SRY (Sex Determining Region Y)-Box 5 (SOX5) Kits ELISA

SOX5 encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. De plus, nous expédions SOX5 Anticorps (50) et SOX5 Protéines (5) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
SOX5 6660 P35711
Anti-Souris SOX5 SOX5 20678 P35710
Anti-Rat SOX5 SOX5 140587  
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Top SOX5 Kits ELISA sur

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Catalogue No. Reactivité Sensibilité Gamme Images Quantité Fournisseur Livraison Prix Détails
Humain 19.5 pg/mL 78-5000 pg/mL Typical standard curve 96 Tests Connectez-vous pour afficher 15 to 18 Days
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  10 reactions Connectez-vous pour afficher 4 to 6 Days

Plus Kits ELISA pour SOX5 partenaires d'interaction

Human SRY (Sex Determining Region Y)-Box 5 (SOX5) interaction partners

  1. First reported meta-analysis of genome-wide association study for chronic back pain (CBP) in adults of European ancestry identified novel genetic associations with CBP at SOX5, CCDC26/GSDMC, and DCC.[meta-analysis]

  2. Sox5 is a previously unrecognized regulator of beta-cell gene expression and secretory function

  3. SOX5 overexpression increased Kruppel-like factor 4 (KLF4) gene expression, which was decreased by SOX5 silencing. KLF4 knockdown abrogated the suppressive effect of SOX5 overexpression on osteogenic differentiation of hMSCs.

  4. Results show that SOX5 expression levels is increased in the synovium of patients with rheumatoid arthritis (RA). Its overexpression regulates the expression of RANKL in RA synovial fibroblasts.

  5. SOX5, candidate gene, associated with clinical features of Depression (e.g., earlier age at onset and recurrent and more severe forms of Depression). Gene expression patterns in the prefrontal and anterior cingulate cortex most closely matched the genetic findings.

  6. SOX5 promoted epithelial-mesenchymal transition (EMT) by regulation of Snail.

  7. Short-SOX5 regulates transcription of human SPAG16L gene via directly binding to the promoter of SPAG16L.

  8. results suggest that lnc-Sox5, which was stabilized by HuR, could regulate carcinogenesis of tongue cancer and may serve as a predicted target for tongue carcinoma therapies

  9. Collectively, these findings indicate that SOX5 is a novel candidate gene for Alzheimer's disease(AD) with an important role in neuronal function. The genetic findings warrant further studies to identify and characterize SOX5 variants that confer risk for AD, amyotrophic lateral sclerosis and intellectual disability.

  10. The results of the present study suggest a role for SOX5 in the molecular pathogenesis of FL.

  11. SOX5 has a strong inhibitory effect on MITF expression and seems to have a decisive clinical impact on melanoma during tumor progression.

  12. Our results indicate for the first time that SOX5 is a novel regulator of epithelial-mesenchymal transition in hepatocellular carcinoma

  13. Sox5-PAX5 fusion transcript is associated with B-cell precursor acute lymphoblastic leukemia.

  14. Identified two new splice variants of SOX5 in human B cells, encoding the known L-SOX5B isoform and a new shorter isoform L-SOX5F. SOX5 limits the proliferative capacity of human primary B lymphocytes and potentially affects the differentiation of human B cells during the germinal center responses.

  15. High Sox5 expression is associated with pituitary tumor.

  16. detection of SOX5 polymorphism in nonobstructive azoospermia contributing to predicting males at high risk of disease in Han Chinese population

  17. Sox5 and Sox9 cause a significant increase in transactivation of the Catsper1 promoter.

  18. depletion of Sox5 in breast cancer cells caused a dramatic decrease in Twist1 and chromosome immunoprecipitation assay showed that Sox5 can bind directly to the Twist1 promoter, suggesting that Sox5 transactivates Twist1 expression

  19. Sox5 regulates the proliferation of malignant B cells.

Mouse (Murine) SRY (Sex Determining Region Y)-Box 5 (SOX5) interaction partners

  1. Data show that SRY-box containing gene 5 protein (Sox5) can physically bind to the collapsin response mediator protein 5 (CRMP5) promoter DNA.

  2. the novel role of Tgfb2, Fbxl18, and Tle3 in formation of Sox5, Sox6, and Sox9 dependent tissues.

  3. Low SOX5 expression is associated with Glioma.

  4. Study revealed that Sox5 and Sox6 prevent oligodendroglial differentiation, thus ensuring that the progenitor cells first reach their proper destination and only then lose their migratory capacity

  5. This study demonstrated that Sox13 functionally complements the related Sox5 and Sox6 as important developmental modulators in mouse spinal cord oligodendrocytes.

  6. Results show that Sox9, Sox5, and Sox13 transcription factors are expressed in postnatal testis and may regulate multiple functions such as steroidogenesis and spermatogenesis.

