anti-Suppressor of Variegation 3-9 Homolog 1 (Drosophila) (SUV39H1) Anticorps

SUV39H1 is a member of the suppressor of variegation 3-9 homolog family and encodes a protein with a chromodomain and a C-terminal SET domain. De plus, nous expédions Suppressor of Variegation 3-9 Homolog 1 (Drosophila) Protéines (8) et et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
SUV39H1 6839 O43463
SUV39H1 20937 O54864
SUV39H1 302553  
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Top anti-Suppressor of Variegation 3-9 Homolog 1 (Drosophila) Anticorps sur anticorps-enligne.fr

Showing 10 out of 107 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB WB Suggested Anti-SUV39H1 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  721_B cell lysate SUV39H1 is supported by BioGPS gene expression data to be expressed in 721_B Rabbit Anti-SUV39H1 antibody   Paraffin Embedded Tissue: Human Lung cell Cellular Data: alveolar cell of renal tubule Antibody Concentration: 4.0-8.0 ug/ml Magnification: 400X 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Humain Lapin Inconjugué WB SUV39H1 (ABIN387991) western blot analysis in MDA-MB435 cell line lysates (35 µg/lane). This demonstrates the SUV39H1 antibody detected the SUV39H1 protein (arrow). 400 μL Connectez-vous pour afficher 10 to 11 Days
$385.00
Détails
Humain Lapin Inconjugué WB SUV39H1 Antibody (N-term) (ABIN657943) western blot analysis in 293 cell line lysates (35 µg/lane). This demonstrates the SUV39H1 antibody detected the SUV39H1 protein (arrow). Anti-SUV39H1 Antibody (N-term) at 1:1000 dilution + MCF-7 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 48 kDa Blocking/Dilution buffer: 5% NFDM/TBST. Dilution: 1:1000 400 μL Connectez-vous pour afficher 10 to 11 Days
$385.00
Détails
Boeuf (Vache) Lapin Inconjugué IHC, WB WB Suggested Anti-SUV39H1 Antibody Titration:  1.25ug/ml  ELISA Titer:  1:312500  Positive Control:  HepG2 cell lysate SUV39H1 is supported by BioGPS gene expression data to be expressed in HepG2 Human Intestine 100 μL Connectez-vous pour afficher 2 to 3 Days
$229.00
Détails
Humain Souris Inconjugué WB Western analysis of extracts from 293 cells using SUV39H1 antibody. 400 μL Connectez-vous pour afficher 10 to 11 Days
$385.00
Détails
Humain Lapin Inconjugué IHC, IHC (p), IP, WB Immunohistochemistry: KMT1A/SUV39H1 Antibody [NBP1-21367] - IHC analysis of KMT1A/SUV39H1 in human breast cancer using DAB with hematoxylin counterstain. Western Blot: KMT1A/SUV39H1 Antibody [NBP1-21367] - Up: SUV39H1 expression in C6 astrocytic cell line and human glioma cell lines GOS-3, T98G, U87MG and 1321N1. Down: Actin levels. Image from confirmed customer review. 0.1 mL Connectez-vous pour afficher 7 to 9 Days
$559.35
Détails
Humain Lapin Inconjugué EIA, IHC (p), WB 0.4 mL Connectez-vous pour afficher 6 to 8 Days
$484.00
Détails
Humain Lapin Inconjugué ICC, IF, IHC, IHC (p), IP, WB Western Blot: KMT1A/SUV39H1 Antibody [NBP2-17086] - Sample (30 ug of whole cell lysate) A: H1299 B: Hep G2 C: Raji 10% SDS PAGE gel, diluted at 1:1000. Immunohistochemistry-Paraffin: KMT1A/SUV39H1 Antibody [NBP2-17086] - Immunohistochemical analysis of paraffin-embedded Cal27 Xenograft, using antibody at 1:100 dilution. 0.1 mL Connectez-vous pour afficher 8 to 11 Days
$516.98
Détails
Boeuf (Vache) Lapin Inconjugué IHC, IHC (p), WB 100 μg Connectez-vous pour afficher 11 to 14 Days
$493.17
Détails
Humain Souris Inconjugué EIA, WB 0.4 mL Connectez-vous pour afficher 6 to 8 Days
$484.00
Détails

anti-Suppressor of Variegation 3-9 Homolog 1 (Drosophila) Anticorps mieux référencés

