anti-TAP Binding Protein (Tapasin) (TAPBP) Anticorps

TAPBP encodes a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. De plus, nous expédions TAPBP Kits (10) et TAPBP Protéines (7) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
TAPBP 21356 Q9R233
TAPBP 6892 O15533
TAPBP 25217  
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Top anti-TAPBP Anticorps sur anticorps-enligne.fr

Showing 10 out of 52 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué IHC, WB Human Skin 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Boeuf (Vache) Lapin Inconjugué WB WB Suggested Anti-TAPBP Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:62500  Positive Control:  OVCAR-3 cell lysate TAPBP is supported by BioGPS gene expression data to be expressed in OVCAR3 WB Suggested Anti-TAPBP <br /> Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.2500 <br /> Positive Control: OVCAR-3 cell lysate <br /> TAPBP is supported by BioGPS gene expression data to be expressed in OVCAR3 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Chien Lapin Inconjugué IHC, WB WB Suggested Anti-TAPBP Antibody Titration:  0.2-1 ug/ml  Positive Control:  293T cell lysate WB Suggested Anti-TAPBP <br /> Antibody Titration: 0.2-1 µg/mL <br /> Positive Control:.93T cell lysate 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Humain Lapin Inconjugué WB Western Blot: Tapasin Antibody [NBP1-59938] - Sample Type: Human Fetal Muscle Antibody Dilution: 1.0 ug/ml Western Blot: Tapasin Antibody [NBP1-59938] - Sample Type: Human Adult Placenta Antibody Dilution: 1.0 ug/ml 100 μL Connectez-vous pour afficher 8 to 11 Days
$485.88
Détails
Humain Lapin Inconjugué IHC, WB Western blot analysis of extracts of HT-29 cells, using TAPBP antibody (ABIN5971019) at 1/1000 dilution. Immunohistochemistry of paraffin-embedded human stomach using TAPBP Antibody (ABIN5971019) at dilution of 1/200 (40x lens). 100 μL Connectez-vous pour afficher 11 to 16 Days
$426.40
Détails
Boeuf (Vache) Lapin Inconjugué WB 50 μg Connectez-vous pour afficher 11 to 14 Days
$551.83
Détails
Humain Lapin Inconjugué WB 50 μg Connectez-vous pour afficher 11 to 14 Days
$551.83
Détails
Boeuf (Vache) Lapin Inconjugué IHC, IHC (p), WB Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE) Anti-TAPBP / Tapasin antibody IHC staining of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml. This image was taken for the unconjugated fo ... 50 μg Connectez-vous pour afficher 11 to 14 Days
$727.83
Détails
Humain Lapin Inconjugué ELISA, IHC, WB Western blot analysis of A431 cell lysate, using TAPBP Antibody. The lane on the left is treated with the antigen-specific peptide. ABIN6276986 at 1/100 staining Rat colon tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22¡ãC. An HRP conjugated goat anti-rabbit antibody was used as the secondary 100 μL Connectez-vous pour afficher 11 to 12 Days
$390.77
Détails
Humain Lapin Inconjugué WB TAPBP Antibody (N-term)  western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the TAPBP antibody detected the TAPBP protein (arrow). 400 μL Connectez-vous pour afficher 10 to 11 Days
$335.50
Détails

anti-TAPBP Anticorps mieux référencés

  1. Human Polyclonal TAPBP Primary Antibody pour IHC, IHC (p) - ABIN4357823 : Sokol, Koelzer, Rau, Karamitopoulou, Zlobec, Lugli: Loss of tapasin correlates with diminished CD8(+) T-cell immunity and prognosis in colorectal cancer. dans Journal of translational medicine 2015 (PubMed)

Plus d’anticorps contre TAPBP partenaires d’interaction

Mouse (Murine) TAP Binding Protein (Tapasin) (TAPBP) interaction partners

  1. Absence of Tpn or ERAAP independently altered the peptide repertoire by causing loss as well as gain of new pMHC I. Tpn defined the characteristic carboxy termini of canonical MHC I peptides.

  2. modification of Tapasin can enhance the presentation of targeting antigens via intracellular delivery to DCs and elicit specific CTL immune responses efficiently

  3. Data show that tapasin expression is enhanced by beta 2-microglobulin (Montrer B2M Anticorps) via both transcriptional and post-transcriptional mechanisms.

