Use your antibodies-online credentials, if available.
Il n’y a pas de produits dans votre liste de comparaison.
Votre panier est vide.
Sclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. De plus, nous expédions Sclerostin Anticorps (127) et Sclerostin Protéines (18) et beaucoup plus de produits pour cette protéine.
Showing 10 out of 63 products:
Human Sclerostin Kit ELISA pour Sandwich ELISA - ABIN457071
Cidem, Usta, Karacan, Kucuk, Uludag, Gun: Effects of sex steroids on serum sclerostin levels during the menstrual cycle. dans Gynecologic and obstetric investigation 2013
Show all 5 Pubmed References
Human Sclerostin Kit ELISA pour Sandwich ELISA - ABIN415155
Brabnikova Maresova, Pavelka, Stepan: Acute effects of glucocorticoids on serum markers of osteoclasts, osteoblasts, and osteocytes. dans Calcified tissue international 2013
Show all 3 Pubmed References
Rat (Rattus) Sclerostin Kit ELISA pour Sandwich ELISA - ABIN416496
Kim, Lee, Jo, Song, Lim, Park, Bonewald, Kim: Exendin-4 increases bone mineral density in type 2 diabetic OLETF rats potentially through the down-regulation of SOST/sclerostin in osteocytes. dans Life sciences 2013
Show all 2 Pubmed References
Mouse (Murine) Sclerostin Kit ELISA pour Sandwich ELISA - ABIN426039
Yorgan, Peters, Jeschke, Benisch, Jakob, Amling, Schinke: The Anti-Osteoanabolic Function of Sclerostin Is Blunted in Mice Carrying a High Bone Mass Mutation of Lrp5. dans Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2015
Show all 2 Pubmed References
Rat (Rattus) Sclerostin Kit ELISA pour Sandwich ELISA - ABIN585201
Ferreira, Ferrari, Neves, Cavallari, Dominguez, Dos Reis, Graciolli, Oliveira, Liu, Sabbagh, Jorgetti, Schiavi, Moysés: Effects of dietary phosphate on adynamic bone disease in rats with chronic kidney disease--role of sclerostin? dans PLoS ONE 2013
Positivity of RANKL (Montrer TNFSF11 Kits ELISA) and anti-CCP2 (Montrer AGBL2 Kits ELISA) yielded significant risk for progression with negativity for both as reference. No single nucleotide polymorphism encoding TNFSF11 (Montrer TNFSF11 Kits ELISA) or SOST was associated with increased concentrations of the factors.
Osterix (Montrer SP7 Kits ELISA) and RUNX2 (Montrer RUNX2 Kits ELISA) are transcriptional regulators of sclerostin in human bone
Sclerostin But Not Dickkopf-1 (Montrer DKK1 Kits ELISA) has roles in increasing prevalence of osteoporotic fracture and lower bone mineral density in postmenopausal Korean women
An association was found between rs851054 of the SOST promoter and the fracture rate during childhood osteogenesis imperfecta (Montrer COL1A2 Kits ELISA).
High serum levels of sclerostin and Dkk-1 (Montrer DKK1 Kits ELISA) are associated with acute ischaemic stroke
The increased expression of sclerostin in the liver and the association with histologic cholangitis may explain the high serum levels of this protein in patients with primary biliary cirrhosis.
SOST silencing promotes the proliferation, invasion and migration, and decreases the apoptosis of human retinoblastoma cells by activating the Wnt (Montrer WNT2 Kits ELISA)/beta-catenin (Montrer CTNNB1 Kits ELISA) signaling pathway.
Sclerostin concentrations in serum significantly decreased and IGF-I (Montrer IGF1 Kits ELISA) significantly increased after 12months of resistance training or JUMP.
observed an association between sclerostin levels with fasting insulin (Montrer INS Kits ELISA) levels and homoeostatic model assessment-insulin (Montrer INS Kits ELISA) resistance, but there was no clear association with type 2 diabetes risk.
Sclerostin levels in KTR are normal and influenced more by bone turnover than by eGFR (Montrer EGFR Kits ELISA). Its involvement with other hormones of mineral homeostasis (FGF23 (Montrer FGF23 Kits ELISA)/Klotho (Montrer KL Kits ELISA) and Vitamin D) is part of the sophisticated cross-talk between bone and the kidney
These results show that osteocytes and/or osteoblasts secrete factors regulating beige (Montrer LYST Kits ELISA) adipogenesis, at least in part, through the Wnt (Montrer WNT2 Kits ELISA)-signaling inhibitor sclerostin.
In vivo muCT analysis of cortical bone at age 1 and 3 months confirmed increased thickness in Sost-/-mice, but revealed no cortical abnormalities in single Gja1 (Montrer GJA1 Kits ELISA)+/-or Sost+/-mice
loss of BMP signaling specifically in osteocytes dramatically increases bone mass presumably through simultaneous inhibition of RANKL (Montrer TNFSF11 Kits ELISA) and SOST, leading to osteoclast inhibition and Wnt (Montrer WNT2 Kits ELISA) activation together.
humanized Multiple Myeloma xenograft mouse model bearing human MM cells (NOD-SCID.CB17 male mice injected intravenously with 2.5 million of MM1 (Montrer PFDN5 Kits ELISA).S-Luc-GFP cells) demonstrated significantly higher concentrations of mouse-derived sclerostin, suggesting a microenvironmental source of sclerostin.
Protection From Glucocorticoid-Induced Osteoporosis by Anti-Catabolic Signaling in the Absence of Sost/Sclerostin
Osteocyte-derived molecule sclerostin drives bone marrow adipogenesis.
complete absence of sclerostin has only minor effects on chronic kidney disease-induced bone loss in mice.
In mice, sclerostin deficiency hastened reparative dentinogenesis after pulp injury, suggesting that the inhibition of sclerostin may constitute a promising therapeutic strategy for improving the healing of damaged pulps.
These data suggest that sclerostin plays an important role in the bone remodeling of tooth movement.
Sclerostin inhibits angiotensin II-induced aortic aneurysm and atherosclerosis via wnt (Montrer WNT2 Kits ELISA) signaling pathway inhibition.
Sclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Loss-of-function mutations in this gene are associated with an autosomal-recessive disorder, sclerosteosis, which causes progressive bone overgrowth. A deletion downstream of this gene, which causes reduced sclerostin expression, is associated with a milder form of the disorder called van Buchem disease.