anti-Sirtuin 7 (SIRT7) Anticorps

SIRT7 encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. De plus, nous expédions Sirtuin 7 Kits (15) et Sirtuin 7 Protéines (15) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
SIRT7 51547 Q9NRC8
SIRT7 209011 Q8BKJ9
SIRT7 303745  
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Top anti-Sirtuin 7 Anticorps sur anticorps-enligne.fr

Showing 10 out of 174 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB <b>WB Suggested Anti-SIRT7 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>SH-SYSY cell lysate 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Boeuf (Vache) Lapin Inconjugué WB <b>WB Suggested Anti-SIRT7 Antibody Titration: </b>0.2-1 ug/ml<br><b>Positive Control: </b>Jurkat cell lysate 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Humain Lapin Inconjugué IHC (p), WB Anti- SIRT7 Picoband antibody, Western blotting All lanes: Anti SIRT7  at 0.5ug/ml Lane 1: Rat Spleen Tissue Lysate at 50ug Lane 2: Rat Brain Tissue Lysate at 50ug Lane 3: Rat Intestine Tissue Lysate at 50ug Lane 4: SMMC Whole Cell Lysate at 40ug Lane 5: JURKAT Whole Cell Lysate at 40ug Predicted bind size: 45KD Observed bind size: 45KD Anti- SIRT7 Picoband antibody, IHC(P) IHC(P): Mouse Spleen Tissue 100 μg Connectez-vous pour afficher 4 to 6 Days
$280.00
Détails
Humain Lapin Inconjugué IHC (p), WB Western blot analysis of SIRT7 (arrow) using SIRT7 Antibody (C-term) (ABIN390182). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the SIRT7 gene (Lane 2). Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Connectez-vous pour afficher 10 to 11 Days
$324.50
Détails
Humain Lapin Inconjugué WB Western Blot: SIRT7 Antibody [ABIN43538884] - Analysis of SIRT7 in A) human liver and B) PBMC lysate using this antibody at 1 ug/ml. 0.1 mg Connectez-vous pour afficher 7 to 9 Days
$345.00
Détails
Humain Lapin Inconjugué IF, IP, WB SIRT7 MaxPab rabbit polyclonal antibody. Western Blot analysis of SIRT7 expression in human liver. SIRT7 MaxPab rabbit polyclonal antibody. Western Blot analysis of SIRT7 expression in mouse liver. 100 μL Connectez-vous pour afficher 11 to 12 Days
$425.71
Détails
Humain Lapin Inconjugué WB 50 μg Connectez-vous pour afficher 2 to 3 Days
$205.00
Détails
Humain Lapin Inconjugué ICC, IF, IP SIRT7 Immunoprecipitated from human liver lysates with ABIN259767. A). ABIN259751 B). ABIN259749 Immunocytochemistry/Immunofluorescence: SIRT7 Antibody [ABIN2597682] - SIRT7 antibody was tested in U2OS cells with DyLight 488 (green). Nuclei and alpha-tubulin were counterstained with DAPI (blue) and Dylight 550 (red). 0.1 mL Connectez-vous pour afficher 7 to 9 Days
$444.19
Détails
Humain Lapin Inconjugué ICC, IF, WB Detection of SIRT7 in human liver lysates using ABIN259749. SIRT7 Immunoprecipitated from human liver lysates with ABIN259767. A). ABIN259751 B). ABIN259749 0.1 mL Connectez-vous pour afficher 7 to 9 Days
$444.19
Détails
Boeuf (Vache) Lapin Inconjugué ICC, IF, WB Detection of SIRT7 in human liver lysates using ABIN259751. SIRT7 Immunoprecipitated from human liver lysates with ABIN259767. A). ABIN259751 B). ABIN259749 0.1 mL Connectez-vous pour afficher 7 to 9 Days
$444.19
Détails

SIRT7 Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
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anti-Sirtuin 7 Anticorps mieux référencés

  1. Human Polyclonal SIRT7 Primary Antibody pour IHC (p), WB - ABIN390182 : Wang, Yi, Li, Cai, He, Ni, Zhou, Cheng, Jin, Fan, Qiu: Down-regulation of sirtuin 3 is associated with poor prognosis in hepatocellular carcinoma after resection. dans BMC cancer 2014 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal SIRT7 Primary Antibody pour IF, IP - ABIN950083 : Lim, Barker, Menon, Lappas: A Novel Role for SIRT3 in Regulating Mediators Involved in the Terminal Pathways of Human Labor and Delivery. dans Biology of reproduction 2016 (PubMed)
    Show all 2 Pubmed References

