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SLC22A13 encodes a member of the organic-cation transporter family. De plus, nous expédions et beaucoup plus de produits pour cette protéine.
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An adenovirus expressing ORCTL3 leads to growth inhibition of renal tumours in vivo and to substantial destruction of patients' kidney tumour cells ex vivo
Since ORCTL3 targets fatty acid metabolism in transformed cells and induces an ER stress specifically in these cells, it reveals a novel therapeutic interference option for tumor cells.
Expression of SLC22A13 stimulates efflux of aspartate and glutamate (Montrer GRIN1 Protéines) at the basolateral membrane in renal collecting duct.
SLC22A13 is a new urate and high affinity nicotinate transporter
ORCTL3 protein causes cell death in v-src (Montrer SRC Protéines)-transformed cells and in various human tumor cell lines but not in normal cells or untransformed cell lines.
This gene encodes a member of the organic-cation transporter family. It is located in a gene cluster with another member of the family, organic cation transporter like 4. The encoded protein is a transmembrane protein involved in the transport of small molecules. This protein can function to mediate urate uptake and is a high affinity nicotinate exchanger in the kidneys and the intestine.
solute carrier family 22 (organic cation transporter), member 13
, solute carrier family 22, member 13
, organic cation transporter-like 3
, organic cationic transporter-like 3
, organic-cation transporter like 3
, solute carrier family 22 (organic anion transporter), member 13
, solute carrier family 22 member 13