SHC SH2-Domain Binding Protein 1 (SHCBP1) Kits ELISA

May play a role in signaling pathways governing cellular proliferation, cell growth and differentiation. De plus, nous expédions SHCBP1 Anticorps (33) et SHCBP1 Protéines (4) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
SHCBP1 79801 Q8NEM2
SHCBP1 20419 Q9Z179
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Top SHCBP1 Kits ELISA sur

Showing 3 out of 5 products:

Catalogue No. Reactivité Sensibilité Gamme Images Quantité Livraison Prix Détails
Humain < 0.188 ng/mL 0.313 ng/mL - 20 ng/mL   96 Tests 11 to 18 Days
Souris < 0.094 ng/mL 0.156 ng/mL - 10 ng/mL   96 Tests 11 to 18 Days
Lapin 37.5 ng/mL 62.5 ng/mL - 4000 ng/mL   96 Tests 11 to 18 Days

Plus Kits ELISA pour SHCBP1 partenaires d'interaction

Human SHC SH2-Domain Binding Protein 1 (SHCBP1) interaction partners

  1. SHCBP1, a member of Src homolog and collagen homolog (Shc) family, was significantly overexpressed in glioma tissues and glioma cell lines compared to the corresponding normal tissues and cells. Ectopic overexpression of SHCBP1 promoted glioma cell migration and invasion, whereas knockdown of endogenous SHCBP1 had the opposite effects. SHCBP1 promoted aggressiveness in gliomas by activating the NF-kappaB signaling path...

  2. Study revealed that SHCBP1 may play a role in cell growth and metastasis and may be a potential diagnosis biomarker and therapeutic target for gastric cancer.

  3. study establishes a novel convergence between EGFR and beta-catenin pathways and highlights a potential significance of SHCBP1 as a prognostic biomarker and a therapeutic target.

  4. SHCBP1 was found highly expressed in SS cell lines and tissues, which was linked to the poor clinical prognosis and was implicated in SS aggressive progression. SHCBP1 regulated invasion and metastasis by modulating the TGF-beta1/Smad signaling pathway and promoting the EMT in SS.

  5. Data indicate that the oncogene SS18-SSX1 promotes tumorigenesis by increasing the expression of SHC SH2-domain binding protein 1 (SHCBP1), which normally acts as a tumor promoting factor.

  6. Immunohistochemical analysis revealed SHCBP1 was significantly up-regulated in breast cancer tissues compared with adjacent normal tissues (82 of 128, 64%). Over-expressed SHCBP1 was correlated with advanced clinical stage and poorer survival. Ablation of SHCBP1 inhibited the proliferation in vitro.

  7. This study gives novel insight into the role of SHCBP in cytokinesis completion.

  8. Knockdown of SHCBP1 induced cell cycle delay.

  9. The central region of SHCBP1 was found to bind to measles virus C protein, as well as the phosphoprotein, but the two viral proteins did not compete for SHCBP1 binding.

Mouse (Murine) SHC SH2-Domain Binding Protein 1 (SHCBP1) interaction partners

  1. These data suggest that despite the striking upregulation of Shcbp1 during T cell proliferation, loss of Shcbp1 does not directly affect T cell development, but regulates CD4(+) T cell effector function in vivo.

SHCBP1 profil antigène

Antigen Summary

May play a role in signaling pathways governing cellular proliferation, cell growth and differentiation. May be a component of a novel signaling pathway downstream of Shc (By similarity).

Gene names and symbols associated with SHCBP1

  • SHC binding and spindle associated 1 (SHCBP1) anticorps
  • Shc SH2-domain binding protein 1 (Shcbp1) anticorps
  • mPAL anticorps
  • PAL anticorps

Protein level used designations for SHCBP1

SHC SH2 domain-binding protein 1 , SHC-binding protein , protein expressed in activated lymphocytes

79801 Homo sapiens
20419 Mus musculus
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