  1. Human Monoclonal SUV39H1 Primary Antibody pour ELISA, WB - ABIN533015 : Østrup, Hyttel, Klærke, Collas: Remodeling of ribosomal genes in somatic cells by Xenopus egg extract. dans Biochemical and biophysical research communications 2011 (PubMed)
    Show all 4 Pubmed References

  2. Human Polyclonal SUV39H1 Primary Antibody pour IHC (fro), ELISA - ABIN543324 : Schotta, Ebert, Krauss, Fischer, Hoffmann, Rea, Jenuwein, Dorn, Reuter: Central role of Drosophila SU(VAR)3-9 in histone H3-K9 methylation and heterochromatic gene silencing. dans The EMBO journal 2002 (PubMed)
    Show all 3 Pubmed References

  3. Human Monoclonal SUV39H1 Primary Antibody pour ChIP, IP - ABIN2668694 : Terada: Aurora-B/AIM-1 regulates the dynamic behavior of HP1alpha at the G2-M transition. dans Molecular biology of the cell 2006 (PubMed)
    Show all 3 Pubmed References

  4. Human Polyclonal SUV39H1 Primary Antibody pour IHC, IHC (p) - ABIN439327 : Ayrapetov, Xu, Sun, Zhu, Parmar, DAndrea, Price: Activation of Hif1α by the prolylhydroxylase inhibitor dimethyoxalyglycine decreases radiosensitivity. dans PLoS ONE 2011 (PubMed)
    Show all 2 Pubmed References

  5. Human Polyclonal SUV39H1 Primary Antibody pour WB - ABIN387991 : Fujita, Watanabe, Ichimura, Tsuruzoe, Shinkai, Tachibana, Chiba, Nakao: Methyl-CpG binding domain 1 (MBD1) interacts with the Suv39h1-HP1 heterochromatic complex for DNA methylation-based transcriptional repression. dans The Journal of biological chemistry 2003 (PubMed)
    Show all 7 Pubmed References

  6. Human Polyclonal SUV39H1 Primary Antibody pour WB - ABIN6688320 : Zhao, Lei, Zhang, Zheng, Wang, Zhao, Li, Ye, Li, Wei, Wu: Global histone modification profiling reveals the epigenomic dynamics during malignant transformation in a four-stage breast cancer model. dans Clinical epigenetics 2016 (PubMed)

Plus d’anticorps contre Suppressor of Variegation 3-9 Homolog 1 (Drosophila) partenaires d’interaction

Human Suppressor of Variegation 3-9 Homolog 1 (Drosophila) (SUV39H1) interaction partners

  1. unveil E4BP4 as a critical transcriptional modulator repressing RASSF8 expression through histone methyltransferases, G9a and SUV39H1.

  2. E-cadherin silencing relies on the formation of a complex between the paRNA and microRNA-guided Argonaute 1 that, together, recruit SUV39H1 and induce repressive chromatin modifications in the gene promoter

  3. SUV39H1 dysregulation may be involved in diabetic nephropathy progression, affecting inflammation and apoptosis.

  4. KMT1A positively regulated the self-renewal and tumorigenicity of human Bladder cancer stem cells via KMT1A-GATA3-STAT3 circuit, in which KMT1A could be a promising target for bladder cancer therapy.

  5. Here, the authors demonstrate that chromatin-associated RNA contributes to the stable association of SUV39H1 with constitutive heterochromatin in human cells.

  6. Here the authors show that Suv39h1 chromodomain binds nucleic acids, and this binding is important for its function in heterochromatin assembly.

  7. SirT6 promotes cysteine ubiquitination in the PRE-SET domain of Suv39h1.

  8. Our data show that the differential expression of SUV39H1 and SUV39H2 is associated with genomic instability and that the modulation of these HMTases can be an attractive approach to prevent CLL evolution

  9. Overexpression of miR-125b and inhibition of its target, SUV39H1, in aging individuals reduces hematopoietic stem cells capacity of B cells generation.

