Structural Maintenance of Chromosomes 4 Protéines (SMC4)

Members of the structural maintenance of chromosomes, or SMC, family (e.g., SMC1A\; MIM 300040) are critical for mitotic chromosome condensation in frogs and for DNA repair in mammals.[supplied by OMIM, Nov 2010].. De plus, nous expédions Structural Maintenance of Chromosomes 4 Anticorps (75) et Structural Maintenance of Chromosomes 4 Kits (7) et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
SMC4 10051 Q9NTJ3
SMC4 70099 Q8CG47
Rat SMC4 SMC4 295107  
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Showing 3 out of 3 products:

Catalogue No. Origin Source Conjugué Images Quantité Livraison Prix Détails
Cellules d'insectes Humain His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 70 Days
$13,741.67
Détails
Cellules d'insectes Souris His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 70 Days
$13,741.67
Détails
Wheat germ Humain GST tag 10 μg 11 to 12 Days
$414.29
Détails

SMC4 Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Human ,
,
Mouse (Murine)

Plus protéines pour Structural Maintenance of Chromosomes 4 (SMC4) partenaires d'interaction

Human Structural Maintenance of Chromosomes 4 (SMC4) interaction partners

  1. this paper shows that condensin Smc4 promotes inflammatory innate immune response by epigenetically enhancing NEMO transcription

  2. Study examined the expression of SMC4 in acute myeloid leukemia (AML) pediatric patients cells and normal cells and revealed that SMC4 was significantly higher than control. Utilizing SMC4 gene knockdown in the established MLL-AF9 AML mouse model study found that SMC4 knockdown inhibited AML progression by maintaining leukemia stem cells.

  3. analysis of functional differences of SMC2 and SMC4 hinge domain between condensins and cohesin in DNA recognition

  4. Results indicate that miR-124-5p may target the tumorigenesis gene, SMC4, which suggests that expression levels of miR-124-5p in plasma and FFPE samples.

  5. Knockdown of SMC-4 expression significantly suppressed the proliferation.

  6. SMC4 expression was significantly associated with tumor size, de-differentiation, advanced stages and vascular invasion of the primary liver cancers.

  7. mutation analysis of hCAP-C & hCAP-E in leukemia-lymphoma cell lines including 8 pyothorax-associated lymphoma (PAL); 3 of 8 PAL cell lines have hCAP-C or hCAP-E heterozygous mutations, indicating condensin mutations are relatively frequent in PAL

Mouse (Murine) Structural Maintenance of Chromosomes 4 (SMC4) interaction partners

  1. Study examined the expression of SMC4 in acute myeloid leukemia (AML) pediatric patients cells and normal cells and revealed that SMC4 was significantly higher than control. Utilizing SMC4 gene knockdown in the established MLL-AF9 AML mouse model study found that SMC4 knockdown inhibited AML progression by maintaining leukemia stem cells.

Arabidopsis thaliana Structural Maintenance of Chromosomes 4 (SMC4) interaction partners

  1. silencing of transposons in the pericentromeric heterochromatin of Arabidopsis thaliana requires SMC4.

  2. results reveal a critical role for AtCAP-C during cell division

Profil protéine Structural Maintenance of Chromosomes 4 (SMC4)

Profil protéine

Members of the structural maintenance of chromosomes, or SMC, family (e.g., SMC1A\; MIM 300040) are critical for mitotic chromosome condensation in frogs and for DNA repair in mammals.

Gene names and symbols associated with SMC4

  • Structural maintenance of chromosomes protein 4 (smc-4)
  • structural maintenance of chromosomes 4 (SMC4)
  • structural maintenance of chromosomes 4 (Smc4)
  • structural maintenance of chromosomes 4 (smc4)
  • structural maintenance of chromosomes 4 L homeolog (smc4.L)
  • structural maintenance of chromosome 3 (SMC3)
  • 2500002A22Rik Protéine
  • ARABIDOPSIS THALIANA CHROMOSOME ASSOCIATED PROTEIN-C Protéine
  • ARABIDOPSIS THALIANA STRUCTURAL MAINTENANCE OF CHROMOSOME 4 Protéine
  • ATCAP-C Protéine
  • ATSMC3 Protéine
  • ATSMC4 Protéine
  • C79747 Protéine
  • CAP-C Protéine
  • CAPC Protéine
  • cb788 Protéine
  • chunp6901 Protéine
  • fb99b10 Protéine
  • hCAP-C Protéine
  • K15N18.7 Protéine
  • K15N18_7 Protéine
  • SMC-4 Protéine
  • smc4l1 Protéine
  • structural maintenance of chromosome 3 Protéine
  • STRUCTURAL MAINTENANCE OF CHROMOSOMES 3 Protéine
  • wu:fb99b10 Protéine
  • xcap-c Protéine

Protein level used designations for SMC4

SMC protein 4 , SMC4 structural maintenance of chromosomes 4-like 1 , XCAP-C homolog , chromosome-associated polypeptide C , structural maintenance of chromosomes protein 4 , MC4 structural maintenance of chromosomes 4-like 1 , (XCAP-C) , chromosome assembly protein XCAP-C , chromosome-associated protein C , condensin complex subunit

GENE ID SPECIES
175603 Caenorhabditis elegans
10051 Homo sapiens
478679 Canis lupus familiaris
353350 Bos taurus
70099 Mus musculus
295107 Rattus norvegicus
192332 Danio rerio
397799 Xenopus laevis
395189 Gallus gallus
100152361 Sus scrofa
834917 Arabidopsis thaliana
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