anti-Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2) Anticorps

TGFBR2 encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. De plus, nous expédions TGFBR2 Kits (40) et TGFBR2 Protéines (32) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
TGFBR2 21813 Q62312
TGFBR2 81810 P38438
TGFBR2 7048 P37173
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Top anti-TGFBR2 Anticorps sur anticorps-enligne.fr

Showing 10 out of 222 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Humain Chèvre Inconjugué CyTOF, ELISA (Capture), FACS, IHC, Neut, WB Detection of TGF-beta RII in Human Lymphocytes by Flow Cytometry. Human blood-derived lymphocytes were labeled with Goat Anti-Human TGF-beta RII Antigen Affinity-purified Poly-clonal Antibody. TGF-beta RII in Human Pituitary. TGF-beta RII was detected in immersion fixed paraffin-embedded sections of human pituitary using Goat Anti-Human TGF-beta RII Antigen Affinity-purified Polyclonal Antibody. Lower panel shows a lack of labeling if primary antibodies are omitted and tissue is stained only with secondary antibody followed by incubation with detection reagents. 250 μg Connectez-vous pour afficher 8 to 9 Days
$463.45
Détails
Humain Lapin Inconjugué WB 100 μg Connectez-vous pour afficher 4 to 6 Days
$240.00
Détails
Boeuf (Vache) Lapin Inconjugué WB <b>WB Suggested Anti-TGFBR2 Antibody Titration: </b>5.0ug/ml<br><b>Positive Control: </b>HepG2 cell lysate 100 μL Connectez-vous pour afficher 2 to 3 Days
$229.00
Détails
Humain Lapin Inconjugué WB Western blot analysis of TGFBR2 expression in HepG2 (A), A549 (B), TF1 (C), KNRK (D) whole cell lysates. 200 μL Connectez-vous pour afficher 13 to 14 Days
$487.50
Détails
Humain Lapin Inconjugué WB Western blot analysis of TGFBR2 (pS225) expression in A549 (A), NIH3T3L1 (B), KNRK (C), HepG2 (D) whole cell lysates. 200 μL Connectez-vous pour afficher 13 to 14 Days
$575.00
Détails
Humain Souris Fluorescein FACS Detection of TGF-beta RII in NS0 Mouse Cell Line Transfected with TGF-beta RII by Flow Cytometry. NS0 mouse myeloma cell line transfected with TGF-beta RII was stained with Mouse Anti-Human TGF-beta RII Fluorescein-conjugated Monoclonal Antibody. 25 Tests Connectez-vous pour afficher 8 to 9 Days
$147.20
Détails
Humain Souris PE FACS Detection of TGF-beta RII in NS0 Mouse Cell Line transfected with TGF-beta RII by Flow Cytometry. NS0 mouse myeloma cell line transfected with TGF-beta RII was stained with Mouse Anti-Human TGF-beta RII PE-conjugated Monoclonal Antibody. 25 Tests Connectez-vous pour afficher 8 to 9 Days
$179.40
Détails
Souris Chèvre Fluorescein FACS Detection of TGF-beta RII in Mouse Splenocytes by Flow Cytometry. Mouse splenocytes were stained with Goat Anti-Mouse TGF-beta RII Fluorescein-conjugated Antigen Affinity-purified Polyclonal Antibody. 25 Tests Connectez-vous pour afficher 8 to 9 Days
$147.20
Détails
Humain Chèvre PE FACS Detection of TGF-beta RII in Human Blood Lymphocytes by Flow Cytometry. Human peripheral blood lymphocytes were stained with Goat Anti-Human TGF-beta RII PE-conjugated Antigen Affinity-purified Polyclonal Antibody. 25 Tests Connectez-vous pour afficher 8 to 9 Days
$179.40
Détails
Souris Chèvre PE FACS Detection of TGF-beta RII in Mouse Splenocytes by Flow Cytometry. Mouse splenocytes were stained with Goat Anti-Mouse TGF-beta RII PE-conjugated Antigen Affinity-purified Polyclonal Antibody. 25 Tests Connectez-vous pour afficher 8 to 9 Days
$179.40
Détails

TGFBR2 Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
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anti-TGFBR2 Anticorps mieux référencés

  1. Human Polyclonal TGFBR2 Primary Antibody pour CyTOF, ELISA (Capture) - ABIN4900595 : Wu, Majeed, Evans, Camus, Wong, Schollmeier, Park, Muppidi, Reboldi, Parham, Cyster, Brodsky: Clathrin light chains' role in selective endocytosis influences antibody isotype switching. dans Proceedings of the National Academy of Sciences of the United States of America 2016 (PubMed)
    Show all 16 Pubmed References

