anti-Transient Receptor Potential Cation Channel, Subfamily C, Member 5 (TRPC5) Anticorps

TRPC5 belongs to the transient receptor family. De plus, nous expédions Transient Receptor Potential Cation Channel, Subfamily C, Member 5 Protéines (7) et et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
TRPC5 7224 Q9UL62
TRPC5 22067 Q9QX29
TRPC5 140933  
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Top anti-Transient Receptor Potential Cation Channel, Subfamily C, Member 5 Anticorps sur anticorps-enligne.fr

Showing 10 out of 124 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Livraison Prix Détails
Humain Souris FITC AA, IHC, IP, WB 100 μg 3 to 4 Days
$504.40
Détails
Humain Lapin Inconjugué WB Anti- TRPC5 Picoband antibody, Western blotting All lanes: Anti TRPC5  at 0.5ug/ml Lane 1: HELA Whole Cell Lysate at 40ug Lane 2: U87 Whole Cell Lysate at 40ug Lane 3: COLO320 Whole Cell Lysate at 40ug Predicted bind size: 111KD Observed bind size: 111KD Anti- TRPC5 Picoband antibody, Western blotting All lanes: Anti TRPC5  at 0.5ug/ml WB: Recombinant Human TRPC5 Protein 0.5ng Predicted bind size: 50KD Observed bind size: 50KD 100 μg 4 to 6 Days
$240.00
Détails
Humain Souris APC AA, IHC, IP, WB Immunohistochemistry analysis using Mouse Anti-TrpC5 Monoclonal Antibody, Clone S67-15 . Tissue: Brain Slice. Species: Mouse. Fixation: 10% Formalin Solution for 12-24 hours at RT. Primary Antibody: Mouse Anti-TrpC5 Monoclonal Antibody  at 1:1000 for 1 hour at RT. Secondary Antibody: HRP/DAB Detection System: Biotinylated Goat Anti-Mouse, Streptavidin Peroxidase, DAB Chromogen (brown) for 30 minutes at RT. Counterstain: Mayer Hematoxylin (purple/blue) nuclear stain at 250-500 µl for 5 minutes at RT. Localization: Nuclear staining. Magnification: 10X. Western Blot analysis of Rat Brain Membrane showing detection of ~110 kDa TrpC5 protein using Mouse Anti-TrpC5 Monoclonal Antibody, Clone S67-15 . Lane 1: Molecular Weight Ladder (MW). Lane 2: Rat Brain Membrane cell lysate. Load: 20 µg. Block: 2% BSA and 2% Skim Milk in 1X TBST. Primary Antibody: Mouse Anti-TrpC5 Monoclonal Antibody  at 1:1000 for 16 hours at 4°C. Secondary Antibody: Goat Anti-Mouse IgG: HRP at 1:100 for 60 min at RT. Color Development: ECL solution for 6 min in RT. Predicted/Observed Size: ~110 kDa. Other Band(s): 160kDa, 60kDa. 100 μg 3 to 4 Days
$513.50
Détails
Humain Souris PerCP AA, IHC, IP, WB Immunohistochemistry analysis using Mouse Anti-TrpC5 Monoclonal Antibody, Clone S67-15 . Tissue: Brain Slice. Species: Mouse. Fixation: 10% Formalin Solution for 12-24 hours at RT. Primary Antibody: Mouse Anti-TrpC5 Monoclonal Antibody  at 1:1000 for 1 hour at RT. Secondary Antibody: HRP/DAB Detection System: Biotinylated Goat Anti-Mouse, Streptavidin Peroxidase, DAB Chromogen (brown) for 30 minutes at RT. Counterstain: Mayer Hematoxylin (purple/blue) nuclear stain at 250-500 µl for 5 minutes at RT. Localization: Nuclear staining. Magnification: 10X. Western Blot analysis of Rat Brain Membrane showing detection of ~110 kDa TrpC5 protein using Mouse Anti-TrpC5 Monoclonal Antibody, Clone S67-15 . Lane 1: Molecular Weight Ladder (MW). Lane 2: Rat Brain Membrane cell lysate. Load: 20 µg. Block: 2% BSA and 2% Skim Milk in 1X TBST. Primary Antibody: Mouse Anti-TrpC5 Monoclonal Antibody  at 1:1000 for 16 hours at 4°C. Secondary Antibody: Goat Anti-Mouse IgG: HRP at 1:100 for 60 min at RT. Color Development: ECL solution for 6 min in RT. Predicted/Observed Size: ~110 kDa. Other Band(s): 160kDa, 60kDa. 100 μg 3 to 4 Days
$513.50
Détails