  4. Deletion of a loop within the tapasin C-terminal Ig-like domain (Delta334-342) prevented tapasin association with the MHC class I molecule K(d).

  5. E2F1 (Montrer E2F1 Anticorps) is an essential transcription factor for tapasin.

  6. showed that a large disulfide-bonded complex was present in the mouse cells that included ERp57 (Montrer PDIA3 Anticorps), tapasin, and K(d).

  7. Role of tapasin in MHC class I antigen presentation in vivo.

  8. Data show that cell surface expression of TAP-independent class I complexes is modulated by tapasin levels and is enhanced by interferon-gamma (Montrer IFNG Anticorps).

  9. tapasin has a essential function of tapasin in quality control of HLA-G (Montrer HLAG Anticorps) molecules

  10. A major role for tapasin as a stabilizer of the TAP peptide transporter and consequences for MHC class I expression.

Human TAP Binding Protein (Tapasin) (TAPBP) interaction partners

  1. The results demonstrated that the mRNA expression levels of tapasin were significantly downregulated in patients with chronic hepatitis B (CHB) compared with in healthy controls and patients with acute hepatitis B Furthermore, the apoptotic rate of CD8 (Montrer CD8A Anticorps)+ T cells was increased in patients with CHB compared with in the other two groups.

  2. The disruption of TAP1 (Montrer TAP1 Anticorps) and TAPBP generates pluripotent embryonic stem cells with reduced immunogenicity.

  3. Fluctuation and entropy analyses show how tapasin chaperones major histocompatibility complex class I by stabilising it in a peptide-receptive conformation.

  4. reduction in tapasin expression is associated with tumor progression in colorectal cancer

  5. Data suggest that tapasin (Tsn) binds to MHC I with suboptimal cargo and thereby adjusts the energy landscape in favor of MHC I complexes with immunodominant epitopes.

  6. TAP/TPN complex formation is driven by hydrophobic interactions via leucine zipper-like motifs.

  7. TAP2 (Montrer TAP2 Anticorps), HLA-DOA (Montrer HLA-DOA Anticorps), HLA-DOB (Montrer HLA-DOB Anticorps), and tapasin loci are novel candidate regions for susceptibility to HCV infection and viral clearance in the Chinese population

  8. Analysis of expression of tapasin and/or HLA-I may be of value as prognostic tool for glioblastoma multiforme patients, especially when considering immunotherapy.

  9. Modified TAPBP gene function may contribute to the development of refractory chronic rhinosinusitis via reduction of circulating CD8 (Montrer CD8A Anticorps) lymphocytes.

  10. Targeted re-sequencing identified rs3106189 at the 5' UTR (Montrer UTS2R Anticorps) of TAPBP and rs1052918 at the 3' UTR (Montrer UTS2R Anticorps) of TCF3 (Montrer TCF3 Anticorps) to be associated with the overall survival of colorectal cancer patients.

TAPBP profil antigène

Profil protéine

This gene encodes a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum. This gene lies within the major histocompatibility complex on chromosome 6. Alternative splicing results in three transcript variants encoding different isoforms.

Gene names and symbols associated with TAPBP

  • TAP binding protein (tapasin), tandem duplicate 1 (tapbp.1) anticorps
  • TAP binding protein (tapbp) anticorps
  • TAP binding protein (TAPBP) anticorps
  • TAP binding protein (Tapbp) anticorps
  • D17Wsu91e anticorps
  • mhc1uda anticorps
  • mhc1ufa anticorps
  • NGS17 anticorps
  • SI:dZ179B20.1 anticorps
  • SI:dZ179B20.3 anticorps
  • SI:dZ179B20.7 anticorps
  • TAPA anticorps
  • TAPBP anticorps
  • TPN anticorps
  • TPSN anticorps
  • zgc:109814 anticorps

Protein level used designations for TAPBP

tapasin , TAP binding protein , TAP-associated protein , TAP-binding protein , TPSN , NGS-17 , TPN

GENE ID SPECIES
30163 Danio rerio
100136493 Salmo salar
100170652 Ovis aries
21356 Mus musculus
6892 Homo sapiens
504335 Bos taurus
25217 Rattus norvegicus
417048 Gallus gallus
481740 Canis lupus familiaris
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