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The lysosphingolipid sphingosine 1-phosphate (S1P) regulates cell proliferation, apoptosis, motility, and neurite retraction. De plus, nous expédions S1PR5 Anticorps (128) et S1PR5 Protéines (4) et beaucoup plus de produits pour cette protéine.
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Reduced DNA methylation may underlie the increased expression of the S1PR5 gene in alveolar macrophages and associated defective efferocytosis in COPD (Montrer ARCN1 Kits ELISA).
Data indicate that the mitotic kinase Polo-like kinase 1 (PLK1 (Montrer PLK1 Kits ELISA)) was an important effector of S1P-S1P5 signaling, and a new function of the SphK1 (Montrer SPHK1 Kits ELISA)-S1P pathway specifically in the control of mitosis in HeLa cells.
TGF-beta2 (Montrer TGFB2 Kits ELISA) dependent upregulation of S1P5 is required for the induction of pro-fibrotic CTGF (Montrer CTGF Kits ELISA) by TGF-beta (Montrer TGFB1 Kits ELISA) in mesangial cells.
This report is the first to demonstrate a reduction in S1P5 in multiple sclerosis lesions, which parallels that of myelin loss.
Data show that sphingosine kinase SphK1 (Montrer SPHK1 Kits ELISA) and sphingosine-1-phosphate (S1P) receptors S1P1 (Montrer S1PR1 Kits ELISA), S1P2 (Montrer S1PR2 Kits ELISA), S1P3 (Montrer S1PR3 Kits ELISA), and S1P5 were expressed from primary, up to recurrent and secondary glioblastomas, with sphingosine kinase SphK2 (Montrer SPHK2 Kits ELISA) levels were highest in primary tumors.
Edg-5 (Montrer S1PR2 Kits ELISA) receptor in brain endothelial cells contributes to optimal barrier formation and maintenance of immune quiescence of the barrier endothelium.
The decreased expression level of S1PR5 on NK cells is associated with graft versus host disease occurrence after allogeneic hematopoietic stem cell transplantation.
The molecular identity, functional properties, and expression profile of the S1P5 (Edg-8) receptor have been characterized.
FTY720 induces time-dependent modulation of S1P receptors on human OPCs with consequent functional responses that are directly relevant for the remyelination process.
The centrosomal sphingosine-1-phosphate receptor 5 might function as an intracellular target of sphingosine-1-phosphate linked to regulation of mitosis.
Coordinated changes in CXCR4 (Montrer CXCR4 Kits ELISA) and S1P5 responsiveness govern NK-cell trafficking.
Fndings suggest that S1P (Montrer S1PR1 Kits ELISA)(5) may mediate the effects of S1P (Montrer S1PR1 Kits ELISA) in terms of regulating ERK-1 (Montrer MAPK3 Kits ELISA)/2 signaling in ES cells.
Edg8/S1P5 activation on oligodendroglial cells modulates two distinct functional pathways mediating either process retraction or cell survival and that these effects depend on the developmental stage of the cell.
Sphingosine 1-phosphate receptors regulate chemokine (Montrer CCL1 Kits ELISA)-driven transendothelial migration of lymph node but not splenic T cells.
KLF2 (Montrer KLF2 Kits ELISA) regulates T cell homeostasis at least partly by controlling CD62L (Montrer SELL Kits ELISA) and S1P1 (Montrer S1PR1 Kits ELISA) expression, and therefore T cell egress from the thymus and circulation in the periphery.
These findings identify S1P5 as a T-bet-induced gene that is required for natural killer cell egress from lymph nodes and bone marrow.
The lysosphingolipid sphingosine 1-phosphate (S1P) regulates cell proliferation, apoptosis, motility, and neurite retraction. Its actions may be both intracellular as a second messenger and extracellular as a receptor ligand. S1P and the structurally related lysolipid mediator lysophosphatidic acid (LPA) signal cells through a set of G protein-coupled receptors known as EDG receptors. Some EDG receptors (e.g., EDG1\; MIM 601974) are S1P receptors\; others (e.g., EDG2\; MIM 602282) are LPA receptors.
S1P receptor 5
, S1P receptor Edg-8
, endothelial differentiation G-protein-coupled receptor 8
, endothelial differentiation, sphingolipid G-protein-coupled receptor, 8
, sphingosine 1-phosphate receptor 5
, sphingosine 1-phosphate receptor EDG8
, sphingosine 1-phosphate receptor Edg-8
, nerve growth factor-regulated G-protein-coupled receptor 1
, lysophospholipid receptor B4
, sphingosine-1-phosphate receptor LPB4
, Sphingosine 1-phosphate receptor Edg-8
, endothelial differentiation, sphingolipid G-protein-coupled receptor 8