Sodium Channel, Voltage-Gated, Type VII, alpha Subunit (SCN7A) Kits ELISA

SCN7A encodes one of the many voltage-gated sodium channel proteins. De plus, nous expédions Sodium Channel, Voltage-Gated, Type VII, alpha Subunit Anticorps (42) et Sodium Channel, Voltage-Gated, Type VII, alpha Subunit Protéines (7) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
SCN7A 20272  
SCN7A 64155  
SCN7A 6332 Q01118
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Top Sodium Channel, Voltage-Gated, Type VII, alpha Subunit Kits ELISA sur anticorps-enligne.fr

Showing 3 out of 7 products:

Catalogue No. Reactivité Sensibilité Gamme Images Quantité Livraison Prix Détails
Humain 6.25 pg/mL 25-1600 pg/mL Typical standard curve 96 Tests 15 to 18 Days
$910.56
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Rat
  96 Tests 2 to 3 Days
$713.90
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Souris
  96 Tests 15 to 18 Days
$875.60
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Sodium Channel, Voltage-Gated, Type VII, alpha Subunit Kits ELISA mieux référencés

  1. Rat (Rattus) SCN7A Kit ELISA pour Sandwich ELISA - ABIN579335 : Wang, Fu, Wang, Liang, Wang, Yao, Chen, Li, Ying, Shi, Peng: Renal microvascular injury in chronic aristolochic acid nephropathy and protective effects of Cozaar. dans Renal failure 2011 (PubMed)
    Show all 2 Pubmed References

Plus Kits ELISA pour Sodium Channel, Voltage-Gated, Type VII, alpha Subunit partenaires d'interaction

Mouse (Murine) Sodium Channel, Voltage-Gated, Type VII, alpha Subunit (SCN7A) interaction partners

  1. Nax channels are expressed in specific glial cells in the organum vasculosum lamina terminalis which detects increases in Na(+) in body fluids.

  2. These results suggest that the Na(+) signal generated in Nax-positive glial cells leads to the activation of TRPV4-positive neurons in sCVOs to stimulate water intake by using EETs as gliotransmitters.

  3. SAP97 promotes the stability of Nax channels at the plasma membrane.

  4. Nax/Nav2 channel is expressed in alveolar type II cells, suggesting a role in the control of extracellular sodium level.

  5. Nav2-deficient mice show a preference for 0.15 M NaCl over water during a free two-choice intake test compared with wild-type; preference ratios for NaCl in wild tend to increase after combined superior laryngeal and glossopharyngeal nerve transection.

  6. Results show that the subfornical organ is the center of the control of salt-intake behavior in the brain, where the Na-level-sensitive Na(x) channel is involved in sensing the physiological increase in the Na level of body fluids.

  7. results suggest that glial cells bearing the Na(x) channel are the first to sense a physiological increase in the level of sodium in the body fluid.

  8. identified the promoter and transcription start sites of Na(x) sodium channel in dorsal root ganglia neurons; findings provide the basis with which to understand tissue-specific regulation of Nax sodium channel gene (Scn7a) expression

Human Sodium Channel, Voltage-Gated, Type VII, alpha Subunit (SCN7A) interaction partners

  1. The authors demonstrated that the sodium channel Nax functions as a sodium sensor. With increased extracellular sodium, Nax up-regulates prostasin, which results in activation of the sodium channel ENaC.

  2. SNP rs7565062 of SCN7A was significantly associated with essential hypertension in a Northern Han Chinese population

Sodium Channel, Voltage-Gated, Type VII, alpha Subunit (SCN7A) profil antigène

Antigen Summary

This gene encodes one of the many voltage-gated sodium channel proteins. For proper functioning of neurons and muscles during action potentials, voltage-gated sodium channels direct sodium ion diffusion for membrane depolarization. This sodium channel protein has some atypical characteristics\; the similarity between the human and mouse proteins is lower compared to other orthologous sodium channel pairs. Also, the S4 segments, which sense voltage changes, have fewer positive charged residues that in other sodium channels\; domain 4 has fewer arginine and lysine residues compared to other sodium channel proteins. Several alternatively spliced transcript variants exist, but the full-length natures of all of them remain unknown.

Gene names and symbols associated with SCN7A

  • sodium channel, voltage-gated, type VII, alpha (Scn7a) anticorps
  • sodium voltage-gated channel alpha subunit 7 (Scn7a) anticorps
  • sodium voltage-gated channel alpha subunit 7 (SCN7A) anticorps
  • 1110034K09Rik anticorps
  • AI642000 anticorps
  • Na-G anticorps
  • NaG anticorps
  • Nav2 anticorps
  • Nav2.1 anticorps
  • Nav2.2 anticorps
  • Nav2.3 anticorps
  • Nax anticorps
  • SCN6A anticorps

Protein level used designations for SCN7A

sodium channel, voltage-gated, type VI, alpha polypeptide , sodium channel, voltage-gated, type VII, alpha polypeptide , sodium channel protein type 7 subunit alpha , sodium channel voltage-gated type VI alpha polypeptide , sodium channel, voltage-gated, type 6, alpha polypeptide , putative voltage-gated sodium channel subunit alpha Nax , sodium channel protein cardiac and skeletal muscle subunit alpha , sodium channel protein type VII subunit alpha , voltage-dependent sodium channel alpha subunit

GENE ID SPECIES
20272 Mus musculus
64155 Rattus norvegicus
6332 Homo sapiens
100516881 Sus scrofa
507516 Bos taurus
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