Sortilin-Related VPS10 Domain Containing Receptor 3 (SORCS3) Kits ELISA

SORCS3 encodes one family member of vacuolar protein sorting 10 (VPS10) domain-containing receptor proteins. De plus, nous expédions SORCS3 Anticorps (23) et SORCS3 Protéines (5) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
Anti-Rat SORCS3 SORCS3 294043  
SORCS3 22986 Q9UPU3
SORCS3 66673 Q8VI51
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Humain
  96 Tests 26 to 36 Days
$899.80
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  96 Tests 21 to 31 Days
$796.95
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Plus Kits ELISA pour SORCS3 partenaires d'interaction

Human Sortilin-Related VPS10 Domain Containing Receptor 3 (SORCS3) interaction partners

  1. First study reporting on human subjects with a SORCS3 gene defect with infantile spasms and intellectual disability; this supports the important role of SORCS3 in the central nervous system.

  2. SORCS3 may be important in MS pathogenesis.

  3. Here the authors have characterized SorCS1, SorCS2 and SorCS3 using biochemical methods and electron microscopy. They found that their purified extracellular domains co-exist in stable dimeric and monomeric populations.

  4. The propeptide is not a requirement for normal processing of the receptor and does not prevent ligands from binding to the SorCS3 precursor form

Mouse (Murine) Sortilin-Related VPS10 Domain Containing Receptor 3 (SORCS3) interaction partners

  1. our findings identified a novel role for VPS10P domain receptors SORCS1 and SORCS3 in hypothalamic control of metabolism through regulation of orexigenic peptide production.

  2. SorCS3 serves as a key regulator of synaptic transmission and plasticity. Results show that glutamate receptor functions are controlled by SorCS3 to secure correct functioning of excitatory synapses. The receptor plays a more central role in CA1 compared to the dentate gyrus, correlating well with the expression pattern. Reduced function of SorCS3 results in impaired synaptic mechanisms in the hippocampus.

  3. Study demonstrates that SorCS3 expression is restricted to the developing and adult nervous system

  4. Sortilin-related receptor SORCS3 is a postsynaptic modulator of synaptic depression and fear extinction.

  5. SorCS3 and the homologous sorCS1 and sorCS2 genes were expressed in a combinatorial mostly non-overlapping pattern in the developing and mature central nervous system; activity-dependent induction of sorCS3 did not require protein synthesis

SORCS3 profil antigène

Antigen Summary

This gene encodes one family member of vacuolar protein sorting 10 (VPS10) domain-containing receptor proteins. The VPS10 domain name comes from the yeast carboxypeptidase Y sorting receptor Vps10 protein. Members of this gene family are large with many exons but the CDS lengths are usually less than 3700 nt. Very large introns typically separate the exons encoding the VPS10 domain\; the remaining exons are separated by much smaller-sized introns. These genes are strongly expressed in the central nervous system. Two of the five family members (sortilin and sortilin-related receptor) are synthesized as preproproteins\; it is not yet known if this encoded protein is also a preproprotein.

Gene names and symbols associated with SORCS3

  • sortilin related VPS10 domain containing receptor 3 (SORCS3) anticorps
  • zmp:0000001327 (zmp:0000001327) anticorps
  • sortilin related VPS10 domain containing receptor 3 (sorcs3) anticorps
  • sortilin-related VPS10 domain containing receptor 3 (Sorcs3) anticorps
  • 6330404A12Rik anticorps
  • AW045579 anticorps
  • SORCS anticorps

Protein level used designations for SORCS3

sortilin-related VPS10 domain containing receptor 3 , VPS10 domain receptor protein SORCS 3 , VPS10 domain-containing receptor SorCS3-like , VPS10 domain-containing receptor SorCS3 , 6330404A12Rik , VPS10 domain receptor protein SORCS 3 (SORCS3)

GENE ID SPECIES
450723 Pan troglodytes
693500 Macaca mulatta
100408455 Callithrix jacchus
100534837 Danio rerio
100543937 Meleagris gallopavo
100556765 Anolis carolinensis
100607522 Nomascus leucogenys
294043 Rattus norvegicus
22986 Homo sapiens
66673 Mus musculus
423884 Gallus gallus
486879 Canis lupus familiaris
100511162 Sus scrofa
531405 Bos taurus
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