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TBL2 encodes a member of the beta-transducin protein family. De plus, nous expédions Transducin (Beta)-Like 2 Protéines (4) et et beaucoup plus de produits pour cette protéine.
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TBL2 participates in ATF4 translation through its association with the mRNA.
association of TBL2 with the 60S subunit was ER stress independent while the TBL2-PERK interaction occurred upon ER stress
TBL2 interacts with PERK via the N-terminus proximal region and also associates with eIF2a via the WD40 domain thus modulating stress-signaling and cell survival during endoplasmic reticulum stress.
A TERE1-TBL2 complex likely functions in oxidative/nitrosative stress, lipid metabolism, and SXR signaling pathways in its role as a tumor suppressor.
Data show that SNPs associated with TG in normolipidemic samples, including APOA5, TRIB1, TBL2, GCKR, GALNT2 and ANGPTL3 were significantly associated with HLP types 2B, 3, 4 and 5.
This gene encodes a member of the beta-transducin protein family. Most proteins of the beta-transducin family are involved in regulatory functions. This protein is possibly involved in some intracellular signaling pathway. This gene is deleted in Williams-Beuren syndrome, a developmental disorder caused by deletion of multiple genes at 7q11.23.
transducin (beta)-like 2
, transducin beta-like protein 2-like
, WS beta-transducin repeats protein
, Williams-Beuren syndrome chromosome region 13
, transducin beta-like protein 2