anti-TIMP Metallopeptidase Inhibitor 3 (TIMP3) Anticorps

TIMP3 belongs to the TIMP gene family. De plus, nous expédions TIMP3 Kits (98) et TIMP3 Protéines (17) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
TIMP3 7078 P35625
TIMP3 25358  
TIMP3 21859 P39876
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Top anti-TIMP3 Anticorps sur anticorps-enligne.fr

Showing 10 out of 215 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB <b>WB Suggested Anti-TIMP3 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:1562500<br><b>Positive Control: </b>MCF7 cell lysate WB Suggested Anti-TIMP3 <br /> Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:1562500 <br /> Positive Control: MCF7 cell lysate 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Boeuf (Vache) Lapin Inconjugué IHC, WB <b>WB Suggested Anti-TIMP3 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:1562500<br><b>Positive Control: </b>MCF7 cell lysate WB Suggested Anti-TIMP3 <br /> Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:1562500 <br /> Positive Control: MCF7 cell lysate 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Humain Lapin Inconjugué ELISA, WB Western blot analysis of TIMP3 using anti- TIMP3 antibody .  Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each  Lane was loaded with 50ug of sample under reducing conditions.   Lane 1: rat kidney tissue lysates,   Lane 2: NIH3T3 whole cell lysates.  After Electrophoresis, proteins were transferred to a Nitrocellulose membrane at 150mA for 50-90 minutes. Blocked the membrane with 5% Non-fat Milk/ TBS for 1.5 hour at RT. The membrane was incubated with rabbit anti- TIMP3 antigen affinity purified polyclonal antibody (Catalog # ) at 0.5 µg/mL overnight at 4°C, then washed with TBS-0.1%Tween 3 times with 5 minutes each and probed with a goat anti-rabbit IgG-HRP secondary antibody at a dilution of 1:10000 for 1.5 hour at RT. The signal is developed using an Enhanced Chemiluminescent detection (ECL) kit (Catalog # EK1002) with Tanon 5200 system. A specific band was detected for TIMP3 at approximately 24KD. The expected band size for TIMP3 is at 24KD. 100 μg Connectez-vous pour afficher 4 to 6 Days
$240.00
Détails
Boeuf (Vache) Lapin Inconjugué WB Western blot analysis of TIMP3 expression in HepG2 (A), HeLa (B), NIH3T3 (C) whole cell lysates. 200 μL Connectez-vous pour afficher 13 to 14 Days
$487.50
Détails
Humain Lapin Inconjugué ELISA, WB 100 μg Connectez-vous pour afficher 4 to 6 Days
$240.00
Détails
Humain Lapin Inconjugué ELISA, WB Western blot analysis of extracts from HuvEc cells, using TIMP3 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Connectez-vous pour afficher 2 to 3 Days
$302.50
Détails
Humain Lapin Inconjugué IF (p), IHC (p), WB Formalin-fixed and paraffin embedded mouse liver tissue labeled with Anti-TIMP-3 Polyclonal Antibody (ABIN668361), Unconjugated at 1:100, followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded mouse liver tissue labeled with Anti-TIMP-3 Polyclonal Antibody , Unconjugated at 1:100, followed by conjugation to the secondary antibody and DAB staining 100 μL Connectez-vous pour afficher 3 to 7 Days
$318.45
Détails
Humain Lapin Inconjugué EIA, FACS, IHC (p), WB TIMP3 Antibody (Center) flow cytometric analysis of MCF-7 cells (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. Formalin-fixed and paraffin-embedded human breast carcinoma reacted with TIMP3 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. 0.4 mL Connectez-vous pour afficher 6 to 8 Days
$390.50
Détails
Boeuf (Vache) Lapin APC FACS, IF, IHC (f) 250 μL Connectez-vous pour afficher 3 to 4 Days
$392.62
Détails
Boeuf (Vache) Lapin PerCP FACS, IF, IHC (f) 250 μL Connectez-vous pour afficher 3 to 4 Days
$392.62
Détails