  10. KAT7-containing acetyltransferases associating with the Mis18 complex provides competence for histone turnover/exchange activity on alphoid DNA and prevents Suv39h1-mediated heterochromatin invasion into centromeres.

  11. Suv39h1 deficiency abrogates stress-dependent upregulation of HP1alpha and gamma, and enhances HP1beta levels.

  12. Lysine methyltransferases (KMTs) that mediate methylation marks on histone and non-histone proteins are now recognized as important regulators of gene expression in cycling and non-cycling cells. Among these, the SUV39 sub-family of KMTs.

  13. we describe the synthesis of multidomain 'designer chromatin' templates and their application to dissecting the regulation of human Suv39h1

  14. These results suggest a model in which SUV39H1 downregulation promotes the establishment of cellular senescence.

  15. CRL4B promotes tumorigenesis by coordinating with SUV39H1/HP1/DNMT3A in DNA methylation-based epigenetic silencing

  16. PHF2 is likely to repress rDNA transcription by competing with PHF8 for binding of ribosomal DNA promoter and by recruiting H3K9me2/3 methyltransferase SUV39H1.

  17. High SUV39H1 expression is associated with hepatocellular carcinoma.

  18. Suv39H1 induced apoptosis and inhibited cell proliferation in the gastric cancer MGC803 cell line, while decreasing BCL-2, pro-caspase-9, pro-caspase-3 and C-myc. Suv39H1 may be a potential gene target for anti-gastric carcinoma therapy.

  19. SUV39H1 expression was upregulated in glioma cell lines and in glioma tissues compared to normal brain, being positively correlated with grade and histological malignancy.

  20. Short-chain fatty acids from periodontal pathogens suppress EZH2, and SUV39H1 to promote Kaposi's sarcoma-associated herpesvirus replication.

Mouse (Murine) Suppressor of Variegation 3-9 Homolog 1 (Drosophila) (SUV39H1) interaction partners

  1. SUV39H augments intracellular reactive oxygen species levels in a SIRT1-dependent manner.

  2. this novel defense mechanism against mycobacteria represents a surrogate function of the epigenetic modulator, SUV39H1, and operates by interfering with their cell-cell adhesion ability.

  3. the Suv39h1 paralog, is identified as a unique enhancer of HP1alpha sumoylation

  4. The authors show here that the mouse Suv39h2 enzyme differs from Suv39h1 by containing an N-terminal basic domain that facilitates retention at mitotic chromatin and provides an additional affinity for major satellite repeat RNA.

  5. Suv39h1 plays a critical role in marking chromatin to silence stem/memory genes during CD8+ T effector terminal differentiation

  6. Histone methyltransferase Suv39h1 attenuates high glucose-induced fibronectin and p21(WAF1) in mesangial cells

  7. Overexpression of miR-125b and inhibition of its target, SUV39H1, in aging individuals reduces hematopoietic stem cells capacity of B cells generation.

  8. Activation of p38alpha displaces KMT1A from MyoD to initiate myogenic gene expression upon induction of myoblasts differentiation.

  9. Oct4P4 lncRNA forms a complex with the SUV39H1 HMTase to direct the imposition of H3K9me3 and HP1alpha to the promoter of the ancestral Oct4 gene, located on chromosome 17, leading to gene silencing and reduced mESC self-renewal.

  10. Provide genetic evidence that Suv39h1 controls telomere homeostasis and mediates resistance to oncogenic stress in vivo, conferring resistance to skin carcinogenesis.

  11. Repeat-associated, Suv39h-dependent H3K9me3 displays a dynamic distribution that differs in the epigenome of pluripotent versus more committed cells.

  12. These findings indicate that Suv39h1 enhances AP-2alpha-mediated transcriptional repression of C/EBPalpha in an epigenetic manner and further inhibits adipocyte differentiation.

  13. A-type lamins interact with SUV39H1, and prelamin A/progerin exhibits enhanced binding capacity to SUV39H1, protecting it from proteasomal degradation and, consequently, increasing H3K9me3 levels.

