anti-Symplekin (SYMPK) Anticorps

SYMPK encodes a nuclear protein that functions in the regulation of polyadenylation and promotes gene expression. De plus, nous expédions Symplekin Protéines (8) et Symplekin Kits (4) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
SYMPK 8189 Q92797
SYMPK 68188  
SYMPK 292683  
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Top anti-Symplekin Anticorps sur anticorps-enligne.fr

Showing 10 out of 47 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Humain Lapin Inconjugué WB WB Suggested Anti-SYMPK Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  HepG2 cell lysate SYMPK is supported by BioGPS gene expression data to be expressed in HepG2 WB Suggested Anti-SYMPK <br /> Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500 <br /> Positive Control: HepG2 cell lysate <br /> SYMPK is supported by BioGPS gene expression data to be expressed in HepG2 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Boeuf (Vache) Lapin Inconjugué IHC, WB WB Suggested Anti-SYMPK Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:1562500  Positive Control:  Human Liver Sample Type :  Human HT29 cells  Primary Antibody Dilution :  1:50  Secondary Antibody :  Donkey anti Rabbit-Alexa Fluor 488  Secondary Antibody Dilution :  1:500  Color/Signal Descriptions :  Green: Symplekin Blue: DAPI  Gene Name :  SYMPK  Submitted by :  Louise Lagerqvist (PhD), Oncology Department, Institute of Functional Genomics, Montpellier, France. 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Humain Lapin Inconjugué IHC (fro), IHC (p), IP, IHC, WB Immunohistochemistry-Paraffin: Symplekin Antibody [ABIN2616692] - FFPE section of human seminoma. Affinity purified rabbit anti-Symplekin used at a dilution of 1:250. Detection: DAB staining using Immunohistochemistry Accessory Kit 0.1 mL Connectez-vous pour afficher 7 to 9 Days
$556.31
Détails
Humain Souris Inconjugué ELISA, IF, IHC, WB Immunofluorescence of monoclonal antibody to SYMPK on HeLa cell (antibody concentration 10 µg/mL). SYMPK monoclonal antibody (M03), clone 4C2 Western Blot analysis of SYMPK expression in COLO 320 HSR. 100 μg Connectez-vous pour afficher 8 to 11 Days
$461.00
Détails
Humain Lapin Inconjugué IP, WB Western Blot: Symplekin Antibody  - Detection of Human and Mouse Symplekin by Western Blot. Samples: Whole cell lysate from HeLa, (5, 15 and 50 ug), and 293T (50ug) cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-Symplekin antibody  used for WB at 0.02 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes. 100 μL Connectez-vous pour afficher 7 to 9 Days
$556.31
Détails
Humain Lapin Inconjugué WB 50 μg Connectez-vous pour afficher 7 to 9 Days
$551.83
Détails
Humain Lapin Inconjugué WB 50 μg Connectez-vous pour afficher 7 to 9 Days
$551.83
Détails
Humain Lapin Inconjugué IHC, IP, WB 100 μL Connectez-vous pour afficher 7 to 9 Days
$556.31
Détails
Humain Souris Inconjugué ELISA, IF, IHC, IHC (p), WB Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE) Anti-SYMPK / Symplekin antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. 50 μg Connectez-vous pour afficher 11 to 14 Days
$727.83
Détails
Humain Lapin Inconjugué WB Western blot analysis of extract of various cells, using SYMPK antibody. 100 μL Connectez-vous pour afficher 16 Days
$334.77
Détails

Plus d’anticorps contre Symplekin partenaires d’interaction

Human Symplekin (SYMPK) interaction partners

  1. Data indicate rs56848936 in the gene symplekin protein (SYMPK) at 19q13.3, associated with colon cancer risk.

  2. CPSF2 (Montrer CPSF2 Anticorps) and SYMPK, are RBFOX2 (Montrer RBM9 Anticorps) cofactors for both inclusion and exclusion of internal exons.

  3. Symplekin interacts and co-localizes with both MOZ (Montrer MYST3 Anticorps) and MLL (Montrer MLL Anticorps) in immature hematopoietic cells. Its inhibition leads to a decrease of the HOXA9 (Montrer HOXA9 Anticorps) protein level but not of Hoxa9 (Montrer HOXA9 Anticorps) mRNA.

  4. Symplekin expression regulates the assembly of tight junctions, thus helps to maintain the integrity of the epithelial monolayer and cellular polarity.

  5. crystal structure at 2.4 A resolution of the amino-terminal domain (residues 30-340) of human symplekin in a ternary complex with the Pol II (Montrer 0 Anticorps) carboxy-terminal domain (CTD) Ser (Montrer SIGLEC1 Anticorps) 5 phosphatase Ssu72 (Montrer SSU72 Anticorps) and a CTD Ser (Montrer SIGLEC1 Anticorps) 5 phosphopeptide

  6. Symplekin supports faithful mitosis by contributing to the formation of a bipolar spindle apparatus. Depletion of symplekin attenuates microtubule polymerization as well as expression of the critical microtubule polymerization protein CKAP5 (TOGp (Montrer CKAP5 Anticorps)).

