Transmembrane 4 L Six Family Member 1 Protéines (TM4SF1)

The protein encoded by TM4SF1 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. De plus, nous expédions TM4SF1 Anticorps (71) et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
TM4SF1 4071 P30408
Rat TM4SF1 TM4SF1 295061  
TM4SF1 17112 Q64302
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Showing 3 out of 3 products:

Catalogue No. Origin Source Conjugué Images Quantité Fournisseur Livraison Prix Détails
Cellules d'insectes Souris rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Connectez-vous pour afficher 50 to 55 Days
$5,355.45
Détails
Cellules d'insectes Humain rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Connectez-vous pour afficher 50 to 55 Days
$7,626.01
Détails
Wheat germ Humain GST tag 10 μg Connectez-vous pour afficher 11 to 12 Days
$414.29
Détails

TM4SF1 Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Human ,
,
Mouse (Murine)

Plus protéines pour Transmembrane 4 L Six Family Member 1 (TM4SF1) partenaires d'interaction

Human Transmembrane 4 L Six Family Member 1 (TM4SF1) interaction partners

  1. TM4SF1 was recognized as a direct target for miR (Montrer MLXIP Protéines)-520f in hepatocellular carcinoma (HCC (Montrer FAM126A Protéines)) cells where its expression was found up-regulated and inversely correlated with that of mir (Montrer MLXIP Protéines)-520f.

  2. Results suggest that miR (Montrer MLXIP Protéines)-30a is an important regulator of TM4SF1, VEGF (Montrer VEGFA Protéines), and E-cadherin (Montrer CDH1 Protéines) for CRC (Montrer CALR Protéines) lymph node metastasis, a potential new therapeutic target in CRC (Montrer CALR Protéines).

  3. High TM4SF1 expression is associated with esophageal cancer.

  4. Replacement of the transmembrane 4 L six family protein TM4SF1 or TM4SF4 C-terminus with that of TM4SF5 increased spheroids growth, transwell migration, and invasive dissemination from spheroids in 3D collagen gels.

  5. Results indicate that the expression of transmembrane 4 L6 family member 1 (TM4SF1) is higher in pancreatic cancer tissues and pancreatic cancer cell lines than controls.

  6. Results show that TM4SF1 expression is elevated in colorectal cancer (CRC (Montrer CALR Protéines)), and associated with tumor stage and lymph node metastasis. Also, miR (Montrer MLXIP Protéines)-9 directly targeted its binding site in the TM4SF1 3'-UTR, which has a critical role in regulating CRC (Montrer CALR Protéines) cell migration. and invasion. Furthermore, miR (Montrer MLXIP Protéines)-9 regulated cell motility via suppressing

  7. The findings suggest that TM4SF1 is a surface membrane antigen that is highly expressed in pancreatic cancer cells and increases the chemoresistance to gemcitabine. TM4SF1 may be a promising target to overcome the chemoresistance of pancreatic cancer.

  8. TM4SF1 overexpression significantly contributed MDA-MB-231 cell migration but decreased apoptotic cells

  9. Study shows that TM4SF1 expression is associated with better prognosis in pancreatic cancer. Its loss contributes to the invasion and migration of pancreatic cancer cells.

  10. We found that miR (Montrer MLXIP Protéines)-203 was significantly downregulated in OSF (Montrer OSTF1 Protéines) tissues compared to that in normal buccal mucosa tissues, and that miR (Montrer MLXIP Protéines)-203 negatively regulated secreted SFRP4 (Montrer SFRP4 Protéines) and positively regulated TM4SF1

Mouse (Murine) Transmembrane 4 L Six Family Member 1 (TM4SF1) interaction partners

Profil protéine TM4SF1

Profil protéine

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface antigen and is highly expressed in different carcinomas.

Gene names and symbols associated with TM4SF1

  • transmembrane 4 L six family member 1 (TM4SF1)
  • transmembrane 4 L six family member 1 S homeolog (tm4sf1.S)
  • transmembrane 4 L six family member 1 (tm4sf1)
  • transmembrane 4 L six family member 1 (Tm4sf1)
  • transmembrane 4 superfamily member 1 (Tm4sf1)
  • H-L6 Protéine
  • L6 Protéine
  • M3s1 Protéine
  • MGC85546 Protéine
  • MM3 Protéine
  • TAAL6 Protéine

Protein level used designations for TM4SF1

transmembrane 4 L six family member 1 , transmembrane 4 superfamily member 1 , transmembrane 4 L6 family member 1 , membrane component chromosome 3 surface marker 1 , membrane component, chromosome 3, surface marker 1 , tumor-associated antigen L6 , Tumor-associated antigen L6 homolog , 12A8 target antigen , L6 antigen , membrane component chromosome 3 surface marker 1 homolog , membrane component, surface marker 1

GENE ID SPECIES
425046 Gallus gallus
447175 Xenopus laevis
460770 Pan troglodytes
485710 Canis lupus familiaris
533038 Bos taurus
100151707 Xenopus (Silurana) tropicalis
4071 Homo sapiens
295061 Rattus norvegicus
101833523 Mesocricetus auratus
100171795 Pongo abelii
17112 Mus musculus
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