Transforming Growth Factor beta Regulator 1 Protéines (TBRG1)

Acts as a growth inhibitor. De plus, nous expédions Transforming Growth Factor beta Regulator 1 Anticorps (49) et et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
TBRG1 21376 Q3UB74
TBRG1 84897 Q3YBR2
TBRG1 300521 Q5PQK8
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Top Transforming Growth Factor beta Regulator 1 Protéines sur anticorps-enligne.fr

Showing 6 out of 6 products:

Catalogue No. Origin Source Conjugué Images Quantité Livraison Prix Détails
Cellules d'insectes Humain His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 50 Days
$6,749.58
Détails
Cellules d'insectes Souris His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 50 Days
$6,749.58
Détails
Wheat germ Humain GST tag 10 μg 11 to 12 Days
$414.29
Détails
HEK-293 Cells Humain Myc-DYKDDDDK Tag Validation with Western Blot 20 μg 11 Days
$888.80
Détails
Levure Rat His tag   1 mg 60 to 71 Days
$3,122.17
Détails
Levure Xenopus tropicalis His tag   1 mg 60 to 71 Days
$3,135.00
Détails

TBRG1 Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Mouse (Murine)

Human , ,
, ,
Rat (Rattus)

Plus protéines pour Transforming Growth Factor beta Regulator 1 (TBRG1) partenaires d'interaction

Mouse (Murine) Transforming Growth Factor beta Regulator 1 (TBRG1) interaction partners

  1. The data provides a useful resource for exploring Myst2 and Niam essential cellular functions and should contribute to deeper understanding of organism early development and survival as well as cancer.

  2. NIAM down-regulation in vivo results in a significant predisposition to developing benign tumors or early stage cancers.

  3. novel protein with tumor suppressor-like behaviors and functional links to ARF-MDM2-p53 signaling

Human Transforming Growth Factor beta Regulator 1 (TBRG1) interaction partners

  1. In primary B-cell lymphoma NIAM-positive cases have significant lower levels of miR-155 as compared to NIAM-negative cases, suggesting that NIAM is regulated by miR-155 in primary B-cell lymphoma.

  2. NIAM regulates 2 critical pathways that control p53 function and are altered in human cancers, implying an important role for NIAM in tumorigenesis.

  3. Sructure of a fragment of TBRG1 was shown to encompasses two motifs. The FYRN and FYRC regions each form part of a single folded module (the FYR domain), which adopts a novel alpha + beta fold.

  4. novel protein with tumor suppressor-like behaviors and functional links to ARF-MDM2-p53 signaling

  5. NIAM is a nuclear interactor of ARF and Mdm2

Profil protéine Transforming Growth Factor beta Regulator 1 (TBRG1)

Profil protéine

Acts as a growth inhibitor. Can activate p53/TP53, causes G1 arrest and collaborates with CDKN2A to restrict proliferation, but does not require either protein to inhibit DNA synthesis. Redistributes CDKN2A into the nucleoplasm. Involved in maintaining chromosomal stability.

Gene names and symbols associated with TBRG1

  • transforming growth factor beta regulator 1 (TBRG1)
  • transforming growth factor beta regulator 1 (tbrg1)
  • transforming growth factor beta regulator 1 (CC1G_08054)
  • transforming growth factor beta regulator 1 L homeolog (tbrg1.L)
  • transforming growth factor beta regulated gene 1 (Tbrg1)
  • transforming growth factor beta regulator 1 (Tbrg1)
  • AA408552 Protéine
  • AA409675 Protéine
  • mFLJ00213 Protéine
  • MGC89629 Protéine
  • NIAM Protéine
  • TB-5 Protéine

Protein level used designations for TBRG1

transforming growth factor beta regulator 1 , transforming growth factor beta regulator 1-like , nuclear interactor of ARF and Mdm2 , nuclear interactor of ARF and MDM2 , transforming growth factor beta regulated gene 1

GENE ID SPECIES
100064183 Equus caballus
466838 Pan troglodytes
493502 Xenopus (Silurana) tropicalis
6012077 Coprinopsis cinerea okayama7130
100015447 Monodelphis domestica
100049131 Xenopus laevis
100350384 Oryctolagus cuniculus
100397909 Callithrix jacchus
100456056 Pongo abelii
100587645 Nomascus leucogenys
21376 Mus musculus
84897 Homo sapiens
489312 Canis lupus familiaris
100521637 Sus scrofa
507460 Bos taurus
300521 Rattus norvegicus
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