anti-SLAM Family Member 7 (SLAMF7) Anticorps

Mediates NK cell activation through a SH2D1A-independent extracellular signal-regulated ERK-mediated pathway. De plus, nous expédions SLAM Family Member 7 Protéines (25) et SLAM Family Member 7 Kits (8) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
SLAMF7 364049  
SLAMF7 57823 Q9NQ25
SLAMF7 75345 Q8BHK6
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Top anti-SLAM Family Member 7 Anticorps sur anticorps-enligne.fr

Showing 10 out of 93 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Livraison Prix Détails
Humain Lapin Inconjugué WB Western blot analysis of CD319 expression in A549 (A), SKOV3 (B), mouse spleen (C), mouse lung (D), rat testis (E) whole cell lysates. 200 μL 13 to 14 Days
$487.50
Détails
Humain Souris Inconjugué ELISA, FACS, IHC, WB Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng) Western blot analysis using CD319 mAb against human CD319 (AA: extra 23-226) recombinant protein. (Expected MW is 48.3 kDa) 0.1 mg 3 to 4 Days
$430.10
Détails
Humain Lapin Inconjugué WB Western blot analysis in NCI-H460 cell line lysates (35ug/lane). 400 μL 2 to 3 Days
$515.63
Détails
Humain Lapin Inconjugué ICC, IHC, WB Figure. Western Blot; Sample: Recombinant protein. Figure.DAB staining on IHC-P. Samples: Human Tissue 100 μg 13 to 16 Days
$350.00
Détails
Humain Souris Inconjugué FACS, IP 0.1 mg 3 to 4 Days
$289.88
Détails
Humain Lapin Inconjugué IF (p), IHC (p), WB Formalin-fixed and paraffin embedded mouse stomach labeled with Anti-SLAMF7/CD319/CS1 Polyclonal Antibody, Unconjugated (ABIN741825) at 1:200 followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded mouse intestine labeled with Anti-SLAMF7/CD319/CS1 Polyclonal Antibody, Unconjugated (ABIN741825) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL 3 to 7 Days
$329.45
Détails
Souris Lapin Inconjugué ELISA   100 μL 14 to 16 Days
$312.53
Détails
Souris Lapin Inconjugué ELISA   100 μL 14 to 16 Days
$183.12
Détails
Souris Lapin Inconjugué ELISA, WB   100 μL 14 to 16 Days
$247.82
Détails
Humain Lapin Inconjugué IHC (p), WB Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human lymph node with SLAMF7 polyclonal antibody  shows strong cytoplasmic positivity in germinal center cells and non-germinal center cells. Western Blot analysis with SLAMF7 polyclonal antibody . Lane 1: Human cell line RT-4 Lane 2: Human cell line U-251MG Lane 3: Human plasma 100 μL 11 to 12 Days
$577.33
Détails

anti-SLAM Family Member 7 Anticorps mieux référencés

  1. Human Monoclonal SLAMF7 Primary Antibody pour FACS, IP - ABIN2479975 : Yamate, Ransom: Effects of altered gliogenesis on activity-dependent K+ accumulation in the developing rat optic nerve. dans Brain research 1985 (PubMed)
    Show all 3 Pubmed References

  2. Human Monoclonal SLAMF7 Primary Antibody pour FACS - ABIN2479977 : Bouchon, Cella, Grierson, Cohen, Colonna: Activation of NK cell-mediated cytotoxicity by a SAP-independent receptor of the CD2 family. dans Journal of immunology (Baltimore, Md. : 1950) 2001 (PubMed)
    Show all 3 Pubmed References

  3. Human Monoclonal SLAMF7 Primary Antibody pour FACS - ABIN2479979 : Tassi, Colonna: The cytotoxicity receptor CRACC (CS-1) recruits EAT-2 and activates the PI3K and phospholipase Cgamma signaling pathways in human NK cells. dans Journal of immunology (Baltimore, Md. : 1950) 2005 (PubMed)
    Show all 3 Pubmed References

