anti-Solute Carrier Family 3 (Activators of Dibasic and Neutral Amino Acid Transport), Member 2 (SLC3A2) Anticorps

SLC3A2 is a member of the solute carrier family and encodes a cell surface, transmembrane protein. De plus, nous expédions SLC3A2 Protéines (29) et SLC3A2 Kits (8) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
SLC3A2 6520 P08195
SLC3A2 50567 Q794F9
SLC3A2 17254 P10852
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Top anti-SLC3A2 Anticorps sur anticorps-enligne.fr

Showing 10 out of 270 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Livraison Prix Détails
Humain Lapin Inconjugué IP, IHC (p), ELISA, WB Immunochemical staining of human SLC3A2 in human kidney with rabbit polyclonal antibody (1 µg/mL, formalin-fixed paraffin embedded sections). Immunochemical staining of human SLC3A2 in human placenta with rabbit polyclonal antibody (1 µg/mL, formalin-fixed paraffin embedded sections). The left panel: tissue incubated with primary antibody; The right panel: tissue incubated with the mixture of p 100 μL 14 to 16 Days
$247.82
Détails
Humain Lapin Inconjugué IHC (p), WB WB Image Sample (30 ug of whole cell lysate) A: Molt-4 , 7.5% SDS PAGE antibody diluted at 1:1000 IHC-P Image Immunohistochemical analysis of paraffin-embedded SCC15 xenograft, using CD98, antibody at 1:100 dilution. 100 μL 3 to 4 Days
$466.18
Détails
Humain Souris Inconjugué FACS, IHC (p), IP Surface staining of human peripheral blood monocytes with anti-human CD98 (MEM-108) purified, GAM-APC. 0.1 mg 5 to 7 Days
$350.66
Détails
Humain Lapin Inconjugué IF (p), IHC (p), WB Lane 1: rat brain lysates Lane 2: human colon carcinoma lysates probed with Anti CD98 Polyclonal Antibody, Unconjugated (ABIN719546) at 1:200 in 4 °C. Followed by conjugation to secondary antibody at 1:3000 90min in 37 °C. Predicted band 68kD. Observed band size: 68kD. Formalin-fixed and paraffin embedded rat colitis tissue labeled with Anti CD98 Polyclonal Antibody, Unconjugated (ABIN719546) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL 3 to 7 Days
$339.90
Détails
Humain Lapin Inconjugué ELISA, WB 100 μL 11 to 13 Days
$359.79
Détails
Humain Lapin Inconjugué WB Western blot analysis of CD98 expression in SW480 (A), SKOV3 (B), mouse kidney (C), mouse lung (D) whole cell lysates. 200 μL 13 to 14 Days
$487.50
Détails
Humain Souris FITC FACS, IHC (p), IP Surface staining of human peripheral blood cells with anti-human CD98 (MEM-108) FITC. Cells in the monocyte gate were used for analysis. 100 Tests 5 to 7 Days
$417.45
Détails
Humain Souris Biotin FACS, IHC (p), IP Surface staining of human peripheral blood cells with anti-human CD98 (MEM-108) FITC. Cells in the monocyte gate were used for analysis. 0.1 mg 5 to 7 Days
$417.45
Détails
Humain Souris PE FACS, IHC (p), IP Surface staining of human peripheral blood cells with anti-human CD98 (MEM-108) FITC. Cells in the monocyte gate were used for analysis. 100 Tests 5 to 7 Days
$484.24
Détails
Humain Souris Inconjugué FACS, IHC, IHC (fro), IHC (p), IP Human, Testis: Formalin-Fixed, Paraffin-Embedded (FFPE) Anti-SLC3A2 antibody IHC of human, testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 15 ug/ml. This image was taken for the unconjugated form of this product. Other ... 50 μg 11 to 14 Days
$484.00
Détails

anti-SLC3A2 Anticorps mieux référencés

  1. Human Polyclonal SLC3A2 Primary Antibody pour IHC (fro), WB - ABIN548987 : Kim, Kanai, Chairoungdua, Cha, Matsuo, Kim, Inatomi, Sawa, Ida, Endou: Human cystine/glutamate transporter: cDNA cloning and upregulation by oxidative stress in glioma cells. dans Biochimica et biophysica acta 2001 (PubMed)
    Show all 5 Pubmed References

