anti-Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 2 (SLC2A2) Anticorps

Glucose transporter 2 isoform is an integral plasma membrane glycoprotein of the liver, islet beta cells, intestine, and kidney epithelium. De plus, nous expédions Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 2 Kits (26) et Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 2 Protéines (6) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
SLC2A2 25351  
SLC2A2 6514 P11168
SLC2A2 20526 P14246
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Top anti-Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 2 Anticorps sur anticorps-enligne.fr

Showing 10 out of 196 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB Host: Rabbit  Target Name: SLC2A2  Sample Tissue: Fetal LungLane A:  Primary Antibody Lane B:  Primary Antibody + Blocking Peptide Primary Antibody Concentration: 1 µg/mL Peptide Concentration: 5 µg/mL Lysate Quantity: 41 µg/laneGel Concentration:.12 % 100 μL 2 to 3 Days
$319.00
Détails
Humain Lapin Inconjugué IHC (p), WB Anti- SLC2A2 Picoband antibody, IHC(P) IHC(P): Human Liver Cancer Tissue Anti- SLC2A2 Picoband antibody, Western blotting All lanes: Anti SLC2A2  at 0.5ug/ml Lane 1: PANC Whole Cell Lysate at 40ug Lane 2: A549 Whole Cell Lysate at 40ug Lane 3:  Whole Cell Lysate at 40ug Predicted bind size: 57KD Observed bind size: 50KD 100 μg 4 to 6 Days
$280.00
Détails
Humain Lapin Inconjugué FACS, IF (p), IHC (p), WB Human HT-29 lysates probed with Rabbit Anti-Glut2 Polyclonal Antibody, Unconjugated  at 1:5000 for 90 min at 37˚C. 100 μL 3 to 7 Days
$339.90
Détails
Humain Lapin Inconjugué WB Western blot analysis of GLUT2 expression in HEK293T (A), rat kidney (B) whole cell lysates. 200 μL 13 to 14 Days
$487.50
Détails
Humain Chèvre Inconjugué IHC, IHC (p) Liver, Human: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg 11 to 14 Days
$484.00
Détails
Humain Lapin Inconjugué ELISA, FLISA, IHC, WB Immunohistochemistry of Anti-Glut2 Antibody. Tissue: mouse kidney. Antigen retrieval: Heat Induced, slides incubated in sodium citrate buffer for 1hr at 90°C. Primary: Rabbit Anti-Glut2 Antibody at 5µg/mL overnight. Blocking: 2% goat serum in TBST. Secondary: Alexa 488 at 1µg/mL for 2hrs at room temperature. Western Blot of Rabbit anti-Glut2 antibody. Lane 1: HEK293 lysate. Load: 10µg per lane. Primary antibody: Glut2 antibody at 1:1000 for overnight at 4°C. Secondary antibody: Peroxidase rabbit secondary antibody at 1:40,000 for 30 min at RT. Block: ABIN925618 overnight at 4°C. Predicted/Observed size: ~60 kDa. 100 μg 5 to 7 Days
$613.50
Détails
Humain Lapin Inconjugué EIA, WB 0.4 mL 6 to 8 Days
$522.50
Détails
Chien Lapin Inconjugué WB 100 μL 11 to 14 Days
$581.17
Détails
Humain Lapin Inconjugué ELISA, IHC, WB Western Blot of Rabbit anti-Glut2 antibody. Lane 1: mouse liver lysate. Lane 2: mouse pancreas lysate. Load: 10µg per lane. Primary antibody: Glut2 antibody at 1:500 for overnight at 4°C. Secondary antibody: Peroxidase rabbit secondary antibody at 1:40,000 for 30 min at RT. Block: 0.75% Casein/TBS overnight at 4°C. Predicted/Observed size: 57.1 kDa. 100 μL 5 to 7 Days
$613.50
Détails
Humain Lapin Inconjugué ELISA, WB Western blot analysis SLC2A2 using Jurkat whole cell lysates 100 μL 11 to 12 Days
$390.77
Détails

anti-Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 2 Anticorps mieux référencés

  1. Human Polyclonal SLC2A2 Primary Antibody pour ICC, IF - ABIN4314601 : Micucci, Orciari, Catalano: Hyperglycemia promotes K-Ras-induced lung tumorigenesis through BASCs amplification. dans PLoS ONE 2014 (PubMed)
    Show all 5 Pubmed References

