anti-Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2) Anticorps

TGFBR2 encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily.

afficher tous les anticorps Gène GeneID UniProt
Anti-Humain TGFBR2 TGFBR2 7048 P37173
Anti-Souris TGFBR2 TGFBR2 21813 Q62312
Anti-Rat TGFBR2 TGFBR2 81810 P38438
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Top anti-TGFBR2 Anticorps sur anticorps-enligne.fr

Showing 10 out of 230 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Humain Chèvre Inconjugué CyTOF, ELISA (Capture), FACS, IHC, Neut, WB Detection of TGF-beta RII in Human Lymphocytes by Flow Cytometry. Human blood-derived lymphocytes were labeled with Goat Anti-Human TGF-beta RII Antigen Affinity-purified Poly-clonal Antibody. TGF-beta RII in Human Pituitary. TGF-beta RII was detected in immersion fixed paraffin-embedded sections of human pituitary using Goat Anti-Human TGF-beta RII Antigen Affinity-purified Polyclonal Antibody. Lower panel shows a lack of labeling if primary antibodies are omitted and tissue is stained only with secondary antibody followed by incubation with detection reagents. 250 μg Connectez-vous pour afficher 8 to 9 Days
$463.45
Détails
Humain Lapin Inconjugué WB 100 μg Connectez-vous pour afficher 4 to 6 Days
$240.00
Détails
Boeuf (Vache) Lapin Inconjugué WB WB Suggested Anti-TGFBR2 Antibody Titration:  5.0ug/ml  Positive Control:  HepG2 cell lysate TGFBR2 is strongly supported by BioGPS gene expression data to be expressed in Human HepG2 cells Host:  Mouse  Target Name:  TGFBR2  Sample Tissue:  Mouse Spleen  Antibody Dilution:  1ug/ml 100 μL Connectez-vous pour afficher 2 to 3 Days
$229.00
Détails
Humain Lapin Inconjugué WB Western blot analysis of TGFBR2 expression in HepG2 (A), A549 (B), TF1 (C), KNRK (D) whole cell lysates. 200 μL Connectez-vous pour afficher 13 to 14 Days
$487.50
Détails
Humain Lapin Inconjugué WB Western blot analysis of TGFBR2 (pS225) expression in A549 (A), NIH3T3L1 (B), KNRK (C), HepG2 (D) whole cell lysates. 200 μL Connectez-vous pour afficher 13 to 14 Days
$575.00
Détails
Souris Chèvre PE FACS Detection of TGF-beta RII in Mouse Splenocytes by Flow Cytometry. Mouse splenocytes were stained with Goat Anti-Mouse TGF-beta RII PE-conjugated Antigen Affinity-purified Polyclonal Antibody. 100 Tests Connectez-vous pour afficher 8 to 9 Days
$334.65
Détails
Humain Lapin Inconjugué IHC, ELISA, WB The TGF-beta Receptor Type II Antibody is used in Western blot to detect TGF-beta receptor type II in rat brain lysates. TGF-beta Receptor Type II staining in rat colon. Paraffin-embedded rat colon is stained with TGF-beta Receptor Type II Antibody used at 1:200 dilution. 0.1 mg Connectez-vous pour afficher 2 to 6 Days
$377.30
Détails
Humain Lapin Inconjugué IHC, WB Immunohistochemical analysis of TGFBR2 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the Western blot analysis of TGFBR2 expression in A549 (A), NIH3T3 (B) whole cell lysates. 200 μL Connectez-vous pour afficher 13 to 14 Days
$487.50
Détails
Humain Lapin Inconjugué IHC, WB 100 μg Connectez-vous pour afficher 2 to 3 Days
$245.00
Détails
Humain Lapin Inconjugué ELISA, WB Western blot analysis of extracts from HepG2 (65K)  cells, using TGF beta Receptor II Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Connectez-vous pour afficher 2 to 3 Days
$302.50
Détails

anti-TGFBR2 Anticorps mieux référencés

  1. Human Polyclonal TGFBR2 Primary Antibody pour CyTOF, ELISA (Capture) - ABIN4900595 : Wu, Majeed, Evans, Camus, Wong, Schollmeier, Park, Muppidi, Reboldi, Parham, Cyster, Brodsky: Clathrin light chains' role in selective endocytosis influences antibody isotype switching. dans Proceedings of the National Academy of Sciences of the United States of America 2016 (PubMed)
    Show all 16 Pubmed References

  2. Mouse (Murine) Polyclonal TGFBR2 Primary Antibody pour FACS - ABIN4898046 : Lewis, Macal, Hesser, Zuñiga et al.: Constitutive but not inducible attenuation of transforming growth factor β signaling increases natural killer cell responses without directly affecting dendritic cells early after persistent viral ... dans Journal of virology 2015 (PubMed)
    Show all 6 Pubmed References

