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The protein encoded by S100A3 is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs.
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S100A3 expression is significantly upregulated in human masticatory mucosa during wound healing
One disulfide bridge is between Cys30 in the N-terminal pseudo-EF-hand and Cys68 in the C-terminal EF-hand (SS1), and another disulfide bridge attaches Cys99 in the C-terminal coil structure to Cys81 in helix IV (SS2).
crystal structure of S100A3 at 1.7-A resolution
structure was solved by MIRAS (Montrer POLG Protéines) phasing
Purification and characterization of the S100A3 protein from human hair cuticles.
cytoplasmic S100A3 within the cuticular layer is mostly co-localized with the type III isoform of peptidylarginine deiminase (PAD3)
S100A3 is a new target gene of Kaiso (Montrer ZBTB33 Protéines) in mouse skin
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein has the highest content of cysteines of all S100 proteins, has a high affinity for Zinc, and is highly expressed in human hair cuticle. The precise function of this protein is unknown.
S100 calcium binding protein A3
, S100 calcium-binding protein A3
, protein S100-A3