anti-Small Glutamine-Rich Tetratricopeptide Repeat (TPR)-Containing, alpha (SGTA) Anticorps

SGTA encodes a protein which is capable of interacting with the major nonstructural protein of parvovirus H-1 and 70-kDa heat shock cognate protein; however, its function is not known. De plus, nous expédions Small Glutamine-Rich Tetratricopeptide Repeat (TPR)-Containing, alpha Protéines (15) et et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
SGTA 6449 O43765
SGTA 52551 Q8BJU0
SGTA 64667 O70593
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Top anti-Small Glutamine-Rich Tetratricopeptide Repeat (TPR)-Containing, alpha Anticorps sur anticorps-enligne.fr

Showing 10 out of 82 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB 100 μL 2 to 3 Days
$289.00
Détails
Humain Lapin Inconjugué ELISA, IHC, WB ABIN6269674 at 1/100 staining human kidney tissue sections by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary. ABIN6269674 at 1/100 staining rat kidney tissue sections by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary. 100 μL 11 to 12 Days
$450.00
Détails
Humain Lapin Inconjugué IHC (p), WB WB Image Sample (50 ug of whole cell lysate) A: mouse liver 10% SDS PAGE antibody diluted at 1:1000 WB Image Sample (30 ug of whole cell lysate) A: Hep G2 , B: Molt-4 , 10% SDS PAGE antibody diluted at 1:5000 100 μL 3 to 4 Days
$466.18
Détails
Humain Lapin Inconjugué EIA, WB Western blot analysis using SGTA Antibody (Center) Cat.-No AP53893PU-N in Mouse liver tissue lysates (35ug/lane). This demonstrates the SGTA antibody detected the SGTA protein (arrow). 0.4 mL 6 to 8 Days
$484.00
Détails
Humain Lapin Inconjugué IP, WB SGTA MaxPab rabbit polyclonal antibody. Western Blot analysis of SGTA expression in human liver. SGTA MaxPab rabbit polyclonal antibody. Western Blot analysis of SGTA expression in mouse kidney. 100 μL 11 to 12 Days
$425.71
Détails
Humain Souris Inconjugué IF, WB Western Blot analysis of SGTA expression in transfected 293T cell line by SGTA MaxPab polyclonal antibody.Lane 1: SGTA transfected lysate(34.43 KDa).Lane 2: Non-transfected lysate. SGTA MaxPab polyclonal antibody. Western Blot analysis of SGTA expression in human liver. 50 μL 11 to 12 Days
$440.00
Détails
Humain Lapin Inconjugué IHC, WB ABIN6272880 at 1/100 staining Human breast cancer tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary. Western blot analysis of extracts of K-562 cells, using SGTA antibody. 100 μL 11 to 12 Days
$390.77
Détails
Souris Lapin Inconjugué ELISA, WB Western blot analysis of extracts of Mouse liver tissue sample,using SGTA Antibody(ABIN6270521). 100 μL 11 to 12 Days
$450.00
Détails
Humain Souris Inconjugué IF, IP, ELISA, WB SGTA monoclonal antibody (M06), clone 2E11 Western Blot analysis of SGTA expression in HeLa Immunofluorescence of monoclonal antibody to SGTA on HeLa cell. [antibody concentration 10 ug/ml] 100 μg 11 to 12 Days
$440.00
Détails
Souris Lapin Inconjugué WB Western blot analysis in mouse liver tissue lysates (35ug/lane). 400 μL 2 to 3 Days
$515.63
Détails

Plus d’anticorps contre Small Glutamine-Rich Tetratricopeptide Repeat (TPR)-Containing, alpha partenaires d’interaction

Human Small Glutamine-Rich Tetratricopeptide Repeat (TPR)-Containing, alpha (SGTA) interaction partners

  1. The SGTA is a co-chaperone that, in collaboration with the complex of BAG6, facilitates the biogenesis and quality control of hydrophobic proteins, protecting them from the aqueous cytosolic environment.

  2. the results provide novel insights into the structural complexity of SGTA and provide a new basis for mechanistic studies of substrate binding and release at the C-terminal region.

  3. evidence that the interaction can mediate the association of Rpn13 and SGTA in a cellular context.

  4. Coimmunoprecipitation studies indicated that non-glycosylated tetherin is stabilized through the formation of a ternary SGTA/Vpu/tetherin complex. Although the results do not provide support for a physiological function of SGTA in HIV-1 replication, they demonstrate that SGTA overexpression regulates tetherin expression and stability, thus providing insights into the function of SGTA in endoplasmic reticulum translocation

  5. study demonstrates a critical role of Hsc70 in SV40 endoplasmic reticulum-to-cytosol penetration and reveal how SGTA controls Hsc70 to impact this process

  6. the binding of SGTA to Rpn13 enables specific polypeptides to escape proteasomal degradation and/or selectively modulates substrate degradation.

