fr

Showing 7 out of 14 products:

Catalogue No. Origin Source Conjugué Images Quantité Fournisseur Livraison Prix Détails
Cellules d'insectes Humain His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 60 Days
$9,797.11
Détails
Cellules d'insectes Souris His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 60 Days
$9,797.11
Détails
Escherichia coli (E. coli) Humain His tag 100 μg Connectez-vous pour afficher 15 to 18 Days
$778.00
Détails
HEK-293 Cells Humain Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Connectez-vous pour afficher Disponible
$814.00
Détails
Wheat germ Humain GST tag 10 μg Connectez-vous pour afficher 11 to 12 Days
$414.29
Détails
Escherichia coli (E. coli) Souris His tag   100 μg Connectez-vous pour afficher 15 to 18 Days
$800.00
Détails
Escherichia coli (E. coli) Rat His tag   100 μg Connectez-vous pour afficher 15 to 18 Days
$816.00
Détails

RALBP1 Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Mouse (Murine) ,

Rat (Rattus)

Human , , ,
, ,

Plus protéines pour RalA Binding Protein 1 (RALBP1) partenaires d'interaction

Xenopus laevis RalA Binding Protein 1 (RALBP1) interaction partners

  1. Affects dynamics of the actin cytoskeleton, signalling from Ral (Montrer rala Protéines) to RLIP is required for gastrulation.

  2. These results demonstrate that to participate in the control of the actin cytoskeleton, RLIP needs its complete N-terminal region coding for the mu2BD and the GAP domain.

Mouse (Murine) RalA Binding Protein 1 (RALBP1) interaction partners

  1. The results show that ARNO (Montrer CYTH2 Protéines) interaction with the RLIP76 N-terminus regulates cell spreading and motility via PI3K and Arf6 (Montrer ARF6 Protéines), independent of RLIP76 control of Rac (Montrer AKT1 Protéines).

  2. RLIP76 acts as a scaffold at recycling endosomes by binding activated R-Ras, recruiting ARNO (Montrer CYTH2 Protéines) to activate Arf6 (Montrer ARF6 Protéines), thereby contributing to cell spreading and migration.

  3. a fundamental role of RLIP76 in regulating the function of obesity-promoting pro-inflammatory cytokines

  4. RalBP1 is a gene regulating the seizure threshold and synaptic inhibition in mice

  5. results establish that RLIP76 is required for efficient endothelial cell function and angiogenesis in solid tumors

  6. RLIP76 represents a mechanistically significant target for developing effective interventions in aggressive and refractory pancreatic cancers

  7. Studies confirmed a model in which RLIP76 plays a central role in the pathogenesis of metabolic syndrome and RLIP76 loss causes profound and global alterations of MSy signaling functions.

  8. Findings show a fundamental role of RLIP76 in chemical carcinogenesis.

  9. Because RLIP76 is induced by oxidative stress, it could play a role in insulin (Montrer INS Protéines) resistance seen in pathological conditions characterized by increased oxidative stress

  10. Data show that RLIP76 knockout mice are extremely sensitive to irradiation.

Human RalA Binding Protein 1 (RALBP1) interaction partners

  1. RLIP76 plays a critical role in cellular proliferation, apoptosis, cell cycle distribution, cell movement and invasion in melanoma

  2. In the exons and exon-intron boundaries of ABCB5 (Montrer ABCB5 Protéines) and RLIP76 genes.

  3. the miR143-3p level was markedly lower in participants with ovarian cancer compared with normal control, while the expression of RALBP1 mRNA and protein were evidently overexpressed in participants with ovarian cancer compared with normal control.

  4. RLIP76 knockdown increased autophagic flux and apoptosis in U251 glioma cells.

  5. Phosphorylation level of Akt (Montrer AKT1 Protéines) declined from 138.45+/-13.8 to 69.9+/-29.7% in SGC (Montrer SGCB Protéines)-7901, and from 115.5+/-26.6 to 49.07+/-27% in MGC-803 and phosphorylation level of mTOR (Montrer FRAP1 Protéines) also significantly decreased.While apoptosis of gastric cancer(GA) cells increased which we verified with apoptosis proteins and staining analysis. Our data showed that RLIP76 plays a significant oncogenic role in GC and it maybe a potential target in GC

  6. Anti-tumor effect was exerted when miR (Montrer MLXIP Protéines)-124 directly targeted RLIP76, a stress-inducible transporter that plays a crucial role in the development of melanoma.

  7. report showed that RLIP76 expression was significantly increased in breast cancer samples and positively correlated with the malignant status of breast cancer patients; results indicated that high RLIP76 expression was associated with poor prognosis of breast cancer patients

  8. RLIP76 expression is induced by TNF-alpha (Montrer TNF Protéines) and follows the induction kinetics of inflammation markers, suggesting that inflammation can influence RLIP76 expression at the blood brain barrier.

  9. RLIP76 downregulation in HT29 CRC (Montrer CALR Protéines) cells suppressed cell growth, enhanced cell apoptosis, induced cell cycle arrest, and inhibited cell invasion by decreasing MMP2 (Montrer MMP2 Protéines) expression.

  10. High RLIP76 expression is associated with a poor outcome of meningioma.

Profil protéine RALBP1

Profil protéine

Can activate specifically hydrolysis of GTP bound to RAC1 and CDC42, but not RALA. Mediates ATP-dependent transport of S-(2,4-dinitrophenyl)-glutathione (DNP-SG) and doxorubicin (DOX) and is the major ATP-dependent transporter of glutathione conjugates of electrophiles (GS-E) and DOX in erythrocytes. Can catalyze transport of glutathione conjugates and xenobiotics, and may contribute to the multidrug resistance phenomenon. Serves as a scaffold protein that brings together proteins forming an endocytotic complex during interphase and also with CDK1 to switch off endocytosis, One of its substrates would be EPN1/Epsin (By similarity).

Gene names and symbols associated with RALBP1

  • ralA binding protein 1 S homeolog (ralbp1.S)
  • ralA binding protein 1 (RALBP1)
  • ralA binding protein 1 (ralbp1)
  • ralA binding protein 1 (Ralbp1)
  • RALBP1 Protéine
  • RIP1 Protéine
  • rlip-A Protéine
  • RLIP1 Protéine
  • RLIP76 Protéine

Protein level used designations for RALBP1

ralA binding protein 1 , Ral interacting protein , ralA-binding protein 1 , ralA-binding protein 1-like , DNP-SG ATPase , Ral-interacting protein 1 , dinitrophenyl S-glutathione ATPase , cytocentrin , ral-interacting protein 1 , 76 kDa Ral-interacting protein

GENE ID SPECIES
394288 Xenopus laevis
429466 Gallus gallus
455292 Pan troglodytes
523324 Bos taurus
100379815 Xenopus (Silurana) tropicalis
100431225 Pongo abelii
100478485 Ailuropoda melanoleuca
100519155 Sus scrofa
100549203 Meleagris gallopavo
100557384 Anolis carolinensis
100600679 Nomascus leucogenys
19765 Mus musculus
84014 Rattus norvegicus
10928 Homo sapiens
490548 Canis lupus familiaris
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