  7. Results suggest that L-Sox5 protein expression may diminish along with the progress of chondrogenic differentiation. L-Sox5 may act as a negative regulator if expressed aberrantly at least in part by regulating the critical fate of chondrogenesis.

  8. T cell-specific Sox5-deficient mice exhibit impaired Th17 cell differentiation and are resistant to experimental autoimmune encephalomyelitis and delayed-type hypersensitivity.

  9. Sox5 regulates the proliferation of malignant B cells.

  10. L-Sox5 and Sox6 proteins enhance chondrogenic miR-140 microRNA expression by strengthening dimeric Sox9 activity

  11. MiR-194 regulates chondrogenic differentiation of adipose-derived stem cells by targeting Sox5

  12. Genetic variation in the transcription factor SOX5 is associated with COPD susceptibility

  13. SPAG6 is a S-SOX5 target gene, indicating a key role for S-SOX5 in the formation and function of motile cilia.

  14. These data suggest that synovial joint morphogenesis relies on essential roles for Sox5/6 in promoting both growth plate and articular chondrocyte differentiation.

  15. transcription factor SOX-5 plays a significant role in the expression of the skeletal muscle L-type Ca(2+) channel alpha(1S)

  16. Sox5 is required for notochord extracellular matrix sheath formation, notochord cell survival and formation of nuclei pulposi

  17. The SOX trio (SOX5, 6, 9) induced chondrocyte differentiation in all cell types tested, including nonchondrogenic types, regardless of culture system used. The SOX trio suppressed hypertrophic and osteogenic differentiation at the same time.

  18. The data of this study indicate that SOX5 controls the timing of critical fate decisions during corticofugal neuron production and thus subtype-specific differentiation and neocortical neuron diversity.

  19. Generation of mice harboring a Sox5 conditional null allele is reported.

  20. This study uncovers critical cis-acting elements and transcription factors driving Agc1 expression in cartilage and increases understanding of the mode of action of the chondrogenic Sox trio.

Cow (Bovine) SRY (Sex Determining Region Y)-Box 5 (SOX5) interaction partners

  1. These results demonstrate that C/T missense mutation within the SOX5 gene is involved in bull sperm quality.

Xenopus laevis SRY (Sex Determining Region Y)-Box 5 (SOX5) interaction partners

  1. The inhibitory function of Meox2 and the pro-myogenic function of Sox5 were confirmed during Xenopus normal development by the use of translation-blocking oligomorpholinos and dexamethasone inducible chimeric Sox5 and Meox2 proteins.

  2. show that Sox5 is essential for activation of BMP target genes in embryos and explants, that it physically interacts with BMP R-Smads

Zebrafish SRY (Sex Determining Region Y)-Box 5 (SOX5) interaction partners

  1. findings reveal surprising diversity in even the mode of the interactions between Sox5 and Sox10 governing specification of pigment cell types in medaka and zebrafish, and suggest that this is related to the evolution of a fourth pigment cell type

SOX5 profil antigène

Antigen Summary

This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. The encoded protein may play a role in chondrogenesis. A pseudogene of this gene is located on chromosome 8. Multiple transcript variants encoding distinct isoforms have been identified for this gene.

Gene names and symbols associated with SOX5

  • SRY-box 5 (SOX5) anticorps
  • SRY-box 5 (sox5) anticorps
  • SRY (sex determining region Y)-box 5 (Sox5) anticorps
  • SRY box 5 (Sox5) anticorps
  • SRY-box 5 S homeolog (sox5.S) anticorps
  • SRY-box 5 (Sox5) anticorps
  • SRY (sex determining region Y)-box 5 (sox5) anticorps
  • A730017D01Rik anticorps
  • AI528773 anticorps
  • id:ibd5067 anticorps
  • l-sox5 anticorps
  • sb:eu456 anticorps
  • si:dkey-215a8.1 anticorps
  • Sox5l1 anticorps
  • XSox-5 anticorps
  • xSox5 anticorps

Protein level used designations for SOX5

transcription factor SOX-5 , transcription factor LSox5-I , SRY (sex determining region Y)-box 5 , Transcription factor Sox-5 , SRY-box containing gene 5 , SRY-box containing gene 5-like 1 , SRY-box 5 , SRY-related HMG-box 5 protein , sox5b

6660 Homo sapiens
418195 Gallus gallus
100038209 Xenopus (Silurana) tropicalis
20678 Mus musculus
140587 Rattus norvegicus
533829 Bos taurus
100381154 Xenopus laevis
100715697 Cavia porcellus
100627965 Sus scrofa
100348988 Oryctolagus cuniculus
486635 Canis lupus familiaris
100064442 Equus caballus
567413 Danio rerio
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