  14. Data indicate that loss of suv39h1 prevents Myc-induced chromosomal instability.

  15. Smads recruit H3K9 methyltransferases Suv39h1 to the IL-2 promoter, thereby inducing suppressive histone methylation and inhibiting T cell receptor-mediated IL-2 transcription.

  16. SirT1 preserves heterochromatin structure: it modulates Suv39h1 protein levels in stress conditions by preventing MDM2-mediated polyubiquitination at K87.

  17. novel role for microRNA in the epigenetic regulation of inflammatory genes in vascular smooth muscle cells of diabetic mice through downregulation of SUV39h1.

  18. Ring1B and Suv39h1 have mutually exclusive roles in regulating distinct chromatin states at key developmental genes, and play a part in how lineage specification can be reinforced during early development

  19. SUV39h1 associated with HP1 beta in fibrillarin-positive nucleolar regions.

  20. SUV39h and A-type lamins likely play a key role in telomere maintenance and telomere nuclear architecture.

Zebrafish Suppressor of Variegation 3-9 Homolog 1 (Drosophila) (SUV39H1) interaction partners

  1. The identification of a histone H3 lysine 9 histone methyltransferase, SUV39H1, as a suppressor of embryonal rhabdomyosarcoma formation in zebrafish, is described.

  2. These results suggest that Dnmt1 activity helps direct histone methylation by Suv39h1 and that, together, Dnmt1 and Suv39h1 help guide the terminal differentiation of particular tissues.

Suppressor of Variegation 3-9 Homolog 1 (Drosophila) (SUV39H1) profil antigène

Profil protéine

This gene is a member of the suppressor of variegation 3-9 homolog family and encodes a protein with a chromodomain and a C-terminal SET domain. This nuclear protein moves to the centromeres during mitosis and functions as a histone methyltransferase, methylating Lys-9 of histone H3. Overall, it plays a vital role in heterochromatin organization, chromosome segregation, and mitotic progression.

Gene names and symbols associated with SUV39H1

  • suppressor of variegation 3-9 homolog 1 (SUV39H1) anticorps
  • suppressor of variegation 3-9 homolog 1 (Drosophila) (Suv39h1) anticorps
  • suppressor of variegation 3-9 homolog 1 L homeolog (suv39h1.L) anticorps
  • suppressor of variegation 3-9 homolog 1a (suv39h1a) anticorps
  • suppressor of variegation 3-9 homolog 1 (Suv39h1) anticorps
  • suppressor of variegation 3-9 homolog 1b (suv39h1b) anticorps
  • AI852103 anticorps
  • AL022883 anticorps
  • DXHXS7466e anticorps
  • fe02c04 anticorps
  • fe47h06 anticorps
  • H3-K9-HMTase 1 anticorps
  • kmt1a anticorps
  • MG44 anticorps
  • mIS6 anticorps
  • RGD1565028 anticorps
  • suv39h anticorps
  • suv39h1 anticorps
  • wu:fb18a10 anticorps
  • wu:fe02c04 anticorps
  • wu:fe47h06 anticorps
  • zgc:101027 anticorps
  • zgc:136593 anticorps

Protein level used designations for SUV39H1

Su(var)3-9 homolog 1 , histone H3-K9 methyltransferase 1 , histone-lysine N-methyltransferase SUV39H1 , histone-lysine N-methyltransferase, H3 lysine-9 specific 1 , lysine N-methyltransferase 1A , position-effect variegation 3-9 homolog , H3-K9-HMTase 1 , Suv39h histone methyltransferase , su(var)3-9 homolog 1 , histone-lysine N-methyltransferase SUV39H1-A , su(var)3-9 homolog 1-A , suppressor of variegation 3-9 homolog 1 , suppressor of variegation 3-9 homolog 1-A , suppressor of variegation 3-9-like 1a , LOW QUALITY PROTEIN: histone-lysine N-methyltransferase SUV39H1 , suppressor of variegation 3-9-like 1b homolog 1

GENE ID SPECIES
6839 Homo sapiens
20937 Mus musculus
302553 Rattus norvegicus
431943 Xenopus laevis
445198 Danio rerio
523047 Bos taurus
100172621 Pongo abelii
491868 Canis lupus familiaris
100731248 Cavia porcellus
326906 Danio rerio
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