  4. Human Polyclonal SLAMF7 Primary Antibody pour IF (p) - ABIN915407 : Maekawa, Osawa, Izumi, Nagao, Takano, Okada, Tachi, Teramoto, Kawamura, Horiuchi, Saga, Kato, Yamamura, Watanabe, Kobayashi, Kobayashi, Sato, Hashimoto, Suzu, Kimura: Myeloproliferative leukemia protein activation directly induces fibrocyte differentiation to cause myelofibrosis. dans Leukemia 2017 (PubMed)

  5. Human Monoclonal SLAMF7 Primary Antibody pour FACS - ABIN4897032 : Lisenko, Schönland, Jauch, Andrulis, Röcken, Ho, Goldschmidt, Hegenbart, Hundemer: Flow cytometry-based characterization of underlying clonal B and plasma cells in patients with light chain amyloidosis. dans Cancer medicine 2016 (PubMed)

  6. Human Monoclonal SLAMF7 Primary Antibody pour FACS - ABIN4897035 : Tai, Dillon, Song, Leiba, Li, Burger, Lee, Podar, Hideshima, Rice, van Abbema, Jesaitis, Caras, Law, Weller, Xie, Richardson, Munshi, Mathiot, Avet-Loiseau, Afar, Anderson: Anti-CS1 humanized monoclonal antibody HuLuc63 inhibits myeloma cell adhesion and induces antibody-dependent cellular cytotoxicity in the bone marrow milieu. dans Blood 2008 (PubMed)

  7. Human Monoclonal SLAMF7 Primary Antibody pour CyTOF, FACS - ABIN4900006 : Hislop, Palendira, Leese, Arkwright, Rohrlich, Tangye, Gaspar, Lankester, Moretta, Rickinson: Impaired Epstein-Barr virus-specific CD8+ T-cell function in X-linked lymphoproliferative disease is restricted to SLAM family-positive B-cell targets. dans Blood 2010 (PubMed)

  8. Mouse (Murine) Monoclonal SLAMF7 Primary Antibody pour CyTOF, FACS - ABIN4899658 : Yigit, Halibozek, Chen, OKeeffe, Arnason, Avigan, Gattei, Bhan, Cen, Longnecker, Chiorazzi, Wang, Engel, Terhorst: A combination of an anti-SLAMF6 antibody and ibrutinib efficiently abrogates expansion of chronic lymphocytic leukemia cells. dans Oncotarget 2016 (PubMed)

Plus d’anticorps contre SLAM Family Member 7 partenaires d’interaction

Cow (Bovine) SLAM Family Member 7 (SLAMF7) interaction partners

  1. The SLAMF-AS2 isoforms are expressed the lowest levels among the three transcripts in both normal and infected mammary tissues.

Human SLAM Family Member 7 (SLAMF7) interaction partners

  1. Down-regulation of SLAMF7 and up-regulation of TREM1 occur in primary and metastatic stage IV colorectal cancer tissues.

  2. cancer cell expression of SLAMF7 is not required for phagocytosis and, in contrast to CD47 expression, should not be used as selection criterion for CD47-targeted therapy.

  3. Memory CD8+ T cells from SLE patients displayed decreased amounts of SLAMF7, a surface receptor that characterizes effector CD8+ T cells. Ligation of SLAMF7 increased CD8+ T cell degranulation capacity and the percentage of IFNgamma-producing cells in response to antigen challenge in SLE patients and healthy controls. SLAMF7 engagement promoted cytotoxic lysis of target cells in response to stimulation with viral antig...

  4. phagocytosis of haematopoietic tumour cells during SIRPalpha-CD47 blockade was strictly dependent on SLAM family receptors in vitro and in vivo; in both mouse and human cells, this function required a single SLAM family member, SLAMF7 (also known as CRACC, CS1, CD319), expressed on macrophages and tumour cell targets

  5. Cohort statistics revealed a significant increase of circulating sSLAMF7 in multiple myeloma patients versus normal controls

  6. Blimp-1 regulates the transcription of CS1 gene in NK and B cell lines from multiple myeloma and diffuse large B cell lymphoma patients.

