Solute Carrier Family 16, Member 7 (Monocarboxylic Acid Transporter 2) (SLC16A7) Kits ELISA

SLC16A7 is a member of the monocarboxylate transporter family. De plus, nous expédions SLC16A7 Anticorps (84) et et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
SLC16A7 9194 O60669
SLC16A7 20503 O70451
SLC16A7 29735  
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Souris
  96 Tests 2 to 3 Days
$867.90
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  96 Tests 11 to 18 Days
$682.25
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  96 Tests 15 to 18 Days
$1,029.60
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Plus Kits ELISA pour SLC16A7 partenaires d'interaction

Human Solute Carrier Family 16, Member 7 (Monocarboxylic Acid Transporter 2) (SLC16A7) interaction partners

  1. MCT2 dictates the mode of action of N-oxalylglycine (NOG) by determining its intracellular concentration

  2. Adipocytes promote malignant growth of breast tumors with MCT2 expression via beta-hydroxybutyrate.

  3. SLC16A7 (MCT2) epigenetic regulation results in protein over-expression, affecting signalling and cellular phenotypes in prostate cancer

  4. Data suggest that monocarboxylate transporter 2 (MCT2) at peroxisomes is related to an increase in beta-oxidation levels which may be crucial for malignant transformation.

  5. This study identified that CGPs was found to significantly correlate with the differential expression and methylation of genes encoding solute carrier family 16, member 7.

  6. Our findings suggest that SNPs in MCT1 and MCT2 genes may affect clinical outcomes and can be used to predict the response to adjuvant chemotherapy in NSCLC patients who received surgical treatment once validated in future study.

  7. SNPs in MCT1 and MCT2 genes may affect clinical outcomes and can be used to predict the response to adjuvant chemotherapy in CRC patients who received surgical treatment.

  8. MCT2-3' UTR SNP (+2626 G > A) had a strong association with oligoasthenoteratozoospermia.

  9. this study provided evidence for the presence of MCT2 in prostate cancer, selectively labeling malignant glands.

  10. The monocarboxylate transporter 2 (MCT2) protein was tumor-selectively expressed in human colorectal malignancies and knockdown of MCT2 induces mitochondrial dysfunction, cell-cycle arrest, and senescence.

  11. Light microscopic immunohistochemistry revealed significantly less perivascular MCT2 immunoreactivity in the hippocampal formation in medial temporal lobe epilepsy than in non-MTLE patients

  12. Data show that a significant increase of MCT2 and MCT4 expression in the cytoplasm of tumour cells and a significant decrease in both MCT1 and CD147 expression in prostate tumour cells was observed when compared to normal tissue.

  13. data suggest that extracellular membrane-bound CAIV, but not cytosolic CAII, augments transport activity of MCT2 in a non-catalytic manner, possibly by facilitating a proton pathway other than His-88

  14. MCT1, MCT2, and MCT4 protein expression in breast, colon, lung, and ovary neoplasms, as well as CD147 and CD44, were analysed.

  15. Ocular absorption of monocarboxylic acid drugs may be enhanced by MCT transporter SLC16A7, and the absorption route provided by this transporter may be utilized to improve the bioavailability of topically applied ophthalmic drugs.

  16. Data suggest that hypoxia increases lactate release from adipocytes and modulates MCT expression in a type-specific manner, with MCT1 and MCT4, but not MCT2 expression, being hypoxia-inducible transcription factor-1 (HIF-1) dependent.

  17. MCT2 immunoreactivity was noted in astrocytic cell bodies from week 19 and spread subsequently to the astrocyte end-feet in contact with blood vessels of visual cortex.

  18. Gamma-hydroxybutyric acid (GHB) is a substrate for both MCT2 and MCT4.

  19. Colorectal neoplasms showed a loss of expression of MCT2 in plasma membranes.

  20. These data demonstrate neuronal MCT2 expression in human, but since a portion of it exhibits a distinct synaptic localization, it further supports a putative role for MCT2 in adjustment of energy supply to levels of activity.

Mouse (Murine) Solute Carrier Family 16, Member 7 (Monocarboxylic Acid Transporter 2) (SLC16A7) interaction partners

  1. MCT2 dictates the mode of action of N-oxalylglycine (NOG) by determining its intracellular concentration

  2. MCT1 and MCT2 not only play an important role in the transport of ketone bodies, but also in the modulation of brain energy metabolism under normal and ketogenic conditions.