anti-TIMP3 Anticorps mieux référencés

  1. Human Polyclonal TIMP3 Primary Antibody pour IF (p), IHC (p) - ABIN668361 : Liu, Cui, Ao, Zhou, Zhou, Yuan, Xiang, Liu, Cao et al.: Aberrant methylation accounts for cell adhesion-related gene silencing during 3-methylcholanthrene and diethylnitrosamine induced multistep rat lung carcinogenesis associated with overexpression of ... dans Toxicology and applied pharmacology 2011 (PubMed)
    Show all 5 Pubmed References

  2. Human Monoclonal TIMP3 Primary Antibody pour IHC (p), IHC - ABIN258856 : Jerónimo, Rodrigues, Vilas-Boas, Martins, Bagulho, Real: Hydrogen peroxide regulates angiogenesis-related factors in tumor cells. dans Biochemistry and cell biology = Biochimie et biologie cellulaire 2017 (PubMed)

  3. Human Polyclonal TIMP3 Primary Antibody pour ELISA, ICC - ABIN6265583 : Mao, Du, Yang, Zhang, Peng, Jiang, Zhou: Inhibitors of PARP-1 exert inhibitory effects on the biological characteristics of hepatocellular carcinoma cells in vitro. dans Molecular medicine reports 2018 (PubMed)

  4. Human Monoclonal TIMP3 Primary Antibody pour FACS - ABIN4896675 : Mahller, Vaikunth, Ripberger, Baird, Saeki, Cancelas, Crombleholme, Cripe: Tissue inhibitor of metalloproteinase-3 via oncolytic herpesvirus inhibits tumor growth and vascular progenitors. dans Cancer research 2008 (PubMed)

  5. Human Monoclonal TIMP3 Primary Antibody pour CyTOF, FACS - ABIN4899802 : Troeberg, Fushimi, Khokha, Emonard, Ghosh, Nagase: Calcium pentosan polysulfate is a multifaceted exosite inhibitor of aggrecanases. dans FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008 (PubMed)

Plus d’anticorps contre TIMP3 partenaires d’interaction

Human TIMP Metallopeptidase Inhibitor 3 (TIMP3) interaction partners

  1. miR (Montrer MLXIP Anticorps)-21-5p mediates apoptosis by targeting PTEN and TIMP3.

  2. Preliminary studies indicate that baseline MMP3 (Montrer MMP3 Anticorps) and TIMP3 concentrations are associated with patient survival and disease-free time

  3. TIMP-3 mRNA expression levels positively correlates with levels of miR (Montrer MLXIP Anticorps)-21 in in situ breast carcinomas and negatively in progesterone receptor (Montrer PGR Anticorps) positive invasive breast carcinomas.

  4. Sphingosine-1-phosphate inhibited cell migration and MMP-2 (Montrer MMP2 Anticorps) expression through the upregulation of the tissue inhibitor of metalloproteinase-3 (TIMP-3) expression in human chondrosarcoma cells.

  5. Using global proteomic profiling of brain leptomeningeal arteries, this study revealed that clusterin (Montrer CLU Anticorps) and tissue inhibitor of metalloproteinases-3 increase in leptomeningeal arteries affected by cerebral amyloid angiopathy.

  6. This is the first report of a syndromic Sorsby fundus dystrophy in line with the mouse model uncovering the role of TIMP3 in human lung morphogenesis and functions.

  7. Collectively, these results demonstrated that IL-32alpha upregulates the atheroprotective genes Timp3 and Reck (Montrer RECK Anticorps) by downregulating microRNA-205 through regulation of the Rprd2-Dgcr8 (Montrer DGCR8 Anticorps)/Ddx5 (Montrer DDX5 Anticorps)-Dicer1 (Montrer DICER1 Anticorps) biogenesis pathway.