  3. Mouse (Murine) Polyclonal TGFBR2 Primary Antibody pour CyTOF, FACS - ABIN4900597 : Liu, Bi, Xue, Zhang, Yang, Chen, Lu, Zhang, Liu, Wang, Wang, Chu, Yang: Dendritic cell SIRT1-HIF1α axis programs the differentiation of CD4+ T cells through IL-12 and TGF-β1. dans Proceedings of the National Academy of Sciences of the United States of America 2015 (PubMed)
    Show all 4 Pubmed References

  4. Mouse (Murine) Polyclonal TGFBR2 Primary Antibody pour FACS, WB - ABIN4900596 : Denton, Zheng, Evans, Shi-wen, Ong, Fisher, Lazaridis, Abraham, Black, de Crombrugghe et al.: Fibroblast-specific expression of a kinase-deficient type II transforming growth factor beta (TGFbeta) receptor leads to paradoxical activation of TGFbeta signaling pathways with fibrosis in ... dans The Journal of biological chemistry 2003 (PubMed)
    Show all 4 Pubmed References

  5. Human Polyclonal TGFBR2 Primary Antibody pour IF (p), IHC (p) - ABIN725225 : Abdelmagid, Belcher, Moussa, Lababidi, Sondag, Novak, Sanyurah, Frara, Razmpour, Del Carpio-Cano, Safadi: Mutation in osteoactivin decreases bone formation in vivo and osteoblast differentiation in vitro. dans The American journal of pathology 2014 (PubMed)
    Show all 3 Pubmed References

  6. Mouse (Murine) Polyclonal TGFBR2 Primary Antibody pour FACS - ABIN4898038 : Gallo, Loch, Habashi, Calderon, Chen, Bedja, van Erp, Gerber, Parker, Sauls, Judge, Cooke, Lindsay, Rouf, Myers, ap Rhys, Kent, Norris, Huso, Dietz: Angiotensin II-dependent TGF-β signaling contributes to Loeys-Dietz syndrome vascular pathogenesis. dans The Journal of clinical investigation 2014 (PubMed)
    Show all 2 Pubmed References

  7. Human Polyclonal TGFBR2 Primary Antibody pour ICC, IHC (fro) - ABIN407857 : Phatnani, Guarnieri, Friedman, Carrasco, Muratet, OKeeffe, Nwakeze, Pauli-Behn, Newberry, Meadows, Tapia, Myers, Maniatis: Intricate interplay between astrocytes and motor neurons in ALS. dans Proceedings of the National Academy of Sciences of the United States of America 2013 (PubMed)
    Show all 2 Pubmed References

  8. Human Polyclonal TGFBR2 Primary Antibody pour IHC, ELISA - ABIN1585382 : Li, Martijn, Cui, Essaghir, Luque, Demoulin, Castaño, Öberg, Giandomenico: The somatostatin analogue octreotide inhibits growth of small intestine neuroendocrine tumour cells. dans PLoS ONE 2012 (PubMed)
    Show all 2 Pubmed References

  9. Human Polyclonal TGFBR2 Primary Antibody pour FACS - ABIN4898026 : Rani, Smulian, Greaves, Hogan, Herbert: TGF-β limits IL-33 production and promotes the resolution of colitis through regulation of macrophage function. dans European journal of immunology 2011 (PubMed)

  10. Human Monoclonal TGFBR2 Primary Antibody pour FACS - ABIN4898032 : Hermitte, Brunet de la Grange, Belloc, Praloran, Ivanovic: Very low O2 concentration (0.1%) favors G0 return of dividing CD34+ cells. dans Stem cells (Dayton, Ohio) 2006 (PubMed)

Plus d’anticorps contre TGFBR2 partenaires d’interaction

Human Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2) interaction partners

  1. TGFBR1 (Montrer TGFBR1 Anticorps)/2 genetic variants (in particular when evaluated as a burden by score) might play a role in modulating the severity of cardiovascular manifestation in Marfan syndrome.

  2. Down-regulation of TGF-beta (Montrer TGFB1 Anticorps) RII was found in the invasive non-functioning pituitary adenomas compared to noninvasive ones.

  3. findings reveal a novel role for miR (Montrer MLXIP Anticorps)-204/ANGPT1 (Montrer ANGPT1 Anticorps)/TGFbetaR2 axis in tumor angiogenesis. We propose that therapeutic manipulation of miR (Montrer MLXIP Anticorps)-204 levels may represent a promising approach in breast cancer.

  4. Proteotoxic stress suppressed TGFb (Montrer TGFB1 Anticorps)-induced EMT (Montrer ITK Anticorps) through downregulation of TGFbR-II and subsequent blockade of Smad2 (Montrer SMAD2 Anticorps), ERK1/2, and FAK (Montrer PTK2 Anticorps) activation.

