anti-Surfactant Protein D (SFTPD) Anticorps

Contributes to the lung's defense against inhaled microorganisms. De plus, nous expédions Surfactant Protein D Kits (85) et Surfactant Protein D Protéines (28) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
SFTPD 6441 P35247
SFTPD 25350 P35248
SFTPD 20390 P50404
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Top anti-Surfactant Protein D Anticorps sur

Showing 10 out of 180 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Chien Lapin Inconjugué WB WB Suggested Anti-SFTPD Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:1562500  Positive Control:  Human Thymus 100 μL Connectez-vous pour afficher 2 to 3 Days
Humain Lapin Inconjugué IHC (p), ELISA, WB 100 μg Connectez-vous pour afficher 4 to 6 Days
Humain Lapin Inconjugué IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human lung carcinoma labeled with Anti-SP-D PSPD Polyclonal Antibody, unconjugated (ABIN731678) at 1:200, followed by incubation with conjugated secondary antibody and DAB staining. Formalin-fixed and paraffin embedded rat lung labeled with Anti-SP-D PSPD Polyclonal Antibody, unconjugated (ABIN731678) at 1:200, followed by incubation with conjugated secondary antibody and DAB staining. 100 μL Connectez-vous pour afficher 3 to 7 Days
Porc Souris Inconjugué ICC, IHC (fro), IF, IHC (p), IHC, WB Immunohistochemistry-Paraffin: SP-D Antibody (1.7) [NBP1-41050] - Staining of frozen pig lung with Mouse anti pig Surfactant Protein D 0.125 mg Connectez-vous pour afficher 7 to 9 Days
Souris Lapin Inconjugué ICC, IHC, WB Western Blot; Sample: Mouse Lung lysate; Primary Ab: 2µg/ml Rabbit Anti-Mouse SPD Antibody Second Ab: 0.2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: SAA544Rb19) 100 μg Connectez-vous pour afficher 13 to 16 Days
Humain Lapin Inconjugué WB SFTPD Antibody (C-term) (ABIN657919) western blot analysis in MDA-MB435 cell line lysates (35 µg/lane). This demonstrates the SFTPD antibody detected the SFTPD protein (arrow). 400 μL Connectez-vous pour afficher 10 to 11 Days
Humain Lapin Inconjugué IHC, IHC (p), WB Immunohistochemistry-Paraffin: SP-D Antibody [NBP2-33424] - testis Immunohistochemistry-Paraffin: SP-D Antibody [NBP2-33424] - Immunohistochemical staining of human lung shows strong cytoplasmic positivity in subset of pneumocytes. 0.1 mL Connectez-vous pour afficher 10 to 13 Days
Chien Lapin Inconjugué WB 50 μg Connectez-vous pour afficher 11 to 14 Days
Humain Souris Biotin EIA, IHC (fro), WB   0.2 mg Connectez-vous pour afficher 6 to 8 Days
Humain Souris Inconjugué ELISA, IHC, IHC (p), WB Human Thyroid: Formalin-Fixed, Paraffin-Embedded (FFPE) Human, Lung: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Connectez-vous pour afficher 11 to 14 Days

anti-Surfactant Protein D Anticorps mieux référencés

  1. Pig (Porcine) Monoclonal SFTPD Primary Antibody pour ICC, IHC (fro) - ABIN445379 : Soerensen, Holmskov, Aalbaek, Boye, Heegaard, Nielsen: Pulmonary infections in swine induce altered porcine surfactant protein D expression and localization to dendritic cells in bronchial-associated lymphoid tissue. dans Immunology 2005 (PubMed)
    Show all 3 Pubmed References

  2. Rat (Rattus) Monoclonal SFTPD Primary Antibody pour IA, IHC (p) - ABIN2192111 : Kasper, Albrecht, Grossmann, Grosser, Schuh, Müller: Monoclonal antibodies to surfactant protein D: evaluation of immunoreactivity in normal rat lung and in a radiation-induced fibrosis model. dans Experimental lung research 1995 (PubMed)
    Show all 2 Pubmed References