  2. Mouse (Murine) Polyclonal TGFBR2 Primary Antibody pour FACS - ABIN4898045 : Lewis, Macal, Hesser, Zuñiga et al.: Constitutive but not inducible attenuation of transforming growth factor β signaling increases natural killer cell responses without directly affecting dendritic cells early after persistent viral ... dans Journal of virology 2015 (PubMed)
    Show all 6 Pubmed References

  3. Mouse (Murine) Polyclonal TGFBR2 Primary Antibody pour FACS - ABIN4898046 : Rani, Smulian, Greaves, Hogan, Herbert: TGF-β limits IL-33 production and promotes the resolution of colitis through regulation of macrophage function. dans European journal of immunology 2011 (PubMed)
    Show all 6 Pubmed References

  4. Mouse (Murine) Polyclonal TGFBR2 Primary Antibody pour CyTOF, FACS - ABIN4900597 : Liu, Bi, Xue, Zhang, Yang, Chen, Lu, Zhang, Liu, Wang, Wang, Chu, Yang: Dendritic cell SIRT1-HIF1α axis programs the differentiation of CD4+ T cells through IL-12 and TGF-β1. dans Proceedings of the National Academy of Sciences of the United States of America 2015 (PubMed)
    Show all 4 Pubmed References

  5. Mouse (Murine) Polyclonal TGFBR2 Primary Antibody pour FACS, WB - ABIN4900596 : Denton, Zheng, Evans, Shi-wen, Ong, Fisher, Lazaridis, Abraham, Black, de Crombrugghe et al.: Fibroblast-specific expression of a kinase-deficient type II transforming growth factor beta (TGFbeta) receptor leads to paradoxical activation of TGFbeta signaling pathways with fibrosis in ... dans The Journal of biological chemistry 2003 (PubMed)
    Show all 4 Pubmed References

  6. Human Polyclonal TGFBR2 Primary Antibody pour IF (p), IHC (p) - ABIN725225 : Abdelmagid, Belcher, Moussa, Lababidi, Sondag, Novak, Sanyurah, Frara, Razmpour, Del Carpio-Cano, Safadi: Mutation in osteoactivin decreases bone formation in vivo and osteoblast differentiation in vitro. dans The American journal of pathology 2014 (PubMed)
    Show all 3 Pubmed References

  7. Human Polyclonal TGFBR2 Primary Antibody pour IHC, ELISA - ABIN1585382 : Li, Martijn, Cui, Essaghir, Luque, Demoulin, Castaño, Öberg, Giandomenico: The somatostatin analogue octreotide inhibits growth of small intestine neuroendocrine tumour cells. dans PLoS ONE 2012 (PubMed)
    Show all 2 Pubmed References

  8. Human Polyclonal TGFBR2 Primary Antibody pour ICC, IHC (fro) - ABIN407857 : Phatnani, Guarnieri, Friedman, Carrasco, Muratet, OKeeffe, Nwakeze, Pauli-Behn, Newberry, Meadows, Tapia, Myers, Maniatis: Intricate interplay between astrocytes and motor neurons in ALS. dans Proceedings of the National Academy of Sciences of the United States of America 2013 (PubMed)
    Show all 2 Pubmed References

  9. Mouse (Murine) Polyclonal TGFBR2 Primary Antibody pour FACS - ABIN4898037 : Gallo, Loch, Habashi, Calderon, Chen, Bedja, van Erp, Gerber, Parker, Sauls, Judge, Cooke, Lindsay, Rouf, Myers, ap Rhys, Kent, Norris, Huso, Dietz: Angiotensin II-dependent TGF-β signaling contributes to Loeys-Dietz syndrome vascular pathogenesis. dans The Journal of clinical investigation 2014 (PubMed)
    Show all 2 Pubmed References

  10. Mouse (Murine) Polyclonal TGFBR2 Primary Antibody pour FACS - ABIN4898038 : Zhou, Dong, Zhang, Chen, Zhu, Li, Song, Xu, Zhang, Yang, Li, Liu, Sun: MicroRNAs are implicated in the suppression of CD4+CD25− conventional T cell proliferation by CD4+CD25+ regulatory T cells. dans Molecular immunology 2015 (PubMed)
    Show all 2 Pubmed References

Plus d’anticorps contre TGFBR2 partenaires d’interaction

Rhesus Monkey Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2) interaction partners

  1. Expression of microRNA miR (Montrer MYLIP Anticorps)-155 was significantly upregulated in the oropharyngeal mucosa during chronic SIV infection and was coincident with downregulation of TGFbeta (Montrer TGFB1 Anticorps) receptor 2 (TGFbeta (Montrer TGFB1 Anticorps)-R2) and SMAD5 (Montrer SMAD5 Anticorps).