  2. Human Polyclonal SLC2A2 Primary Antibody pour FACS, IF (p) - ABIN739124 : Guttman, Yossef, Freixo-Lima, Rider, Porgador, Lewis: ?1-Antitrypsin modifies general NK cell interactions with dendritic cells and specific interactions with islet ?-cells in favor of protection from autoimmune diabetes. dans Immunology 2014 (PubMed)
    Show all 4 Pubmed References

  3. Human Monoclonal SLC2A2 Primary Antibody pour CyTOF, FACS - ABIN4899161 : Kornete, Beauchemin, Polychronakos, Piccirillo: Pancreatic islet cell phenotype and endocrine function throughout diabetes development in non-obese diabetic mice. dans Autoimmunity 2013 (PubMed)
    Show all 4 Pubmed References

  4. Human Polyclonal SLC2A2 Primary Antibody pour ELISA, WB - ABIN544117 : Laukkanen, Lindström, Eriksson, Valle, Hämäläinen, Ilanne-Parikka, Keinänen-Kiukaanniemi, Tuomilehto, Uusitupa, Laakso: Polymorphisms in the SLC2A2 (GLUT2) gene are associated with the conversion from impaired glucose tolerance to type 2 diabetes: the Finnish Diabetes Prevention Study. dans Diabetes 2005 (PubMed)
    Show all 3 Pubmed References

  5. Human Polyclonal SLC2A2 Primary Antibody pour ELISA, FLISA - ABIN5596790 : Liang, Yee, Chien, Chen, Luo, Zou, Piao, Mifune, Chen, Calvert, King, Norheim, Abad, Krauss, Giacomini: Organic cation transporter 1 (OCT1) modulates multiple cardiometabolic traits through effects on hepatic thiamine content. dans PLoS biology 2019 (PubMed)
    Show all 3 Pubmed References

  6. Human Monoclonal SLC2A2 Primary Antibody pour FACS - ABIN4895679 : Michau, Guillemain, Grosfeld, Vuillaumier-Barrot, Grand, Keck, LHoste, Chateau, Serradas, Teulon, De Lonlay, Scharfmann, Brot-Laroche, Leturque, Le Gall: Mutations in SLC2A2 gene reveal hGLUT2 function in pancreatic β cell development. dans The Journal of biological chemistry 2013 (PubMed)
    Show all 2 Pubmed References

  7. Human Polyclonal SLC2A2 Primary Antibody pour IHC, WB - ABIN6147959 : Zang, Fan, Chen, Huang, Qin: Improvement of Lipid and Glucose Metabolism by Capsiate in Palmitic Acid-Treated HepG2 Cells via Activation of the AMPK/SIRT1 Signaling Pathway. dans Journal of agricultural and food chemistry 2018 (PubMed)

  8. Cow (Bovine) Polyclonal SLC2A2 Primary Antibody pour WB - ABIN2776949 : Klinger, Lange, Brandt, Hustedt, Schröder, Breves, Herrmann: Degree of SGLT1 phosphorylation is associated with but does not determine segment-specific glucose transport features in the porcine small intestines. dans Physiological reports 2018 (PubMed)
    Show all 2 Pubmed References

  9. Human Polyclonal SLC2A2 Primary Antibody pour IHC (p), WB - ABIN3043928 : Wu, Guo, Lu, Wu, Pan, Su: Impact of perinatal exposure to acetaminophen on hepatocellular metabolic function in offspring. dans American journal of translational research 2017 (PubMed)

Plus d’anticorps contre Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 2 partenaires d’interaction

Zebrafish Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 2 (SLC2A2) interaction partners

  1. Glut2 has an essential role during brain development by facilitating the uptake and availability of glucose and support the involvement of glut2 in brain glucose sensing.

  2. The structure and function of GLUT2 has been remarkably well conserved during vertebrate evolution and open the way for the use of zebrafish as a model species in which to study the biology and pathophysiology of GLUT2.

Human Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 2 (SLC2A2) interaction partners

  1. The variant rs8192675 in the SLC2A2 gene (C allele) is associated with an improved glucose response to metformin monotherapy during the first year after diagnosis in type 2 diabetes.

  2. High GLUT2 levels were detected in all cell lines.

  3. SGLT1, SGLT2 and GLUT2 have roles in renal glucose handling [review]

  4. Data suggest that the following genetic modifications are involved in neonatal diabetes mellitus patients in Oman: (1) mutation in KCNJ11 (potassium voltage-gated channel subfamily J member 11; one patient); (2) mutation in GCK (glucokinase); (3) mutation in SLC2A2 (glucose transporter type 2); (4) chromosome 6q24 methylation abnormalities.