  8. MMP-13 (Montrer MMP13 Anticorps) may play a role on physiological turnover of cartilage extracellular matrix and that LRP1 (Montrer LRP1 Anticorps) is a key modulator of extracellular levels of MMP-13 (Montrer MMP13 Anticorps) and its internalization is independent of the levels of ADAMTS-4 (Montrer ADAMTS4 Anticorps), -5 and TIMP-3.

  9. Long noncoding RNA DANCR promotes prostate cancer invasion and metastasis through repressing the expression of TIMP2 (Montrer TIMP2 Anticorps)/3

  10. we show that KDM1A (Montrer KDM1A Anticorps) promotes cancer metastasis in non-small cell lung cancer cells by repressing TIMP3 (tissue inhibitor of metalloproteinase 3) expression.

Rabbit TIMP Metallopeptidase Inhibitor 3 (TIMP3) interaction partners

  1. The present study demonstrated the ability of 30 and 100 ng/ml TIMP3 to attenuate migration and proliferation, and to inhibit the activity of MMP2 (Montrer MMP2 Anticorps), MMP9 (Montrer MMP9 Anticorps) and TNFalpha (Montrer TNF Anticorps) secretion of NA SMCs. In conclusion, TIMP3 may be considered a potential therapeutic drug for use in a novel drugeluting stent, to attenuate the progressive dilation of the aortic NA.

  2. Circulating smoke components, including acrolein, contribute to vascular diseases through enhanced MMP-1 (Montrer MMP1 Anticorps) and decreased TIMP-3 secretion.

  3. TIMP-3 is downregulated in a distinct subpopulation of atherosclerotic foam cells which have increased MMP-14 (Montrer MMP14 Anticorps).

Cow (Bovine) TIMP Metallopeptidase Inhibitor 3 (TIMP3) interaction partners

  1. Reactive oxygen species mediate TGF-beta1 (Montrer TGFB1 Anticorps)-induced TIMP-3 gene expression

  2. TIMP3 has a role in the pericyte-induced stabilization of newly formed vascular networks that are predisposed to undergo regression and reveal specific molecular targets of the inhibitors regulating these events.

  3. TIMP3 mRNA expression level was upregulated by multidirectional articular motion.

Xenopus laevis TIMP Metallopeptidase Inhibitor 3 (TIMP3) interaction partners

  1. only the N-terminal, but not the C-terminal domain of TIMP-3, results in developmental defects.

  2. metamorphic tail and intestine RNA levels of TIMP-2 (Montrer TIMP2 Anticorps), MT1-MMP (Montrer MMP14 Anticorps) and Gel-A, but not MT3-MMP (Montrer MMP24 Anticorps) or TIMP-3, are elevated during periods of cell death and proliferation

Mouse (Murine) TIMP Metallopeptidase Inhibitor 3 (TIMP3) interaction partners

  1. Loss of TIMP3 is associated with germinal matrix hemorrhage-intraventricular hemorrhage.

  2. altered cortical and trabecular bone mineralization and increased compositional heterogeneity were found in Timp-3 (-/-) bone, all being indicative of high bone remodeling

  3. In a clinically relevant CADASIL (Montrer NOTCH3 Anticorps) mouse model, we show that exogenous ADAM17 (Montrer ADAM17 Anticorps) or HB-EGF (Montrer HBEGF Anticorps) restores cerebral arterial tone and blood flow responses, and identify upregulated voltage-dependent potassium channel (Montrer KCNAB2 Anticorps) (KV) number in cerebral arterial myocytes as a heretofore-unrecognized downstream effector of TIMP3-induced deficits.

  4. TIMP3 promotes normal microvascular endothelial cell barrier function, at least partially, through inhibition of metalloproteinase-dependent disruption of adherens junctions, and septic downregulation of TIMP3 may contribute to septic MVEC barrier dysfunction.

  5. data strongly suggest that TIMP3 has direct neuroprotective effects that can mitigate the deleterious effects associated with TBI, an area with few if any therapeutic options.