  3. Human Polyclonal SIRT7 Primary Antibody pour IHC (fro), IF (p) - ABIN760571 : Takumida, Takumida, Anniko: Localization of sirtuins in the mouse inner ear. dans Acta oto-laryngologica 2014 (PubMed)
    Show all 2 Pubmed References

  4. Human Polyclonal SIRT7 Primary Antibody pour ICC, IF - ABIN259767 : Zhang, Li, Deng, Liu, Chen, Tang, Wang, Cao, Fang, Wen, Xu, Chen, Shi, Li, Xie, Tang: Dicer interacts with SIRT7 and regulates H3K18 deacetylation in response to DNA damaging agents. dans Nucleic acids research 2016 (PubMed)

  5. Polyclonal SIRT7 Primary Antibody pour IP, WB - ABIN540297 : Frye: Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins. dans Biochemical and biophysical research communications 2000 (PubMed)

  6. Human Polyclonal SIRT7 Primary Antibody pour WB - ABIN4353888 : Alhazzazi, Kamarajan, Joo, Huang, Verdin, DSilva, Kapila: Sirtuin-3 (SIRT3), a novel potential therapeutic target for oral cancer. dans Cancer 2011 (PubMed)

Plus d’anticorps contre Sirtuin 7 partenaires d’interaction

Human Sirtuin 7 (SIRT7) interaction partners

  1. Authors evaluated the expression of known targets of miR (Montrer MLXIP Anticorps)-125a and found that sirtuin-7, matrix metalloproteinase-11 (Montrer MMP11 Anticorps), and c-Raf (Montrer RAF1 Anticorps) were up-regulated in tumor tissue by 2.2-, 3-, and 1.7-fold, respectively. Overall, these data support a tumor suppressor role for miR (Montrer MLXIP Anticorps)-125a.

  2. We found a negative correlation between mRNA levels of SIRT1 (Montrer SIRT1 Anticorps) in VAT of obese individuals and SIRT7 in VAT of the normal-weight subjects and expression of the relevant miRNAs.

  3. Data indicate the role of SIRT7 in inhibiting SMAD4 (Montrer SMAD4 Anticorps)-mediated breast cancer metastasis providing a possible therapeutic avenue.

  4. Energy stress strengthens SIRT7-mediated effects on Akt (Montrer AKT1 Anticorps) dephosphorylation.

  5. The SIRT7 is mobilized from the nucleolus to the nucleoplasm and promotes DDB1 deacetylation, leading to decreased DDB1-CUL4 association and CRL4 activity.

  6. Data suggest that SIRT7 undergoes Lys (Montrer LYZ Anticorps)-63 polyubiquitination, later removed by USP7 (Montrer USP7 Anticorps) to repress enzymatic activity of SIRT7; USP7 (Montrer USP7 Anticorps) and SIRT7 regulate gluconeogenesis via expression of glucose-6-phosphatase catalytic subunit (G6PC (Montrer G6PC Anticorps)); SIRT7 targets G6PC (Montrer G6PC Anticorps) promoter through ELK4 (Montrer ELK4 Anticorps). (SIRT7 = sirtuin 7; USP7 (Montrer USP7 Anticorps) = ubiquitin specific peptidase 7 (Montrer USP7 Anticorps); G6PC (Montrer G6PC Anticorps) = glucose-6-phosphatase catalytic subunit (Montrer G6PC Anticorps); ELK4 (Montrer ELK4 Anticorps) = transcription factor ELK4 (Montrer ELK4 Anticorps))

  7. the decline in SIRT7 in lung fibroblasts has a profibrotic effect, which is mediated by changes in Smad3 (Montrer SMAD3 Anticorps) levels.

  8. SIRT7 inhibits TR4 degradation by deacetylation of DDB1.

  9. miR (Montrer MLXIP Anticorps)-152/SIRT7 axis plays a key role in the regulation of Human dental pulp stem cell senescence.