  3. Human Polyclonal SFTPD Primary Antibody pour IF (p), IHC (p) - ABIN731678 : Sung, Liang, Lee, Yen, Hsiao, Wang, Jiang-Shieh, Tsai, Chen: The protective effect of eupafolin against TNF-?-induced lung inflammation via the reduction of intercellular cell adhesion molecule-1 expression. dans Journal of ethnopharmacology 2015 (PubMed)
    Show all 2 Pubmed References

  4. Pig (Porcine) Monoclonal SFTPD Primary Antibody pour IHC (fro), IF - ABIN2476640 : : The influence of varicocele on parameters of fertility in a large group of men presenting to infertility clinics. World Health Organization. dans Fertility and sterility 1992 (PubMed)
    Show all 2 Pubmed References

  5. Human Monoclonal SFTPD Primary Antibody pour EIA, IHC (fro) - ABIN111974 : Bräuer, Kindler, Jäger, Sel, Nölle, Pleyer, Ochs, Paulsen: Detection of surfactant proteins A and D in human tear fluid and the human lacrimal system. dans Investigative ophthalmology & visual science 2007 (PubMed)
    Show all 2 Pubmed References

  6. Human Monoclonal SFTPD Primary Antibody pour IHC, WB - ABIN395257 : Uhliarova, Kopincova, Adamkov, Svec, Calkovska: Surfactant proteins A and D are related to severity of the disease, pathogenic bacteria and comorbidity in patients with chronic rhinosinusitis with and without nasal polyps. dans Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery 2017 (PubMed)

Plus d’anticorps contre Surfactant Protein D partenaires d’interaction

Human Surfactant Protein D (SFTPD) interaction partners

  1. these findings indicate that the membrane-type surfactant protein D serve as an effective therapeutic strategy for inhibiting macrophage-mediated xenograft rejection in xenotransplantation

  2. Assays that can separate SP-D proteolytic breakdown products or modified forms from naturally occurring SP-D trimers may result in optimal disease markers for pulmonary inflammatory diseases

  3. TGF beta markedly decreased expression of SP-A, SP-B, SP-C, fatty acid synthase, and the phospholipid transporter ABCA3. However, TGF beta increased protein levels of SP-D with little change in mRNA levels.

  4. the SPA and SPD levels in EBC were correlated with lung function, which contributed to COPD diagnosis.

  5. Studied predictive value of surfactant protein D (SP-D) in lung cancer patients with interstitial lung disease induced by anticancer agents (ILD-AA). Results suggest that SP-D level change was a risk factor for mortality in patients with ILD-AA, and that SP-D might be a predictive prognostic biomarker of ILD-AA.

  6. SP-D also delays FasL-induced death of primary human T cells. SP-D delaying the progression of the extrinsic pathway of apoptosis could have important implications in regulating immune cell homeostasis at mucosal surfaces

  7. findings suggest that these pulmonary markers could be useful to assess CAP severity and, especially YKL-40 and CCL18 by helping predict CAP caused by atypical pathogens

  8. Trimeric SP-D wildtype recognized larger LPS inner core oligosaccharides with slightly enhanced affinity than smaller compounds suggesting the involvement of stabilizing secondary interactions.

  9. rs2819096 in the surfactant protein D (SFTPD) gene was associated with a higher risk of COPD GOLD III + IV.

  10. SP-D increases the formation of nuclear and membrane blebs. Inhibition of caspase-8 confirms the effect of SP-D is unique to the caspase-8 pathway.

  11. Findings indicate serum pulmonary surfactant protein D (SP-D, SFTPD) level as a potential marker to estimate the efficacy of epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitor (TKIs).

