anti-Tribbles Homolog 2 (Drosophila) (TRIB2) Anticorps

TRIB2 encodes one of three members of the Tribbles family. De plus, nous expédions Tribbles Homolog 2 (Drosophila) Protéines (12) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
TRIB2 28951 Q92519
TRIB2 217410 Q8K4K3
TRIB2 313974  
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Top anti-Tribbles Homolog 2 (Drosophila) Anticorps sur anticorps-enligne.fr

Showing 10 out of 67 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB <b>WB Suggested Anti-TRIB2 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>Human Liver 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Humain Souris Inconjugué FACS, IF, IHC (p), WB 100 μL Connectez-vous pour afficher 7 to 9 Days
$522.50
Détails
Humain Lapin Inconjugué ICC, IF, IHC, IHC (p), WB Immunofluorescence: TRIB2 Antibody  - Staining of human cell line A-431 shows positivity in cytoplasm and nucleus but excluded from the nucleoli. Western Blot: TRIB2 Antibody  - Analysis in human cell line K562. 0.1 mL Connectez-vous pour afficher 10 to 13 Days
$491.63
Détails
Humain Souris Inconjugué IHC (p), ELISA, WB 100 μg Connectez-vous pour afficher 7 to 9 Days
$537.17
Détails
Humain Souris Inconjugué IHC (p), RNAi, ELISA, WB Immunoperoxidase of monoclonal antibody to TRIB2 on formalin-fixed paraffin-embedded human colon. [antibody concentration 3 ug/ml] TRIB2 monoclonal antibody (M04), clone 1B1 Western Blot analysis of TRIB2 expression in Jurkat (ABIN1339540). 100 μg Connectez-vous pour afficher 11 to 12 Days
$440.00
Détails
Humain Lapin Inconjugué IHC (p), WB TRIB2 was detected in paraffin-embedded sections of human tonsil tissues using rabbit anti- TRIB2 Antigen Affinity purified polyclonal antibody at 1 μg/mL. The immunohistochemical section was developed using SABC method TRIB2 was detected in paraffin-embedded sections of rat spleen tissues using rabbit anti- TRIB2 Antigen Affinity purified polyclonal antibody at 1 μg/mL. The immunohistochemical section was developed using SABC method 100 μg Connectez-vous pour afficher 4 to 6 Days
$280.00
Détails
Roussette (Chauve-souris) Lapin Inconjugué WB 50 μg Connectez-vous pour afficher 7 to 9 Days
$551.83
Détails
Humain Lapin Inconjugué FACS, IHC (p), WB Western blot analysis of TRIB2 (arrow) using rabbit polyclonal TRIB2 N-term (ABIN652876). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the TRIB2 gene (Lane 2) . TRIB2 Antibody (N-term) (ABIN652876) IHC analysis in formalin fixed and paraffin embedded mouse brain followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Connectez-vous pour afficher 10 to 11 Days
$324.50
Détails
Roussette (Chauve-souris) Chèvre Inconjugué IHC (p) Colon, Human: Formalin-Fixed, Paraffin-Embedded (FFPE) Spleen, Human: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Connectez-vous pour afficher 7 to 9 Days
$484.00
Détails
Humain Lapin Inconjugué IF (p), IHC (p), WB 0.2 µg/100 µL Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000, Secondary: HRP conjugated Goat Anti-Rabbit IgG at 1: 5000, TMB staining, Read the data in Microplate Reader by 450 nm Formalin-fixed and paraffin embedded human lung cancer labeled with Anti-TRIB2 Polyclonal Antibody, Unconjugated  at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Connectez-vous pour afficher 3 to 7 Days
$306.90
Détails

TRIB2 Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
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anti-Tribbles Homolog 2 (Drosophila) Anticorps mieux référencés