  10. our study suggests that SIRT7 functions as an oncogene (Montrer RAB1A Anticorps) in non-small cell lung cancer (NSCLC), and miR (Montrer MLXIP Anticorps)-3666 can target SIRT7 to inhibit NSCLC cell growth by promoting the pro-apoptotic signaling pathway

Mouse (Murine) Sirtuin 7 (SIRT7) interaction partners

  1. the results of our study suggest that SIRT7 is involved in protecting neurons against OGD (Montrer FGFR1 Anticorps)/R-induced injury, possibly through regulation of the p53 (Montrer TP53 Anticorps)-mediated proapoptotic signaling pathway, indicating a potential therapeutic target for cerebral ischemia/reperfusion injury.

  2. Histological analysis revealed that there is no apparent structural abnormality of the amygdala and hippocampus, which are regions involved in fear memory consolidation, in Sirt7 KO mice. Our results indicate that SIRT7 is involved in the consolidation of fear memory.

  3. Data suggest that high-fat diet (HFD) alters regulation of expression of sirtuins (Sirt4 (Montrer SIRT4 Anticorps) and Sirt7) and enzymes in NAD biosynthetic pathway (Tdo2 (Montrer TDO2 Anticorps) and Nnmt (Montrer NNMT Anticorps)); these alterations are more prominent in liver as compared to white adipose tissue or skeletal muscle; Tdo2 (Montrer TDO2 Anticorps) and Nnmt (Montrer NNMT Anticorps) may serve as markers of HFD consumption. (Tdo2 (Montrer TDO2 Anticorps) = tryptophan 2,3-dioxygenase (Montrer TDO2 Anticorps); Nnmt (Montrer NNMT Anticorps) = nicotinamide N-methyltransferase (Montrer NNMT Anticorps))

  4. The Sirt7 mediates heterochromatin formation at rRNA genes through recruitment of DNA methyltransferase 1 (Montrer DNMT1 Anticorps) and another member of the sirtuin (Montrer SIRT1 Anticorps) family, Sirt1 (Montrer SIRT1 Anticorps).

  5. the decline in SIRT7 in lung fibroblasts has a profibrotic effect, which is mediated by changes in Smad3 (Montrer SMAD3 Anticorps) levels.

  6. SIRT7 inhibits TR4 degradation by deacetylation of DDB1.

  7. These results reveal a direct role for SIRT7 in double-strand break repair and establish a functional link between SIRT7-mediated histone H3 (Montrer HIST3H3 Anticorps) K18 (Montrer KRT18 Anticorps) deacetylation and the maintenance of genome integrity.

  8. miR (Montrer MLXIP Anticorps)-93 inhibits the metabolic target Sirt7, which we identified as a major driver of in vivo adipogenesis via induction of differentiation and maturation of early adipocyte precursors.

  9. The role of SIRT7 has emerged in protein synthesis, chromatin remodelling, cellular survival and lipid metabolism.

  10. SIRT7 stabilizes and activates the GABP alpha (Montrer GABPA Anticorps)/GABPbeta complex via deacetylation of GABPbeta1.

Sirtuin 7 (SIRT7) profil antigène

Profil protéine

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined\; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family.

Gene names and symbols associated with anti-Sirtuin 7 (SIRT7) Anticorps

  • sirtuin 7 (SIRT7) anticorps
  • sirtuin 7 (sirt7) anticorps
  • phosphate cytidylyltransferase 2, ethanolamine (PCYT2) anticorps
  • sirtuin 7 (Sirt7) anticorps
  • LOC796135 anticorps
  • SIR2L7 anticorps
  • SIRT7 anticorps

Protein level used designations for anti-Sirtuin 7 (SIRT7) Anticorps

sirtuin (silent mating type information regulation 2 homolog) 7 (S. cerevisiae) , sirtuin 7 , novel protein similar to vertebratesirtuin (silent mating type information regulation 2 homolog) 7 (S. cerevisiae) (SIRT7) , NAD-dependent deacetylase sirtuin-7 , sirtuin , NAD-dependent protein deacetylase sirtuin-7 , SIR2-like protein 7 , regulatory protein SIR2 homolog 7 , silent mating type information regulation 2, S.cerevisiae, homolog 7 , sir2-related protein type 7 , sirtuin type 7 , NAD-dependent deacetylase sirtuin 7

GENE ID SPECIES
454975 Pan troglodytes
796135 Danio rerio
422093 Gallus gallus
51547 Homo sapiens
209011 Mus musculus
303745 Rattus norvegicus
483371 Canis lupus familiaris
100125965 Sus scrofa
505662 Bos taurus
Fournisseurs de qualité sélectionnés pour anti-Sirtuin 7 (SIRT7) Anticorps
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