  5. Results showed the glucose transporter GLUT2 was highly expressed in the lumen of sweat glands from atopic dermatitis (AD) patients. AD patients with chronic inflammation had significantly increased GLUT2 mRNA expression and near normal sweat glucose levels.

  6. Data suggest expression of SGLT1 is markedly increased in kidney of patients with type 2 diabetes as compared to control subjects; SGLT1 mRNA is highly and significantly correlated with fasting and postprandial plasma glucose and HbA1c. In contrast, data suggest SGLT2 and GLUT2 mRNA in kidney are down-regulated in type 2 diabetes, but not to statistically significant level. (SGLT = sodium-glucose co-transporter)

  7. The levels of GLUT1 and GLUT3, the major brain glucose transporters, are decreased, especially in the cerebral cortex in patient with Alzheimer disease.

  8. The mutant tumors exhibited impaired proliferation, anoikis resistance, and migratory capability and had reduced adenylate energy charge. Further investigations also revealed that cANGPTL4 regulated the expression of Glut2

  9. Single nucleotide polymorphism in SLC2A2 gene is associated with glycemic response to metformin in Type 2 diabetes.

  10. no significant associations between GLUT2 and/or TAS1R2 polymorphisms and fillings were found, but allele frequencies of the TAS1R2 variant were marginally significantly different between children with DMFT = 0 and DMFT >/=1. no significant interaction between both genes and risk of dental caries was found. GLUT2 and TASR1 polymorphisms may influence the risk of caries in the Czech population

  11. Three novel variants and seven single-nucleotide polymorphisms associated with the myelomeningocele phenotype.

  12. Homozygous splice-site mutation IVS8+5G>C (c.1068+5 G>C) of SLC2A2 was found in patient A and homozygous nonsense mutation c.1194T>A (p.Tyr398X) in patient B. Patient C harboured a missense mutation c.380C>A (p.Ala127Asp)

  13. Data identified the last enzyme of the de novo purine synthesis pathway 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase (ATIC)and the putative tyrosine phosphatase PTPLAD1 as new regulators of Glut2(SLC2A2)translocation in HEK293 cells. SiRNA-mediated knockdown of ATIC delayed insulin response of Glut2 translocation while depletion of PTPLAD1(HACD3} strongly enhanced it in HEK293 cells.

  14. A novel 6 nucleotide deletion in GLUT2 gene, a member of the facilitative glucose transporter family, is shown to be segregated with Fanconi-Bickel syndrome in an Iranian family.

  15. SGLT1 or GLUT2 interact with the cytoskeleton in the intestinal epithelium during hexose absorption.

  16. Mutations in the GLUT2 gene is associated with ccute metabolic acidosis in Fanconi-Bickel syndrome.

  17. GLUT-2 expression may be associated with cholangiocarcinogenesis of large bile duct and is a helpful marker for detecting high-grade biliary intraepithelial neoplasia lesions in atypical bile ducts.

  18. SGLT1 mRNA and GLUT2 mRNA expression are reduced significantly in CACo-2 cells exposed to berry extracts.

  19. the first gain of function mutations for hGLUT2, revealing the importance of its receptor versus transporter function in pancreatic beta cell development and insulin secretion.

  20. associated with caries risk

Pig (Porcine) Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 2 (SLC2A2) interaction partners

  1. the effects of Transmissible gastroenteritis virus infection on glucose uptake and SGLT1 and GLUT2 expression, are reported.

  2. analysis of time- and breed-specific expression patterns of GLUT2 and GLUT4, which highlight their potential as candidate genes for assessing adipose deposition and muscle development in pigs

Cow (Bovine) Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 2 (SLC2A2) interaction partners

  1. The coding regions of GHSR and SLC2A2 were sequenced in 12 animals with extreme phenotypes for feed intake and gain; Sixteen SNPs were identified in SLC2A2, and three were detected in GHSR.

Mouse (Murine) Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 2 (SLC2A2) interaction partners

  1. High basolateral glucose increases Sglt2 and reduces Sirt1 in renal tubules through GLUT2.

  2. GLUT2-mediated glucosamine transport stimulates mouse embryonic stem cell proliferation.

  3. the first intracellular loop of GLUT4 contains the retention motif WLGRK, in which W105 plays a prominent role.