Humain Souris Atto 488 AA, IHC, IP, WB Immunohistochemistry analysis using Mouse Anti-TrpC5 Monoclonal Antibody, Clone S67-15 . Tissue: Brain Slice. Species: Mouse. Fixation: 10% Formalin Solution for 12-24 hours at RT. Primary Antibody: Mouse Anti-TrpC5 Monoclonal Antibody  at 1:1000 for 1 hour at RT. Secondary Antibody: HRP/DAB Detection System: Biotinylated Goat Anti-Mouse, Streptavidin Peroxidase, DAB Chromogen (brown) for 30 minutes at RT. Counterstain: Mayer Hematoxylin (purple/blue) nuclear stain at 250-500 µl for 5 minutes at RT. Localization: Nuclear staining. Magnification: 10X. Western Blot analysis of Rat Brain Membrane showing detection of ~110 kDa TrpC5 protein using Mouse Anti-TrpC5 Monoclonal Antibody, Clone S67-15 . Lane 1: Molecular Weight Ladder (MW). Lane 2: Rat Brain Membrane cell lysate. Load: 20 µg. Block: 2% BSA and 2% Skim Milk in 1X TBST. Primary Antibody: Mouse Anti-TrpC5 Monoclonal Antibody  at 1:1000 for 16 hours at 4°C. Secondary Antibody: Goat Anti-Mouse IgG: HRP at 1:100 for 60 min at RT. Color Development: ECL solution for 6 min in RT. Predicted/Observed Size: ~110 kDa. Other Band(s): 160kDa, 60kDa. 100 μg 3 to 4 Days
$514.80
Détails
Humain Souris Atto 594 AA, IHC, IP, WB Immunohistochemistry analysis using Mouse Anti-TrpC5 Monoclonal Antibody, Clone S67-15 . Tissue: Brain Slice. Species: Mouse. Fixation: 10% Formalin Solution for 12-24 hours at RT. Primary Antibody: Mouse Anti-TrpC5 Monoclonal Antibody  at 1:1000 for 1 hour at RT. Secondary Antibody: HRP/DAB Detection System: Biotinylated Goat Anti-Mouse, Streptavidin Peroxidase, DAB Chromogen (brown) for 30 minutes at RT. Counterstain: Mayer Hematoxylin (purple/blue) nuclear stain at 250-500 µl for 5 minutes at RT. Localization: Nuclear staining. Magnification: 10X. Western Blot analysis of Rat Brain Membrane showing detection of ~110 kDa TrpC5 protein using Mouse Anti-TrpC5 Monoclonal Antibody, Clone S67-15 . Lane 1: Molecular Weight Ladder (MW). Lane 2: Rat Brain Membrane cell lysate. Load: 20 µg. Block: 2% BSA and 2% Skim Milk in 1X TBST. Primary Antibody: Mouse Anti-TrpC5 Monoclonal Antibody  at 1:1000 for 16 hours at 4°C. Secondary Antibody: Goat Anti-Mouse IgG: HRP at 1:100 for 60 min at RT. Color Development: ECL solution for 6 min in RT. Predicted/Observed Size: ~110 kDa. Other Band(s): 160kDa, 60kDa. 100 μg 3 to 4 Days
$514.80
Détails
Humain Souris Atto 565 AA, IHC, IP, WB Immunohistochemistry analysis using Mouse Anti-TrpC5 Monoclonal Antibody, Clone S67-15 . Tissue: Brain Slice. Species: Mouse. Fixation: 10% Formalin Solution for 12-24 hours at RT. Primary Antibody: Mouse Anti-TrpC5 Monoclonal Antibody  at 1:1000 for 1 hour at RT. Secondary Antibody: HRP/DAB Detection System: Biotinylated Goat Anti-Mouse, Streptavidin Peroxidase, DAB Chromogen (brown) for 30 minutes at RT. Counterstain: Mayer Hematoxylin (purple/blue) nuclear stain at 250-500 µl for 5 minutes at RT. Localization: Nuclear staining. Magnification: 10X. Western Blot analysis of Rat Brain Membrane showing detection of ~110 kDa TrpC5 protein using Mouse Anti-TrpC5 Monoclonal Antibody, Clone S67-15 . Lane 1: Molecular Weight Ladder (MW). Lane 2: Rat Brain Membrane cell lysate. Load: 20 µg. Block: 2% BSA and 2% Skim Milk in 1X TBST. Primary Antibody: Mouse Anti-TrpC5 Monoclonal Antibody  at 1:1000 for 16 hours at 4°C. Secondary Antibody: Goat Anti-Mouse IgG: HRP at 1:100 for 60 min at RT. Color Development: ECL solution for 6 min in RT. Predicted/Observed Size: ~110 kDa. Other Band(s): 160kDa, 60kDa. 100 μg 3 to 4 Days
$514.80
Détails