  2. Rat (Rattus) Polyclonal SLC3A2 Primary Antibody pour IHC (fro), WB - ABIN548991 : Segawa, Fukasawa, Miyamoto, Takeda, Endou, Kanai: Identification and functional characterization of a Na+-independent neutral amino acid transporter with broad substrate selectivity. dans The Journal of biological chemistry 1999 (PubMed)
    Show all 5 Pubmed References

  3. Human Monoclonal SLC3A2 Primary Antibody pour FACS, IP - ABIN533485 : Nakamura, Sato, Yang, Miyagawa, Harasaki, Tomita, Matsuoka, Noma, Iwai, Minato: 4F2 (CD98) heavy chain is associated covalently with an amino acid transporter and controls intracellular trafficking and membrane topology of 4F2 heterodimer. dans The Journal of biological chemistry 1999 (PubMed)
    Show all 5 Pubmed References

  4. Human Monoclonal SLC3A2 Primary Antibody pour FACS - ABIN536606 : Dalton, Christian, Redman, Sargent, Boyd: Differential effect of cross-linking the CD98 heavy chain on fusion and amino acid transport in the human placental trophoblast (BeWo) cell line. dans Biochimica et biophysica acta 2007 (PubMed)
    Show all 3 Pubmed References

  5. Human Monoclonal SLC3A2 Primary Antibody pour FACS - ABIN536605 : Cho, Skubitz, Katz, Chain: CD98-dependent homotypic aggregation is associated with translocation of protein kinase Cdelta and activation of mitogen-activated protein kinases. dans Experimental cell research 2003 (PubMed)
    Show all 3 Pubmed References

  6. Human Polyclonal SLC3A2 Primary Antibody pour IF (p), IHC (p) - ABIN719546 : Hutterer, Ebner, Riemenschneider, Willuweit, McCoy, Egger, Schröder, Wendl, Hellwig, Grosse, Menhart, Proescholdt, Fritsch, Urbach, Stockhammer, Roelcke, Galldiks, Meyer, Langen, Hau, Trinka: Epileptic Activity Increases Cerebral Amino Acid Transport Assessed by 18F-Fluoroethyl-l-Tyrosine Amino Acid PET: A Potential Brain Tumor Mimic. dans Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2016 (PubMed)
    Show all 2 Pubmed References

  7. Human Monoclonal SLC3A2 Primary Antibody pour Func, FACS - ABIN610337 : Fisher, Pevsner, Burgoyne: Control of fusion pore dynamics during exocytosis by Munc18. dans Science (New York, N.Y.) 2001 (PubMed)
    Show all 2 Pubmed References

  8. Human Monoclonal SLC3A2 Primary Antibody pour Func, FACS - ABIN610336 : Shuang, Zhang, Fletcher, Groblewski, Pevsner, Stuenkel: Regulation of Munc-18/syntaxin 1A interaction by cyclin-dependent kinase 5 in nerve endings. dans The Journal of biological chemistry 1998 (PubMed)
    Show all 2 Pubmed References

  9. Mouse (Murine) Monoclonal SLC3A2 Primary Antibody pour IHC (fro), FACS - ABIN2689466 : Chan, Hämmerling, Stutman: The Ly-10 antigen is a marker of mouse-activated T lymphocytes. dans Immunogenetics 1988 (PubMed)

  10. Mouse (Murine) Monoclonal SLC3A2 Primary Antibody pour FACS - ABIN2472890 : Kang, Zhao, Lovaas, Eisenberg, Greene: Clathrin-independent internalization of normal cellular prion protein in neuroblastoma cells is associated with the Arf6 pathway. dans Journal of cell science 2009 (PubMed)

Plus d’anticorps contre SLC3A2 partenaires d’interaction

Human Solute Carrier Family 3 (Activators of Dibasic and Neutral Amino Acid Transport), Member 2 (SLC3A2) interaction partners

  1. these data suggest that SLC3A2 plays an important role in regulating Hepatitis C virus entry

  2. SLC7A5 and SLC3A2 structures are analyzed together with lower resolution cryo-EM structure, and multibody 3D auto-refinement against single-particle cryo-EM data was used to characterize the dynamics of the interaction of CD98hc and LAT1.