  4. hypothalamic arcuate nucleus (Arc)POMC-deficient mice, which develop severe obesity and insulin resistance, unexpectedly exhibit improved glucose tolerance and remain protected from hyperglycemia via decreased renal GLUT2 expression and glycosuria.

  5. analysis of the different diabetic responses to STZ in two different animal strains, which both have similar initial GLUT2 expressions in beta cells

  6. The study demonstrates a previously unrecognized mechanism that controls insulin expression through c-Abl-regulated NKx2.2 and GLUT2.

  7. role of SGLT1 and GLUT2 in intestinal glucose transport and sensing

  8. GLUT2-dependent control of parasympathetic activity defines a nervous system/endocrine pancreas axis that is critical for beta cell mass establishment.

  9. Embryonic stem cells isolated in physiological-glucose media retain a functional Glut2 transporter that is expressed by embryos.

  10. in SAMP8 mice, treatment decreased the expression of glucagon, GLUT2, somatostatin and insulin mRNA.

  11. Dysglycosylation of GLUT2 is associated with its re-distribution to lipid-raft microdomain in pancreatic beta cells.

  12. Intestinal dehydroascorbic acid (DHA) transport is mediated by the facilitative sugar transporters, GLUT2 and GLUT8

  13. In contrast to islets from the most widely used T1D model, the NOD mouse, human islets predominantly express GLUT1 and, to a much lesser extent, GLUT3 on their surface instead of GLUT2.

  14. In human enterocytes, GLUT2 was consistently located in basolateral membranes; mice on a low-carbohydrate/high-fat diet for 12 months also exhibited endosomal GLUT2 accumulation and reduced glucose absorption.

  15. Our data provide evidence that glucose detection by GLUT2 contributes to the control of food intake by the hypothalamus

  16. regulatory control loop between gut leptin and intestinal GLUT2/GLUT5 transporters links to hepatic metabolic functions in rodents

  17. This transporter is essential for glucose sensing by pancreatic beta-cells, by the hepatoportal sensor and by sensors in the ANS.

  18. GLUT2 and GLUT5 could exert complementary roles in adapting the absorption capacity of the intestine to occasional or repeated loads of dietary sugars.

  19. Susceptibility of endothelial cells to glucose toxicity may be the result of theincreased expression of GLUT-2.

  20. central glucose sensors require glut2 expression in glial cells and couple glial cells and neurons

Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 2 (SLC2A2) profil antigène

Profil protéine

Glucose transporter 2 isoform is an integral plasma membrane glycoprotein of the liver, islet beta cells, intestine, and kidney epithelium. It mediates facilitated bidirectional glucose transport. Because of its low affinity for glucose, it has been suggested as a glucose sensor.

Gene names and symbols associated with SLC2A2

  • solute carrier family 2 (facilitated glucose transporter), member 2 (slc2a2) anticorps
  • solute carrier family 2 member 2 L homeolog (slc2a2.L) anticorps
  • solute carrier family 2 member 2 (SLC2A2) anticorps
  • solute carrier family 2 member 2 (slc2a2) anticorps
  • solute carrier family 2, facilitated glucose transporter member 2 (LOC100534484) anticorps
  • solute carrier family 2 member 2 (Slc2a2) anticorps
  • solute carrier family 2 (facilitated glucose transporter), member 2 (Slc2a2) anticorps
  • AI266973 anticorps
  • Glut-2 anticorps
  • Glut2 anticorps
  • GTT2 anticorps
  • MGC83262 anticorps
  • SLC2A2 anticorps
  • wu:fb62h10 anticorps

Protein level used designations for SLC2A2

solute carrier family 2, facilitated glucose transporter member 2 , zglut2 , solute carrier family 2 (facilitated glucose transporter), member 2 , glucose transporter 2 , solute carrier family 2, facilitated glucose transporter member 2-like , GLUT-2 , glucose transporter type 2, liver , liver-type glucose transporter , facilitative glucose transporter

GENE ID SPECIES
322493 Danio rerio
432042 Xenopus laevis
460848 Pan troglodytes
488165 Canis lupus familiaris
496943 Xenopus (Silurana) tropicalis
695538 Macaca mulatta
100033974 Equus caballus
100142681 Felis catus
100397713 Callithrix jacchus
100437366 Pongo abelii
100475889 Ailuropoda melanoleuca
100534484 Oreochromis niloticus
25351 Rattus norvegicus
6514 Homo sapiens
397429 Sus scrofa
282357 Bos taurus
20526 Mus musculus
396272 Gallus gallus
443205 Ovis aries
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