anti-Synapsin I (SYN1) Anticorps

SYN1 is a member of the synapsin gene family. De plus, nous expédions Synapsin I Kits (37) et Synapsin I Protéines (11) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
SYN1 6853 P17600
SYN1 24949 P09951
SYN1 20964 O88935
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Top anti-Synapsin I Anticorps sur anticorps-enligne.fr

Showing 10 out of 332 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Humain Souris Inconjugué WB SYN1 monoclonal antibody (M06), clone 4F6 Western Blot analysis of SYN1 expression in MCF-7. 100 μg Connectez-vous pour afficher 8 to 11 Days
$461.00
Détails
Humain Souris Inconjugué ELISA, WB SYN1 monoclonal antibody (M07), clone 4H1 Western Blot analysis of SYN1 expression in MCF-7. 100 μg Connectez-vous pour afficher 8 to 11 Days
$461.00
Détails
Humain Souris Inconjugué ELISA, FACS, ICC, IF, IHC, WB ELISA: Synapsin I Antibody (7H10G6)  - Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng) Flow Cytometry: Synapsin I Antibody (7H10G6)  - Analysis of Hela cells using SYN1 mouse mAb (green) and negative control (red). 0.1 mL Connectez-vous pour afficher 7 to 9 Days
$514.63
Détails
Humain Lapin Inconjugué IHC (p), WB Synapsin I was detected in paraffin-embedded sections of human glioma tissues using rabbit anti- Synapsin I Antigen Affinity purified polyclonal antibody (Catalog # ) at 1 ??g/mL. The immunohistochemical section was developed using SABC method (Catalog # SA1022). Western blot analysis of Synapsin I expression in rat brain extract ( Lane 1), mouse brain extract ( Lane 2), and SHG-44 whole cell lysates ( Lane 3). Synapsin I at 78KD was detected using rabbit anti- Synapsin I Antigen Affinity purified polyclonal antibody (Catalog # ) at 0.5 µg/mL. The blot was developed using chemiluminescence (ECL) method (Catalog # EK1002). 100 μg Connectez-vous pour afficher 4 to 6 Days
$280.00
Détails
Humain Lapin Inconjugué WB 100 μg Connectez-vous pour afficher 2 to 3 Days
$265.00
Détails
Humain Souris Inconjugué ELISA, ICC, WB Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng) Western blot analysis using SYN1 mAb against human SYN1 (AA: 362-511) recombinant protein. (Expected MW is 41.7 kDa) 0.1 mg Connectez-vous pour afficher 8 to 11 Days
$561.00
Détails
Humain Souris Inconjugué ELISA, FACS, ICC, IHC, WB Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng) Western blot analysis using SYN1 mAb against human SYN1 (AA: 362-511) recombinant protein. (Expected MW is 41.7 kDa) 0.1 mg Connectez-vous pour afficher 8 to 11 Days
$561.00
Détails
Rat Lapin Inconjugué WB Western blots of rat cortex lysate showing specific labeling of the ~78k synapsin protein phosphorylated at Ser 62,67 (Control). Immunolabeling is blocked by preadsorption with the phospho-peptide used as antigen (Peptide) but not by the corresponding dephospho-peptide (not shown). 100 μL Connectez-vous pour afficher 2 to 3 Days
$423.50
Détails
Boeuf (Vache) Lapin Inconjugué IC, IF, IHC, WB Immunofluorescent analysis of Synapsin 1 staining in MCF7 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary anti Immunohistochemical analysis of Synapsin 1 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with 200 μL Connectez-vous pour afficher 13 to 14 Days
$487.50
Détails
Boeuf (Vache) Lapin Inconjugué WB Western blot analysis of Synapsin 1 (pS553) expression in HEK293T (A), mouse brain (B), rat brain (C) whole cell lysates. 200 μL Connectez-vous pour afficher 13 to 14 Days
$575.00
Détails

SYN1 Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
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anti-Synapsin I Anticorps mieux référencés

  1. Human Polyclonal SYN1 Primary Antibody pour IHC - ABIN967122 : Sinha, Wang, Ruchalski, Levine, Krishnan, Lieberthal, Schwartz, Borkan: Lithium activates the Wnt and phosphatidylinositol 3-kinase Akt signaling pathways to promote cell survival in the absence of soluble survival factors. dans American journal of physiology. Renal physiology 2005 (PubMed)
    Show all 3 Pubmed References

  2. Human SYN1 Primary Antibody pour IHC - ABIN967121 : Bonanomi, Menegon, Miccio, Ferrari, Corradi, Kao, Benfenati, Valtorta: Phosphorylation of synapsin I by cAMP-dependent protein kinase controls synaptic vesicle dynamics in developing neurons. dans The Journal of neuroscience : the official journal of the Society for Neuroscience 2005 (PubMed)
    Show all 3 Pubmed References

