anti-SP110 Nuclear Body Protein (SP110) Anticorps

The nuclear body is a multiprotein complex that may have a role in the regulation of gene transcription. De plus, nous expédions SP110 Nuclear Body Protein Protéines (3) et et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
SP110 3431 Q9HB58
SP110 109032 Q8BVK9
SP110 301570 Q3KRF1
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Top anti-SP110 Nuclear Body Protein Anticorps sur anticorps-enligne.fr

Showing 10 out of 70 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Chien Lapin Inconjugué WB WB Suggested Anti-SAntibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:1562500  Positive Control:  MCF7 cell lysate Sis strongly supported by BioGPS gene expression data to be expressed in Human MCF7 cells 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Cheval Lapin Inconjugué WB WB Suggested Anti-SAntibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:62500  Positive Control:  HepG2 cell lysate 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Humain Lapin Inconjugué WB WB Suggested Anti-SAntibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  HT1080 cell lysate There is BioGPS gene expression data showing that Sis expressed in HT1080 Host:  Rabbit  Target Name:  S Sample Type:  Human MCF7  Antibody Dilution:  1.0ug/ml  Sis strongly supported by BioGPS gene expression data to be expressed in Human MCF7 cells 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Humain Souris Inconjugué IP, ELISA, WB 100 μg Connectez-vous pour afficher 7 to 9 Days
$537.17
Détails
Humain Souris Inconjugué ELISA, IF, WB Immunofluorescence of monoclonal antibody to SP110 on HeLa cell (antibody concentration 10 µg/mL). SP110 monoclonal antibody (M03), clone 2G10 Western Blot analysis of SP110 expression in Hela NE. 100 μg Connectez-vous pour afficher 8 to 11 Days
$461.00
Détails
Humain Lapin Inconjugué WB 100 μL Connectez-vous pour afficher 7 to 9 Days
$507.83
Détails
Chien Lapin Inconjugué WB 50 μg Connectez-vous pour afficher 7 to 9 Days
$551.83
Détails
Humain Lapin Inconjugué WB 50 μg Connectez-vous pour afficher 7 to 9 Days
$551.83
Détails
Humain Lapin Inconjugué WB 50 μg Connectez-vous pour afficher 7 to 9 Days
$551.83
Détails
Humain Souris Inconjugué IF, ELISA, WB SP110 monoclonal antibody (M02), clone 6F11 Western Blot analysis of SP110 expression in Hela S3 NE . Immunofluorescence of monoclonal antibody to SP110 on HeLa cell. [antibody concentration 10 ug/ml] 100 μg Connectez-vous pour afficher 11 to 12 Days
$440.00
Détails

anti-SP110 Nuclear Body Protein Anticorps mieux référencés

  1. Human Polyclonal SP110 Primary Antibody pour IHC, ELISA - ABIN1002686 : Bloch, Nakajima, Gulick, Chiche, Orth, de La Monte, Bloch: Sp110 localizes to the PML-Sp100 nuclear body and may function as a nuclear hormone receptor transcriptional coactivator. dans Molecular and cellular biology 2000 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal SP110 Primary Antibody pour ELISA, WB - ABIN1002687 : Pan, Yan, Rojas, Shebzukhov, Zhou, Kobzik, Higgins, Daly, Bloom, Kramnik: Ipr1 gene mediates innate immunity to tuberculosis. dans Nature 2005 (PubMed)
    Show all 3 Pubmed References

Plus d’anticorps contre SP110 Nuclear Body Protein partenaires d’interaction

Cow (Bovine) SP110 Nuclear Body Protein (SP110) interaction partners

  1. SP110 as a novel susceptibility gene for Mycobacterium avium subspecies paratuberculosis infection in cattle.

Horse (Equine) SP110 Nuclear Body Protein (SP110) interaction partners

  1. Novel splice variants of SP110 in the horse have an activation effect on macrophages.

Human SP110 Nuclear Body Protein (SP110) interaction partners

  1. TNF-alpha (Montrer TNF Anticorps) -308G>A (rs1800629) showed no association with susceptibility to pulmonary tuberculosis and spinal tuberculosis patients in southern China.

  2. SP110 polymorphism is associated with tuberculosis.

  3. Data suggest that Sp110 is sumoylated, de-sumoylated, and then released from the promyelocytic leukemia (Montrer PML Anticorps) nuclear bodies in hepatocytes infected with HBV (hepatitis B virus); Sp110 differentially regulates several direct target genes of HBx, a viral co-factor; these mechanisms may be involved in evasion of host immune response by HBV. (Sp110 = Speckled 110 kDa; HBx = hepatitis B virus protein X)

  4. Using mouse models and genetic characteristics of human patients the role of SP110b was studied to determine its role in controlling host immunity and susceptibility to TB by modulating nuclear factor-kappaB (NF-kappaB (Montrer NFKB1 Anticorps)) activity resulting in down regulation of TNF-alpha (Montrer TNF Anticorps) production and upregulation of NF-kappaB (Montrer NFKB1 Anticorps)-induced antipoptotic gene expression suppressing IFN-gamma (Montrer IFNG Anticorps)-mediated monocyte and/or macrophage cell death.

