anti-Signal Peptide Peptidase 3 (SPPL3) Anticorps

Intramembrane-cleaving aspartic protease (I-CLiP) that cleaves type II membrane signal peptides in the hydrophobic plane of the membrane.. De plus, nous expédions et et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
SPPL3 360822  
SPPL3 74585 Q9CUS9
SPPL3 121665 Q8TCT6
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Top anti-SPPL3 Anticorps sur anticorps-enligne.fr

Showing 10 out of 25 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Livraison Prix Détails
Humain Lapin Inconjugué EIA Western blot analysis of SPPL3(arrow) using rabbit polyclonal SPPL3 Antibody 0.4 mL 6 to 8 Days
$484.00
Détails
Poulet Lapin Inconjugué WB 100 μL 11 to 14 Days
$581.17
Détails
Humain Lapin Inconjugué WB Western blot analysis of SPPL3 using rabbit polyclonal SPPL3 Antibody using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the SPPL3 gene (Lane 2). 400 μL 2 to 3 Days
$515.63
Détails
Humain Lapin Alkaline Phosphatase (AP) ELISA, WB   200 μL 11 to 14 Days
$1,101.83
Détails
Humain Lapin Biotin ELISA, WB   200 μL 11 to 14 Days
$1,101.83
Détails
Humain Lapin PE ELISA, WB   200 μL 11 to 14 Days
$1,101.83
Détails
Humain Lapin FITC ELISA, WB   200 μL 11 to 14 Days
$1,101.83
Détails
Humain Lapin Inconjugué ELISA, WB   200 μL 11 to 14 Days
$881.83
Détails
Humain Lapin Inconjugué ELISA, WB   200 μL 11 to 16 Days
$658.43
Détails
Humain Lapin HRP ELISA, WB   200 μL 11 to 14 Days
$1,101.83
Détails

anti-SPPL3 Anticorps mieux référencés

  1. Human Polyclonal SPPL3 Primary Antibody pour ELISA - ABIN545304 : Grigorenko, Moliaka, Korovaitseva, Rogaev: Novel class of polytopic proteins with domains associated with putative protease activity. dans Biochemistry. Biokhimii?a 2002 (PubMed)
    Show all 2 Pubmed References

Plus d’anticorps contre SPPL3 partenaires d’interaction

Fruit Fly (Drosophila melanogaster) Signal Peptide Peptidase 3 (SPPL3) interaction partners

  1. Expression and characterization of signal peptide peptidase-like (sppL), a gene that encodes an intramembrane protease.

Zebrafish Signal Peptide Peptidase 3 (SPPL3) interaction partners

  1. SPPL2b is targeted through the secretory pathway to endosomes/lysosomes, whereas SPP and SPPL3 are restricted to the ER.

Caenorhabditis elegans (C. elegans) Signal Peptide Peptidase 3 (SPPL3) interaction partners

  1. study provides evidence that lmp-2, a key player in chaperone-mediated autophagy, is functional in C. elegans, too. Inhibition of lmp-2 prevents the reduction of proteasomal activity by glucose and thereby prevents also glucotoxicity

Mouse (Murine) Signal Peptide Peptidase 3 (SPPL3) interaction partners

  1. Our results identify SPPL3 as a cell-autonomous molecular determinant of NK cell maturation

Human Signal Peptide Peptidase 3 (SPPL3) interaction partners

  1. Data suggest that activation of the metalloproteinase ADAM10 by signal peptide peptidase-like 3 (SPPL3) triggered by mutant BRAF(V600E) was a critical transformation event.

  2. SPPL3 substrates identified on a proteome-wide scale in human and murine cells include numerous glycan-modifying enzymes residing in the Golgi network and implicated in distinct glycosylation pathways, including N-glycosylation, mucin-type O-glycosylation, O-mannosylation and glycosaminoglycan biosynthesis.

  3. SPPL3 cleaves Golgi type II membrane proteins leading to their secretion. SPPL3 substrates include Golgi glycosyltransferases MGAT5, B4GALT1, and B3GNT1. By facilitating disengagement of these glycosyltransferases from their membrane anchors, SPPL3 causes their premature secretion and consequently orchestrates the extent of N-glycosylation on human and murine cells.

  4. SPPL3 enhances the signal-induced association of stromal interaction molecule 1

  5. human SPPL3 is the first GxGD-type aspartyl protease shown to be capable of acting like a sheddase, similar to members of the rhomboid family, which belong to the class of intramembrane-cleaving serine proteases.

  6. SPP, SPPL2a, -2b, -2c, and -3 probably cleave type II-oriented substrate peptides as shown by consensus analysis

  7. SPPL2b is targeted through the secretory pathway to endosomes/lysosomes, whereas SPP and SPPL3 are restricted to the ER.

  8. SPPL3 cleaves a SPP substrate, but a more distantly related homologue SPPL2b does not, providing strong evidence that the malaria SPP and human SPPL3 have conserved active sites, while the active sites SPPL2b is distinct

SPPL3 profil antigène

Profil protéine

Intramembrane-cleaving aspartic protease (I-CLiP) that cleaves type II membrane signal peptides in the hydrophobic plane of the membrane.

Gene names and symbols associated with SPPL3

  • Signal peptide peptidase-like (SppL) anticorps
  • signal peptide peptidase like 3 (Sppl3) anticorps
  • signal peptide peptidase like 3 L homeolog (sppl3.L) anticorps
  • signal peptide peptidase like 3 (sppl3) anticorps
  • signal peptide peptidase like 3 (SPPL3) anticorps
  • signal peptide peptidase 3 (sppl3) anticorps
  • Intramembrane protease 2 (imp-2) anticorps
  • signal peptide peptidase 3 (Sppl3) anticorps
  • 4833416I09Rik anticorps
  • CG5901 anticorps
  • CG17370 anticorps
  • Dmel\\CG17370 anticorps
  • fb94d08 anticorps
  • IMP2 anticorps
  • MDHV1887 anticorps
  • MGC52975 anticorps
  • MGC75937 anticorps
  • PRO4332 anticorps
  • PSH1 anticorps
  • PSL4 anticorps
  • RGD1562826 anticorps
  • sppL anticorps
  • sppl3 anticorps
  • Sppl3-ps1 anticorps
  • Usmg3 anticorps
  • wu:fb94d08 anticorps
  • zgc:114093 anticorps

Protein level used designations for SPPL3

CG17370-PA , CG17370-PB , CG17370-PC , CG17370-PD , CG17370-PE , SPP-like protein 3 , SppL-PA , SppL-PB , SppL-PC , SppL-PD , SppL-PE , signal peptide peptidase-like , signal peptide peptidase 3 , signal peptide peptidase-like 3 , signal peptide peptidase-like 3, pseudogene 1 , signal peptide protease-like , signal peptide peptidase-like protein 3 , IMP-2 , SPP-like 3 protein , intramembrane protease 2 , presenilin-like protein 4 , upregulated during skeletal muscle growth 3 , SPP-like 3 , presenilin homologous protein 1

GENE ID SPECIES
43128 Drosophila melanogaster
360822 Rattus norvegicus
379304 Xenopus laevis
394539 Xenopus (Silurana) tropicalis
535156 Bos taurus
548609 Danio rerio
700898 Macaca mulatta
178013 Caenorhabditis elegans
74585 Mus musculus
121665 Homo sapiens
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