anti-Solute Carrier Family 18 (Vesicular Monoamine Transporter), Member 2 (SLC18A2) Anticorps

Involved in the ATP-dependent vesicular transport of biogenic amine neurotransmitters. De plus, nous expédions Solute Carrier Family 18 (Vesicular Monoamine Transporter), Member 2 Kits (6) et Solute Carrier Family 18 (Vesicular Monoamine Transporter), Member 2 Protéines (4) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
SLC18A2 214084 Q8BRU6
SLC18A2 25549 Q01827
SLC18A2    
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Top anti-Solute Carrier Family 18 (Vesicular Monoamine Transporter), Member 2 Anticorps sur anticorps-enligne.fr

Showing 10 out of 79 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué IHC, WB WB Suggested Anti-SLC18A2 Antibody Titration:  0.2-1 ug/ml  Positive Control:  Jurkat cell lysate mouse and rat brain 100 μL 2 to 3 Days
$289.00
Détails
Humain Chèvre Inconjugué IHC, ELISA, WB Antibody (1µg/ml) staining of Human Placenta (A), Human Uterus (B), Human Adrenal Gland (C) and Human Pancreas (D) lysates (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. ABIN570915 (1µg/ml) staining of Human Placenta (A) and Human Adrenal Gland (B) lysate (35µg protein in RIPA buffer). Detected by chemiluminescence. 100 μg 6 to 7 Days
$429.84
Détails
Humain Souris Inconjugué IHC, IHC (p), WB 100 μL 11 to 14 Days
$522.50
Détails
Humain Souris Inconjugué FACS, IF, IHC, WB Anti-SLC18A2 mouse monoclonal antibody (ABIN2452654) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY SLC18A2 (RC221342). HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SLC18A2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-SLC18A2. 0.1 mL 2 to 3 Days
$482.90
Détails
Humain Souris Inconjugué FACS, IF, IHC, IHC (p), WB 100 μL 11 to 14 Days
$522.50
Détails
Boeuf (Vache) Lapin Inconjugué WB 100 μL 11 to 14 Days
$551.83
Détails
Boeuf (Vache) Chèvre Inconjugué EIA, IHC (p), WB 0.1 mg 6 to 8 Days
$445.50
Détails
Humain Lapin Inconjugué ELISA, IHC, WB Western blot analysis of extracts ofHeLa, using SLC18A2 antibody.  The lane on the left is treated with the antigen-specific peptide. ABIN6277346 at 1/100 staining Human urothelial cancer tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22¡ãC. An HRP conjugated goat anti-rabbit antibody was used as the secondary 100 μL 11 to 12 Days
$390.77
Détails
Humain Chèvre Inconjugué ELISA, IHC, WB ABIN5855385 (1 µg/ml) staining of Human Placenta (A) and Human Adrenal Gland (B) lysate (35 µg protein in RIPA buffer). Detected by chemiluminescence. ABIN5855385 (5 µg/ml) staining of paraffin embedded Human Pancreas. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. 200 μL 7 to 11 Days
$412.19
Détails
Humain Lapin Inconjugué IHC, WB 100 μL 11 to 13 Days
$366.77
Détails

anti-Solute Carrier Family 18 (Vesicular Monoamine Transporter), Member 2 Anticorps mieux référencés

  1. Human Polyclonal SLC18A2 Primary Antibody pour IHC (fro), IHC - ABIN259010 : Sala, Brighina, Saracchi, Fermi, Riva, Carrozza, Pirovano, Ferrarese: Vesicular monoamine transporter 2 mRNA levels are reduced in platelets from patients with Parkinson's disease. dans Journal of neural transmission (Vienna, Austria : 1996) 2010 (PubMed)
    Show all 8 Pubmed References

  2. Human Polyclonal SLC18A2 Primary Antibody pour IHC - ABIN967117 : Surratt, Persico, Yang, Edgar, Bird, Hawkins, Griffin, Li, Jabs, Uhl: A human synaptic vesicle monoamine transporter cDNA predicts posttranslational modifications, reveals chromosome 10 gene localization and identifies TaqI RFLPs. dans FEBS letters 1993 (PubMed)
    Show all 5 Pubmed References

  3. Human Polyclonal SLC18A2 Primary Antibody pour ELISA, ICC - ABIN4365633 : Erickson, Eiden, Hoffman: Expression cloning of a reserpine-sensitive vesicular monoamine transporter. dans Proceedings of the National Academy of Sciences of the United States of America 1992 (PubMed)
    Show all 2 Pubmed References

  4. Human Monoclonal SLC18A2 Primary Antibody pour FACS, IF - ABIN2732150 : Tong, Boileau, Furukawa, Chang, Wilson, Houle, Kish: Distribution of vesicular monoamine transporter 2 protein in human brain: implications for brain imaging studies. dans Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2011 (PubMed)
    Show all 2 Pubmed References

  5. Human Monoclonal SLC18A2 Primary Antibody pour FACS, ICC - ABIN4365634 : Shin, Duong, Nguyen, Li, Bing, Bach, Park, Nakayama, Ali, Kanthasamy, Cadet, Nabeshima, Kim: Role of oxidative stress in methamphetamine-induced dopaminergic toxicity mediated by protein kinase Cδ. dans Behavioural brain research 2012 (PubMed)

  6. Human Polyclonal SLC18A2 Primary Antibody pour IHC, IHC (p) - ABIN4251662 : Reichard, Nanaware-Kharade, Gonzalez, Thakkar, Owens, Peterson: PEGylation of a High-Affinity Anti-(+)Methamphetamine Single Chain Antibody Fragment Extends Functional Half-Life by Reducing Clearance. dans Pharmaceutical research 2016 (PubMed)

  7. Rat (Rattus) Polyclonal SLC18A2 Primary Antibody pour IEM, ICC - ABIN947486 : Xenias, Ibáñez-Sandoval, Koós, Tepper: Are striatal tyrosine hydroxylase interneurons dopaminergic? dans The Journal of neuroscience : the official journal of the Society for Neuroscience 2015 (PubMed)

Plus d’anticorps contre Solute Carrier Family 18 (Vesicular Monoamine Transporter), Member 2 partenaires d’interaction

Mouse (Murine) Solute Carrier Family 18 (Vesicular Monoamine Transporter), Member 2 (SLC18A2) interaction partners

  1. This study highlights a non-cytotoxic role of dopamine in a genetic model of VMAT2 deletion exclusively in nigrostriatal neurons.