  5. The results indicated that both the heterozygous genotype GC and homozygous genotype CC in rs3809849 in MYBBP1A (Montrer MYBBP1A Anticorps) had significant effects on the risk of pulmonary tuberculosis, and heterozygous genotype CT in rs9061 in SP110 also had similar effects.

  6. Results show that SP110 variants were associated with increased susceptibility to both pulmonary and extra-pulmonary tuberculosis in the Vietnamese patients. Those variants may influence macrophage signaling responses and apoptosis during the infection.

  7. Study suggests that a combination of SP110 and MYBBP1A gene polymorphisms may serve as a novel marker for identifying the risk of developing TB in the Chinese Han population.

  8. Several SNPs in Sp110 are risk factors for susceptibility to tuberculosis in Chongqing Han People.

  9. In a pooled analysis of 10,624 cases of tuberculosis, there was not a significant association between polymorphisms in the SP110 gene and disease susceptibility. [Meta-analysis]

  10. Genotyped 20 SNPs located in the SP110 gene, for the first time in a South East Asian cohort from Indonesia.Our study did not reveal any statistically significant associations between SP110 SNPs and pulmonary TB.

Mouse (Murine) SP110 Nuclear Body Protein (SP110) interaction partners

  1. mechanistic studies revealed that an arginine/lysine-rich element within the DNA-binding domain (SAND domain) is critical for Ipr1 binding to the importin protein receptor NPI-1 (Montrer KPNA1 Anticorps), demonstrating that this element plays an essential role in mediating the nuclear localization of Ipr1 protein

  2. Using mouse models and genetic characteristics of human patients the role of SP110b was studied to determine its role in controlling host immunity and susceptibility to TB by modulating nuclear factor-kappaB (NF-kappaB (Montrer NFKB1 Anticorps)) activity resulting in down regulation of TNF-alpha (Montrer TNF Anticorps) production and upregulation of NF-kappaB (Montrer NFKB1 Anticorps)-induced antipoptotic gene expression suppressing IFN-gamma (Montrer IFNG Anticorps)-mediated monocyte and/or macrophage cell death.

  3. These findings not only reveal the transcriptional basis of Sp110-mediated macrophage resistance to Mtb (Montrer NCAPG2 Anticorps), but also suggest potential regulatory roles for Sp110 related to inflammatory responses, miRNA profiles, and the intracellular growth of Mtb (Montrer NCAPG2 Anticorps).

  4. Ipr1 might be involved in apoptosis pathway via MYBBP1A (Montrer MYBBP1A Anticorps).

  5. identification and analysis of the genes Sp100 (Montrer SP100 Anticorps), Csprs, and Ifi75 in two members of the genus Mus (Montrer TRPV6 Anticorps), M. musculus and M. caroli

  6. data indicate that the Ipr1 gene product might have a previously undocumented function in integrating signals generated by intracellular pathogens with mechanisms controlling innate immunity, cell death and pathogenesis

SP110 Nuclear Body Protein (SP110) profil antigène

Profil protéine

The nuclear body is a multiprotein complex that may have a role in the regulation of gene transcription. This gene is a member of the SP100/SP140 family of nuclear body proteins and encodes a leukocyte-specific nuclear body component. The protein can function as an activator of gene transcription and may serve as a nuclear hormone receptor coactivator. In addition, it has been suggested that the protein may play a role in ribosome biogenesis and in the induction of myeloid cell differentiation. Alternative splicing has been observed for this gene and three transcript variants, encoding distinct isoforms, have been identified.

Gene names and symbols associated with SP110

  • SP110 nuclear body protein (SP110) anticorps
  • Sp110 nuclear body protein (Sp110) anticorps
  • SP110 nuclear body protein (Sp110) anticorps
  • 52kDa anticorps
  • 5031415C07Rik anticorps
  • 5830484A20Rik anticorps
  • ENSMUSG00000075603 anticorps
  • IFI41 anticorps
  • Ifi75 anticorps
  • Ipr1 anticorps
  • SP110 anticorps
  • VODI anticorps

Protein level used designations for SP110

SP110 nuclear body protein , sp110 nuclear body protein-like , interferon-induced protein 41, 30kD , interferon-induced protein 41/75 , interferon-induced protein 75, 52kD , phosphoprotein 41 , phosphoprotein 75 , sp110 nuclear body protein , speckled 110 kDa , transcriptional coactivator Sp110 , intracellular pathogen resistance 1 , intracellular pathogen resistance protein 1

GENE ID SPECIES
470728 Pan troglodytes
515204 Bos taurus
100056977 Equus caballus
100391349 Callithrix jacchus
100452909 Pongo abelii
100585660 Nomascus leucogenys
3431 Homo sapiens
100686387 Canis lupus familiaris
109032 Mus musculus
301570 Rattus norvegicus
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