SAM and SH3 Domain Containing 1 Protéines (SASH1)

May have a role in a signaling pathway. De plus, nous expédions SASH1 Anticorps (67) et et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
SASH1 23328 O94885
SASH1 70097 P59808
Rat SASH1 SASH1 365037  
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Showing 3 out of 3 products:

Catalogue No. Origin Source Conjugué Images Quantité Fournisseur Livraison Prix Détails
Cellules d'insectes Humain His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 70 Days
$12,127.90
Détails
Cellules d'insectes Souris His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 70 Days
$12,127.90
Détails
Wheat germ Humain GST tag 10 μg Connectez-vous pour afficher 11 to 12 Days
$414.29
Détails

SASH1 Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Human ,
,
Mouse (Murine)

Plus protéines pour SAM and SH3 Domain Containing 1 (SASH1) partenaires d'interaction

Human SAM and SH3 Domain Containing 1 (SASH1) interaction partners

  1. SASH1 is prognostic in breast cancer and could have subtype-dependent effects on breast cancer progression.

  2. SASH1 may inhibit hepatocarcinoma cell invasion and metastasis through down-regulating the Shh (Montrer SHH Protéines)-Gli1 (Montrer GLI1 Protéines) and PI3K (Montrer PIK3CA Protéines)-AKT (Montrer AKT1 Protéines) pathways

  3. Case Report: SASH1 missense mutation in a Chinese Family with multiple lentigines.

  4. SASH1 acts through NOTCH1 (Montrer NOTCH1 Protéines) and its inhibitor DLK1 (Montrer DLK1 Protéines) in a three-dimensional model of lumenogenesis involving CEACAM1 (Montrer CEACAM1 Protéines).

  5. SASH1 is cleaved by caspase-3 (Montrer CASP3 Protéines) following Ultraviolet C-induced apoptosis.

  6. a novel p53 (Montrer TP53 Protéines)/POMC (Montrer POMC Protéines)/Galphas (Montrer GNAS Protéines)/SASH1 autoregulatory positive feedback loop is regulated by SASH1 mutations to induce pathological hyperpigmentation phenotype.

  7. Overexpression of SASH1 inhibits TGF-beta1 (Montrer TGFB1 Protéines)-induced EMT (Montrer ITK Protéines).

  8. Overexpression of SASH1 suppressed the expression of Shh (Montrer SHH Protéines).

  9. The loss or inhibition of SASH1 expression may play an important role in thyroid cancer development, invasion, and metastasis.

  10. Two SNPs were significantly associated with rotator cuff tearing, residing in SAP30BP (Montrer SAP30BP Protéines) on chromosome 17 and SASH1 on chromosome 6.

Mouse (Murine) SAM and SH3 Domain Containing 1 (SASH1) interaction partners

  1. SASH1 acts to assemble a signaling complex downstream of TLR4 (Montrer TLR4 Protéines) to activate early endothelial responses to receptor activation.

  2. Not expressed in the investigated haematopoietic cell lines, while transcripts were found in whole splenic B-cells from both wild type and Btk (Montrer BTK Protéines)-defective mice.

Profil protéine SASH1

Profil protéine

May have a role in a signaling pathway. Could act as a tumor suppressor.

Gene names and symbols associated with SASH1

  • SAM and SH3 domain containing 1a (sash1a)
  • SAM and SH3 domain containing 1 (SASH1)
  • SAM and SH3 domain containing 1 (sash1)
  • SAM and SH3 domain containing 1 (Sash1)
  • 1100001C18Rik Protéine
  • 2500002E12Rik Protéine
  • A330076K04Rik Protéine
  • dJ323M4 Protéine
  • dJ323M4.1 Protéine
  • fi33a01 Protéine
  • ik:tdsubc_2e1 Protéine
  • MGC162728 Protéine
  • mKIAA0790 Protéine
  • RGD1566017 Protéine
  • SH3D6A Protéine
  • tdsubc_2e1 Protéine
  • wu:fi33a01 Protéine
  • xx:tdsubc_2e1 Protéine

Protein level used designations for SASH1

SAM and SH3 domain containing 1 , SAM and SH3 domain-containing protein 1-like , 2500002E12Rik , SAM and SH3 domain-containing protein 1 , proline-glutamate repeat-containing protein , putative adapter and scaffold protein 1

GENE ID SPECIES
557132 Danio rerio
100230822 Taeniopygia guttata
100413411 Callithrix jacchus
100469850 Ailuropoda melanoleuca
100540632 Meleagris gallopavo
100553892 Anolis carolinensis
100596695 Nomascus leucogenys
23328 Homo sapiens
70097 Mus musculus
421621 Gallus gallus
608649 Canis lupus familiaris
539603 Bos taurus
365037 Rattus norvegicus
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