  2. results confirm the role of VMAT2 in the protection of vulnerable nigrostriatal dopamine neurons and may also provide new insight into the side effects of L-DOPA treatments in Parkinson's disease

  3. Study identified an importance for VMAT2-mediated neurotransmission in mediating hedonic feeding and binge-like eating behavior, providing novel insight on the interactive roles of leptin and dopamine, two of the most extensively studied brain systems, in obesity development.

  4. In vivo imaging of the striatal vesicular monoamine transporter type 2 (VMAT2) distribution using 18F-FP-(+)-DTBZ animal PET is a useful method to evaluate the efficacy of therapeutic drugs i.e., magnolol, for the management of Parkinson's disease .

  5. Intravenous use of a psychostimulant drug containing methcathinone (ephedrone) and manganese causes an irreversible extrapyramidal syndrome; study reproduced the syndrome in mice to evaluate dopaminergic damage. Increased [(11)C]dihydrotetrabenazine binding may indicate vesicular monoamine transporter type 2 (VMAT2) function is altered.

  6. In contrast to their loss of catecholamine neurons of the substantia nigra and locus ceruleus, aged VMAT2 LO mice do not exhibit a change in the number of serotonergic (TPH2+) neurons within the dorsal raphe

  7. Rotenone induces dopamine neuron death through a series of sequential events including microtubule destabilization, JNK3 activation, VMAT2 inhibition, accumulation of cytosolic dopamine, and generation of ROS.

  8. increased release of dopamine and neuroprotection from MPTP toxicity in the VMAT2-overexpressing mice suggest that interventions aimed at enhancing vesicular capacity may be of therapeutic benefit in Parkinson disease

  9. The coordinate loss of dopamine and norepinephrine neurons in VMAT2 LO mice parallels the pattern of neurodegeneration that occurs in human PD.

  10. findings support the idea that altered DAT and VMAT2 expression affect age-related changes in dopaminergic function.

  11. Data suggest that pancreatic islets of mice and rats do not contain VMAT2, except in mast cells and sympathetic nerve terminals that innervate the islets.

  12. VMAT2 expression was increased by Nurr1 gene activation in lactacystin-lesioned mice.

  13. Data show that alpha-synuclein transcription is inversely correlated with neurite growth and VMAT2 expression, and inhibition of RhoA leads to a decrease in alpha-synuclein.

  14. The expression of VMAT2 is increased significantly in hippocampal formation of 14-3-3 epsilon knockout mouse model compared to that of wild-type littermates.

  15. VMAT2 up-regulation might be a compensatory mechanism to restore and maintain synaptic transmission in dopaminergic midbrain neurons during nicotine withdrawal.

  16. mice with reduced expression of VMAT2 (heterozygote) are more sensitive to the neurotoxic effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and methamphetamine

  17. The vesicular monoamine content regulates VMAT2 activity through Galphaq in mouse platelets.

  18. Deletions of the VMAT2 gene increase ethanol consumption in male knockout mice.

  19. The relative importance of the DAT and terminal autoreceptors as control mechanisms in the actions of amphetamine are reversed in VMAT2 deficient mutant mice

  20. physiological changes in VMAT2 levels or trafficking at the synapse may regulate dopamine release by altering the ratio of fillable-to-empty synaptic vesicles, as both continue to cycle in response to neural activity

Solute Carrier Family 18 (Vesicular Monoamine Transporter), Member 2 (SLC18A2) profil antigène

Profil protéine

Involved in the ATP-dependent vesicular transport of biogenic amine neurotransmitters. Pumps cytosolic monoamines including dopamine, norepinephrine, serotonin, and histamine into synaptic vesicles. Requisite for vesicular amine storage prior to secretion via exocytosis (By similarity). {ECO:0000250}.

Gene names and symbols associated with SLC18A2

  • solute carrier family 18 (vesicular monoamine), member 2 (Slc18a2) anticorps
  • solute carrier family 18 member A2 (Slc18a2) anticorps
  • 1110037L13Rik anticorps
  • 9330105E13 anticorps
  • MNAT anticorps
  • VAT2 anticorps
  • VMAT-2 anticorps
  • VMAT2 anticorps

Protein level used designations for SLC18A2

Monoamine transporter , Solute carrier family 18 member 2 , VAT2 , Vesicular amine transporter 2 , monoamine transporter , solute carrier family 18 member 2 , synaptic vesicular amine transporter , vesicular amine transporter 2 , vesicular monoamine transporter 2 , Solute carrier family 18 A2 (vesicular monoamine transporter 2) , solute carrier family 18 (vesicular monoamine transporter), member 2 , solute carrier family 18 (vesicular monoamine), member 2

GENE ID SPECIES
214084 Mus musculus
25549 Rattus norvegicus
Fournisseurs de qualité sélectionnés pour anti-Solute Carrier Family 18 (Vesicular Monoamine Transporter), Member 2 (SLC18A2) Anticorps
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