Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8) Kits ELISA

Sialic acid-binding immunoglobulin (Ig)-like lectins, or SIGLECs (e.g., CD33 (MIM 159590)), are a family of type 1 transmembrane proteins each having a unique expression pattern, mostly in hemopoietic cells. De plus, nous expédions SIGLEC8 Anticorps (76) et SIGLEC8 Protéines (7) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
SIGLEC8 27181 Q9NYZ4
SIGLEC8    
SIGLEC8    
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Top SIGLEC8 Kits ELISA sur anticorps-enligne.fr

Showing 8 out of 20 products:

Catalogue No. Reactivité Sensibilité Gamme Images Quantité Fournisseur Livraison Prix Détails
Humain 0.039 ng/mL 0.156-10 ng/mL Typical standard curve 96 Tests Connectez-vous pour afficher 15 to 18 Days
$910.56
Détails
Porc 0.094 ng/mL 0.156-10 ng/mL   96 Tests Connectez-vous pour afficher 12 to 14 Days
$715.00
Détails
Poulet 0.094 ng/mL 0.156-10 ng/mL   96 Tests Connectez-vous pour afficher 12 to 14 Days
$715.00
Détails
Lapin 37.5 pg/mL 62.5-4000 pg/mL   96 Tests Connectez-vous pour afficher 12 to 14 Days
$715.00
Détails
Singe
  96 Tests Connectez-vous pour afficher 12 to 14 Days
$616.00
Détails
Humain 0.058 ng/mL 0.156 ng/mL - 10 ng/mL   96 Tests Connectez-vous pour afficher 8 to 12 Days
$928.46
Détails
Mouton 0.469 ng/mL 0.781 ng/mL - 50 ng/mL   96 Tests Connectez-vous pour afficher 11 to 18 Days
$788.85
Détails
Humain < 0.058 ng/mL 0.156 ng/mL - 10 ng/mL   96 Tests Connectez-vous pour afficher 11 to 18 Days
$838.60
Détails

Plus Kits ELISA pour SIGLEC8 partenaires d'interaction

Human Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8) interaction partners

  1. In differentiating ,eosinophils, SIGLEC-8 messenger RNA and protein were markedly down-regulated in parallel with OLIG2 (Montrer OLIG2 Kits ELISA) by an OLIG2 (Montrer OLIG2 Kits ELISA) small interfering RNA or a short hairpin RNA. An E-box in the first intron was found to stimulate SIGLEC-8 gene transcription and to bind OLIG2 (Montrer OLIG2 Kits ELISA).

  2. miR (Montrer MLXIP Kits ELISA)-215 acts in concert with the host gene IARS2 to affect neuron migration and proliferation through the target gene SIGLEC-8.

  3. Our study suggested that intratumoral Siglec-8 expression was an independent prognostic factor for overall survival of patients with gastric cancer

  4. Ligands for Siglec-8 and Siglec-9 (Montrer SIGLEC9 Kits ELISA) may regulate the function of eosinophils, mast cells, neutrophils, and other cells in sinus mucosa.

  5. Inflammation results in up-regulation of immuneinhibitory Siglec-8 and Siglec-9 (Montrer SIGLEC9 Kits ELISA) sialoglycan ligands on human airways.

  6. Siglec-8 expression is sensitive to tiotropium and formoterol, indicating that it may be involved in COPD (Montrer ARCN1 Kits ELISA) pathogenesis and may influence COPD (Montrer ARCN1 Kits ELISA) phenotyping

  7. In activated eosinophils ligation of Siglec-8 leads to ROS (Montrer ROS1 Kits ELISA)-dependent enhancement of IL-5 (Montrer IL5 Kits ELISA)-induced ERK (Montrer EPHB2 Kits ELISA) phosphorylation, which results in a novel mode of biochemically regulated eosinophil cell death.

  8. Engagement of Siglec-8 on blood eosinophils results in caspase (Montrer CASP3 Kits ELISA)- and mitochondria-dependent apoptosis.

  9. Eosinophils primed by IL-33 (Montrer IL33 Kits ELISA) and/or IL-5 (Montrer IL5 Kits ELISA) in vivo would be expected to display enhanced susceptibility to undergoing Siglec-8-induced apoptosis.

  10. The Siglec-8 gene may be a susceptibility locus for asthma.

SIGLEC8 profil antigène

Antigen Summary

Sialic acid-binding immunoglobulin (Ig)-like lectins, or SIGLECs (e.g., CD33 (MIM 159590)), are a family of type 1 transmembrane proteins each having a unique expression pattern, mostly in hemopoietic cells. SIGLEC8 is a member of the CD33-like subgroup of SIGLECs, which are localized to 19q13.3-q13.4 and have 2 conserved cytoplasmic tyrosine-based motifs: an immunoreceptor tyrosine-based inhibitory motif, or ITIM (see MIM 604964), and a motif homologous to one identified in signaling lymphocyte activation molecule (SLAM\\\\; MIM 603492) that mediates an association with SLAM-associated protein (SAP\\\\; MIM 300490) (summarized by Foussias et al., 2000

Gene names and symbols associated with SIGLEC8

  • sialic acid binding Ig like lectin 8 (SIGLEC8) anticorps
  • sialic acid-binding Ig-like lectin 8 (LOC506364) anticorps
  • SAF2 anticorps
  • SIGLEC-8 anticorps
  • SIGLEC8 anticorps
  • SIGLEC8L anticorps

Protein level used designations for SIGLEC8

CDw329 , SAF-2 , sialic acid-binding Ig-like lectin 8 , sialoadhesin family member 2 , sialic acid binding Ig-like lectin 8

GENE ID SPECIES
27181 Homo sapiens
456249 Pan troglodytes
506364 Bos taurus
100595640 Nomascus leucogenys
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