Humain Souris Atto 633 AA, IHC, IP, WB Immunohistochemistry analysis using Mouse Anti-TrpC5 Monoclonal Antibody, Clone S67-15 . Tissue: Brain Slice. Species: Mouse. Fixation: 10% Formalin Solution for 12-24 hours at RT. Primary Antibody: Mouse Anti-TrpC5 Monoclonal Antibody  at 1:1000 for 1 hour at RT. Secondary Antibody: HRP/DAB Detection System: Biotinylated Goat Anti-Mouse, Streptavidin Peroxidase, DAB Chromogen (brown) for 30 minutes at RT. Counterstain: Mayer Hematoxylin (purple/blue) nuclear stain at 250-500 µl for 5 minutes at RT. Localization: Nuclear staining. Magnification: 10X. Western Blot analysis of Rat Brain Membrane showing detection of ~110 kDa TrpC5 protein using Mouse Anti-TrpC5 Monoclonal Antibody, Clone S67-15 . Lane 1: Molecular Weight Ladder (MW). Lane 2: Rat Brain Membrane cell lysate. Load: 20 µg. Block: 2% BSA and 2% Skim Milk in 1X TBST. Primary Antibody: Mouse Anti-TrpC5 Monoclonal Antibody  at 1:1000 for 16 hours at 4°C. Secondary Antibody: Goat Anti-Mouse IgG: HRP at 1:100 for 60 min at RT. Color Development: ECL solution for 6 min in RT. Predicted/Observed Size: ~110 kDa. Other Band(s): 160kDa, 60kDa. 100 μg 3 to 4 Days
$514.80
Détails
Humain Souris Atto 655 AA, IHC, IP, WB Immunohistochemistry analysis using Mouse Anti-TrpC5 Monoclonal Antibody, Clone S67-15 . Tissue: Brain Slice. Species: Mouse. Fixation: 10% Formalin Solution for 12-24 hours at RT. Primary Antibody: Mouse Anti-TrpC5 Monoclonal Antibody  at 1:1000 for 1 hour at RT. Secondary Antibody: HRP/DAB Detection System: Biotinylated Goat Anti-Mouse, Streptavidin Peroxidase, DAB Chromogen (brown) for 30 minutes at RT. Counterstain: Mayer Hematoxylin (purple/blue) nuclear stain at 250-500 µl for 5 minutes at RT. Localization: Nuclear staining. Magnification: 10X. Western Blot analysis of Rat Brain Membrane showing detection of ~110 kDa TrpC5 protein using Mouse Anti-TrpC5 Monoclonal Antibody, Clone S67-15 . Lane 1: Molecular Weight Ladder (MW). Lane 2: Rat Brain Membrane cell lysate. Load: 20 µg. Block: 2% BSA and 2% Skim Milk in 1X TBST. Primary Antibody: Mouse Anti-TrpC5 Monoclonal Antibody  at 1:1000 for 16 hours at 4°C. Secondary Antibody: Goat Anti-Mouse IgG: HRP at 1:100 for 60 min at RT. Color Development: ECL solution for 6 min in RT. Predicted/Observed Size: ~110 kDa. Other Band(s): 160kDa, 60kDa. 100 μg 3 to 4 Days
$514.80
Détails
Humain Souris Atto 680 AA, IHC, IP, WB Immunohistochemistry analysis using Mouse Anti-TrpC5 Monoclonal Antibody, Clone S67-15 . Tissue: Brain Slice. Species: Mouse. Fixation: 10% Formalin Solution for 12-24 hours at RT. Primary Antibody: Mouse Anti-TrpC5 Monoclonal Antibody  at 1:1000 for 1 hour at RT. Secondary Antibody: HRP/DAB Detection System: Biotinylated Goat Anti-Mouse, Streptavidin Peroxidase, DAB Chromogen (brown) for 30 minutes at RT. Counterstain: Mayer Hematoxylin (purple/blue) nuclear stain at 250-500 µl for 5 minutes at RT. Localization: Nuclear staining. Magnification: 10X. Western Blot analysis of Rat Brain Membrane showing detection of ~110 kDa TrpC5 protein using Mouse Anti-TrpC5 Monoclonal Antibody, Clone S67-15 . Lane 1: Molecular Weight Ladder (MW). Lane 2: Rat Brain Membrane cell lysate. Load: 20 µg. Block: 2% BSA and 2% Skim Milk in 1X TBST. Primary Antibody: Mouse Anti-TrpC5 Monoclonal Antibody  at 1:1000 for 16 hours at 4°C. Secondary Antibody: Goat Anti-Mouse IgG: HRP at 1:100 for 60 min at RT. Color Development: ECL solution for 6 min in RT. Predicted/Observed Size: ~110 kDa. Other Band(s): 160kDa, 60kDa. 100 μg 3 to 4 Days
$514.80
Détails