  3. LAT1 and 4F2hc were identified as significant independent markers for predicting a worse prognosis in patients with pulmonary pleomorphic carcinoma

  4. this study showed that integrin co-receptor, SLC3A2, required for cell proliferation, is expressed at the surface of resting dermal fibroblasts in young patients and is reduced drastically with aging

  5. Sorafenib induced translocation of miR-21 to the nucleus, where it promoted the expression of SNHG1, resulting in upregulation of SLC3A2, leading to the activation of Akt pathway

  6. cryo-electron microscopy structures of human LAT1-4F2hc alone and in complex with the inhibitor 2-amino-2-norbornanecarboxylic acid at resolutions of 3.3 A and 3.5 A, respectively

  7. SLC3A2 appears to play a role in the aggressive Breast cancer ( BC) subtypes driven by MYC and could act as a potential prognostic marker. Functional assessment is necessary to reveal its potential therapeutic value in the different BC subtypes.

  8. LAT1 was closely associated with the expression of 4F2hc and phosphorylation of the mTOR pathway. LAT1 is a significant molecular marker used to predict prognosis after surgical resection of colorectal cancer patients.

  9. The low expression of CD98 is a novel biomarker for predicting poor prognosis in patients with cutaneous angiosarcoma.

  10. our findings demonstrated that low expression of miR-490-3p or high expression of PPM1F was positively associated with poor survival and tumor recurrence in patients with HCC, and miR-490-3p suppressed cell proliferation and invasion by targeting PPM1F.

  11. Data suggest that SLC3A2-NRG1 should be considered a therapeutic target for patients with invasive mucinous adenocarcinoma of the lung (IMA).

  12. These results demonstrate a novel fundamental role of LAT1 to support the protein expression of 4F2hc via a chaperone-like function in chorionic trophoblasts.

  13. SLC3A2 is upregulated in osteosarcoma and plays a crucial role in tumor growth.

  14. Expression levels of CD98 and beta1-integrin-A (the activated form of beta1-integrin) were significantly increased in hepatocellular carcinoma (HCC) tissues relative to those of normal liver tissues.

  15. Data suggest that increased CD98 (4F2hc) expression plays an essential role in tumor aggressiveness and metastasis.

  16. Study demonstrated that the mRNA expression levels of the two system xc- subunits, SLC7A11 and SLC3A2, in peripheral white blood cells are lowered in patients with schizophrenia than healthy individuals

  17. ubiquitylation and the resulting downregulation of CD98 can limit cell proliferation and clonal expansion.

  18. exposure to diesel exhaust particle extract induces functional overexpression of the amino acid transporter LAT1/CD98hc in lung cells

  19. The detergent-induced stabilization of the purified human 4F2hc-LAT2 complex presented here paves the way towards its crystallization and structure determination at high-resolution

  20. HSV-1 recruited cellular fusion regulatory proteins CD98hc and beta1 integrin to the nuclear membrane for viral de-envelopment fusion.

Mouse (Murine) Solute Carrier Family 3 (Activators of Dibasic and Neutral Amino Acid Transport), Member 2 (SLC3A2) interaction partners

  1. Inhibition of the amino acid transporter CD98/LAT1 abrogated the leucine-driven mTORC1 activation and reduced natural killer cell effector function

  2. SLC3A2 dermal fibroblast deletion induced major skin phenotypes resembling premature aging

  3. Cell metabolism regulates integrin mechanosensing via an SLC3A2-dependent sphingolipid biosynthesis pathway.

  4. Slc3a2 is required for branched-chain amino-acid-dependent maintenance of Treg cells.

  5. CD98hc expression in vascular smooth muscle cells contributes to the formation of plaques that are morphologically more stable, and thereby protects against atherothrombosis.

  6. These results demonstrate a novel fundamental role of LAT1 to support the protein expression of 4F2hc via a chaperone-like function in chorionic trophoblasts.

  7. CD98 is required for endothelial cell growth. CD98-specific reagents could have a dual anticancer effect: directly by inhibiting tumor cell proliferation and indirectly by preventing tumor angiogenesis

  8. Taken together, our data indicate that T cell-specific deletion of CD98hc can contribute to the prevention of GvHD development due to the attenuation of lymphocyte migration and by increasing the generation of Treg cells.

  9. data establish CD98hc as a master protective gene at the cross-road of redox control and AA availability, making it a relevant therapeutic target in cancer.

  10. ubiquitylation and the resulting downregulation of CD98 can limit cell proliferation and clonal expansion.