  7. Data show that claudin-2 (Montrer CLDN2 Anticorps) expression was reduced following symplekin down-regulation, and siRNA-mediated claudin-2 (Montrer CLDN2 Anticorps) down-regulation increased the transepithelial resistance and decreased cyclin D1 (Montrer CCND1 Anticorps) expression and ZONAB (Montrer CSDA Anticorps) nuclear localization.

  8. symplekin has a role in HSF1 (Montrer HSF1 Anticorps) modulation of Hsp70 (Montrer HSP70 Anticorps) mRNA polyadenylation

  9. The decreased expression of symplekin may be an early step in the transformation of hepatocytes, whereas alteration of the expression of adherens junctions and desmosomes may indicate more serious changes.

  10. The symplekin/ZONAB (Montrer CSDA Anticorps) complex inhibits intestinal cell differentiation by the repression of AML1/Runx1 (Montrer RUNX1 Anticorps).

Fruit Fly (Drosophila melanogaster) Symplekin (SYMPK) interaction partners

  1. Authors propose a model in which the core cleavage complex formation is mediated by CPSF73 (Montrer CPSF3 Anticorps), CPSF100 (Montrer CPSF2 Anticorps), and Symplekin C-termini, and the N-terminal region of Symplekin facilitates cotranscriptional 3' end processing of histone mRNAs.

  2. This localization depends on the RNA binding protein ypsilon schachtel. CPSF-73 (Montrer CPSF3 Anticorps) and a number of mRNAs are localized at this same site, suggesting that Symplekin participates in cytoplasmic polyadenylation at tricellular junctions.

  3. Together, these data support the conclusion that the Symplekin HEAT domain serves as a scaffold for protein-protein interactions essential to the mRNA maturation process.

Xenopus laevis Symplekin (SYMPK) interaction partners

  1. Here, we identify a new factor essential for polyadenylation, namely, symplekin, a CPEB and CPSF (Montrer CPSF2 Anticorps) binding protein that serves as a scaffold upon which regulatory factors are assembled

Arabidopsis thaliana Symplekin (SYMPK) interaction partners

Symplekin (SYMPK) profil antigène

Profil protéine

This gene encodes a nuclear protein that functions in the regulation of polyadenylation and promotes gene expression. The protein forms a high-molecular weight complex with components of the polyadenylation machinery. It is thought to serve as a scaffold for recruiting regulatory factors to the polyadenylation complex. It also participates in 3'-end maturation of histone mRNAs, which do not undergo polyadenylation. The protein also localizes to the cytoplasmic plaques of tight junctions in some cell types.

Gene names and symbols associated with anti-Symplekin (SYMPK) Anticorps

  • symplekin (SYMPK) anticorps
  • Symplekin (Sym) anticorps
  • symplekin (Sympk) anticorps
  • symplekin S homeolog (sympk.S) anticorps
  • symplekin (sympk) anticorps
  • symplekin (LOC552752) anticorps
  • symplekin (AT1G27595) anticorps
  • symplekin (LOC5580150) anticorps
  • symplekin (CpipJ_CPIJ011126) anticorps
  • Symplekin (Bm1_50390) anticorps
  • symplekin (NAEGRDRAFT_80124) anticorps
  • symplekin (LOAG_00841) anticorps
  • 1500016F02Rik anticorps
  • 4632415H16Rik anticorps
  • AA125406 anticorps
  • AI449890 anticorps
  • CG2097 anticorps
  • DKFZp468C0711 anticorps
  • Dmel\\CG2097 anticorps
  • dSymp anticorps
  • Hfn3g anticorps
  • MGC75595 anticorps
  • SPK anticorps
  • SYM anticorps
  • SYMPK anticorps
  • T22C5.3 anticorps

Protein level used designations for anti-Symplekin (SYMPK) Anticorps

CG2097-PA , Sym-PA , symplekin , hepatocyte nuclear factor 3 gamma , Symplekin , symplekin-like , LOW QUALITY PROTEIN: symplekin

GENE ID SPECIES
8189 Homo sapiens
40709 Drosophila melanogaster
68188 Mus musculus
292683 Rattus norvegicus
379378 Xenopus laevis
394872 Xenopus (Silurana) tropicalis
456142 Pan troglodytes
476431 Canis lupus familiaris
552752 Apis mellifera
839651 Arabidopsis thaliana
5580150 Aedes aegypti
6043768 Culex quinquefasciatus
6104963 Brugia malayi
8853240 Naegleria gruberi strain NEG-M
9938210 Loa loa
100010885 Monodelphis domestica
100070949 Equus caballus
100174376 Pongo abelii
100179022 Ciona intestinalis
100337373 Bos taurus
100348044 Oryctolagus cuniculus
100412467 Callithrix jacchus
100474335 Ailuropoda melanoleuca
100512609 Sus scrofa
100714088 Cavia porcellus
Fournisseurs de qualité sélectionnés pour anti-Symplekin (SYMPK) Anticorps
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