anti-Transient Receptor Potential Cation Channel, Subfamily C, Member 5 Anticorps mieux référencés

  1. Mammalian Monoclonal TRPC5 Primary Antibody pour ISt, IHC - ABIN1305023 : Hong, Seo, Kwak, Jeon, Jang, Jeong, Myeong, Hwang, Ha, Kang, Lee, Yi, Kim, Jeon, Ryu, So: Increased TRPC5 glutathionylation contributes to striatal neuron loss in Huntington's disease. dans Brain : a journal of neurology 2015 (PubMed)
    Show all 18 Pubmed References

Plus d’anticorps contre Transient Receptor Potential Cation Channel, Subfamily C, Member 5 partenaires d’interaction

Zebrafish Transient Receptor Potential Cation Channel, Subfamily C, Member 5 (TRPC5) interaction partners

  1. findings reveal a novel signalling pathway involved in development of the semicircular canal system, and suggest a previously unrecognized role for NCS-1 in mitochondrial function via its association with several mitochondrial proteins.

Pig (Porcine) Transient Receptor Potential Cation Channel, Subfamily C, Member 5 (TRPC5) interaction partners

  1. Data found that the pig adrenal medulla expressed predominantly TRPC1, TRPC5, and TRPC6 transcripts. The expression level of these TRPCs was significantly elevated in the adrenal medulla from pigs with metabolic syndrome.

Human Transient Receptor Potential Cation Channel, Subfamily C, Member 5 (TRPC5) interaction partners

  1. the present study revealed that TRPC5, an initiator of autophagy, upregulated Temozolomide (TMZ)resistance via the CaMKKbeta/AMPKalpha/mTOR pathway and this indicated a novel therapeutic site for drug resistance in glioma chemotherapy.

  2. Silencing of TRPC5 and inhibition of autophagy reverses adriamycin drug resistance in breast carcinoma via CaMKKbeta/AMPKalpha/mTOR pathway.

  3. We demonstrated the essential role of glycolysis in TRPC5 induced chemoresistance in human CRC cells via maintaining [Ca(2+)] i homeostasis.

  4. induces the epithelial-mesenchymal transition through the HIF-1alpha-Twist signaling pathway to promote tumor metastasis in colon cancer

  5. TrpC5 causes a robust rise in [Ca2+]i, enhanced Wnt5a expression and nuclear translocation of beta-catenin, leading to reduced differentiation and enhanced cancer cell stemness.