  3. Rat (Rattus) Polyclonal SYN1 Primary Antibody pour WB - ABIN361494 : Jovanovic, Benfenati, Siow, Sihra, Sanghera, Pelech, Greengard, Czernik: Neurotrophins stimulate phosphorylation of synapsin I by MAP kinase and regulate synapsin I-actin interactions. dans Proceedings of the National Academy of Sciences of the United States of America 1996 (PubMed)
    Show all 9 Pubmed References

  4. Cow (Bovine) Polyclonal SYN1 Primary Antibody pour WB - ABIN2476654 : Chantler: Comparison of antihuman immunoglobulin and antihuman FAB conjugates for the detection of tissue autoantibodies by immunofluorescence. dans Annals of the New York Academy of Sciences 1975 (PubMed)
    Show all 3 Pubmed References

  5. Cow (Bovine) Polyclonal SYN1 Primary Antibody pour WB - ABIN2476655 : Jovanovic, Sihra, Nairn, Hemmings, Greengard, Czernik: Opposing changes in phosphorylation of specific sites in synapsin I during Ca2+-dependent glutamate release in isolated nerve terminals. dans The Journal of neuroscience : the official journal of the Society for Neuroscience 2001 (PubMed)
    Show all 3 Pubmed References

  6. Rat (Rattus) Polyclonal SYN1 Primary Antibody pour IHC, WB - ABIN361495 : Shulman, Stavsky, Fedorova, Mikulincer, Atias, Radinsky, Kahn, Slutsky, Gitler: ATP binding to synaspsin IIa regulates usage and clustering of vesicles in terminals of hippocampal neurons. dans The Journal of neuroscience : the official journal of the Society for Neuroscience 2015 (PubMed)
    Show all 9 Pubmed References

  7. Human Polyclonal SYN1 Primary Antibody pour IF (p), IHC (p) - ABIN747263 : Luo, Guo, Fan, Lu, Chen, Wang, Shao, Wu, Xu, Lü: Niche astrocytes promote the survival, proliferation and neuronal differentiation of co-transplanted neural stem cells following ischemic stroke in rats. dans Experimental and therapeutic medicine 2017 (PubMed)

  8. Cow (Bovine) Polyclonal SYN1 Primary Antibody pour WB - ABIN2476653 : Wang: [Treatment of severe chronic hepatitis B by combination of traditional Chinese medicine and Western medicine therapy--with an analysis of 122 cases]. dans Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine / Zhongguo Zhong xi yi jie he xue hui, Zhongguo Zhong yi yan jiu yuan zhu ban 1992 (PubMed)
    Show all 2 Pubmed References

  9. Rat (Rattus) Polyclonal SYN1 Primary Antibody pour IHC, WB - ABIN361492 : Dagyte, Luiten, De Jager, Gabriel, Mocaër, Den Boer, Van der Zee: Chronic stress and antidepressant agomelatine induce region-specific changes in synapsin I expression in the rat brain. dans Journal of neuroscience research 2011 (PubMed)

  10. Human Polyclonal SYN1 Primary Antibody pour ICC, IF - ABIN152646 : Hill, Mordes, Cameron, Neuberg, Landini, Eggan, Livingston: Two familial ALS proteins function in prevention/repair of transcription-associated DNA damage. dans Proceedings of the National Academy of Sciences of the United States of America 2016 (PubMed)

Plus d’anticorps contre Synapsin I partenaires d’interaction

Human Synapsin I (SYN1) interaction partners

  1. Authors identified the c.236 C > G/p.S79W mutation in SYN1 as causative for the non-syndromic ID of the MRX50 family. Accordingly, the in vitro characterization of S79W SynI clearly indicates that the mutation does not interfere with neurodevelopmental aspects, but perturbs spontaneous SV exocytosis, SV clustering and SV lateral mobility along axons.

  2. These findings contribute to previous work showing dysregulation of Synapsins, particularly SYN2 (Montrer SYN2 Anticorps), in mood disorders and improve our understanding of the regulatory mechanisms that precipitate these changes likely leading to the BD or MDD phenotype.

  3. Cerebral malaria causes pre-synaptic excitation and eventually activation of synapsin I, leading to increased neurotransmitter release.

  4. Patterns of the immunoreactivity with antibodies to SNAP-25 (Montrer SNAP25 Anticorps), synapsin-I and synaptophysin (Montrer SYP Anticorps) are completely appropriate to those of adult's OB on the 38-40 weeks of the prenatal development.

  5. The implementation of the AlphaScreen pSYN1 assay and future development of additional primary neuronal HTS (Montrer APCDD1 Anticorps) assays provides an attractive approach for discovery of novel classes of therapeutic candidates for a variety of CNS disorders.

