anti-Stromal Interaction Molecule 2 (Stim2) Anticorps

Stim2 is a member of the stromal interaction molecule (STIM) family and likely arose, along with related family member STIM1, from a common ancestral gene. De plus, nous expédions Stim2 Protéines (8) et et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
Stim2 57620 Q9P246
Stim2 116873 P83093
Stim2 117087  
Comment commander chez anticorps-enligne
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Commandez enligne
  • orders@anticorps-enligne.fr

Top anti-Stim2 Anticorps sur anticorps-enligne.fr

Showing 10 out of 72 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB Host: Rabbit Target Name: Stim2 Sample Type: Mouse Pancreas lysates Antibody Dilution: 1.0ug/ml 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Humain Lapin Inconjugué EIA, IHC (p), WB Formalin fixed, paraffin embedded human kidney tissue stained with STIM2 Antibody (N-term) followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of STIM2 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. Western blot analysis of STIM2 Antibody (N-term) in UM cell line lysates (35ug/lane). This demonstrates the STIM2 antibody detected the STIM2 protein (arrow 0.4 mL Connectez-vous pour afficher 6 to 8 Days
$390.50
Détails
Humain Lapin Inconjugué IHC (p), WB STIM2 Antibody (N-term) (ABIN656476) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL Connectez-vous pour afficher 10 to 11 Days
$335.50
Détails
Humain Lapin Inconjugué WB 0.1 mg Connectez-vous pour afficher 6 to 8 Days
$379.50
Détails
Humain Lapin Inconjugué EIA, IHC (p), WB Human Liver (formalin-fixed, paraffin-embedded) stained with STIM2at 5 µg/ml followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. Human Pancreas (formalin-fixed, paraffin-embedded) stained with STIM2at 5 µg/ml followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. 50 μg Connectez-vous pour afficher 6 to 8 Days
$390.50
Détails
Humain Lapin Inconjugué EIA, IHC (p), WB   0.1 mg Connectez-vous pour afficher 8 to 11 Days
$474.10
Détails
Humain Lapin Inconjugué EIA, IHC (p), WB   0.1 mg Connectez-vous pour afficher Disponible
$474.10
Détails
Humain Lapin Inconjugué IHC, ELISA, WB   100 μg Connectez-vous pour afficher 15 to 19 Days
$523.71
Détails
Humain Lapin Inconjugué IHC, ELISA, WB   100 μg Connectez-vous pour afficher 15 to 19 Days
$523.71
Détails
Humain Lapin Inconjugué IHC, IHC (p), WB Human Brain, Cortex (formalin-fixed, paraffin-embedded) stained with STIM2 antibody ABIN213834 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Anti-STIM2 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. 50 μg Connectez-vous pour afficher 11 to 14 Days
$484.00
Détails

anti-Stim2 Anticorps mieux référencés

  1. Human Polyclonal Stim2 Primary Antibody pour IHC, ELISA - ABIN1003212 : Luik, Lewis: New insights into the molecular mechanisms of store-operated Ca2+ signaling in T cells. dans Trends in molecular medicine 2007 (PubMed)
    Show all 4 Pubmed References

  2. Human Polyclonal Stim2 Primary Antibody pour IHC, ELISA - ABIN1003213 : Spassova, Soboloff, He, Xu, Dziadek, Gill: STIM1 has a plasma membrane role in the activation of store-operated Ca(2+) channels. dans Proceedings of the National Academy of Sciences of the United States of America 2006 (PubMed)
    Show all 4 Pubmed References

Plus d’anticorps contre Stim2 partenaires d’interaction

Human Stromal Interaction Molecule 2 (Stim2) interaction partners

  1. Stim2 deletion reduced SOCE by more than 90% in NIH 3T3 cells and abolishes STIM1 (Montrer STIM1 Anticorps) translocation to plasma membrane-associated ER membrane junctions.

  2. With STIM2 being essential for life, but apparently not for development, newly available data demonstrate a complex and still intriguing behaviour that this review summarizes, updating current knowledge of STIM2 function [review]

  3. The STIM2 protein play important roles in TGF-beta (Montrer TGFB1 Anticorps)-induced EMT (Montrer ITK Anticorps) and these effects are related to both store-operated calcium entry and non-store-operated calcium entry.

  4. What is less clear is how the spatial and temporal spread of intracellular Ca(2 (Montrer CA2 Anticorps)+) is shaped and regulated by differential expression of the individual SOCE genes and their splice variants, their heteromeric combinations and pre- and posttranslational modifications. This review focuses on principle mechanisms regulating expression, splicing, and targeting of Ca(2 (Montrer CA2 Anticorps)+) release-activated Ca(2 (Montrer CA2 Anticorps)+) (CRAC) channels.

  5. While STIM1 (Montrer STIM1 Anticorps) is a full Orai1 (Montrer ORAI1 Anticorps)-agonist, leucine-replacement of this crucial residue in STIM2 endows it with partial agonist properties, which may be critical for limiting Orai1 (Montrer ORAI1 Anticorps) activation stemming from its enhanced sensitivity to store-depletion

  6. STIM2.1 cannot activate Orai1 (Montrer ORAI1 Anticorps) due to splicing in residues within the channel-activating domain (CAD (Montrer CAD Anticorps)). STIM2.1 confers a calcium dependent dominant-negative function on both STIM1 (Montrer STIM1 Anticorps) and STIM2 (STIM2.2). Affinity of the STIM2.1 calmodulin binding site within the CAD (Montrer CAD Anticorps) domain is increased compared to STIM2.2.

