anti-Stathmin-Like 2 (STMN2) Anticorps

STMN2 encodes a member of the stathmin family of phosphoproteins. De plus, nous expédions Stathmin-Like 2 Protéines (10) et Stathmin-Like 2 Kits (2) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
STMN2 11075 Q93045
STMN2 20257 P55821
STMN2 84510 P21818
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Showing 10 out of 122 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Livraison Prix Détails
Souris Chèvre Inconjugué ELISA, WB Antibody (0.5µg/ml) staining of Mouse Foetal Brain lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg 6 to 7 Days
Poulet Lapin Inconjugué WB Western blot analysis of STMN2 expression in SHSY5Y (A), NIH3T3 (B), A549 (C), rat brain (D) whole cell lysates. 200 μL 13 to 14 Days
Humain Lapin Inconjugué ELISA, IHC (p), WB Immunohistochemistry (IHC) analysis of paraffin-embedded Rat Brain, antibody was diluted at 1:100. 100 μL Disponible
Humain Lapin Inconjugué ICC, IF, IHC (p), WB IHC-P Image STMN2 antibody detects STMN2 protein at cytoplasm on human liver carcinoma by immunohistochemical analysis. Sample: Paraffin-embedded liver carcinoma. STMN2 antibody , dilution: 1:250. ICC/IF Image Immunofluorescence analysis of methanol-fixed A549, using STMN2, antibody at 1:500 dilution. 100 μL 3 to 4 Days
Humain Lapin Inconjugué IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat brain labeled with Rabbit Anti STMN2/SCG10 Polyclonal Antibody, Unconjugated (ABIN703616) at 1:200 followed by conjugation to the secondary antibody and DAB staining Antigen: 0.2 µg/100 µL  Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000;  Secondary: HRP conjugated Goat-Anti-Rabbit IgG at 1: 5000;  TMB staining;  Read the data in MicroplateReader by 450 100 μL 3 to 7 Days
Poulet Chèvre Inconjugué ELISA, IHC, IHC (p), WB Human Brain, Cortex (formalin-fixed, paraffin-embedded) stained with STMN2 antibody ABIN461978 at 5 ug/ml followed by biotinylated anti-goat IgG secondary antibody ABIN481715, alkaline phosphatase-streptavidin and chromogen. Human Small Intestine, Myenteric Plexus (formalin-fixed, paraffin-embedded) stained with STMN2 antibody ABIN461978 at 5 ug/ml followed by biotinylated anti-goat IgG secondary antibody ABIN481715, alkaline phosphatase-streptavidin and chromogen. 50 μg 11 to 14 Days
Humain Lapin Inconjugué ELISA, WB Western blot analysis STMN2 (Phospho-Ser73) using PMA treated Jurkat whole cell lysates 100 μL 11 to 12 Days
Humain Lapin Inconjugué ELISA, IHC, WB Western blot analysis STMN2 using mouse liver lysates ABIN6279860 at 1/100 staining Mouse colon tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22¡ãC. An HRP conjugated goat anti-rabbit antibody was used as the secondary 100 μL 11 to 12 Days
Boeuf (Vache) Chèvre Inconjugué WB   0.1 mg 4 to 8 Days
Humain Lapin Inconjugué EIA, WB Western blot analysis of Stathmin-2 / STMN2 (C-term) in Jurkat cell line lysates (35ug/lane). This demonstrates the STMN2 antibody detected the STMN2 protein (arrow). 0.4 mL 6 to 8 Days

anti-Stathmin-Like 2 Anticorps mieux référencés

  1. Cow (Bovine) Polyclonal STMN2 Primary Antibody pour ICC, IF - ABIN4356489 : Shin, Cho, Beirowski, Milbrandt, Cavalli, DiAntonio: Dual leucine zipper kinase is required for retrograde injury signaling and axonal regeneration. dans Neuron 2012 (PubMed)
    Show all 18 Pubmed References

  2. Mammalian Monoclonal STMN2 Primary Antibody pour ISt, IHC - ABIN1304947 : Sobczak, Debowska, Blazejczyk, Kreutz, Kuznicki, Wojda: Calmyrin1 binds to SCG10 protein (stathmin2) to modulate neurite outgrowth. dans Biochimica et biophysica acta 2011 (PubMed)
    Show all 5 Pubmed References

  3. Dog (Canine) Polyclonal STMN2 Primary Antibody pour ELISA, WB - ABIN546837 : Bahn, Mimmack, Ryan, Caldwell, Jauniaux, Starkey, Svendsen, Emson: Neuronal target genes of the neuron-restrictive silencer factor in neurospheres derived from fetuses with Down's syndrome: a gene expression study. dans Lancet 2002 (PubMed)

Plus d’anticorps contre Stathmin-Like 2 partenaires d’interaction

Zebrafish Stathmin-Like 2 (STMN2) interaction partners

  1. Zebrafish studies further demonstrated an epistatic interaction between KBP and SCG10 in vivo.

  2. Results provide a starting point for future studies that will investigate the in vivo function of SCG10 orthologues in zebrafish neural development.

Human Stathmin-Like 2 (STMN2) interaction partners

  1. expression of STMN2, which encodes a microtubule regulator, declined after TDP-43 knockdown and TDP-43 mislocalization as well as in patient-specific motor neurons and postmortem patient spinal cord. STMN2 loss upon reduced TDP-43 function was due to altered splicing, which is functionally important, as we show STMN2 is necessary for normal axonal outgrowth and regeneration.