  6. Elevated levels of TIMP3 and vitronectin (Montrer VTN Anticorps), acting downstream of Notch3 (Montrer NOTCH3 Anticorps)(ECD (Montrer ECD Anticorps)) deposition, play a role in CADASIL (Montrer NOTCH3 Anticorps), producing divergent influences on early CBF (Montrer CEBPZ Anticorps) deficits and later white matter lesions.

  7. 4-Hydroxyisoleucine improved insulin (Montrer INS Anticorps) resistant-like state in 3T3-L1 adipocytes by targeting TACE (Montrer ADAM17 Anticorps)/TIMP3 and the insulin (Montrer INS Anticorps) signaling pathway.

  8. In a mouse model of prostate cancer, increased tumor growth, proliferation index, increased microvascular density, and invasion was observed in Pten(-/-), Timp3(-/-) prostate tumors compared to Pten(-/-), Timp3(+/+) tumors.

  9. Timp3 status determines p53 (Montrer TP53 Anticorps), p38 (Montrer CRK Anticorps) and Notch (Montrer NOTCH1 Anticorps) coactivation to instruct hepatic cell fate and transformation.

  10. TIMP2 (Montrer TIMP2 Anticorps) and TIMP3 play fundamental and differential roles in mediating pathological remodelling, independent from their MMP-inhibitory function

Pig (Porcine) TIMP Metallopeptidase Inhibitor 3 (TIMP3) interaction partners

  1. These results suggest the crucial role of TIMP-3 in successful implantation and embryo survival and indicate the endometrial stromal decidualization-like in pigs.

TIMP3 profil antigène

Profil protéine

This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix (ECM). Expression of this gene is induced in response to mitogenic stimulation and this netrin domain-containing protein is localized to the ECM. Mutations in this gene have been associated with the autosomal dominant disorder Sorsby's fundus dystrophy.

Gene names and symbols associated with TIMP3

  • metalloproteinase inhibitor 3 (CpipJ_CPIJ003282) anticorps
  • TIMP metallopeptidase inhibitor 3 (TIMP3) anticorps
  • Metalloproteinase inhibitor 3 (timp3) anticorps
  • TIMP metallopeptidase inhibitor 3 (Timp3) anticorps
  • TIMP metallopeptidase inhibitor 3 L homeolog (timp3.L) anticorps
  • tissue inhibitor of metalloproteinase 3 (Timp3) anticorps
  • HSMRK222 anticorps
  • IMP-3 anticorps
  • K222 anticorps
  • K222TA2 anticorps
  • SFD anticorps
  • Timp-3 anticorps
  • timp3 anticorps
  • timp3-A anticorps

Protein level used designations for TIMP3

metalloproteinase inhibitor 3 , TIMP metallopeptidase inhibitor 3 (Sorsby fundus dystrophy, pseudoinflammatory) , tissue inhibitor metalloproteinase-3 , TIMP metallopeptidase inhibitor 3 , Metalloproteinase inhibitor 3 , MIG-5 protein , TIMP-3 , protein MIG-5 , tissue inhibitor of metalloproteinases 3 , tissue inhibitor of metalloproteinase-3 , tissue inhibitor of metalloproteinase 3 (Sorsby fundus dystrophy, pseudoinflammatory) , tissue inhibitor of metalloproteinase 3 , 21 kDa protein of extracellular matrix , tissue inhibitor of metalloproteinases-3

GENE ID SPECIES
6034728 Culex quinquefasciatus
481289 Canis lupus familiaris
100135460 Papio anubis
100196821 Salmo salar
7078 Homo sapiens
100008690 Oryctolagus cuniculus
25358 Rattus norvegicus
282094 Bos taurus
100033947 Equus caballus
396483 Gallus gallus
373596 Xenopus laevis
574381 Macaca mulatta
100217407 Ovis aries
21859 Mus musculus
396775 Sus scrofa
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