Structural Maintenance of Chromosomes 2 Protéines (SMC2)

Members of the structural maintenance of chromosomes, or SMC, family (e.g., SMC1A\; MIM 300040) are critical for mitotic chromosome condensation in frogs and for DNA repair in mammals.[supplied by OMIM, Nov 2010].. De plus, nous expédions SMC2 Anticorps (74) et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
SMC2 10592 O95347
SMC2 14211 Q8CG48
Rat SMC2 SMC2 362519  
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Showing 3 out of 3 products:

Catalogue No. Origin Source Conjugué Images Quantité Fournisseur Livraison Prix Détails
Cellules d'insectes Humain His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 70 Days
$13,984.89
Détails
Cellules d'insectes Souris His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 70 Days
$13,984.89
Détails
Wheat germ Humain GST tag 10 μg Connectez-vous pour afficher 11 to 12 Days
$414.29
Détails

SMC2 Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Human ,
,
Mouse (Murine)

Plus protéines pour Structural Maintenance of Chromosomes 2 (SMC2) partenaires d'interaction

Human Structural Maintenance of Chromosomes 2 (SMC2) interaction partners

  1. SMC2 (or the condensin complex (Montrer SMC4 Protéines)) is a novel molecular target for the treatment of MYCN (Montrer MYCN Protéines)-amplified neuroblastoma (Montrer ARHGEF16 Protéines).

  2. analysis of functional differences of SMC2 and SMC4 hinge domain between condensins and cohesin in DNA recognition

  3. SMC2 gene is altered by both frameshift mutation and loss of expression in gastric and colorectal cancers, suggesting that SMC2 gene alterations might be involved in pathogenesis of these cancers

  4. WNT (Montrer WNT2 Protéines) signaling can directly activate SMC2 transcription as a key player in the mitotic cell division machinery.

  5. Studies indicate that tagged SMC2 subunit of the condensin complex (Montrer SMC4 Protéines) with the streptavidin-Binding Peptide (Montrer HP Protéines) optimising efficacious use of this tag for protein analysis.

  6. human SMC2 hinge domain with short coiled coils was cloned, expressed, purified and crystallized in the orthorhombic space group C222 in native and SeMet-derivatized forms

  7. mutation analysis of hCAP-C (Montrer SMC4 Protéines) & hCAP-E in leukemia-lymphoma cell lines including 8 pyothorax-associated lymphoma (PAL); 3 of 8 PAL cell lines have hCAP-C (Montrer SMC4 Protéines) or hCAP-E heterozygous mutations, indicating condensin mutations are relatively frequent in PAL

Profil protéine SMC2

Profil protéine

Members of the structural maintenance of chromosomes, or SMC, family (e.g., SMC1A\; MIM 300040) are critical for mitotic chromosome condensation in frogs and for DNA repair in mammals.

Gene names and symbols associated with SMC2

  • structural maintenance of chromosomes 2 (SMC2)
  • structural maintenance of chromosomes 2 (Smc2)
  • structural maintenance of chromosomes 2 (smc2)
  • structural maintenance of chromosomes 2 L homeolog (smc2.L)
  • 5730502P04Rik Protéine
  • AI255214 Protéine
  • AW545314 Protéine
  • CAP-E Protéine
  • CAPE Protéine
  • fb92e05 Protéine
  • Fin16 Protéine
  • SCII Protéine
  • SMC-2 Protéine
  • Smc2l1 Protéine
  • wu:fb92e05 Protéine
  • xcap-e Protéine
  • zeh1628 Protéine
  • zgc:55326 Protéine

Protein level used designations for SMC2

SMC protein 2 , SMC2 (structural maintenance of chromosomes 2, yeast)-like 1 , XCAP-E homolog , chromosome-associated protein E , structural maintenance of chromosomes (SMC) family member, chromosome-associated protein E , structural maintenance of chromosomes protein 2 , FGF-inducible protein 16 , SMC2 structural maintenance of chromosomes 2-like 1 , fibroblast growth factor inducible 16 , (XCAP-E) , chromosome assembly protein XCAP-E , chromosome scaffold protein ScII

GENE ID SPECIES
10592 Homo sapiens
14211 Mus musculus
321452 Danio rerio
397800 Xenopus laevis
396156 Gallus gallus
481637 Canis lupus familiaris
362519 Rattus norvegicus
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