  7. STIM2 enhances receptor-stimulated Ca(2 (Montrer CA2 Anticorps)) signaling by promoting recruitment of STIM1 (Montrer STIM1 Anticorps) to the endoplasmic reticulum-plasma membrane junctions.

  8. STIM2beta does not by itself strongly bind Orai1 (Montrer ORAI1 Anticorps), it is recruited to Orai1 (Montrer ORAI1 Anticorps) channels by forming heterodimers with other STIM isoforms.

  9. Imin channels are regulated by STIM2, TRPC3 (Montrer TRPC3 Anticorps)-containing INS (Montrer INS Anticorps) channels are induced by STIM1 (Montrer STIM1 Anticorps), and TRPC1 (Montrer TRPC1 Anticorps)-composed Imax channels are activated by both STIM1 (Montrer STIM1 Anticorps) and STIM2.

  10. The higher amplitude of store-operated Ca2 (Montrer CA2 Anticorps)+ entry was associated to the over-expression for Stim2, Orai2 (Montrer ORAI2 Anticorps)-3, and TRPC1 (Montrer TRPC1 Anticorps) while Stim2 levels remained constant and Stim1 (Montrer STIM1 Anticorps), Orai1 (Montrer ORAI1 Anticorps), Orai3 (Montrer ORAI3 Anticorps), TRPC1 (Montrer TRPC1 Anticorps) and TRPC4 (Montrer TRPC4 Anticorps) proteins were over-expressed in primary myelofibrosis.

Mouse (Murine) Stromal Interaction Molecule 2 (Stim2) interaction partners

  1. Stim1 (Montrer STIM1 Anticorps) and Stim2 deficient B cells show an accelerated pace of affinity maturation but do not have dramatically impaired antibody production to T-independent antigen immunization

  2. We found that STIM2 is required for the stable expression of both LTP (Montrer SCP2 Anticorps) and LTD at CA3 (Montrer CA3 Anticorps)-CA1 (Montrer CA1 Anticorps) hippocampal synapses. Altered plasticity in Stim2 cKO mice is associated with subtle alterations in the shape and density of dendritic spines in CA1 (Montrer CA1 Anticorps) neurons.

  3. neutrophil cytokine production required STIM2, but not STIM1 (Montrer STIM1 Anticorps), at least in part as a result of redox regulation of cytokine gene expression

  4. Expression of STIM2 protein rescued CaMKII (Montrer CAMK2G Anticorps) activity and protected mushroom spines from Abeta42 oligomer toxicity in vitro and in vivo.

  5. SOCE blockers or ablation of STIM1 (Montrer STIM1 Anticorps), STIM2, or Orai1 (Montrer TMEM132A Anticorps) severely impaired nucleotide-induced migration and phagocytosis in microglia.

  6. The data from this study indicate that upregulation of STIM2 and Orai2 (Montrer ORAI2 Anticorps) is involved in the phenotypic transition of pulmonary arterial smooth muscle cells from a contractile state to a proliferative state.

  7. STIM1 (Montrer STIM1 Anticorps), STIM2, and CRAC channel function play distinct but synergistic roles in CD4 (Montrer CD4 Anticorps)+ and CD8 (Montrer CD8A Anticorps)+ T cells during antiviral immunity

  8. STIM2 deficiency significantly delays onset and attenuates the clinical course of experimental allergic encephalitis.

  9. Using mice lacking STIM1 (Montrer STIM1 Anticorps) and its homologue STIM2, authors find that store-operated calcium entry in CD8 (Montrer CD8A Anticorps)(+) T cells is required to prevent the engraftment of melanoma and colon carcinoma cells and to control tumour growth.

  10. STIM1 (Montrer STIM1 Anticorps) and STIM2-mediated store-operated Ca2 (Montrer CA2 Anticorps)+ influx, leading to efficient activation of NFAT (Montrer NFATC1 Anticorps) (nuclear factor of activated T cells), is critical for the postselection maturation of agonist-selected T cells.

Stim2 profil antigène

Profil protéine

This gene is a member of the stromal interaction molecule (STIM) family and likely arose, along with related family member STIM1, from a common ancestral gene. The encoded protein functions to regulate calcium concentrations in the cytosol and endoplasmic reticulum, and is involved in the activation of plasma membrane Orai Ca(2+) entry channels. This gene initiates translation from a non-AUG (UUG) start site. A signal peptide is cleaved from the resulting protein. Multiple transcript variants result from alternative splicing.

Gene names and symbols associated with Stim2

  • stromal interaction molecule 2 (STIM2) anticorps
  • stromal interaction molecule 2 (stim2) anticorps
  • stromal interaction molecule 2 (Stim2) anticorps
  • STIM2 anticorps

Protein level used designations for Stim2

stromal interaction molecule 2

GENE ID SPECIES
100083707 Ornithorhynchus anatinus
100471703 Ailuropoda melanoleuca
100566248 Anolis carolinensis
422799 Gallus gallus
461155 Pan troglodytes
541299 Bos taurus
694980 Macaca mulatta
733739 Xenopus (Silurana) tropicalis
100540015 Meleagris gallopavo
57620 Homo sapiens
116873 Mus musculus
117087 Rattus norvegicus
Fournisseurs de qualité sélectionnés pour anti-Stim2 (Stim2) Anticorps
Avez-vous cherché autre chose?