  3. Adipocytes promote malignant growth of mammary gland tumors with MCT2 expression via beta-hydroxybutyrate.

  4. These results suggest that basigin has a functional role as a binding partner with MCT2 in testicular and epididymal spermatozoa.

  5. This study demonstrated that MCT2 was up regulation in ipsilateral site of brain afeter cerebral ischemia.

  6. MCT2 distribution coupled with lactate uptake by hypothalamic neurons suggests that hypothalamic neurons control food intake using lactate to reflect changes in glucose levels.

  7. Data suggest that basigin interacts with MCT1 and MCT2 to locate them properly in the membrane of spermatogenic cells and that this may enable sperm to utilize lactate as an energy substrate contributing to cell survival.

  8. Glucose-deprived cleavage stage embryos, undergo oxidative stress and exhibit elevated ROS, which in turn upregulates PPARA, catalase and SLC16A7 in a classical peroxisomal proliferation response.

  9. These results demonstrate that MCT2 expression can be upregulated together with other key postsynaptic proteins in vivo under conditions related to synaptic plasticity

  10. changes in MCT2 expression could participate in the process of synaptic plasticity induced by BDNF

  11. data provide convincing evidence that MCT2 represents a major neuronal monocarboxylate transporter in the adult mouse brain

  12. In mouse cortical neurons MCT2 is the major monocarboxylate transporter; its expression is correlated with synaptic development.

  13. Regulation of expression of MCT1 and MCT2 was investigated in mouse cortical neurons; neither noradrenaline, dibutyryl cAMP nor forskolin affected MCT2 mRNA expression

  14. Noradrenaline induces an increase in neuronal MCT2 protein expression by a mechanism involving stimulation of phosphoinositide 3-kinase/Akt and translational activation via the mTOR/S6 kinase pathway.

  15. Expression of cerebral MCT isoforms can be modulated by alterations of peripheral metabolism, suggesting that the adult brain is sensitive and adapts to new metabolic states.

  16. Transfection assays demonstrate that three regions contained a functional promoter and that the in vitro, cell type-specific activities of these promoters are consistent with tissue-specific expression.

  17. Unique roles for slc16a7 in monocarboxylate transport and pH regulation during preimplantation development.

  18. Cellular expression of a sodium-dependent monocarboxylate transporter (Slc5a8) and the MCT1/2 in the mouse kidney.

  19. MCT2 is linked to AMPA receptor GluR2/3 subunits and undergoes a similar translocation process in neurons upon activation

Cow (Bovine) Solute Carrier Family 16, Member 7 (Monocarboxylic Acid Transporter 2) (SLC16A7) interaction partners

  1. immunohistochemical studies localized MCT2, MCT7, and MCT8 proteins in the cattle rumen, abomasum, jejunum, and caecum.

Zebrafish Solute Carrier Family 16, Member 7 (Monocarboxylic Acid Transporter 2) (SLC16A7) interaction partners

  1. Data indicate that monocarboxylate transporters (MCTs1-4) were all found to be expressed in brains of embryos, and were localized in both neurons and astrocyte.

SLC16A7 profil antigène

Antigen Summary

This gene is a member of the monocarboxylate transporter family. Members in this family transport metabolites, such as lactate, pyruvate, and ketone bodies. The protein encoded by this gene catalyzes the proton-linked transport of monocarboxylates and has the highest affinity for pyruvate. This protein has been reported to be more highly expressed in prostate and colorectal cancer specimens when compared to control specimens. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with SLC16A7

  • solute carrier family 16 member 7 (SLC16A7) anticorps
  • solute carrier family 16 (monocarboxylic acid transporters), member 7 (Slc16a7) anticorps
  • solute carrier family 16 member 7 (Slc16a7) anticorps
  • solute carrier family 16, member 7 (monocarboxylic acid transporter 2) (slc16a7) anticorps
  • 4921534N07Rik anticorps
  • Mct2 anticorps
  • zgc:123207 anticorps

Protein level used designations for SLC16A7

monocarboxylate transporter 2 , solute carrier family 16, member 7 (monocarboxylic acid transporter 2) , MCT 2 , solute carrier family 16 member 7 , solute carrier family 16 (monocarboxylic acid transporters), member 7 , Solute carrier family 16 member 7 , MCT2

GENE ID SPECIES
9194 Homo sapiens
20503 Mus musculus
29735 Rattus norvegicus
417815 Gallus gallus
614573 Bos taurus
101835011 Mesocricetus auratus
100715442 Cavia porcellus
641419 Danio rerio
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