Sestrin 1 (SESN1) Kits ELISA

SESN1 encodes a member of the sestrin family. De plus, nous expédions Sestrin 1 Anticorps (78) et Sestrin 1 Protéines (7) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
SESN1 27244 Q9Y6P5
SESN1 140742 P58006
Anti-Rat SESN1 SESN1 294518  
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Top Sestrin 1 Kits ELISA sur

Showing 3 out of 9 products:

Catalogue No. Reactivité Sensibilité Gamme Images Quantité Livraison Prix Détails
Souris 0.058 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests 13 to 16 Days
Humain 0.33 ng/mL 0.156-10 ng/mL   96 Tests 2 to 3 Days
Humain 0064 ng/mL 0.156 ng/mL - 10 ng/mL   96 Tests 15 to 17 Days

Plus Kits ELISA pour Sestrin 1 partenaires d'interaction

Zebrafish Sestrin 1 (SESN1) interaction partners

  1. identify SESN1 as an indispensable gene for vertebrate left-right asymmetry and a new player in mediating Nodal signaling

Human Sestrin 1 (SESN1) interaction partners

  1. identified new interactions between miR-200 and the oxidative stress response SESN proteins that affect anoikis resistance in human endometrial cancer cells.

  2. mRNA expression of SESN1 was upregulated in older men.

  3. Study shows that SESN1 mRNA, UHRF1BP11 mRNA and miRNA-377-3p levels are prognostically relevant in human papillomavirus-negative head and neck squamous cell carcinoma patients.

  4. The antitumor efficacy of pharmacological EZH2 inhibition depends on SESTRIN1, indicating that mTORC1 control is a critical function of EZH2 in lymphoma.

  5. Mass spectrometry analysis, western blot and surface plasmon resonance (SPR) of affinity purified sesn1 and sesn2 proteins confirmed their identity; biophysical characteristics were observed using circular dichroism (CD) showing that sesn1 and sesn2 have a predominant a-helical structure.

  6. this study shows that sestrin1 genetic ablation results in broad reconstitution of immune function in stressed T cells and enhanced vaccine responsiveness in old mice

  7. Rapamycin may prohibit sestrin1 downregulation through targeting mTORC2 in appeasing low shear stress induced EC oxidative apoptosis

  8. PA26 mutations are an infrequent cause of heterotaxia (situs inversus) in humans.

  9. results show that sestrins, a family of proteins whose expression is modulated by p53, are required for regeneration of peroxiredoxins containing Cys-SO(2)H

Mouse (Murine) Sestrin 1 (SESN1) interaction partners

  1. Sestrin 1 targets at the AMPK/mTORC1/autophagy pathway to inhibit cardiac hypertrophy by interaction with AMPK which is responsible for autophagy regulation. Taken together, our data indicate that Sestrin 1 regulates AMPK/mTORC1/autophagy axis to attenuate cardiac hypertrophy.

  2. Study found that Sestrins (1,2 and 3) can inhibit mTORC1 signaling in the absence of AMPK or TSC2. Surprisingly, when coexpressed with a GTP-bound constitutively active form of RagB (RagBQ99L), Sestrins potentiate mTORC1 signaling in the absence of amino acids.

  3. The enhanced tumor susceptibility of p53+/- mice has made them one of several transgenic mouse models that are being considered as substitutes for standard 2-year rodent carcinogenicity assays.

  4. Sestrin1 and Sestrin2 therefore provide an important link between genotoxic stress, p53 and the mTOR signaling pathway.

Sestrin 1 (SESN1) profil antigène

Antigen Summary

This gene encodes a member of the sestrin family. Sestrins are induced by the p53 tumor suppressor protein and play a role in the cellular response to DNA damage and oxidative stress. The encoded protein mediates p53 inhibition of cell growth by activating AMP-activated protein kinase, which results in the inhibition of the mammalian target of rapamycin protein. The encoded protein also plays a critical role in antioxidant defense by regenerating overoxidized peroxiredoxins, and the expression of this gene is a potential marker for exposure to radiation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene names and symbols associated with Sestrin 1 (SESN1) Kits ELISA

  • sestrin 1 (SESN1) anticorps
  • sestrin 1 (sesn1) anticorps
  • sestrin 1 (Sesn1) anticorps
  • sestrin 1 L homeolog (sesn1.L) anticorps
  • 1110002G11Rik anticorps
  • AU044290 anticorps
  • Pa26 anticorps
  • SESN1 anticorps
  • sesn1-A anticorps
  • Sest1 anticorps
  • sestrin-1 anticorps
  • XPA26 anticorps
  • zgc:91970 anticorps

Protein level used designations for Sestrin 1 (SESN1) Kits ELISA

sestrin 1 , sestrin-1 , nuclear factor XPA26-T2 , p53 activated gene 26 , p53 regulated PA26 nuclear protein , p53 regulated Pa26 nuclear protein , p53-regulated protein PA26 , XPA26 , sestrin 1,nuclear factor XPA26-T2

421766 Gallus gallus
436933 Danio rerio
462922 Pan troglodytes
481956 Canis lupus familiaris
700232 Macaca mulatta
100170187 Xenopus (Silurana) tropicalis
100174188 Pongo abelii
100601789 Nomascus leucogenys
27244 Homo sapiens
140742 Mus musculus
294518 Rattus norvegicus
538226 Bos taurus
379559 Xenopus laevis
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