Mouse (Murine) Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2) interaction partners

  1. miR (Montrer MLXIP Anticorps)-130a-3p might play a critical role in negatively regulating hepatic stellate cell activation and proliferation in the progression of nonalcoholic fibrosing steatohepatitis by directly targeting TGFBR1 (Montrer TGFBR1 Anticorps) and TGFBR2 via the TGF-beta (Montrer TGFB1 Anticorps)/SMAD (Montrer SMAD1 Anticorps) signaling pathway.

  2. the molecular actions of TGFBR2 result in both SMAD4 (Montrer SMAD4 Anticorps)-dependent constraint of proliferation and SMAD4 (Montrer SMAD4 Anticorps)-independent activation of apoptosis

  3. altered Tgfbeta (Montrer TGFB1 Anticorps) signaling in cultured mouse and human enteroids supports further the in vivo data and reveals a critical role for Tgfbeta (Montrer TGFB1 Anticorps) signaling in generating precursor secretory cells. Overall, our data reveal a key role for Tgfbeta (Montrer TGFB1 Anticorps) signaling in regulating ISCs (Montrer NFS1 Anticorps) clonal dynamics and differentiation, with implications for cancer, tissue regeneration, and inflammation.

  4. In young Fbn1 (Montrer FBN1 Anticorps)(C1039G/+) mice, aortopathy develops in the absence of detectable alterations in smooth muscle cell (SMC (Montrer DYM Anticorps)) TGF-beta (Montrer TGFB1 Anticorps) signaling. Loss of physiologic SMC (Montrer DYM Anticorps) TGF-beta (Montrer TGFB1 Anticorps) signaling exacerbates MFS-associated aortopathy. Our data support a protective role for SMC (Montrer DYM Anticorps) TGF-beta (Montrer TGFB1 Anticorps) signaling during early development of MFS-associated aortopathy.

  5. The present study demonstrates that TGFbeta (Montrer TGFB1 Anticorps) responsiveness in the myeloid compartment is critical in controlling autoimmune encephalomyelitis, and that its specific deletion in monocyte-derived dendritic cells causes severe experimental autoimmune encephalomyelitis without remission.

  6. These results suggest proliferation and maturation of immature osteoblasts requires Tgfbr2 signaling and that decreased bone volume in Osx (Montrer SP7 Anticorps)-Cre;Tgfbr2(fl/fl (Montrer FLT3LG Anticorps)) mice is likely due to fewer mature osteoblasts.

  7. The authors identify ELMO1 (Montrer ELMO1 Anticorps) as a novel target of TGFbeta (Montrer TGFB1 Anticorps) signaling and show that restoration of Tgfbr2 results in a complete block of ELMO1 (Montrer ELMO1 Anticorps) in vivo. Knocking down Elmo1 (Montrer ELMO1 Anticorps) impairs metastasis of carcinoma cells to the lung, thereby providing insights into the mechanisms of progression of Tgfbr2-deficient invasive transition zone squamous cell carcinoma.

  8. removing TGF-b type II receptor in DA neurons also disrupts the balance in TGF-b1 expression in DA neurons and neighboring GABAergic neurons, which increases inhibitory input, reduces excitatory synaptic input, and alters phasic firing patterns in DA neurons

  9. PAR1 (Montrer F2R Anticorps) in its inactive unligated state functions as a scaffold for TGFbetaRII to downregulate TGF-beta (Montrer TGFB1 Anticorps) signaling, and thereby promote embryonic stem cell transition to functional endothelial cells.

  10. Cell-intrinsic TGFbeta-RII signaling limits CD4 (Montrer CD4 Anticorps) T cell proliferation but not prototypical T helper subset differentiation early after chronic lymphocytic choriomeningitis virus infection.

Human Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2) interaction partners

  1. Results show that TGFbR2 expression decreases in human gastric cancer (GC) tissue specimens and indicate that the expression of TGFbR2 is mainly dependent on post-transcriptional regulators in GC through miR (Montrer MLXIP Anticorps)-155 binding to the 3'-UTR (Montrer UTS2R Anticorps) of its mRNA.

  2. miR (Montrer MLXIP Anticorps)-130a-3p might play a critical role in negatively regulating hepatic stellate cell activation and proliferation in the progression of nonalcoholic fibrosing steatohepatitis by directly targeting TGFBR1 (Montrer TGFBR1 Anticorps) and TGFBR2 via the TGF-beta (Montrer TGFB1 Anticorps)/SMAD (Montrer SMAD1 Anticorps) signaling pathway.

  3. This study demonstrated that Increased Transforming Growth Factor beta2 (Montrer TGFB2 Anticorps) in the Neocortex of Alzheimer's Disease and Dementia with Lewy Bodies is Correlated with Disease Severity and Soluble Abeta42 Load.