  7. SLAMF7-triggered inhibition is mediated by a mechanism involving Src kinases, CD45, and SHIP-1 that is defective in MM cells

  8. Our data highlight the therapeutic potential of targeting CD319 in rheumatoid arthritis

  9. SLAMF7 plays an inhibitory role in human monocytes to control proinflammatory immune responses.

  10. These results suggest a role for CD319 and CD229 in the systemic lupus erythematosus disease process.

  11. These data suggest an involvement of CRACC-mediated NK cell activation in periodontal tissue destruction and point to a plausible distinction in the pathobiology of aggressive and chronic periodontitis.

  12. altered expression of splice variants of CS1 and 2B4 that mediate differential signalling in PBMC from patients with SLE.

  13. Data show that pair-wise ligations of 2B4 with DNAM-1 and/or NKG2D lead to increased effector functions of primary CD4(+)CD28(-) T cells to suboptimal levels of anti-CD3 stimulation.

  14. CS1-L and CS1-S may differentially regulate human NK cell functions

  15. blocking the engagement of 2B4, NTB-A and CRACC has no effect on the proliferation or development of the cytotoxic potential of NK cells but triggering by their physiological ligands on MHC class I-negative target cells induces potent NK cell cytotoxicity

  16. CS1 may play a role in the regulation of B lymphocyte proliferation during immune responses

  17. CS1 was expressed at adhesion-promoting uropod membranes of polarized Multiple Myeloma cells, andis required for MM cell adhesion to bone marrow stromal cells

  18. 2B4, NTB-A and CRACC have roles in the regulation of Natural Killer cell function [review]

  19. HuLuc63 eliminates myeloma cells, at least in part, via NK-mediated ADCC and shows the therapeutic potential of targeting CS1 with HuLuc63 for the treatment of multiple myeloma.

Mouse (Murine) SLAM Family Member 7 (SLAMF7) interaction partners

  1. phagocytosis of haematopoietic tumour cells during SIRPalpha-CD47 blockade was strictly dependent on SLAM family receptors in vitro and in vivo; in both mouse and human cells, this function required a single SLAM family member, SLAMF7 (also known as CRACC, CS1, CD319), expressed on macrophages and tumour cell targets

  2. CRACC-CRACC interaction between Kupffer and NK cells contributes to poly I:C/D-GalN induced hepatitis.

  3. 2B4, NTB-A and CRACC have roles in the regulation of Natural Killer cell function [review]

  4. CRACC was a critical positive regulator of NK cell function mediated by EAT-2.

SLAM Family Member 7 (SLAMF7) profil antigène

Profil protéine

Mediates NK cell activation through a SH2D1A-independent extracellular signal-regulated ERK-mediated pathway. May play a role in lymphocyte adhesion (By similarity).

Gene names and symbols associated with SLAMF7

  • SLAM family member 7 (Slamf7) anticorps
  • SLAM family member 7 (SLAMF7) anticorps
  • SLAM family member 7 (slaf7) anticorps
  • 19A anticorps
  • 19A24 anticorps
  • 4930560D03Rik anticorps
  • CD319 anticorps
  • CRACC anticorps
  • CS1 anticorps
  • RGD1560190 anticorps
  • slaf7 anticorps
  • SLAMF7 anticorps

Protein level used designations for SLAMF7

SLAM family member 7 , SLAM family member 7 variant 1 , SLAM family member 7 variant 2 , 19A24 protein , CD2 subset 1 , CD2-like receptor activating cytotoxic cells , CD2-like receptor-activating cytotoxic cells , membrane protein FOAP-12 , novel LY9 (lymphocyte antigen 9) like protein , protein 19A , leukocyte cell-surface antigen , novel Ly9

GENE ID SPECIES
364049 Rattus norvegicus
609992 Canis lupus familiaris
746961 Pan troglodytes
790164 Bos taurus
100196231 Salmo salar
57823 Homo sapiens
75345 Mus musculus
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