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Promotes FBN1 matrix assembly. De plus, nous expédions Thrombospondin, Type I, Domain Containing 4 Kits (1) et beaucoup plus de produits pour cette protéine.
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In breast cancer, some GATA3 effects shift from tumor suppressing to tumor promoting during tumorigenesis, with deregulation of three genes, BCL2, DACH1, THSD4, representing major GATA3-controlled processes in cancer progression.
ADAMTSL6beta has a role in fibrillin-1 microfibril formation
THSD4 polymorphism was not found to be associated with COPD risk
Data show expression of TNS1, GSTCD, AGER, HTR4 and THSD4 in lung tissue and indicate potential targets for interventions to alleviate respiratory disease.
Variations may be important determinants of osteoporosis in Japanese women.
Results indicated that ADAMTSL-6 is a novel microfibril-associated protein that binds directly to fibrillin-1 and promotes fibrillin-1 matrix assembly.
Promotes FBN1 matrix assembly. Attenuates TGFB signaling, possibly by accelerating the sequestration of large latent complexes of TGFB or active TGFB by FBN1 microfibril assembly, thereby negatively regulating the expression of TGFB regulatory targets, such as POSTN.
A disintegrin and metalloproteinase with thrombospondin motifs-like protein 6
, ADAMTS-like protein 6
, thrombospondin type-1 domain-containing protein 4
, ADAMTS-like protein 4