  11. CD98hc mediated this stiffness sensing by increasing Rho kinase (ROCK) activity.

  12. Mice lacking CD98hc in B cells are protected from experimental autoimmune encephalomyelitis.

  13. CD98 heavy chain is crucial for T cell-mediated autoimmune colitis. CD98 heavy chain deficiency in T cells is involved in increasing induced regulatory T cells.

  14. The role of SLC3A2 in keratinocytes is not in cell adhesion but, instead, in cell proliferation and migration through modulating integrin signaling by the Src-RhoA pathway.

  15. CD98-dependent amino acid transport increased renal tubular epithelial cell proliferation is mediated by Erk and p38 MAPK signaling.

  16. Investigated the contribution of CD98 to intestinal tumorigenesis in Apc(Min/+) mice and the underlying mechanism of action.

  17. when the CD98hc deficient macrophages were stimulated with either IFN-gamma/LPS or IL-4, the production of NO(2) or arginase-I decreased in comparison to that observed in the control macrophages

  18. T cell-specific deficiency in CD98hc can contribute to cardiac allograft permanent acceptance correlating with the attenuation of lymphocyte migration and by increasing the generation of regulatory T cells.

  19. Taken together, these observations show that the combination of an inflammatory context and intestinal epithelial cell expression of CD98 affects the regulation of miRNA expression in colonic epithelial and immune cells.

  20. CD98 expression modulates intestinal homeostasis, inflammation, and colitis-associated cancer in mice

Zebrafish Solute Carrier Family 3 (Activators of Dibasic and Neutral Amino Acid Transport), Member 2 (SLC3A2) interaction partners

  1. Slc3a2 inhibits the RhoA/ROCK pathway via phosphorylation of c-Src to modulate YSL microtubule dynamics.

SLC3A2 profil antigène

Profil protéine

This gene is a member of the solute carrier family and encodes a cell surface, transmembrane protein. The protein exists as the heavy chain of a heterodimer, covalently bound through di-sulfide bonds to one of several possible light chains. The encoded transporter plays a role in regulation of intracellular calcium levels and transports L-type amino acids. Alternatively spliced transcript variants, encoding different isoforms, have been characterized.

Gene names and symbols associated with SLC3A2

  • solute carrier family 3 member 2 (SLC3A2) anticorps
  • solute carrier family 3 member 2 (Slc3a2) anticorps
  • solute carrier family 3 (amino acid transporter heavy chain), member 2 L homeolog (slc3a2.L) anticorps
  • solute carrier family 3 (amino acid transporter heavy chain), member 2 S homeolog (slc3a2.S) anticorps
  • solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 (Slc3a2) anticorps
  • solute carrier family 3 (amino acid transporter heavy chain), member 2a (slc3a2a) anticorps
  • 4F2 anticorps
  • 4F2HC anticorps
  • 4T2HC anticorps
  • AI314110 anticorps
  • Cd98 anticorps
  • CD98HC anticorps
  • fc65h12 anticorps
  • Ly-10 anticorps
  • Ly-m10 anticorps
  • Ly10 anticorps
  • Mdu1 anticorps
  • MGC53951 anticorps
  • MGC53965 anticorps
  • Mgp-2hc anticorps
  • NACAE anticorps
  • SLC3A2 anticorps
  • wu:fc65h12 anticorps

Protein level used designations for SLC3A2

4F2 cell-surface antigen heavy chain , CD98 heavy chain , antigen defined by monoclonal antibody 4F2, heavy chain , antigen identified by monoclonal antibodies 4F2, TRA1.10, TROP4, and T43 , lymphocyte activation antigen 4F2 large subunit , monoclonal antibody 44D7 , solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 , 4F2hc , antigen identified by monoclonal antibodies 4F2 , solute carrier family 3, member 2 , blood-brain barrier large neutral amino acid transporter heavy chain 4F2 , CD98 antigen , type II transmembrane protein , solute carrier family 3 (amino acid transporter heavy chain), member 2a , solute carrier family 3, member 2a

GENE ID SPECIES
6520 Homo sapiens
50567 Rattus norvegicus
379133 Xenopus laevis
379938 Xenopus laevis
451271 Pan troglodytes
483777 Canis lupus familiaris
507107 Bos taurus
100009363 Oryctolagus cuniculus
100064046 Equus caballus
100144589 Sus scrofa
100172374 Pongo abelii
100585864 Nomascus leucogenys
17254 Mus musculus
796322 Danio rerio
101866986 Macaca fascicularis
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