Solute Carrier Family 16 (Monocarboxylic Acid Transporters), Member 3 (SLC16A3) Kits ELISA

Lactic acid and pyruvate transport across plasma membranes is catalyzed by members of the proton-linked monocarboxylate transporter (MCT) family, which has been designated solute carrier family-16. De plus, nous expédions Solute Carrier Family 16 (Monocarboxylic Acid Transporters), Member 3 Anticorps (68) et Solute Carrier Family 16 (Monocarboxylic Acid Transporters), Member 3 Protéines (4) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
SLC16A3 9123 O15427
Anti-Rat SLC16A3 SLC16A3 80878 O35910
Anti-Souris SLC16A3 SLC16A3 80879 P57787
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Catalogue No. Reactivité Sensibilité Gamme Images Quantité Livraison Prix Détails
Humain 0.28 ng/mL 0.78 ng/mL - 50 ng/mL 96 Tests 13 to 16 Days
$736.84
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Plus Kits ELISA pour Solute Carrier Family 16 (Monocarboxylic Acid Transporters), Member 3 partenaires d'interaction

Human Solute Carrier Family 16 (Monocarboxylic Acid Transporters), Member 3 (SLC16A3) interaction partners

  1. these data suggest that the key effect of MCT4 depletion on NK cells probably utilizes inductive autophagy as a compensatory metabolic mechanism to minimize the acidic extracellular microenvironment associated with lactate export in tumors.

  2. MCT1 may be acting as an uptake transporter and MCT4 as an efflux system across the basolateral membrane for ferulic acid, and that this process is stimulated by butyric acid.

  3. Ocular absorption of monocarboxylic acid drugs may be enhanced by MCT transporter SLC16A3, and the absorption route provided by the transporter may be utilized to improve the bioavailability of topically applied ophthalmic drugs.

  4. Gamma-hydroxybutyric acid (GHB) is a substrate for both MCT2 and MCT4.

Mouse (Murine) Solute Carrier Family 16 (Monocarboxylic Acid Transporters), Member 3 (SLC16A3) interaction partners

  1. MCT1 inhibition impairs proliferation of glycolytic breast cancer cells co-expressing MCT1 and MCT4 via disruption of pyruvate rather than lactate export.

  2. This study demonstrated that MCT4 was up regulation in the brain afeter cerebral ischemia.

  3. The soleus, liver and heart were the main tissues that showed improved the MCT1 mRNA expression, indicating its important role in controlling MLSS concentration in mice.

  4. MCT4-overexpressing mesenchymal stem cells preferentially induced cell death in cardiomyocytes.

  5. MCT4 depletion induced cell death characterized by elevated reactive oxygen species and metabolic crisis. In xenograft models, MCT4 had a significant impact on tumor metabolism and was required for rapid tumor growth.

  6. MCT4 is up-regulated in inflammation-activated macrophages and required for innate immune response.

  7. Nitric oxide represents an intercellular signal to control MCT4 expression in astrocytes; in doing so, it facilitates lactate transfer to other surrounding cell types in the central nervous system.

  8. MCT4 expression markedly increased the gradient between intracellular and extracellular pH from 0.14 to 0.43.

  9. MCT1 and MCT4 protein expression increased by 92 and 61%, respectively, after 12 days of functional overload (p < 0.05).

  10. In situ hybridization survey of MCT subtypes in placenta detected intense mRNA expression of MCT1, MCT4, & MCT9 (gestational day 11.5 through day 18.5); subcellular localization of MCT1 & MCT4 in cell membrane is opposite polarity found in human.

  11. Unique roles for slc16a3 in monocarboxylate transport and pH regulation during preimplantation development.

Cow (Bovine) Solute Carrier Family 16 (Monocarboxylic Acid Transporters), Member 3 (SLC16A3) interaction partners

  1. Results suggest that monocarboxylate transporter 4 (MCT4) can play an important role in the transport of short-chain fatty acid

Zebrafish Solute Carrier Family 16 (Monocarboxylic Acid Transporters), Member 3 (SLC16A3) interaction partners

  1. Data indicate that monocarboxylate transporters (MCTs1-4) were all found to be expressed in brains of embryos, and were localized in both neurons and astrocyte.

Solute Carrier Family 16 (Monocarboxylic Acid Transporters), Member 3 (SLC16A3) profil antigène

Antigen Summary

Lactic acid and pyruvate transport across plasma membranes is catalyzed by members of the proton-linked monocarboxylate transporter (MCT) family, which has been designated solute carrier family-16. Each MCT appears to have slightly different substrate and inhibitor specificities and transport kinetics, which are related to the metabolic requirements of the tissues in which it is found. The MCTs, which include MCT1 (SLC16A1\; MIM 600682) and MCT2 (SLC16A7\; MIM 603654), are characterized by 12 predicted transmembrane domains (Price et al., 1998

Gene names and symbols associated with SLC16A3

  • solute carrier family 16 member 3 (SLC16A3) anticorps
  • solute carrier family 16 member 3 L homeolog (slc16a3.L) anticorps
  • solute carrier family 16 member 3 (Slc16a3) anticorps
  • solute carrier family 16 (monocarboxylic acid transporters), member 3 (Slc16a3) anticorps
  • solute carrier family 16 (monocarboxylate transporter), member 3 (slc16a3) anticorps
  • mct anticorps
  • MCT-3 anticorps
  • MCT-4 anticorps
  • MCT 3 anticorps
  • Mct3 anticorps
  • MCT 4 anticorps
  • Mct4 anticorps
  • MCT4b anticorps
  • slc16a3b anticorps
  • wu:fd20b02 anticorps
  • wu:fi38f12 anticorps
  • zgc:55905 anticorps

Protein level used designations for SLC16A3

monocarboxylate transporter 3 , monocarboxylate transporter 4 , solute carrier family 16 (monocarboxylic acid transporters), member 3 , solute carrier family 16, member 3 (monocarboxylic acid transporter 4) , solute carrier family 16, member 3 (monocarboxylic acid transporter 4) b , MCT 3 , MCT 4 , solute carrier family 16 member 3 , MCT4 , monocarboxylate transporter 4b

GENE ID SPECIES
9123 Homo sapiens
444516 Xenopus laevis
454988 Pan troglodytes
483379 Canis lupus familiaris
715842 Macaca mulatta
100158243 Sus scrofa
80878 Rattus norvegicus
80879 Mus musculus
395383 Gallus gallus
510085 Bos taurus
327276 Danio rerio
100715111 Cavia porcellus
100171995 Pongo abelii
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