Sp3 Kits ELISA

belongs to a family of Sp1 related genes that encode transcription factors that regulate transcription by binding to consensus GC- and GT-box regulatory elements in target genes. De plus, nous expédions Sp3 Anticorps (81) et et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
6670 Q02447
Anti-Souris  20687 O70494
Anti-Rat  367846  
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  96 Tests 16 to 21 Days

Plus Kits ELISA pour Sp3 partenaires d'interaction

Human Sp3 interaction partners

  1. These findings suggest that the transcription of the b4GalT3 gene is regulated by differential DNA binding of Sp3 and Sp1 in neuroblastoma and lung cancer. The increased expression of b4GalT3 in neuroblastoma may be ascribed to the enhanced expression of Sp3, which is observed for various cancers.

  2. expression of the nearby cyclindependent kinase inhibitor 1C (CDKN1C) gene was revealed to be upregulated after SP3 knockdown in cells that possessed non-risk alleles. This suggests that CDKN1C is potentially one of the functional targets of SNP rs163184, which modulates the binding activity of the locus for Sp3 and Lsd1/Kdm1a

  3. Sp1, Sp3 and Sp4 are non-oncogene addiction (NOA) genes and are attractive drug targets for individual and combined cancer chemotherapies.

  4. High SP3 expression is associated with hepatocellular carcinoma.

  5. we established a new regulatory model of COL1A1 regulation by HIF-1, and bring out its relationship with Sp3 transcription factor. In a fundamental level, these findings give insights in the mechanisms controlling COL1A1 gene expression.

  6. Data indicate that the antitumor activity of trefoil factor 2 (TFF2) is mediated by an interaction with the transcription factor Sp3 (Sp3) in gastric cancer cells.

  7. demonstrate that a 186bp region is the minimal essential region and that Sp3-GC1 binding is essential to the basal expression of KLF5

  8. Sp1 and Sp3 are not only essential for the basal transcription of the ek1 gene, their accessibility to the target site on the ek1 promoter is regulated by histone protein modification in a cell line dependent manner.

  9. Human SP1 and SP3 transcription factors regulate MALAT1 expression in hepatocellular carcinoma.

  10. result indicated that promoter binding by Sp1/Sp3 was essential, but not a limiting step, for hTERT transcription

  11. Sp3 was found to be a major regulator of BNIP3 in prostate cancer.

  12. stimulates CCR7 expression during the course of dendritic cell maturation

  13. O-GlcNAc modification of Sp3 and Sp4, but not Sp2 transcription factors negatively regulates their transcriptional activities.

  14. characterized two evolutionary highly conserved cis-regulatory modules (CRMs) within the proximal promoter each composed of one binding site for the transcription factors SP1 and SP3 as well as for the nuclear transcription factor Y

  15. These results suggest that XT-1 expression is refractory to the disease process and to inhibition by inflammatory cytokines and that signaling through AP-1, Sp1, and Sp3 is important in the maintenance of XT-1 levels in NP cells.

  16. A novel GC-rich element (GRE) spanning -101/-66 sufficient for VEGFR3 transcription and activated by Sp1 and Sp3, respectively, was identified.

  17. Results demonstrate that Sp1 and Sp3 transcription factors are the primary determinants for activating basal transcription of the ABCG2 gene and play an important role in maintaining the side population phenotype of lung cancer cells.

  18. Sp1 and Sp3 are functionally involved as transcriptional integrators regulating the basal expression of the derived microsomal epoxide hydrolase E1b variant transcript.

  19. This study showed that SP1, SP3 and SP4 protein levels inversely correlated with negative symptoms in the cerebellum.

  20. Chromosome 2q31.1 is located between the genes that code for Sp3 transcription factor, which regulates expression of genes linked to glomerular function and the pathogenesis of nephropathy, and the CDCA7 transcription factor.

Mouse (Murine) Sp3 interaction partners

  1. Sp3 interacts with the STING promoter and activates the basal transcription of the STING gene.

  2. This resulted in Sp1 displacement from the promoter and binding of Sp3 to it, leading to p300 recruitment and histone acetylation, activating transcription. This is the first study addressing the mechanisms of physiological TLR5 expression in the intestine. Additionally, a novel insight is gained into Sp1/Sp3-mediated gene regulation that may apply to other genes

  3. Sp3 binds and activates the FGFR4 promoter.

  4. Dp71 expression in hepatic cells is carried out, in part, by YY1-, Sp1- and Sp3-mediated transcription from the Dp71 promoter.