  1. Human Monoclonal TRIB2 Primary Antibody pour IHC (p), RNAi - ABIN565396 : Wang, Zhang, Weng, Qiao, Ma, Xiao, Yu, Pan, Sun et al.: Impaired phosphorylation and ubiquitination by p70 S6 kinase (p70S6K) and Smad ubiquitination regulatory factor 1 (Smurf1) promote tribbles homolog 2 (TRIB2) stability and carcinogenic property in ... dans The Journal of biological chemistry 2013 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal TRIB2 Primary Antibody pour ICC, IF - ABIN4362344 : Sung, Francis, Arnold, Holland, Ernst, Angyal, Kiss-Toth: Enhanced macrophage tribbles-1 expression in murine experimental atherosclerosis. dans Biology 2014 (PubMed)

Plus d’anticorps contre Tribbles Homolog 2 (Drosophila) partenaires d’interaction

Xenopus laevis Tribbles Homolog 2 (Drosophila) (TRIB2) interaction partners

  1. tissues expressing the highest levels of Xtrb2 were most markedly affected by morpholino knockdown, with perturbation of neural crest and eye development

Human Tribbles Homolog 2 (Drosophila) (TRIB2) interaction partners

  1. O-GlcNAcylation of TRIB2 might be critical for diabetes-associated liver cancer.

  2. Tumors from resistant patients expressed the lowest levels of TRIB2. Downregulation of TRIB2 contributes to platin-resistance.

  3. our data show that excess p30 (Montrer CENPV Anticorps) cooperated with TRIB2 only in the presence of p42 (Montrer EPB42 Anticorps) to accelerate acute myeloid leukaemia (AML (Montrer RUNX1 Anticorps)), and the direct interaction and degradation of C/EBPa (Montrer CEBPA Anticorps) p42 (Montrer EPB42 Anticorps) is required for TRIB2-mediated AML (Montrer RUNX1 Anticorps).

  4. miR (Montrer MLXIP Anticorps)-206 and miR (Montrer MLXIP Anticorps)-140, as tumor suppressors, induced lung adenocarcinoma cell death and inhibited cell proliferation by modifying oncogenic TRIB2 promoter activity through p-Smad3 (Montrer SMAD3 Anticorps).

  5. Studied effect of TRIB2 SNP on the expression of genes involved in adaptive thermogenesis using messenger RNAs prepared from adipose tissues of Japanese adults. Of the five thermogenic genes, DIO2 (Montrer DIO2 Anticorps), CIDEA (Montrer CIDEA Anticorps), PPARGC1A, and PRDM16 (Montrer PRDM16 Anticorps) showed significantly higher transcript levels in SAT of individuals with the AA genotype relative to those with the AT + TT genotype.

  6. Data show that TRIB2-mediated degradation of CDC25C (Montrer CDC25C Anticorps) is associated with lysine-48-linked CDC25C (Montrer CDC25C Anticorps) polyubiquitination driven by the TRIB2 kinase-like domain.

  7. High TRIB2 reinforces the oncogenic transcriptional program controlled by the TAL1 (Montrer TAL1 Anticorps) complex in T-cell acute lymphoblastic leukemia.

  8. Studies suggest that pseudo-kinase family of tribbles (Montrer TRIB1 Anticorps) (TRIB) proteins TRIB1 (Montrer TRIB1 Anticorps), TRIB2 and TRIB3 (Montrer TRIB3 Anticorps) play roles in pathogenesis of rheumatoid arthritis (RA) and osteoarthritis.

  9. Studies suggest that pseudo-kinase family of tribbles (Montrer TRIB1 Anticorps) (TRIB) proteins TRIB1 (Montrer TRIB1 Anticorps), TRIB2 and TRIB3 (Montrer TRIB3 Anticorps) were involved in the pathogenesis of inflammation.

  10. Studies suggest that tribbles homolog 2 (Drosophila) protein (TRIB2) as a meaningful biomarker to both diagnose and stage melanoma.

Mouse (Murine) Tribbles Homolog 2 (Drosophila) (TRIB2) interaction partners

  1. The absence of a change in hypocretin (Montrer OX Anticorps) cell populations suggested that factors other than anti-TRIB2 antibody play a part in the loss of hypocretin (Montrer OX Anticorps) neurons in narcolepsy. The increased anti-TRIB2 antibody after the destruction of hypocretin (Montrer OX Anticorps) neurons suggest that anti-TRIB2 antibody in narcolepsy patients is the consequence rather than the inciting cause of hypocretin (Montrer OX Anticorps) cell destruction.