  7. data suggest that SGTA regulates the cellular fate of a range of hydrophobic polypeptides should they become exposed to the cytosol.

  8. Data show that molecular chaperone BAG6_ubiquitin-like domain (UBL) and ubiquitin-like 4A UBL4A_UBL compete for the same binding site on N-terminal dimerisation domain of SGTA protein (SGTA_NT).

  9. SGTA overexpression may be involved in the pathogenesis of breast cancer which might serve as a future target for novel treatment in breast cancer.

  10. Our data suggest a role for SGTA at distinct steps in the chaperone-dependent modulation of androgen, glucocorticoid, and progesterone receptor activity.

  11. SGTA depletion decreased cyclin A and cyclin B levels.

  12. A role of SGTA in Non-Hodgkin's lymphoma (NHL) cell proliferation, adhesion and drug resistance, and it may pave the way for a novel therapeutic approach for cell adhesion-mediated drug resistance in NHL.

  13. High expression of SGTA in esophageal squamous cell carcinoma correlates with proliferation and poor prognosis.

  14. Univariate analysis showed that the low SGTB expression was associated with poor prognosis (P<0.001)

  15. showed a significant increase in the AR:SGTA ratio in cancerous lesions compared to patient-matched benign prostatic hyperplasia tissue

  16. High Small glutamine-rich tetratricopeptide repeat-containing protein alpha expression is associated with non-small-cell lung cancer tumorigenesis.

  17. SGTA is present in human ovaries and has the potential to modulate androgen receptor signalling, but it may not be differentially expressed in polycystic ovary syndrome.

  18. SGTA recognizes a noncanonical ubiquitin-like domain in the Bag6-Ubl4A-Trc35 complex to promote endoplasmic reticulum-associated degradation.

  19. Structures of the Sgt2/SGTA dimerization domain with the Get5/UBL4A UBL domain reveal an interaction that forms a conserved dynamic interface.

  20. Homodimerizaion of SGTA is dependent on the structural integrity of amino acids 1-80, and a core evolutionary conserved peptide within this region (amino acids 21-40) necessary for an effect of SGTA on the activity of the androgen receptor.

Mouse (Murine) Small Glutamine-Rich Tetratricopeptide Repeat (TPR)-Containing, alpha (SGTA) interaction partners

  1. In conclusion, this thorough investigation of SGTA-null mutation reports a mild phenotype of reduced body size.

  2. the binding of SGTA to Rpn13 enables specific polypeptides to escape proteasomal degradation and/or selectively modulates substrate degradation.

Small Glutamine-Rich Tetratricopeptide Repeat (TPR)-Containing, alpha (SGTA) profil antigène

Profil protéine

This gene encodes a protein which is capable of interacting with the major nonstructural protein of parvovirus H-1 and 70-kDa heat shock cognate protein\; however, its function is not known. Since this transcript is expressed ubiquitously in various tissues, this protein may serve a housekeeping function.

Gene names and symbols associated with SGTA

  • small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha (sgta) anticorps
  • small glutamine rich tetratricopeptide repeat containing alpha (SGTA) anticorps
  • small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta (sgtb) anticorps
  • small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha L homeolog (sgta.L) anticorps
  • small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha (Sgta) anticorps
  • small glutamine rich tetratricopeptide repeat containing alpha (Sgta) anticorps
  • 5330427H01Rik anticorps
  • AI194281 anticorps
  • alphaSGT anticorps
  • D10Ertd190e anticorps
  • hSGT anticorps
  • Sgt anticorps
  • SGTA anticorps
  • Stg anticorps
  • zgc:92462 anticorps

Protein level used designations for SGTA

small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha , small glutamine-rich tetratricopeptide , small glutamine-rich tetratricopeptide repeat-containing protein beta , small glutamine-rich tetratricopeptide repeat-containing protein alpha , UBP , alpha-SGT , protein containing three tetratricopeptide repeats , vpu-binding protein , small glutamine-rich tetratricopeptide repeat (TPR) containing protein , small glutamine-rich protein with tetratricopeptide repeats 1 , small glutamine-rich tetratricopeptide repeat (TPR) containing protein (SGT)

GENE ID SPECIES
394994 Xenopus (Silurana) tropicalis
426396 Gallus gallus
431772 Danio rerio
485067 Canis lupus familiaris
496358 Xenopus laevis
721574 Macaca mulatta
100583997 Nomascus leucogenys
100609678 Pan troglodytes
6449 Homo sapiens
52551 Mus musculus
64667 Rattus norvegicus
504701 Bos taurus
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