  12. Patients with SP-D 11Thr/Thr genotype were more susceptible to acute kidney injury (AKI). Compared with healthy controls, serum SP-D levels at day 1, 3 and 7 were significantly elevated in AKI patients.

  13. This review intends to provide a current overview of the genetics, structure and extra-pulmonary functions of the surfactant collectin proteins.

  14. Meta-analysis found that serum SP-A/D detection might be useful for differential diagnosis and prediction of survival in patients with idiopathic pulmonary fibrosis.

  15. The findings suggest that SP-D inhibits LPS-stimulated production of interleukin-12p40 via the SIRPalpha/ROCK/ERK signaling pathway.

  16. Efficient lipopolysaccharide recognition by SP-D requires multiple binding interactions utilizing the three major ligand-binding determinants in the SP-D binding pocket, with Ca-dependent binding of inner-core heptose accompanied by interaction of anhydro-Kdo (4,7-anhydro-3-deoxy-d-manno-oct-2-ulosonic acid) with Arg343 and Asp325.

  17. SP-D levels in bronchoalveolar lavage samples were significantly lower in severe asthma compared with healthy controls and mild asthma. Serum SP-D was significantly increased in severe asthma compared with healthy controls and mild asthma.

  18. SP-A (+186A/G) and SP-B (1580C/T) polymorphisms are strongly associated with the risk of respiratory distress syndrome (RDS) in preterm infants. Notably, reduced serum SP-A levels were correlated with a high risk of RDS and may serve as novel biomarkers for RDS detection and monitoring.

  19. Obstructive sleep apnea-hypopnea syndrome pathogenesis was associated with changes in NF-kappaB, HIF-1alpha, and SPD protein expression level

  20. Surfactant protein D levels differed among idiopathic pulmonary fibrosis, pulmonary sarcoidosis and chronic pulmonary obstructive disease.

Cow (Bovine) Surfactant Protein D (SFTPD) interaction partners

  1. Elevation of SP-D is found in bronchoalveolar lavage fluid from inoculated lobes of calves infected with bovine adenovirus type 3.

  2. The bSP-D gene has 9 exons spanning about 10.5 kb on chromosome 28 at position q1.8. The 5'-upstream sequence has cis-regulatory elements. It has 2 polymorphisms in the carbohydrate recognition domain (242 Glu/Val & 268 Ala/Gly).

Pig (Porcine) Surfactant Protein D (SFTPD) interaction partners

  1. The authors demonstrated that the number and position of glycosylation sites determine viral susceptibility to the neutralizing activity of porcine SP-D.

  2. Data show that interactions of surfactant protein D (pSP-D) with influenza A virus mediated by the N-linked carbohydrate moiety in pSP-D depend on the terminal sialic acids present on this moiety.

  3. The presence of SP-D in endothelial cells which is NO-, PI(3)K/Akt- and Erk-dependent is demonstrated. It suggests a protective role of SP-D in these cells.

  4. The importance of SP-D in innate immunity is underlined by its expression at the potential ports of entry of pathogens: lung, tongue, intestinal tract, thymus, skin, gall bladder, lacrimal gland, esophagus, stomach, kidney, liver, prostate and spleen.

Mouse (Murine) Surfactant Protein D (SFTPD) interaction partners

  1. Loss of Sftpd do not result in retinal degeneration.

  2. Colitis caused a notable increase in Sftpd gene expression in the gallbladder, but not in the lung, via the activity of glucocorticoids produced in the liver.

  3. SP-D deficiency reduces atherosclerosis in ApoE-knockout mice by decreasing the accumulation and proliferation of macrophages and by reducing IL-6 levels systemically.

  4. The data provide evidence SP-A and SP-D attenuate S. aureus pneumonia severity resulting in decreased intestinal mucosal injury, apoptosis, and inflammation.

  5. In triple KO mice, the HO-induced lung injury was associated with decreased surfactant protein (SP) A and SPC but not SPB and SPD expression.

