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The protein encoded by SPECC1 belongs to the cytospin-A family. De plus, nous expédions Sperm Antigen with Calponin Homology and Coiled-Coil Domains 1 Protéines (6) et et beaucoup plus de produits pour cette protéine.
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Human Polyclonal SPECC1 Primary Antibody pour ICC, IF - ABIN151956
Dagostino, Giordano: NSP 5a3a: a potential novel cancer target in head and neck carcinoma. dans Oncotarget 2011
Show all 2 Pubmed References
Polyclonal SPECC1 Primary Antibody pour WB - ABIN540839
Sang, Fath, Giordano: A gene highly expressed in tumor cells encodes novel structure proteins. dans Oncogene 2004
NSP (Montrer RTN1 Anticorps) 5a3a induces apoptosis in Head and Neck cell line HN30 through p73 (Montrer TP73 Anticorps)-DAXX (Montrer DAXX Anticorps) and TRAF2 (Montrer TRAF2 Anticorps)-TRADD (Montrer TRADD Anticorps).
NSP (Montrer RTN1 Anticorps) 5a3a's novel interaction with B23 (Montrer NPM1 Anticorps) and ribonuclear protein hnRNP-L (Montrer HNRNPL Anticorps) implicates NSP (Montrer RTN1 Anticorps) 5a3a in cellular processes such as ribosome biogenesis and rRNA transcription .
Loss of NSP (Montrer RTN1 Anticorps) 5a3a is associated with head and neck carcinoma.
PCR and fluoresecne in situ hybridization shows that HCMOGT-1 is a novel fusion partner to PDGFRB (Montrer PDGFRB Anticorps) in juvenile myelomonocytic leukemia with t(5;17)(q33;p11.2).
Specc1 mutant showes profound and specific delay in avoidance learning.
The protein encoded by this gene belongs to the cytospin-A family. It is localized in the nucleus, and highly expressed in testis and some cancer cell lines. A chromosomal translocation involving this gene and platelet-derived growth factor receptor, beta gene (PDGFRB) may be a cause of juvenile myelomonocytic leukemia. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
, cytokinesis and spindle organization B
, nuclear structure protein 5
, sperm antigen HCMOGT-1
, sperm antigen with calponin-like and coiled coil domains 1
, structure protein NSP5a3a
, structure protein NSP5a3b
, structure protein NSP5b3a
, structure protein NSP5b3b
, cytospin B
, spectrin domain with coiled-coils 1
, sperm antigen with calponin homology and coiled-coil domains 1