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SREK1 encodes a member of a family of serine/arginine-rich (SR) splicing proteins containing RNA recognition motif (RRM) domains. De plus, nous expédions Splicing Regulatory Glutamine/lysine-Rich Protein 1 Anticorps (20) et Splicing Regulatory Glutamine/lysine-Rich Protein 1 Kits (6) et beaucoup plus de produits pour cette protéine.
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From among the 500 splicing events exhibiting altered splicing under these conditions, the splicing of c-Jun (Montrer JUN Protéines) and IkappaBbeta (Montrer NFKBIB Protéines) were validated as being regulated by SRrp86 resulting in altered regulation of their downstream targets.
SRrp86 can activate SRp20 (Montrer SRSF3 Protéines) and repress SC35 (Montrer SRSF2 Protéines) in a dose-dependent manner both in vitro and in vivo
the unique glutamic acid-lysine domain of SRrp86 plays a modulatory role controlling serine-arginine domain function
p18SRP (Montrer SFRS12IP1 Protéines) is a lysine-rich zinc finger domain-containing protein that interacts with the serine-arginine-rich splicing regulatory protein SRrp86; it is downregulated in brain of Alzheimer disease patients.
This gene encodes a member of a family of serine/arginine-rich (SR) splicing proteins containing RNA recognition motif (RRM) domains. The encoded protein interacts with other SR proteins to modulate splice site selection. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
serine-arginine-rich splicing regulatory protein 508
, serine/arginine-rich-splicing regulatory protein 86
, splicing factor, arginine/serine-rich 12
, splicing regulatory protein 508
, SR-related protein of 86 kDa
, serine-arginine-rich splicing regulatory protein 86
, serine-arginine-rich-splicing regulatory protein 86
, serine/arginine-rich splicing factor 12
, splicing regulatory glutamine/lysine-rich protein 1