  6. These findings suggest identification of an important experimental tool compound, which has much higher potency for inhibiting TRPC1/4/5 channels than previously reported agents, impressive specificity, and graded subtype selectivity within the TRPC1/4/5 channel family.

  7. that Arg-593, a residue located in the E4 loop near the TRPC5 extracellular Gd(3+) binding site, is critical for conferring the sensitivity to GPCR-Gq/11-PLC-dependent gating on TRPC5.

  8. Transient receptor potential canonical 5 (TRPC5) protects against pain and vascular inflammation in arthritis and joint inflammation.

  9. circulating exosome-carrying TRPC5 might act as a noninvasive chemoresistance marker and might serve as an adjuvant to the current imaging examination-based chemoresistance.

  10. The essential role of TrpC5 in GLUT1 induction and chemoresistance in colorectal cancer.

  11. TrpC5 plays an important role in VEGF-mediated tumor angiogenesis, suggesting its potential clinical value for anti-angiogenesis therapy

  12. TRPC5 mRNA and protein levels were up-regulated in focal cortical dysplasia cortical lesions.

  13. Suppressing TrpC5 expression decreased nuclear beta-catenin accumulation, reduced the induction of ABCB1, and reversed 5-fluorouracil neoplastic resistance.

  14. these results suggest that hypoosmotic cell-swelling activates Gq-coupled receptors, which in turn enhance the activation of TRPC5 by regulating this channel membrane trafficking

  15. Clemizole exhibits a sixfold selectivity for TRPC5.

  16. Riluzole can activate TRPC5 heterologously expressed in HEK293 cells as well as those endogenously expressed in the U-87 glioblastoma cell line.

  17. TrpC5-containing circulating extracellular vesicles may transfer chemoresistance.

  18. Microvesicles from tumor cells transferred TrpC5 to endothelial cells, inducing the expression of P-glycoprotein by activation of the transcription factor NFATc3 (nuclear factor of activated T cells isoform c3).

  19. the S4-S5 linker is a critical constituent of TRPC4/C5 channel gating and that disturbance of its sequence allows channel opening independent of any sensor domain.

  20. Data using recombinant proteins expressed in vascular endothelial cells suggest that SigmaR1 (sigma 1-type opioid receptor) is not involved in regulation of calcium signaling via TRPC5/TRPM3 (transient receptor potential cation channels C5/M3).

Mouse (Murine) Transient Receptor Potential Cation Channel, Subfamily C, Member 5 (TRPC5) interaction partners

  1. TRPC5 is a novel therapeutic target against oxidative neuronal injury in prolonged seizures and that NU6027 is a potent inhibitor of TRPC5

  2. Overall, this study reveals that overexpression or activation of TRPC5 is not the culprit for de novo or aggravating proteinuric kidney disease.

  3. a potential regulatory link between nuclear factor of activated T cell isoform c3 and angiopoietin-1 that could provide the mechanistic basis for the angiogenic function of TRPC5. Importantly, treatment with riluzole, which can activate TRPC5 in endothelial cells, improved recovery from ischemia in mice.

  4. TRPC5 may not have a pivotal role in baroreflex regulation

  5. Results suggest that activation of transient receptor potential channel 5 (TRPC5) contributes to the development of cholestasis and associated dyslipidemia.

  6. TRPC5 channels represent a key pressure transducer in the baroreceptors and play an important role in maintaining blood pressure stability.

  7. These results indicate the contribution of heteromultimeric channels from TRPC1, TRPC4, and TRPC5 subunits to the regulation of mechanisms underlying spatial working memory and flexible relearning by facilitating proper synaptic transmission in hippocampal neurons.

  8. Transient receptor potential canonical 5 (TRPC5) protects against pain and vascular inflammation in arthritis and joint inflammation.

  9. that Arg-593, a residue located in the E4 loop near the TRPC5 extracellular Gd(3+) binding site, is critical for conferring the sensitivity to GPCR-Gq/11-PLC-dependent gating on TRPC5.