  6. these findings suggest PRICKLE1 (Montrer PRICKLE1 Anticorps) mutations contribute to ASD (Montrer ARSD Anticorps) by disrupting the interaction with SYN1 and regulation of synaptic vesicles.

  7. Data indicate that in patients carrying the W356x mutation the function of synapsin I is markedly impaired, and support the value of Syn1(-/-) mice as an experimental model mimicking the human pathology.

  8. Epileptogenic Q555X SYN1 mutant triggers imbalances in release dynamics and short-term plasticity.

  9. The histone modification marks were significantly increased in major depression and this effect was correlated with significant increases in SYN1b gene expression.

  10. A conserved region of human and mouse SYN1 promoters contains cis (Montrer CISH Anticorps)-sites for the transcriptional activator Sp1 (Montrer PSG1 Anticorps) in close proximity to REST binding motifs.

Mouse (Murine) Synapsin I (SYN1) interaction partners

  1. Results implicate SYN1 in the pathogenesis of non-syndromic intellectual disability, showing that alterations of synaptic vesicle trafficking are one possible cause of this disease, and suggest that distinct mutations in SYN1 may lead to distinct brain pathologies.

  2. This study demonstrated that syn1 affect the rate of release of GABA quanta residing within the Hippocampal Interneurons.

  3. Synapsin I is localized and produced at mature axon terminals and at immature growth cones.

  4. HSV-1-infected neurons also exhibite significantly reduced expression of the presynaptic proteins synapsin-1 and synaptophysin. These effects depended on GSK-3 activation and intraneuronal accumulation of Ab

  5. Functions of synapsins in corticothalamic facilitation: important roles of synapsin I

  6. SynI mRNA and protein levels are down-regulated in the hippocampus of naive and Morris water maze-treated En2 (Montrer EN2 Anticorps)-/- mice.

  7. these findings suggest PRICKLE1 (Montrer PRICKLE1 Anticorps) mutations contribute to ASD (Montrer GUSB Anticorps) by disrupting the interaction with SYN1 and regulation of synaptic vesicles.

  8. during chronic modification of neuronal activity and is an essential downstream effector for the Cdk5 (Montrer CDK5 Anticorps)-mediated homeostatic scaling.

  9. O-GlcNAcylation of Thr (Montrer TRH Anticorps)-87 interferes with folding of the ALPS motif, providing a means for regulating the association of synapsin I with SVs (Montrer FGFR2 Anticorps) as a mechanism contributing to synapsin I localization and RPSV generation.

  10. Data indicate that in patients carrying the W356x mutation the function of synapsin I is markedly impaired, and support the value of Syn1(-/-) mice as an experimental model mimicking the human pathology.

Cow (Bovine) Synapsin I (SYN1) interaction partners

  1. These results raise the possibility that Ser (Montrer SIGLEC1 Anticorps)(603) on synapsin I is alternatively phosphorylated by p21 (Montrer CDKN1A Anticorps)-activated kinases, not only by CaMKII (Montrer CAMK2G Anticorps), in neuronal cells in response to some stimulants.

  2. Synapsin-Rab3 (Montrer RAB3A Anticorps) interaction may participate in the regulation of synaptic vesicle trafficking within the nerve terminals.

  3. Interacts with rab3 (Montrer RAB3A Anticorps) protein; this interaction is likely to play a major role in the modulation of neurotransmitter release.

Pig (Porcine) Synapsin I (SYN1) interaction partners

  1. This study reports molecular cloning and characterization of the coding sequence of the porcine ortholog of syn (Montrer SYNM Anticorps) I, including identification and verification at the protein level of an alanine-encoding insert.

Synapsin I (SYN1) profil antigène

Profil protéine

This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family plays a role in regulation of axonogenesis and synaptogenesis. The protein encoded serves as a substrate for several different protein kinases and phosphorylation may function in the regulation of this protein in the nerve terminal. Mutations in this gene may be associated with X-linked disorders with primary neuronal degeneration such as Rett syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.

Gene names and symbols associated with anti-Synapsin I (SYN1) Anticorps

  • synapsin I (SYN1) anticorps
  • synapsin I (Syn1) anticorps
  • synapsin I L homeolog (syn1.L) anticorps
  • synapsin I (syn1) anticorps
  • si:dkey-90n12.3 anticorps
  • Syn-1 anticorps
  • SYN1a anticorps
  • SYN1b anticorps
  • SYNI anticorps
  • SYN I anticorps

Protein level used designations for anti-Synapsin I (SYN1) Anticorps

brain protein 4.1 , synapsin-1 , synapsin 1 , synapsin I

GENE ID SPECIES
6853 Homo sapiens
24949 Rattus norvegicus
20964 Mus musculus
281510 Bos taurus
399153 Xenopus laevis
570672 Danio rerio
100017646 Monodelphis domestica
100216310 Sus scrofa
100685486 Canis lupus familiaris
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