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RNF41 encodes an E3 ubiquitin ligase. De plus, nous expédions RNF41 Anticorps (46) et RNF41 Protéines (9) et beaucoup plus de produits pour cette protéine.
Authors conclude that the planar cell polarity (PCP (Montrer PRCP Kits ELISA)) pathway contributes significantly to the motility and hence the invasiveness of glioblastoma multiforme (GBM) cells, and that Nrdp1 acts as a negative regulator of PCP (Montrer PRCP Kits ELISA) signaling by inhibiting Dvl (Montrer DVL2 Kits ELISA) through a novel polyubiquitination mechanism.
Data suggest that PHLPP1 (Montrer PHLPP1 Kits ELISA) plays an important role in assembly of kinetochores by counteracting RNF41-mediated SGT1 (Montrer SUGT1 Kits ELISA) degradation. (PHLPP1 (Montrer PHLPP1 Kits ELISA) = PH domain and leucine rich repeat protein phosphatase 1 (Montrer PHLPP1 Kits ELISA); RNF41 = ring finger protein 41; SGT1 (Montrer SUGT1 Kits ELISA) = suppressor of G2 allele of SKP1 (Montrer SUGT1 Kits ELISA))
Results show low expression level of NRDP1 in colorectal neoplasm independently of tumor stage.
findings suggest that HBx promotes the progression of hepatocellular carcinoma by decreasing the stability of Nrdp1, which results in up-regulation of ErbB3 (Montrer ERBB3 Kits ELISA)
the association between RNF41 polymorphisms and congenital heart disease in the Chinese Mongolian population
Nrdp1S is a tumour suppressor that which potentiates the Nrdp1-mediated ubiquitination and degradation of ErbB3 (Montrer ERBB3 Kits ELISA). An Nrdp1S deficiency may also be an important factor in the loss of Nrdp1.
HPV 16 E2 can modulate ErbB-3 (Montrer ERBB3 Kits ELISA) by interacting with Nrdp-1, which is involved in the regulation of this receptor, via ubiquitination and degradation.
The results of this study suggested that Nrdp1-mediated ErbB3 (Montrer ERBB3 Kits ELISA) degradation suppresses glioma migration and invasion and that loss of Nrdp1 may amplify ErbB3 (Montrer ERBB3 Kits ELISA) signaling to contribute to glioma migration and invasion.
ABPN downregulates multiple components of the EGFR (Montrer EGFR Kits ELISA)/ErbB3 (Montrer ERBB3 Kits ELISA) signaling pathway through Nrdp1 activation.
Nrdp1 may serve as a useful biomarker for the clinical outcome and efficacy of adjuvant anthracyclines-based chemotherapy in breast cancer.
Data suggest that ring finger protein 41 Nrdp1 terminates T cell antigen receptors (TCRs) signaling by inactivating Zap70 (Montrer ZAP70 Kits ELISA) kinase.
The novel Pdx1 (Montrer PDX1 Kits ELISA)-Clec16a (Montrer CLEC16A Kits ELISA)-Nrdp1 pathway this study describes provides a genetic basis for the pathogenesis of mitochondrial dysfunction in multiple forms of diabetes.
demonstrate that Nrdp1-mediated ubiquitination and activation of C/EBPbeta (Montrer CEBPB Kits ELISA) contributes to a ubiquitin-dependent nonproteolytic pathway that up-regulates Arg1 (Montrer ARG1 Kits ELISA) expression and promotes M2 macrophage polarization
Nrdp1 may be a key mediator in the development of cardiac dysfunction after DOX treatment and associated with inhibition of Akt (Montrer AKT1 Kits ELISA), ERK1/2 (Montrer MAPK1/3 Kits ELISA) and STAT3 (Montrer STAT3 Kits ELISA).
these results provide evidence for an important role for Nrdp1 in regulating ischemia/reperfusioninduced cardiac injury
Post-transcriptional mechanisms contribute to the suppression of the ErbB3 (Montrer ERBB3 Kits ELISA) negative regulator protein Nrdp1 in mammary tumors.
Rnf41 is nominated as a candidate gene for anxiety-like behaviors, depression, and vulnerability to seizures.
Data suggest that Nrdp1 functions as both an adaptor protein and an E3 unbiquitin ligase to regulate TLR responses in different ways.
Nrdp1 is associated with differentiation process of the melanocyte lineage by regulating Erbb3b, an Erbb (Montrer EGFR Kits ELISA) signaling molecule along zebrafish embryogenesis.
This gene encodes an E3 ubiquitin ligase. The encoded protein plays a role in type 1 cytokine receptor signaling by controlling the balance between JAK2-associated cytokine receptor degradation and ectodomain shedding. Alternative splicing results in multiple transcript variants.
E3 ubiquitin-protein ligase NRDP1
, fetal liver ring finger
, neuregulin receptor degradation protein-1