  10. novel functions of TRPC5 in regulating vascular aging

  11. TRPC5 contributes to depolarization of the plasma membrane in gonadotropes upon GnRH stimulation and increases the intracellular Ca2+ concentration via its own Ca2+ permeability and via the activation of voltage-gated Ca2+ channels.

  12. the antidepressant and anxiolytic-like effects of a newly identified TRPC4/C5 inhibitor, M084.

  13. Riluzole can activate TRPC5 heterologously expressed in HEK293 cells as well as those endogenously expressed in the U-87 glioblastoma cell line.

  14. Loss or inhibition of TRPC5 abrogates podocyte cytoskeletal remodeling, prevents Rac1 activation, & stabilizes synaptopodin. Genetic deletion or pharmacologic inhibition of TRPC5 protected mice from albuminuria.

  15. the S4-S5 linker is a critical constituent of TRPC4/C5 channel gating and that disturbance of its sequence allows channel opening independent of any sensor domain.

  16. Is unaltered in TRPC5 KO mice, but is abolished in TRPC1 KO and TRPC1/4 DKO mice.

  17. NEB cells selectively expressed the Ca(2+)-permeable osmo- and mechanosensitive TRPC5 in their apical membranes, whereas immunoreactivity for TRP vanilloid-4 and TRP melastatin-3 was abundant in virtually all other airway epithelial cells

  18. TRPC5 acts downstream of semaphorin signaling to cause changes in neuronal growth cone morphology and nervous system development.

  19. Agents that deplete intracellular Ca(2+) stores activate native heteromeric TRPC1/C5 channels in vascular smooth muscle cells.

  20. a novel function for TRPC5 that couples calcium signaling to a ubiquitin ligase pathway at the centrosome and thereby orchestrates dendrite patterning and connectivity in the brain

Cow (Bovine) Transient Receptor Potential Cation Channel, Subfamily C, Member 5 (TRPC5) interaction partners

  1. Nitrix oxide can negatively modulate endogenous TRPC5-containing channels through an indirect mechanism.

  2. analysis of a TRPC6-TRPC5 channel cascade that restricts endothelial cell movement

Transient Receptor Potential Cation Channel, Subfamily C, Member 5 (TRPC5) profil antigène

Profil protéine

This gene belongs to the transient receptor family. It encodes one of the seven mammalian TRPC (transient receptor potential channel) proteins. The encoded protein is a multi-pass membrane protein and is thought to form a receptor-activated non-selective calcium permeant cation channel. The protein is active alone or as a heteromultimeric assembly with TRPC1, TRPC3, and TRPC4. It also interacts with multiple proteins including calmodulin, CABP1, enkurin, Na(+)-H+ exchange regulatory factor (NHERF ), interferon-induced GTP-binding protein (MX1), ring finger protein 24 (RNF24), and SEC14 domain and spectrin repeat-containing protein 1 (SESTD1).

Gene names and symbols associated with TRPC5

  • transient receptor potential cation channel, subfamily C, member 5a (trpc5a) anticorps
  • transient receptor potential cation channel subfamily C member 5 (TRPC5) anticorps
  • transient receptor potential cation channel, subfamily C, member 5 (Trpc5) anticorps
  • CCE2 anticorps
  • trp anticorps
  • TRP-5 anticorps
  • TRP5 anticorps
  • Trpc5 anticorps
  • Trrp5 anticorps
  • wu:fi73f08 anticorps

Protein level used designations for TRPC5

transient receptor potential cation channel, subfamily C, member 5 , transient receptor potential channel subfamily C member 5 , CCE2 , rtrp5 , short transient receptor potential channel 5 , TRP-5 , hTRP5 , transient receptor potential channel 5 , transient receptor protein 5 , capacitative calcium entry channel 2 , mtrp5 , trp-related protein 5 , vtransient receptor potential cation channel, subfamily C, member 5

GENE ID SPECIES
557456 Danio rerio
422337 Gallus gallus
492072 Canis lupus familiaris
100037962 Sus scrofa
100009574 Oryctolagus cuniculus
7224 Homo sapiens
22067 Mus musculus
140933 Rattus norvegicus
407103 Bos taurus
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