  5. Our results unveil strikingly different recruitment mechanisms of Sp1/Sp2/Sp3 transcription factor members uncovering an unexpected layer of complexity in their binding to chromatin in vivo.

  6. Sp1/Sp3 transcription factors have roles in regulating hallmarks of megakaryocyte maturation and platelet formation and function

  7. Sp1/3 transcription factors trigger Mina expression through additive activity targeted to a cluster of four Sp1/3 binding sites forming the P1 promoter.

  8. an interplay between Sp1 and Sp3 as a mechanism involved in the control of Fiat gene expression in osteoblasts.

  9. Oct-6 and Oct-11 contribute to the regulation of loricrin gene transcription via interaction with AP-1 factors and Sp1/Sp3.

  10. inhibition of FGF-10 by inflammatory signaling involves the NF-kappaB-dependent interactions between RELA, SP3, and the Fgf-10 promoter.

  11. Three GC boxes within the proximal promoter of the murine pyruvate carboxylase gene bind Sp1/Sp3

  12. Results suggest that Sp3 and YY1 recruit general transcription factors and facilitate the assembly of a preinitiation complex.

  13. These results establish SUMO conjugation to Sp3 as a molecular beacon for the assembly of repression machineries to maintain tissue-specific transcriptional gene silencing.

  14. LIF and IGF-I, thus, have cooperative and distinct tissue functions during development. Their essential role in bone ossification apparently involves Sp3, and in lung maturation Sp3 together with TTF-1.

  15. Sp3 transcription factor-binding site within the Ren-1 enhancer contributes to the enhancer activity

  16. Sp3-/- cells were able to repopulate the B- and T-lymphoid compartment, albeit with reduced efficiency. In contrast, Sp3-/- cells showed no significant engraftment in the erythroid and myeloid lineages.

  17. Sp3 has a role in controlling fgl2 expression in endothelial cells

  18. we have shown that Sp1 and Sp3 bind to cis-regulatory elements located in the AP-2gamma promoter proximal region and contribute to basal promoter activity.

  19. MBD2 and Sp3 are involved in transcriptional repression of the mouse delta-opioid receptor gene

  20. two Sp1/Sp3 sites in the proximal promoter of benzodiazepine receptor are important for basal activity in all cell lines tested and steroidogenic MA-10 and Y1 cells use different areas of the promoter compared with nonsteroidogenic NIH-3T3 cells.

Cow (Bovine) Sp3 interaction partners

  1. These results demonstrate that the single nucleotide polymorphism alters the bovine FASN promoter activity in vitro and the Sp1/Sp3 binding ability of the sequence.

Sp3 profil antigène

Antigen Summary

This gene belongs to a family of Sp1 related genes that encode transcription factors that regulate transcription by binding to consensus GC- and GT-box regulatory elements in target genes. This protein contains a zinc finger DNA-binding domain and several transactivation domains, and has been reported to function as a bifunctional transcription factor that either stimulates or represses the transcription of numerous genes. Transcript variants encoding different isoforms have been described for this gene, and one has been reported to initiate translation from a non-AUG (AUA) start codon. Additional isoforms, resulting from the use of alternate downstream translation initiation sites, have also been noted. A related pseudogene has been identified on chromosome 13.

Gene names and symbols associated with Sp3 Kits ELISA

  • Sp3 transcription factor (SP3) anticorps
  • trans-acting transcription factor 3 (Sp3) anticorps
  • Sp3 transcription factor (Sp3) anticorps
  • sp3a transcription factor (sp3a) anticorps
  • Sp3 transcription factor S homeolog (sp3.S) anticorps
  • D130027J01Rik anticorps
  • sp3 anticorps
  • SPR2 anticorps
  • zgc:162922 anticorps

Protein level used designations for Sp3 Kits ELISA

GC-binding transcription factor Sp3 , specificity protein 3 , transcription factor Sp3 , trans-acting transcription factor 3 , Sp3 transcription factor , sp3 transcription factor

6670 Homo sapiens
20687 Mus musculus
367846 Rattus norvegicus
395302 Gallus gallus
488405 Canis lupus familiaris
540766 Bos taurus
558652 Danio rerio
100037013 Xenopus laevis
100064317 Equus caballus
100729306 Cavia porcellus
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