  5. High TGFBR2 expression is associated with small cell lung cancer.

  6. expression induced by IL-6 (Montrer IL6 Anticorps) in keratinocytes

  7. hsa (Montrer CD24 Anticorps)-miR (Montrer MLXIP Anticorps)-1193 may be involved in sporadic colorectal cancer tumourigenesis at least in part by suppression of TGFBR2, and the A allele of rs11466537 disturbed the regulation of hsa (Montrer CD24 Anticorps)-miR (Montrer MLXIP Anticorps)-1193 on TGFBR2.

  8. DZNep induced miR (Montrer MLXIP Anticorps)-202-5p to target both TGFbeta (Montrer TGFB1 Anticorps) receptors, TGFBR1 (Montrer TGFBR1 Anticorps) and TGFBR2...transfection of anti-miRNAs against miR (Montrer MLXIP Anticorps)-202-5p resulted in increased TGFBR1 (Montrer TGFBR1 Anticorps) and TGFBR2 protein expressions and induced EMT (Montrer ITK Anticorps) characteristics in these cells. In stellate pancreatic cells, miR (Montrer MLXIP Anticorps)-202 overexpression slowed growth as well as reduced stromal extracellular membrane matrix protein expression

  9. Results show that TGFbR2 expression decreases in human gastric cancer (GC) tissue specimens and indicate that the expression of TGFbR2 is mainly dependent on post-transcriptional regulators in GC through miR (Montrer MLXIP Anticorps)-155 binding to the 3'-UTR (Montrer UTS2R Anticorps) of its mRNA.

  10. miR (Montrer MLXIP Anticorps)-130a-3p might play a critical role in negatively regulating hepatic stellate cell activation and proliferation in the progression of nonalcoholic fibrosing steatohepatitis by directly targeting TGFBR1 (Montrer TGFBR1 Anticorps) and TGFBR2 via the TGF-beta (Montrer TGFB1 Anticorps)/SMAD (Montrer SMAD1 Anticorps) signaling pathway.

Mouse (Murine) Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2) interaction partners

  1. Taken together, these results indicate that eIF6 (Montrer EIF6 Anticorps) may be involved in external mechanical force-mediated murine dermal fibroblast function at least partly through the TGF-beta1 (Montrer TGFB1 Anticorps)/TGFBR1 (Montrer TGFBR1 Anticorps)/TGFBR2 pathway.

  2. miR (Montrer MLXIP Anticorps)-130a-3p might play a critical role in negatively regulating hepatic stellate cell activation and proliferation in the progression of nonalcoholic fibrosing steatohepatitis by directly targeting TGFBR1 (Montrer TGFBR1 Anticorps) and TGFBR2 via the TGF-beta (Montrer TGFB1 Anticorps)/SMAD (Montrer SMAD1 Anticorps) signaling pathway.

  3. the molecular actions of TGFBR2 result in both SMAD4 (Montrer SMAD4 Anticorps)-dependent constraint of proliferation and SMAD4 (Montrer SMAD4 Anticorps)-independent activation of apoptosis

  4. altered Tgfbeta (Montrer TGFB1 Anticorps) signaling in cultured mouse and human enteroids supports further the in vivo data and reveals a critical role for Tgfbeta (Montrer TGFB1 Anticorps) signaling in generating precursor secretory cells. Overall, our data reveal a key role for Tgfbeta (Montrer TGFB1 Anticorps) signaling in regulating ISCs (Montrer NFS1 Anticorps) clonal dynamics and differentiation, with implications for cancer, tissue regeneration, and inflammation.

  5. In young Fbn1 (Montrer FBN1 Anticorps)(C1039G/+) mice, aortopathy develops in the absence of detectable alterations in smooth muscle cell (SMC (Montrer DYM Anticorps)) TGF-beta (Montrer TGFB1 Anticorps) signaling. Loss of physiologic SMC (Montrer DYM Anticorps) TGF-beta (Montrer TGFB1 Anticorps) signaling exacerbates MFS-associated aortopathy. Our data support a protective role for SMC (Montrer DYM Anticorps) TGF-beta (Montrer TGFB1 Anticorps) signaling during early development of MFS-associated aortopathy.

  6. The present study demonstrates that TGFbeta (Montrer TGFB1 Anticorps) responsiveness in the myeloid compartment is critical in controlling autoimmune encephalomyelitis, and that its specific deletion in monocyte-derived dendritic cells causes severe experimental autoimmune encephalomyelitis without remission.

  7. These results suggest proliferation and maturation of immature osteoblasts requires Tgfbr2 signaling and that decreased bone volume in Osx (Montrer SP7 Anticorps)-Cre;Tgfbr2(fl/fl (Montrer FLT3LG Anticorps)) mice is likely due to fewer mature osteoblasts.