  2. These data indicate that Trib2 has a complex role in the pathogenesis of Notch (Montrer NOTCH1 Anticorps)-driven T-ALL, which may vary between different T-ALL subtypes.

  3. TRIB1 (Montrer TRIB1 Anticorps) and TRIB3 (Montrer TRIB3 Anticorps) are more strongly expressed than TRIB2 in cumulus cells (CC) surrounding oocytes from preovulatory follicles than in CC of immature ones.

  4. we identify the contribution of dysregulated C/EBPalpha (Montrer CEBPA Anticorps) and E2F1 (Montrer E2F1 Anticorps) to elevated Trib2 expression and leukemic cell survival

  5. Trib2 transduced hematopoietic stem cells developed acute myeloid leukemia (Montrer BCL11A Anticorps).

  6. Elevated Tribbles homolog 2-specific antibody levels in narcolepsy patients.

  7. Data identify Tribbles homolog 2 as an oncogene (Montrer RAB1A Anticorps) that induces acute myelogenous leukemia through a mechanism involving inactivation of C/EBPalpha (Montrer CEBPA Anticorps).

  8. describe suppression of adipocyte differentiation by TRBs Trib1 (Montrer TRIB1 Anticorps), Trib2, Trib3 (Montrer TRIB3 Anticorps)

  9. Mice reconstituted with HSC (Montrer FUT1 Anticorps) cotransduced with HoxA9 (Montrer HOXA9 Anticorps) and Trib2 had accelerated onset of AML (Montrer RUNX1 Anticorps) compared to either gene alone

  10. Linkage of Meis1 (Montrer MEIS1 Anticorps) leukemogenic activity to multiple downstream effectors including Trib2 and Ccl3 (Montrer CCL3 Anticorps).

Tribbles Homolog 2 (Drosophila) (TRIB2) profil antigène

Profil protéine

This gene encodes one of three members of the Tribbles family. The Tribbles members share a Trb domain, which is homologous to protein serine-threonine kinases, but lacks the active site lysine and probably lacks a catalytic function. The Tribbles proteins interact and modulate the activity of signal transduction pathways in a number of physiological and pathological processes. This Tribbles member induces apoptosis of cells mainly of the hematopoietic origin. It has been identified as a protein up-regulated by inflammatory stimuli in myeloid (THP-1) cells, and also as an oncogene that inactivates the transcription factor C/EBPalpha (CCAAT/enhancer-binding protein alpha) and causes acute myelogenous leukemia. Alternatively spliced transcript variants have been found for this gene.

Gene names and symbols associated with TRIB2

  • tribbles pseudokinase 2 (TRIB2) anticorps
  • tribbles pseudokinase 2 (trib2) anticorps
  • tribbles pseudokinase 2 S homeolog (trib2.S) anticorps
  • tribbles pseudokinase 2 (Trib2) anticorps
  • AW319517 anticorps
  • C5FW anticorps
  • GS3955 anticorps
  • RGD1564451 anticorps
  • TRB-2 anticorps
  • TRB2 anticorps
  • TRIB2 anticorps
  • xtrb2 anticorps
  • Xtrbl anticorps

Protein level used designations for TRIB2

tribbles homolog 2 (Drosophila) , tribbles homolog 2-like , tribbles homolog 2 , serine/threonine protein kinase , tribbles-like protein 2 , TRB-2

GENE ID SPECIES
459038 Pan troglodytes
100331041 Danio rerio
394677 Xenopus (Silurana) tropicalis
100357208 Oryctolagus cuniculus
100528799 Ictalurus punctatus
378920 Xenopus laevis
378919 Gallus gallus
28951 Homo sapiens
403884 Canis lupus familiaris
352960 Bos taurus
217410 Mus musculus
313974 Rattus norvegicus
100173599 Pongo abelii
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