  6. Our study provides comprehensive information regarding spatial and temporal expression of collectins (SP-A, SP-D and MBL-A) and their cellular sources in murine testis. Positive regulation by testosterone and alteration in their level upon LPS challenge are clues relevant to suggest their involvement in testicular immune privilege.

  7. Our data may promote further studies on the morphological development of the aging lung and the role of SP-D in this process.

  8. The experimentally induced alterations were more severe in the SP-D(-/-) than in the WT mice, particularly with respect to the surfactant-storing lamellar bodies which were sometimes extremely enlarged in SP-D(-/-) mice.

  9. these results demonstrate SP-D plays protective roles by inhibiting apoptosis and modulating NF-kappaB-mediated inflammation in CLP-induced acute pancreatic injury .

  10. SP-A/D double knock-out mice showed increased susceptibility to urinary tract infection

  11. Human and murine data together indicate that SP-A, SP-D and MBL are synthesized in early gestational tissues, and may contribute to regulation of immune response at the feto-maternal interface during pregnancy.

  12. The presence of SP-A and SP-D in the murine decidua is likely to play a protective role against intrauterine infection during pregnancy.

  13. our results demonstrate that SFTPD deficiency affects female fertility, highlighting roles for SFTPD in ovarian and uterine physiology

  14. the collectin Surfactant Protein D is an essential component of host innate immunity to helminths

  15. SP-D protects the ocular surface from S. aureus infection.

  16. Estrogen positively regulates expression of SP-D in the mouse uterus. Progesterone, along with estrogen synergizes SP-D expression, however, when administered alone results in negative regulation.

  17. NOS2 mediates remodeling of septal walls, resulting in deposition of interstitial tissue in Sftpd(-/-).

  18. Suggest a protective role for SP-D in the pathogenesis of sub-epithelial fibrosis in a mouse model of allergic inflammation through regulation of eosinophil-derived TGF-beta1.

  19. Data indicate that although iNOS is involved in radiation-induced injury and altered SP-D structure, in the absence of SP-D, it functions to promote proinflammatory signaling.

  20. SP-A and SP-D attenuate kidney injury by modulating inflammation and apoptosis in sepsis-induced AKI.

Horse (Equine) Surfactant Protein D (SFTPD) interaction partners

  1. Surfactant protein D and haptoglobin serum concentrations could be a diagnostic aid for equine inflammatory airway disease.

  2. The levels of surfactant protein D and serum amyloid A protein in normal horses and those with bacterial pneumonia are reported.

Surfactant Protein D (SFTPD) profil antigène

Profil protéine

Contributes to the lung's defense against inhaled microorganisms. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties.

Gene names and symbols associated with SFTPD

  • surfactant protein D (SFTPD) anticorps
  • surfactant protein D (Sftpd) anticorps
  • surfactant protein D (SP-D) anticorps
  • surfactant associated protein D (Sftpd) anticorps
  • AI573415 anticorps
  • COLEC7 anticorps
  • PSP-D anticorps
  • Sftp4 anticorps
  • SP-D anticorps
  • SPD anticorps

Protein level used designations for SFTPD

collectin 7 , collectin-7 , lung surfactant protein D , pulmonary surfactant apoprotein , pulmonary surfactant-associated protein D , surfactant, pulmonary-associated protein D , surfactant-associated protein, pulmonary 4 , CP4 , PSP-D , pulmonary surfactant protein D , surfactant associated protein D , surfactant protein D , carbohydrate recognition domain , SP-D , LOW QUALITY PROTEIN: pulmonary surfactant-associated protein D

6441 Homo sapiens
25350 Rattus norvegicus
282072 Bos taurus
397198 Sus scrofa
443191 Ovis aries
489066 Canis lupus familiaris
678657 Macaca mulatta
20390 Mus musculus
100728956 Cavia porcellus
102119038 Macaca fascicularis
100357777 Oryctolagus cuniculus
100066341 Equus caballus
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