  8. The authors identify ELMO1 (Montrer ELMO1 Anticorps) as a novel target of TGFbeta (Montrer TGFB1 Anticorps) signaling and show that restoration of Tgfbr2 results in a complete block of ELMO1 (Montrer ELMO1 Anticorps) in vivo. Knocking down Elmo1 (Montrer ELMO1 Anticorps) impairs metastasis of carcinoma cells to the lung, thereby providing insights into the mechanisms of progression of Tgfbr2-deficient invasive transition zone squamous cell carcinoma.

  9. removing TGF-b type II receptor in DA neurons also disrupts the balance in TGF-b1 expression in DA neurons and neighboring GABAergic neurons, which increases inhibitory input, reduces excitatory synaptic input, and alters phasic firing patterns in DA neurons

  10. PAR1 (Montrer F2R Anticorps) in its inactive unligated state functions as a scaffold for TGFbetaRII to downregulate TGF-beta (Montrer TGFB1 Anticorps) signaling, and thereby promote embryonic stem cell transition to functional endothelial cells.

Cow (Bovine) Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2) interaction partners

  1. These results indicate that high plasma cholesterol levels may contribute to the pathogenesis of certain diseases (e.g., atherosclerosis) by suppressing TGF-beta (Montrer TGFB1 Anticorps) responsiveness.

Rhesus Monkey Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2) interaction partners

  1. Expression of microRNA miR (Montrer MYLIP Anticorps)-155 was significantly upregulated in the oropharyngeal mucosa during chronic SIV infection and was coincident with downregulation of TGFbeta (Montrer TGFB1 Anticorps) receptor 2 (TGFbeta (Montrer TGFB1 Anticorps)-R2) and SMAD5 (Montrer SMAD5 Anticorps).

Zebrafish Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2) interaction partners

  1. The zebrafish T beta RII cDNA sequence is the first to be reported from a fish species, and it shows a high level of conservation at the kinase domain. mRNA expression of TGF-beta 1 (Montrer TGFB1 Anticorps), T beta RII.

TGFBR2 profil antigène

Profil protéine

This gene encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized.

Gene names and symbols associated with TGFBR2

  • transforming growth factor beta receptor 2 (TGFBR2) anticorps
  • transforming growth factor, beta receptor II (Tgfbr2) anticorps
  • transforming growth factor, beta receptor 2 (Tgfbr2) anticorps
  • transforming growth factor beta receptor 2b (tgfbr2b) anticorps
  • transforming growth factor beta receptor 2 (Tgfbr2) anticorps
  • 1110020H15Rik anticorps
  • AAT3 anticorps
  • AU042018 anticorps
  • cb537 anticorps
  • DNIIR anticorps
  • FAA3 anticorps
  • LDS1B anticorps
  • LDS2B anticorps
  • MFS2 anticorps
  • RIIC anticorps
  • RIIDN anticorps
  • TAAD2 anticorps
  • TBETA-RII anticorps
  • TbetaR-II anticorps
  • TbetaRII anticorps
  • TBR-II anticorps
  • TGF-beta 2 anticorps
  • TGFbeta-RII anticorps
  • tgfbr2 anticorps
  • Tgfbr2T anticorps
  • TGFBRII anticorps
  • TGFR-2 anticorps
  • wu:fj05c10 anticorps
  • zgc:110498 anticorps

Protein level used designations for TGFBR2

TGF-beta receptor type II , TGF-beta receptor type-2 , TGF-beta type II receptor , TGFR-2 , tbetaR-II , transforming growth factor-beta receptor type II , transforming growth factor-beta type II receptor , TGF-beta receptor type IIB , transforming growth factor beta receptor type IIC , TGF-beta receptor II , transforming growth factor, beta receptor II (70/80kDa) , transforming growth factor beta type II receptor , transforming growth factor, beta receptor II , transforming growth factor beta receptor 2 , TGF beta receptor type II , TGF-beta receptor type-2-like , transforming growth factor beta receptor type II , transforming growth factor beta, receptor 2 , transforming growth factor, beta receptor 2 , transforming growth factor, beta receptor IIT , transforming growth factor-b type II receptor , TGF-beta receptor 2 , transforming growth factor-beta receptor 2

GENE ID SPECIES
396399 Gallus gallus
7048 Homo sapiens
21813 Mus musculus
460243 Pan troglodytes
477039 Canis lupus familiaris
494191 Ovis aries
535376 Bos taurus
703088 Macaca mulatta
100031897 Monodelphis domestica
100033860 Equus caballus
100076965 Ornithorhynchus anatinus
100404359 Callithrix jacchus
100459236 Pongo abelii
100482939 Ailuropoda melanoleuca
81810 Rattus norvegicus
100220619 Taeniopygia guttata
100606849 Nomascus leucogenys
100038019 Sus scrofa
30739 Danio rerio
100718284 Cavia porcellus
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