  4. Abnormal expression of TGF-beta type II receptor isoforms contributes to prognosis in acute myeloid leukemia (Montrer BCL11A Anticorps).

  5. Loeys-Dietz syndrome patients with confirmed mutations in TGFBR1 (Montrer TGFBR1 Anticorps) or TGFBR2 had an increased prevalence of inflammatory bowel disease

  6. altered Tgfbeta (Montrer TGFB1 Anticorps) signaling in cultured mouse and human enteroids supports further the in vivo data and reveals a critical role for Tgfbeta (Montrer TGFB1 Anticorps) signaling in generating precursor secretory cells. Overall, our data reveal a key role for Tgfbeta (Montrer TGFB1 Anticorps) signaling in regulating ISCs (Montrer NFS1 Anticorps) clonal dynamics and differentiation, with implications for cancer, tissue regeneration, and inflammation.

  7. MiR (Montrer MLXIP Anticorps)-130 is up-regulated in gastric cancer (GC) tissues and directly targets TGF-beta type II receptor (TGFbetaR2).

  8. results suggest a role for prostatic expression of TGF-B, IL-1a (Montrer IL1A Anticorps), TGFBRI and TGFBRII as prognostic markers for prostate cancer. The rational combination of novel agents directed toward the inactivation of TGF-B, IL-1a (Montrer IL1A Anticorps), TGFBRI and TGFBRII could disrupt complementary tumor cell proliferation pathways.

  9. miR-17-5p negatively regulated TGFBR2 expression by directly binding to the 3'UTR (Montrer UTS2R Anticorps) of TGFBR2 mRNA, thereby promoting gastric cancer cell growth and migration.

  10. High TGFBR2 expression is associated with mesenchymal to epithelial transition of breast cancer.

Cow (Bovine) Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2) interaction partners

  1. These results indicate that high plasma cholesterol levels may contribute to the pathogenesis of certain diseases (e.g., atherosclerosis) by suppressing TGF-beta (Montrer TGFB1 Anticorps) responsiveness.

TGFBR2 profil antigène

Profil protéine

This gene encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized.

Gene names and symbols associated with TGFBR2

  • transforming growth factor beta receptor 2 (TGFBR2) anticorps
  • transforming growth factor, beta receptor II (Tgfbr2) anticorps
  • transforming growth factor, beta receptor 2 (Tgfbr2) anticorps
  • anti-Mullerian hormone receptor, type II (AMHR2) anticorps
  • 1110020H15Rik anticorps
  • AAT3 anticorps
  • AU042018 anticorps
  • DNIIR anticorps
  • FAA3 anticorps
  • LDS1B anticorps
  • LDS2B anticorps
  • MFS2 anticorps
  • RIIC anticorps
  • RIIDN anticorps
  • TAAD2 anticorps
  • TBETA-RII anticorps
  • TbetaR-II anticorps
  • TbetaRII anticorps
  • TBR-II anticorps
  • TGF-beta 2 anticorps
  • TGFbeta-RII anticorps
  • TGFBR2 anticorps
  • Tgfbr2T anticorps
  • TGFBRII anticorps
  • TGFR-2 anticorps

Protein level used designations for TGFBR2

transforming growth factor, beta receptor II (70/80kDa) , transforming growth factor beta type II receptor , transforming growth factor, beta receptor II , transforming growth factor beta receptor 2 , TGF-beta receptor type-2 , TGF beta receptor type II , TGF-beta receptor type-2-like , TGF-beta receptor II , TGF-beta receptor type II , TGF-beta type II receptor , TGFR-2 , transforming growth factor-beta receptor type II , tbetaR-II , transforming growth factor beta receptor type II , transforming growth factor beta, receptor 2 , transforming growth factor, beta receptor 2 , transforming growth factor, beta receptor IIT , transforming growth factor-b type II receptor , transforming growth factor-beta type II receptor , TGF-beta receptor type IIB , transforming growth factor beta receptor type IIC

GENE ID SPECIES
460243 Pan troglodytes
477039 Canis lupus familiaris
494191 Ovis aries
703088 Macaca mulatta
100031897 Monodelphis domestica
100033860 Equus caballus
100076965 Ornithorhynchus anatinus
100404359 Callithrix jacchus
100459236 Pongo abelii
100482939 Ailuropoda melanoleuca
100220619 Taeniopygia guttata
100606849 Nomascus leucogenys
100038019 Sus scrofa
21813 Mus musculus
81810 Rattus norvegicus
396399 Gallus gallus
7048 Homo sapiens
535376 Bos taurus
424261 Gallus gallus
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