  2. premature polyadenylation-mediated reduction in stathmin-2 is a hallmark of ALS-FTD that functionally links reduced nuclear TDP-43 function to enhanced neuronal vulnerability.

  3. RARB and STMN2 polymorphisms were not associated with sporadic CJD in the Korean population.

  4. PAK4-SCG10 signaling occurs in gastric cancer cell invasion.

  5. STMN and SCG10 are similarly targeted by JNK but there are clear differences in JNK recognition and phosphorylation of the closely related family member, SCLIP.

  6. CaMy1 via SCG10 couples Ca(2+) signals with the dynamics of microtubules during neuronal outgrowth in the developing brain.

  7. SCG10 is upregulated in the IKAP/Elp1-deficient familial dysautonomia cerebrum lending support to the concept that SCG10 elevation can alter the microtubule organization and dynamics

  8. Overexpression of SCG10 is associated with Liver Fibrosis.

  9. RGS6 interacts with this protein and promotes neuronal differentiation; role of the G gamma subunit-like (GGL) domain of RGS6

  10. STMN2 is required for maintaining the anchorage-independent growth state of beta-catenin/TCF-activated hepatoma cells

  11. activity at opposite microtubule ends may play role role in regulating growth cone microtubules; ability to promote plus end growth may facilitate microtubule extension; ability to destabilize minus ends may provide tubulin for net plus end elongation

  12. Review proposes a model reconciling the microtubule regulatory properties of superior cervical ganglion protein 10 with its role as a c-Jun N-terminal kinase 1 (JNK1) effector of regeneration.

  13. BRI3 associates with SCG10 and attenuates NGF-induced neurite outgrowth in PC12 cells.

  14. SCLIP and SCG10 were colocalized to the Golgi apparatus of chromaffin cells in vivo and shared localization with CHGA as it transited the Golgi.

  15. STMN2 appears a novel marker of osteogenesis and osteoblast per se, that could play a role in the regulation of the adipocyte/osteoblast balance.

  16. SCG10 acts as an effector downstream of Rnd1 to regulate axon extensions by modulating microtubule organization.

Mouse (Murine) Stathmin-Like 2 (STMN2) interaction partners

  1. autophagy induction stabilized microtubules by degrading SCG10, a microtubule disassembly protein in neurons. In mice with spinal cord injury, local administration of a specific autophagy-inducing peptide, Tat-beclin1, to lesion sites markedly attenuated axonal retraction of spinal dorsal column axons and cortical spinal tract and promoted regeneration of descending axons following long-term observation

  2. SCG10 promotes non-amyloidogenic processing of amyloid precursor protein by facilitating its trafficking to the cell surface.

  3. This study demonstrated that axonal injury induces a dynamic regulation of SCG10 protein levels with selective accumulation in proximal axon segments.

  4. JNK phosphorylation targets SCG10 for degradation.

  5. SCG10 is not directly implicated in Hirschsprung diseased evelopment

  6. the Rarb region of Mmu14 and Stmn2, but not Cr1 or Clu or Picalm have roles in prion disease

  7. These findings indicate that the phosphorylation of SCG10 by JNK1 is a fundamental mechanism that governs the transition from the multipolar stage and the rate of neuronal cell movement during cortical development.

  8. KBP binds exclusively to microtubule associated or related proteins, specifically SCG10.

Stathmin-Like 2 (STMN2) profil antigène

Profil protéine

This gene encodes a member of the stathmin family of phosphoproteins. Stathmin proteins function in microtubule dynamics and signal transduction. The encoded protein plays a regulatory role in neuronal growth and is also thought to be involved in osteogenesis. Reductions in the expression of this gene have been associated with Down's syndrome and Alzheimer's disease. Alternatively spliced transcript variants have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome 6.

Gene names and symbols associated with anti-Stathmin-Like 2 (STMN2) Anticorps

  • stathmin 2 (stmn2) anticorps
  • stathmin 2 (STMN2) anticorps
  • stathmin 2b (stmn2b) anticorps
  • stathmin-2-like (LOC100226401) anticorps
  • stathmin-2 (Tsp_05441) anticorps
  • stathmin-like 2 (Stmn2) anticorps
  • stathmin 2 (Stmn2) anticorps
  • AI159727 anticorps
  • MGC89837 anticorps
  • Scg10 anticorps
  • Scgn10 anticorps
  • Stmb2 anticorps
  • stmn2 anticorps
  • stmn2c anticorps
  • zgc:110132 anticorps

Protein level used designations for anti-Stathmin-Like 2 (STMN2) Anticorps

stathmin-like 2 , stathmin-like 2c , SCG10a , stathmin-2 , superiorcervical ganglia, neural specific 10 , neuron-specific growth-associated protein , neuronal growth-associated protein (silencer element) , superior cervical ganglia, neural specific 10 , superior cervical ganglion-10 protein , stathmin 2

448716 Xenopus (Silurana) tropicalis
464247 Pan troglodytes
100003563 Danio rerio
100156768 Sus scrofa
100226401 Taeniopygia guttata
10913268 Trichinella spiralis
11075 Homo sapiens
20257 Mus musculus
84510 Rattus norvegicus
477918 Canis lupus familiaris
534991 Bos taurus
396095 Gallus gallus
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