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SNX26 encodes a member of the sorting nexin family. De plus, nous expédions et beaucoup plus de produits pour cette protéine.
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Human Polyclonal SNX26 Primary Antibody pour IHC (p), IHC - ABIN251667
Liu, Nakazawa, Tezuka, Yamamoto: Physical and functional interaction of Fyn tyrosine kinase with a brain-enriched Rho GTPase-activating protein TCGAP. dans The Journal of biological chemistry 2006
Human Polyclonal SNX26 Primary Antibody pour IHC (p), ELISA - ABIN547056
Teasdale, Loci, Houghton, Karlsson, Gleeson: A large family of endosome-localized proteins related to sorting nexin 1. dans The Biochemical journal 2001
ARHGAP33 is associated with brain phenotypes of patients with schizophrenia.
TCGAP interacts with Fyn and is phosphorylated by Fyn, with tyrosine-406 in the GTPase-activating protein (GAP) domain as a major Fyn-mediated phosphorylation site.
Results show that neurite outgrowth multiadaptor RhoGAP protein, NOMA-GAP, plays an essential role downstream of NGF in promoting neurite outgrowth and extension by recruiting SHP2 and activating Cdc42.
ARHGAP33 interacts with SORT1 to cooperatively regulate TrkB trafficking. ARHGAP33 KO mice exhibit reduced expression of synaptic TrkB, impaired dendritic spine development and neuropsychiatric disorder-related behavioural abnormalities.
Results indicate that SNX26 interacts with PSD-95 and regulates formation of dendritic spines.
Cofilin activation during late cortical development depended on NOMA-GAP expression and subsequent inhibition of Cdc42. In utero expression of active cofilin was sufficient to restore postnatal dendritic complexity in NOMA-GAP-deficient animals.
Overexpression of the full-length and C-terminal fragments of TCGAP inhibits insulin-stimulated glucose uptake and GLUT4 translocation.
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. Alternative splice variants encoding different isoforms have been identified in this gene.
neurite outgrowth multiadaptor RhoGAP protein
, rho GTPase-activating protein 33
, rho-type GTPase-activating protein 33
, sorting nexin 26
, sorting nexin-26
, tc10/CDC42 GTPase-activating protein
, TC10/CDC42 GTPase-activating protein