Split Hand/foot Malformation (Ectrodactyly) Type 1 (SHFM1) Kits ELISA

The product of SHFM1 has been localized within the split hand/split foot malformation locus SHFM1 at chromosome 7. De plus, nous expédions SHFM1 Anticorps (43) et SHFM1 Protéines (7) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
SHFM1 7979 P60896
SHFM1 20422 P60897
Anti-Rat SHFM1 SHFM1 680532  
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Top SHFM1 Kits ELISA sur anticorps-enligne.fr

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Catalogue No. Reactivité Sensibilité Gamme Images Quantité Fournisseur Livraison Prix Détails
Humain < 0.188 ng/mL 0.313 ng/mL - 20 ng/mL   96 Tests Connectez-vous pour afficher 11 to 18 Days
$810.17
Détails
Souris < 0.094 ng/mL 0.156 ng/mL - 10 ng/mL   96 Tests Connectez-vous pour afficher 11 to 18 Days
$810.17
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Boeuf (Vache)
  96 Tests Connectez-vous pour afficher 15 to 18 Days
$1,029.60
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Plus Kits ELISA pour SHFM1 partenaires d'interaction

Human Split Hand/foot Malformation (Ectrodactyly) Type 1 (SHFM1) interaction partners

  1. Promoter methylation plays a role in modulating DSS1 gene expression. Promoter hypomethylation is a frequent event in melanoma and squamous cell carcinoma and is closely linked to poor prognosis.

  2. DSS1 is a multifunctional and intrinsically disordered protein. (Review)

  3. three phenotypic subregions within the SHFM1 locus link both size and genomic position of the chromosomal aberrations to the clinical variability seen in SHFM1 patients

  4. SHFM1 confers cell cycle progression and resistance to p53 (Montrer TP53 Kits ELISA) stabilizing drugs in gastric cancer cells.

  5. by targeting RPA (Montrer RPA1 Kits ELISA) and mimicking DNA, DSS1 functions with BRCA2 (Montrer BRCA2 Kits ELISA) in a two-component homologous recombination mediator complex in genome maintenance and tumor suppression

  6. Breast cancers with high DSS1 expression have worse prognosis and shorter relapse-free survival times.

  7. Mutation screening of the SHFM1 gene in familial breast/ovarian cancer cases.

  8. DSS1 protein is critically involved in the maintenance of the transformed phenotype in cervical cancer cells, and that it might be a specific, robust and reliable marker for early detection, diagnosis and trea (Montrer TREH Kits ELISA)

  9. DSS1 has a role in homologous recombinational repair in human cells

  10. p63 (Montrer RPE65 Kits ELISA) binds to an enhancer element in the SHFM1 locus and this element controls expression of DLX6 and DLX5 (Montrer DLX5 Kits ELISA) which are important for limb development.

Mouse (Murine) Split Hand/foot Malformation (Ectrodactyly) Type 1 (SHFM1) interaction partners

  1. 3.1 angstrom crystal structure of approximately 90-kilodalton BRCA2 domain bound to DSS1, which reveals three oligonucleotide-binding (OB) folds and a helix-turn-helix (HTH) motif

SHFM1 profil antigène

Antigen Summary

The product of this gene has been localized within the split hand/split foot malformation locus SHFM1 at chromosome 7. It has been proposed to be a candidate gene for the autosomal dominant form of the heterogeneous limb developmental disorder split hand/split foot malformation type 1. In addition, it has been shown to directly interact with BRCA2. It also may play a role in the completion of the cell cycle.

Gene names and symbols associated with SHFM1

  • SEM1, 26S proteasome complex subunit (SEM1) anticorps
  • SEM1, 26S proteasome complex subunit (Sem1) anticorps
  • SEM1, 26S proteasome complex subunit S homeolog (sem1.S) anticorps
  • dss1 anticorps
  • ecd anticorps
  • sem1 anticorps
  • shfd1 anticorps
  • shfdg1 anticorps
  • Shfg anticorps
  • shfm1 anticorps
  • shfm1.S anticorps
  • shsf1 anticorps

Protein level used designations for SHFM1

26S proteasome complex subunit DSS1 , deleted in split hand/split foot protein 1 , deleted in split-hand/split-foot 1 , split hand/foot deleted protein 1 , split hand/foot malformation type 1 protein , candidate for split hand/foot malformation type 1 , 26 proteasome complex subunit DSS1 , split hand/foot malformation type 1 protein homolog , split hand/foot malformation (ectrodactyly) type 1 , deleted in split hand/split foot protein 1 homolog , split hand/foot deleted gene 1 , split hand/foot deleted protein 1 homolog , 26S proteasome complex subunit SEM1 , split hand/foot malformation (ectrodactyly) type 1 S homeolog

GENE ID SPECIES
7979 Homo sapiens
608719 Canis lupus familiaris
698349 Macaca mulatta
747549 Pan troglodytes
767981 Bos taurus
772237 Gallus gallus
100038817 Taeniopygia guttata
20422 Mus musculus
680532 Rattus norvegicus
100155621 Sus scrofa
447126 Xenopus laevis
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